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by Peters, Marjolein J and Joehanes, Roby and Pilling, Luke C and Schurmann, Claudia and Conneely, Karen N and Powell, Joseph and Reinmaa, Eva and Sutphin, George L and Zhernakova, Alexandra and Schramm, Katharina and Wilson, Yana A and Kobes, Sayuko and Tukiainen, Taru and Ramos, Yolande F and Göring, Harald H. H and Fornage, Myriam and Liu, Yongmei and Gharib, Sina A and Stranger, Barbara E and De Jager, Philip L and Aviv, Abraham and Levy, Daniel and Murabito, Joanne M and Munson, Peter J and Huan, Tianxiao and Hofman, Albert and Uitterlinden, André G and Rivadeneira, Fernando and van Rooij, Jeroen and Stolk, Lisette and Broer, Linda and Verbiest, Michael M. P. J and Jhamai, Mila and Arp, Pascal and Metspalu, Andres and Tserel, Liina and Milani, Lili and Samani, Nilesh J and Peterson, Pärt and Kasela, Silva and Codd, Veryan and Peters, Annette and Ward-Caviness, Cavin K and Herder, Christian and Waldenberger, Melanie and Roden, Michael and Singmann, Paula and Zeilinger, Sonja and Illig, Thomas and Homuth, Georg and Grabe, Hans-Jörgen and Völzke, Henry and Steil, Leif and Kocher, Thomas and Murray, Anna and Melzer, David and Yaghootkar, Hanieh and Bandinelli, Stefania and Moses, Eric K and Kent, Jack W and Curran, Joanne E and Johnson, Matthew P and Williams-Blangero, Sarah and Westra, Harm-Jan and McRae, Allan F and Smith, Jennifer A and Kardia, Sharon L. R and Hovatta, Iiris and Perola, Markus and Ripatti, Samuli and Salomaa, Veikko and Henders, Anjali K and Martin, Nicholas G and Smith, Alicia K and Mehta, Divya and Binder, Elisabeth B and Nylocks, K Maria and Kennedy, Elizabeth M and Klengel, Torsten and Ding, Jingzhong and Suchy-Dicey, Astrid M and Enquobahrie, Daniel A and Brody, Jennifer and Rotter, Jerome I and Chen, Yii-Der I and Houwing-Duistermaat, Jeanine and Kloppenburg, Margreet and Slagboom, P. Eline and Helmer, Quinta and den Hollander, Wouter and Bean, Shannon and Raj, Towfique and Bakhshi, Noman and Wang, Qiao Ping and Oyston, Lisa J and Psaty, Bruce M and Tracy, Russell P and Montgomery, Grant W and Turner, Stephen T and Blangero, John and ... and NABEC/UKBEC Consortium and NABEC UKBEC Consortium
Nature communications, ISSN 2041-1723, 10/2015, Volume 6, Issue 1, pp. 8570 - 8570
Disease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately understood.... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Aging - blood | DNA Methylation | Humans | Transcriptome | European Continental Ancestry Group | Gene Expression Profiling | Biomarkers - blood | Index Medicus
Journal Article
by Seshadri, Sudha and Fitzpatrick, Annette L and Ikram, M. Arfan and DeStefano, Anita L and Gudnason, Vilmundur and Boada, Merce and Bis, Joshua C and Smith, Albert V and Carrasquillo, Minerva M and Lambert, Jean Charles and Harold, Denise and Schrijvers, Elisabeth M. C and Ramirez-Lorca, Reposo and Debette, Stephanie and Longstreth, W. T and Janssens, A. Cecile J. W and Pankratz, V. Shane and Dartigues, Jean François and Hollingworth, Paul and Aspelund, Thor and Hernandez, Isabel and Beiser, Alexa and Kuller, Lewis H and Koudstaal, Peter J and Dickson, Dennis W and Tzourio, Christophe and Abraham, Richard and Antunez, Carmen and Du, Yangchun and Rotter, Jerome I and Aulchenko, Yurii S and Harris, Tamara B and Petersen, Ronald C and Berr, Claudine and Owen, Michael J and Lopez-Arrieta, Jesus