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Journal of Clinical Pharmacology, ISSN 0091-2700, 06/2008, Volume 48, Issue 6, pp. 662 - 670
Predicting clinically significant drug interactions during drug development is a challenge for the pharmaceutical industry and regulatory agencies. Since the... 
P-glycoprotein | Cytochrome P450 enzymes | Pharmacogenetics | Transporter proteins | Induction | Drug interactions | Inhibition | Physiological aspects | Research
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 05/2008, Volume 36, Issue 5, pp. 946 - 954
Journal Article
Journal Article
Journal Article
The induction of cytochrome P450 (CYP) 3A enzymes (human isoform, CYP3A4) is a common cause of serious drug interactions. Recent cloned pregnane X receptor... 
paclitaxel | CYP3A | enzyme induction | Pregnane X Receptor | docetaxel
Dissertation
01/2002, ISBN 9780493680590
The induction of cytochrome P450 (CYP) 3A enzymes (human isoform, CYP3A4) is a common cause of serious drug interactions. Recent cloned pregnane X receptor... 
Oncology | Pharmaceuticals
Dissertation
2007, 1, ISBN 9780849338274
For a drug to exert the desired pharmacological effect, therapeutic concentrations of the drug need to be available at the cellular sites of action. Depending... 
Book Chapter
Journal Article