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Nature Genetics, ISSN 1061-4036, 04/2015, Volume 47, Issue 4, pp. 330 - 337
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2016, Volume 48, Issue 12, pp. 1551 - 1556
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 513, Issue 7519, pp. 512 - 516
Mutations that deregulate Notch1 and Ras/phosphoinositide 3 kinase (PI3K)/Akt signalling are prevalent in T-cell acute lymphoblastic leukaemia (T-ALL), and... 
ACTIVATION | MULTIDISCIPLINARY SCIENCES | ACUTE LYMPHOBLASTIC-LEUKEMIA | FREQUENCY | PTEN | MUTATIONS | CANCER | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - pathology | Clone Cells - drug effects | Diphenylamine - pharmacology | Receptor, Notch1 - chemistry | Male | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Diphenylamine - analogs & derivatives | Receptor, Notch1 - deficiency | Benzamides - therapeutic use | Benzamides - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Genes, ras - genetics | Protein Structure, Tertiary | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Diphenylamine - therapeutic use | Mice, Inbred C57BL | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Receptor, Notch1 - metabolism | Down-Regulation - drug effects | Sulfonamides - pharmacology | Clone Cells - metabolism | Drug Synergism | Indazoles - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Clone Cells - pathology | Signal Transduction - drug effects | Sulfonamides - therapeutic use | Precursor T-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Protein Kinase Inhibitors - therapeutic use | Mice | Protein Kinase Inhibitors - pharmacology | Receptor, Notch1 - genetics | Indazoles - therapeutic use | Drug Resistance, Neoplasm - drug effects | Studies | Rodents | Leukemia | Cloning | Medical prognosis | Mutation | Drug resistance | Gene expression | Drug dosages | Mass spectrometry
Journal Article
Genome Biology, ISSN 1474-7596, 03/2019, Volume 20, Issue 1, pp. 50 - 15
BackgroundSequencing errors are key confounding factors for detecting low-frequency genetic variants that are important for cancer molecular diagnosis,... 
Deep sequencing | Subclonal | Substitution | Detection | Hotspot mutation | Error rate | MUTATIONAL PROCESSES | SIGNATURES | LANDSCAPE | RISK | GENOME | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CLONAL HEMATOPOIESIS | DNA | GENES | GENETICS & HEREDITY | AGE | Datasets | Studies | Genetic variance | Next-generation sequencing | Archives & records | Quality | Software | Genomes | Mutation | Bioinformatics | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2019, Volume 51, Issue 2, pp. 296 - 307
Journal Article
Journal Article