and Vardarajan, Badri N and Becker, James T and Rivadeneira, Fernando and Nalls, Michael A and Graff-Radford, Neill R and Campion, Dominique and Auerbach, Sanford and Rice, Kenneth and Hofman, Albert and Jonsson, Palmi V and Schmidt, Helena and Lathrop, Mark and Mosley, Thomas H and Au, Rhoda and Psaty, Bruce M and Uitterlinden, Andre G and Farrer, Lindsay A and Lumley, Thomas and Ruiz, Agustin and Williams, Julie and Amouyel, Philippe and Younkin, Steve G and Wolf, Philip A and Launer, Lenore J and Lopez, Oscar L and van Duijn, Cornelia M and Breteler, Monique M. B and CHARGE, GERAD1, and EADI1 Consortia, for the and CHARGE GERAD1 EADI1 Consortia and EADI1 Consortium and CHARGE Consortium and GERAD1 Consortium
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 05/2010, Volume 303, Issue 18, pp. 1832 - 1840
Journal Article
by N'Diaye, Amidou and Chen, Gary K and Palmer, Cameron D and Ge, Bing and Tayo, Bamidele and Mathias, Rasika A and Ding, Jingzhong and Nalls, Michael A and Adeyemo, Adebowale and Adoue, Véronique and Ambrosone, Christine B and Atwood, Larry and Bandera, Elisa V and Becker, Lewis C and Berndt, Sonja I and Bernstein, Leslie and Blot, William J and Boerwinkle, Eric and Britton, Angela and Casey, Graham and Chanock, Stephen J and Demerath, Ellen and Deming, Sandra L and Diver, W. Ryan and Fox, Caroline and Harris, Tamara B and Hernandez, Dena G and Hu, Jennifer J and Ingles, Sue A and John, Esther M and Johnson, Craig and Keating, Brendan and Kittles, Rick A and Kolonel, Laurence N and Kritchevsky, Stephen B and Marchand, Loic and Lohman, Kurt and Liu, Jiankang and Millikan, Robert C and Murphy, Adam and Musani, Solomon and Neslund-Dudas, Christine and North, Kari E and Nyante, Sarah and Ogunniyi, Adesola and Ostrander, Elaine A and Papanicolaou, George and Patel, Sanjay and Pettaway, Curtis A and Press, Michael F and Redline, Susan and Rodriguez-Gil, Jorge L and Rotimi, Charles and Rybicki, Benjamin A and Salako, Babatunde and Schreiner, Pamela J and Signorello, Lisa B and Singleton, Andrew B and Stanford, Janet L and Stram, Alex H and Stram, Daniel O and Strom, Sara S and Suktitipat, Bhoom and Thun, Michael J and Witte, John S and Yanek, Lisa R and Ziegler, Regina G and Zheng, Wei and Zhu, Xiaofeng and Zmuda, Joseph M and Zonderman, Alan B and Evans, Michele K and Liu, Yongmei and Becker, Diane M and Cooper, Richard S and Pastinen, Tomi and Henderson, Brian E and Hirschhorn, Joel N and Lettre, Guillaume and Haiman, Christopher A
PLoS genetics, ISSN 1553-7390, 10/2011, Volume 7, Issue 10, pp. e1002298 - e1002298
Journal Article
by Renton, Alan E and Majounie, Elisa and Waite, Adrian and Simón-Sánchez, Javier and Rollinson, Sara and Gibbs, J. Raphael and Schymick, Jennifer C and Laaksovirta, Hannu and van Swieten, John C and Myllykangas, Liisa and Kalimo, Hannu and Paetau, Anders and Abramzon, Yevgeniya and Remes, Anne M and Kaganovich, Alice and Scholz, Sonja W and Duckworth, Jamie and Ding, Jinhui and Harmer, Daniel W and Hernandez, Dena G and Johnson, Janel O and Mok, Kin and Ryten, Mina and Trabzuni, Danyah and Guerreiro, Rita J and Orrell, Richard W and Neal, James and Murray, Alex and Pearson, Justin and Jansen, Iris E and Sondervan, David and Seelaar, Harro and Blake, Derek and Young, Kate and Halliwell, Nicola and Callister, Janis Bennion and Toulson, Greg and Richardson, Anna and Gerhard, Alex and Snowden, Julie