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Organic Letters, ISSN 1523-7060, 02/2018, Volume 20, Issue 3, pp. 628 - 631
The first total synthesis of parvifloron F, a bioactive highly oxidized abietane diterpene, was achieved. The abietane skeleton was constructed by Lewis acid... 
CHEMISTRY, ORGANIC | PLECTRANTHUS | DITERPENOIDS | ANTIMICROBIAL ABIETANE | CYCLIZATION | TOTARANE | Cell Line, Tumor | Cell Proliferation - drug effects | Molecular Structure | Structure-Activity Relationship | Benz(a)Anthracenes | Humans
Journal Article
Molecules, ISSN 1420-3049, 11/2019, Volume 24, Issue 21, p. 4005
Seven new butanolides, peltanolides A–G (1–7), and two lignan glucosides, peltasides A (8) and B (9), along with eleven known compounds, 10–20, were isolated... 
hernandia nymphaeifolia | lignan glycosides | antiproliferative activity | butanolides
Journal Article
Molecular Oncology, ISSN 1574-7891, 06/2016, Volume 10, Issue 6, pp. 921 - 937
Triple-negative breast cancer (TNBC) is associated with high grade, metastatic phenotype, younger patient age, and poor prognosis. The discovery of an... 
Lung metastasis | Deoxyelephantopin | Paclitaxel | DET derivatives | Triple-negative breast cancer | Triple‐negative breast cancer | ANTITUMOR AGENTS | TUMOR INHIBITORS | APOPTOSIS | ONCOLOGY | GROWTH | CYTOTOXICITY | Apoptosis - drug effects | Antineoplastic Agents - chemical synthesis | Crystallography, X-Ray | Antineoplastic Agents - therapeutic use | Sesquiterpenes - chemical synthesis | Triple Negative Breast Neoplasms - drug therapy | Sesquiterpenes - therapeutic use | Lactones - chemical synthesis | Neoplasm Metastasis - prevention & control | Triple Negative Breast Neoplasms - pathology | Female | Breast - pathology | Lactones - chemistry | Cell Line | Sesquiterpenes - chemistry | Models, Molecular | Antineoplastic Agents - chemistry | Mice, SCID | Lactones - therapeutic use | Cell Movement - drug effects | Animals | Breast - drug effects | Neoplasm Metastasis - pathology | Cell Line, Tumor | Mice | Cell Cycle - drug effects | Antimitotic agents | Chemotherapy | Endothelial growth factors | Agricultural biotechnology | Analysis | Breast cancer | Metastasis | Drug therapy | Antineoplastic agents | Vascular endothelial growth factor | Cells | Cancer | Enzymes | Phenotypes | Motility | Tumor cell lines | Cancer therapies | Chromatography | Cell adhesion & migration | Metastases | Proteins | Natural products | Cell lines | Xenografts | Antitumor activity | Protein expression | Cell migration | Apoptosis
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2017, Volume 65, Issue 1, pp. 116 - 120
New clerodane diterpene, 16-hydroxy-pentandralactone (1) and known diterpene acuminolide (2) were isolated from the methanol extract of Vitex cofassus leaves.... 
clerodane diterpene | antiangiogenic activity | Vitex cofassus | antiproliferative activity | Antiproliferative activity | Clerodane diterpene | Antiangiogenic activity | NEGUNDO | TRIFOLIA | CHEMISTRY, MEDICINAL | LABDANE DITERPENOIDS | CHEMISTRY, MULTIDISCIPLINARY | RING | PHARMACOLOGY & PHARMACY | POLYALTHIA-VIRIDIS | LONGIFOLIA VAR. PENDULA | SOLIDAGO-ALTISSIMA | Cell Survival - drug effects | Diterpenes, Clerodane - isolation & purification | Human Umbilical Vein Endothelial Cells - drug effects | Human Umbilical Vein Endothelial Cells - metabolism | Vascular Endothelial Growth Factors - antagonists & inhibitors | Humans | Antineoplastic Agents, Phytogenic - chemistry | Structure-Activity Relationship | Diterpenes, Clerodane - chemistry | Neovascularization, Pathologic - pathology | Dose-Response Relationship, Drug | Vitex - chemistry | Neovascularization, Pathologic - drug therapy | Diterpenes, Clerodane - pharmacology | Cell Line, Tumor | Vascular Endothelial Growth Factors - metabolism | Cell Proliferation - drug effects | Molecular Structure | Antineoplastic Agents, Phytogenic - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Drug Screening Assays, Antitumor | Cell proliferation | Biotechnology | Nuclear magnetic resonance--NMR | Tumor cell lines | Drug resistance | Endothelial cells | Anticancer properties | Circular dichroism | Organic chemistry | Absolute configuration | Dichroism | Angiogenesis inhibitors | Vascular endothelial growth factor | Viability | Umbilical vein | Growth factors
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 03/2019, Volume 84, Issue 6, pp. 3239 - 3248
The first syntheses of 4-epi-parviflorons A, C, and E (4-epi-1-3) were achieved in 12-13 steps from commercially available (-)-abietic acid (5). All... 
CHEMISTRY, ORGANIC | TAXODIONE
Journal Article
Journal of Natural Products, ISSN 0163-3864, 10/2019, Volume 82, Issue 10, pp. 2852 - 2858
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 06/2016, Volume 15, Issue 6, pp. 1163 - 1176
Journal Article
Journal of natural products, ISSN 0163-3864, 08/2019, Volume 82, Issue 9, pp. 2368 - 2378
A CH OH-CH Cl (1:1) extract (N025439) of the leaves and twigs of furnished eight new compounds, - . Based on extensive 1D and 2D NMR spectroscopic data... 
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 12/2015, Volume 14, Issue 12 Supplement 2, pp. B175 - B175
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 09/2018, Volume 157, pp. 1143 - 1152
Journal Article
HETEROCYCLES, ISSN 0385-5414, 09/2018, Volume 97, Issue 2, pp. 968 - 997
Lithiation of 1-alkoxyindoles, 3-dimethylaminomethyl- and 3-dimethylaminoethyl-1-methoxyindole occurred regioselectively at the 2-position. The introduction of... 
1-HYDROXYINDOLE DERIVATIVES | LESPEDAMINE | SHORT STEP SYNTHESIS | SYNTHETIC METHOD | CHEMISTRY | CHEMISTRY, ORGANIC | INDOLES
Journal Article
Journal of Natural Products, ISSN 0163-3864, 01/2017, Volume 80, Issue 1, pp. 220 - 224
Journal Article
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 34, pp. 56942 - 56958
Triple negative breast cancer (TNBC) is a highly metastatic cancer among the breast cancer subgroups. A thorny issue for clinical therapy of TNBC is lack of an... 
Oxidative stress | Breast cancer | Sesquiterpene lactone | Paraptosis
Journal Article
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