and Mann, David and Neary, David and Nalls, Michael A and Peuralinna, Terhi and Jansson, Lilja and Isoviita, Veli-Matti and Kaivorinne, Anna-Lotta and Hölttä-Vuori, Maarit and Ikonen, Elina and Sulkava, Raimo and Benatar, Michael and Wuu, Joanne and Chiò, Adriano and Restagno, Gabriella and Borghero, Giuseppe and Sabatelli, Mario and Heckerman, David and Rogaeva, Ekaterina and Zinman, Lorne and Rothstein, Jeffrey D and Sendtner, Michael and Drepper, Carsten and Eichler, Evan E and Alkan, Can and Abdullaev, Ziedulla and Pack, Svetlana D and Dutra, Amalia and Pak, Evgenia and Hardy, John and Singleton, Andrew and Williams, Nigel M and Heutink, Peter and Pickering-Brown, Stuart and Morris, Huw R and Tienari, Pentti J and Traynor, Bryan J and The ITALSGEN Consortium and ITALSGEN Consortium
Neuron (Cambridge, Mass.), ISSN 0896-6273, 10/2011, Volume 72, Issue 2, pp. 257 - 268
Journal Article
by Lesage, Suzanne and Drouet, Valérie and Majounie, Elisa and Deramecourt, Vincent and Jacoupy, Maxime and Nicolas, Aude and Cormier-Dequaire, Florence and Hassoun, Sidi Mohamed and Pujol, Claire and Ciura, Sorana and Erpapazoglou, Zoi and Usenko, Tatiana and Maurage, Claude-Alain and Sahbatou, Mourad and Liebau, Stefan and Ding, Jinhui and Bilgic, Basar and Emre, Murat and Erginel-Unaltuna, Nihan and Guven, Gamze and Tison, François and Tranchant, Christine and Vidailhet, Marie and Corvol, Jean-Christophe and Krack, Paul and Leutenegger, Anne-Louise and Nalls, Michael A and Hernandez, Dena G and Heutink, Peter and Gibbs, J. Raphael and Hardy, John and Wood, Nicholas W and Gasser, Thomas and Durr, Alexandra and Deleuze, Jean-François and Tazir, Meriem and Destée, Alain and Lohmann, Ebba and Kabashi, Edor and Singleton, Andrew and Corti, Olga and Brice, Alexis and Agid, Yves and Anheim, Mathieu and Bonnet, Anne-Marie and Borg, Michel and Broussolle, Emmanuel and Damier, Philippe and Dürr, Alexandra and Durif, Franck and Klebe, Stephan and Martinez, Maria and Pollak, Pierre and Rascol, Olivier and Vérin, Marc and Viallet, François and Corvol, Jean Christophe and Arepalli, Sampath and Barker, Roger A and Ben-Shlomo, Yoav and Berg, Daniela and Bettella, Francesco and Bhatia, Kailash and de Bie, Rob M.A and Biffi, Alessandro and Bloem, Bastiaan R and Bochdanovits, Zoltan and Bonin, Michael and Bras, Jose M and Brockmann, Kathrin and Brooks, Janet and Burn, David J and Charlesworth, Gavin and Chen, Honglei and Chinnery, Patrick F and Chong, Sean and Clarke, Carl E and Cookson, Mark R and Counsell, Carl and Dartigues, Jean-François and Deloukas, Panos and Deuschl, Günther and Dexter, David T and van Dijk, Karin D and Dillman, Allissa and Dong, Jing and Durif, Frank and Edkins, Sarah and Escott-Price, Valentina and Evans, Jonathan R and Foltynie, Thomas and Gao, Jianjun and Gardner, Michelle and Goate, Alison and Gray, Emma and Guerreiro, Rita and Harris, Clare and van Hilten, Jacobus J and Hofman, Albert and Hollenbeck, Albert and ... and the International Parkinson's Disease Genomics Consortium (IPDGC) and French Parkinson's Disease Genetics Study (PDG) and International Parkinson's Disease Genomics Consortium (IPDGC)
American journal of human genetics, ISSN 0002-9297, 03/2016, Volume 98, Issue 3, pp. 500 - 513
Journal Article
Nature genetics, ISSN 1546-1718, 11/2009, Volume 41, Issue 12, pp. 1308 - 1312
Journal Article
by Majounie, Elisa and Renton, Alan E and Mok, Kin and Dopper, Elise GP and Waite, Adrian and Rollinson, Sara and Chiò, Adriano and Restagno, Gabriella and Nicolaou, Nayia and Simon-Sanchez, Javier and van Swieten, John C and Abramzon, Yevgeniya and Johnson, Janel O and Sendtner, Michael and Pamphlett, Roger and Orrell, Richard W and Mead, Simon and Sidle, Katie C and Houlden, Henry and Rohrer, Jonathan D and Morrison, Karen E and Pall, Hardev and Talbot, Kevin and Ansorge, Olaf and Hernandez, Dena G and Arepalli, Sampath and Sabatelli, Mario and Mora, Gabriele and Corbo, Massimo and Giannini, Fabio and Calvo, Andrea and Englund, Elisabet and Borghero, Giuseppe and Floris, Gian Luca and Remes, Anne M and Laaksovirta, Hannu and McCluskey, Leo and Trojanowski, John Q and Van Deerlin, Vivianna M and Schellenberg, Gerard D and Nalls, Michael A and Drory, Vivian E and Lu, Chin-Song and Yeh, Tu-Hsueh and Ishiura, Hiroyuki and Takahashi, Yuji and Tsuji, Shoji and Le Ber, Isabelle and Brice, Alexis and Drepper, Carsten and Williams, Nigel and Kirby, Janine and Shaw, Pamela and Hardy, John and Tienari, Pentti J and Heutink, Peter and Morris, Huw R and Pickering-Brown, Stuart and Traynor, Bryan J and The Chromosome 9-ALS/FTD Consortium and The ITALSGEN Consortium and The French research network on FTLD/FTLD/ALS and Chromosome 9-ALS FTD Consortium and French Res Network FTLD FTLD ALS and ITALSGEN Consortium and French research network on FTLD/FTLD/ALS and Chromosome 9-ALS/FTD Consortium
Lancet neurology, ISSN 1474-4422, 04/2012, Volume 11, Issue 4, pp. 323 - 330
Summary Background We aimed to accurately estimate the frequency of a hexanucleotide repeat expansion in C9orf72 that has been associated with a large... 
Neurology | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Frontotemporal Dementia - genetics | Cross-Sectional Studies | DNA Repeat Expansion - genetics | Amyotrophic Lateral Sclerosis - genetics | Humans | Middle Aged | Child, Preschool | Genotype | Male | Genetic Loci | Open Reading Frames - genetics | Young Adult | Chromosomes, Human, Pair 9 - genetics | Adolescent | Age of Onset | Aged, 80 and over | Adult | Female | Aged | Child | Cohort Studies | Medical research | Medical colleges | Care and treatment | Nervous system diseases | Neurosciences | Molecular genetics | Oncology, Experimental | Questions and answers | Amyotrophic lateral sclerosis | Research | Medicine, Experimental | Agriculture | Physicians (General practice) | Alzheimer's disease | Dementia | Cancer | Biomedical engineering | Index Medicus | Haplotypes | Polymerase chain reaction | Neurodegenerative diseases | Ethnic groups | Data processing | Mutation | Frontotemporal dementia | Genetic counselling | Islands | Age | Toll-Like Receptor 4 | Open Reading Frames | Adaptor Proteins, Vesicular Transport | Lipopolysaccharides | Life Sciences | DNA Repeat Expansion | Interferon Regulatory Factor-3 | Transfection | Amyotrophic Lateral Sclerosis | RNA Interference | HEK293 Cells | Membrane Glycoproteins | Vesicular Transport Proteins | Protein Structure, Tertiary | Cell Line | Chemokine CCL5 | Frontotemporal Dementia | Signal Transduction | Myeloid Differentiation Factor 88 | Chromosomes, Human, Pair 9 | Protein Transport | Adaptor Proteins, Signal Transducing | Santé publique et épidémiologie | RNA, Small Interfering | Endosomes | Neurologi | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap
Journal Article