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1. Full Text CSIG-27. PATIENT-DERIVED CELL ORIGINATED SECRETOME ANALYSIS IDENTIFIES MIDKINE AS A POTENT THERAPEUTIC TARGET IN GLIOBLASTOMA
by Shin, Hyemi and Sa, Jason and Nam, Do-Hyun
Neuro-Oncology, ISSN 1522-8517, 11/2017, Volume 19, Issue suppl_6, pp. vi55 - vi55
Glioblastoma multiforme (GBM) is the most malignant form of central nervous system tumor. Growth factors that are included as a supplement in a conditioned... 
Abstracts
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2. Full Text GENT-09. QUANTITATIVE IMAGING BIOMARKER FOR PREDICTING GENOMIC PROFILES IN GLIOBLASTOMA
by Nam, Do-Hyun and Seol, Ho Jun
Neuro-Oncology, ISSN 1522-8517, 11/2016, Volume 18, Issue suppl_6, pp. vi75 - vi75
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3. Full Text Correlation Tracking with Correcting and Adaptive Update Strategy
by Peng, Shao-Hu and Nam, Hyun-Do
Journal of Electrical Engineering & Technology, ISSN 1975-0102, 9/2019, Volume 14, Issue 5, pp. 2181 - 2190
Object tracking plays an important role in the research field of computer vision. Correlation filter (CF) based tracking algorithms have shown remarkable... 
Power Electronics, Electrical Machines and Networks | Engineering | Computer vision | Correlation filter | Electronics and Microelectronics, Instrumentation | Object tracking | Four-level classifier | Electrical Engineering | Tracking learning detection
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4. Full Text SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma
by Son, Myung Jin and Woolard, Kevin and Nam, Do-Hyun and Lee, Jeongwu and Fine, Howard A
Cell Stem Cell, ISSN 1934-5909, 05/2009, Volume 4, Issue 5, pp. 440 - 452
CD133+ populations of human glioblastoma multiforme (GBM) cells are reportedly enriched for tumor stem cells (TSCs) or tumor-initiating cells (TICs).... 
STEMCELL | PROGENITOR CELLS | NERVOUS-SYSTEM | PROTEIN | GLIOMA | GROWTH | IDENTIFICATION | BRAIN | CANCER STEM-CELLS | CD133 | ANTIGEN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neoplastic Stem Cells - cytology | Cell Proliferation | Humans | Male | Lewis X Antigen - metabolism | Mice, SCID | Cell Lineage | Animals | Flow Cytometry | Cell Cycle | Neoplastic Stem Cells - metabolism | Female | Glioblastoma - metabolism | Cell Differentiation | Mice | Tumor Cells, Cultured | Index Medicus
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5. Full Text Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
by Kim, Misuk and Kim, Hong and Kim, Eunhee and Woo, Dong-Hun and Shin, Jihye and Shin, Yongjae and Chang, Nakho and Oh, Young Taek and Rheey, Jingeun and Nakano, Ichiro and Lee, Cheolju and Lee, Jeongwu and Joo, Kyeung Min and Rich, Jeremy N and Nam, Do-Hyun
Cancer Cell, ISSN 1535-6108, 06/2013, Volume 23, Issue 6, pp. 839 - 852
Glioblastoma multiforme (GBM) displays cellular hierarchies harboring a subpopulation of stem-like cells (GSCs). Enhancer of Zeste Homolog 2 (EZH2), the lysine... 
CANCER-CELLS | DEVELOPMENTAL REGULATORS | ONCOLOGY | PROSTATE-CANCER | GROUP PROTEIN EZH2 | POLYCOMB COMPLEX | NF-KAPPA-B | HISTONE METHYLTRANSFERASE | MEDIATED REPRESSION | TUMOR-INITIATING CELLS | BRAIN-TUMORS | CELL BIOLOGY | Phosphorylation | Signal Transduction | Humans | Gene Silencing | Transplantation, Heterologous | Polycomb-Group Proteins | Enhancer of Zeste Homolog 2 Protein | Animals | Cell Transformation, Neoplastic | Glioblastoma - pathology | Polycomb Repressive Complex 2 - physiology | Glioblastoma - metabolism | Mice | Tumor Cells, Cultured | Methylation | Polycomb Repressive Complex 2 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - metabolism | Health aspects | Glioblastoma multiforme | Transferases | Stem cells | Index Medicus
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6. Full Text TMIC-41. APOPTOTIC CELLS PROMOTE MALIGNANCY OF SURVIVING GLIOBLASTOMA CELLS BY INTERCELLULAR TRANSFER OF SPLICING FACTORS
by Pavlyukov, Marat and Bastola, Soniya and Yu, Hai and Shender, Victoria O and Anufrieva, Ksenia and Nam, Do-Hyun and Nakano, Ichiro
Neuro-Oncology, ISSN 1522-8517, 11/2018, Volume 20, Issue suppl_6, pp. vi265 - vi265
Abstract Because of the pressure of rapid expansion of tumor, intratumoral microenvironment becomes inevitably harsh, resulting in abundant apoptotic tumor... 
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7. Full Text Outcome of three-fraction gamma knife radiosurgery for brain metastases according to fractionation scheme: preliminary results
by Chiman Jeon and Kyung Rae Cho and Jung Won Choi and Doo-Sik Kong and Ho Jun Seol and Do-Hyun Nam and Jung-Il Lee
Journal of Neuro - Oncology, ISSN 0167-594X, 08/2019, pp. 1 - 10
Purpose The optimal interfraction intervals for fractionated radiosurgery has yet to be established. We investigated the outcome of fractionated gamma knife... 
Fractionation | Metastasis | Multivariate analysis | Metastases | Index Medicus
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8. Full Text Clonal evolution of glioblastoma under therapy
by Wang, Jiguang and Cazzato, Emanuela and Ladewig, Erik and Frattini, Veronique and Rosenbloom, Daniel I S and Zairis, Sakellarios and Abate, Francesco and Liu, Zhaoqi and Elliott, Oliver and Shin, Yong-Jae and Lee, Jin-Ku and Lee, In-Hee and Park, Woong-Yang and Eoli, Marica and Blumberg, Andrew J and Lasorella, Anna and Nam, Do-Hyun and Finocchiaro, Gaetano and Iavarone, Antonio and Rabadan, Raul
Nature Genetics, ISSN 1061-4036, 07/2016, Volume 48, Issue 7, pp. 768 - 776
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. To better understand how GBM evolves, we analyzed longitudinal genomic and... 
GENE FUSIONS | TGF-BETA | CANCER GENOMICS | LANDSCAPE | GLIOMA | GENETICS & HEREDITY | GENOMIC ALTERATIONS | MSH6 MUTATIONS | SEQUENCING DATA | BRAIN-TUMORS | TEMOZOLOMIDE | Cell Proliferation | Dacarbazine - therapeutic use | Genomics | Humans | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Transcriptome | Neoplasm Recurrence, Local - drug therapy | Clonal Evolution - genetics | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Glioblastoma - genetics | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Survival Rate | Brain Neoplasms - drug therapy | Mutation - genetics | Antineoplastic Agents, Alkylating - therapeutic use | Latent TGF-beta Binding Proteins - genetics | DNA Modification Methylases - genetics | Transforming Growth Factor beta - genetics | Glioblastoma - pathology | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Glioblastoma - drug therapy | Longitudinal Studies | Molecular targeted therapy | Care and treatment | Gene mutations | Development and progression | Genetic aspects | Genetic transcription | Glioblastoma multiforme | Health aspects | Methods | Brain cancer | Genomes | Gene expression | Cancer therapies | Studies | Archives & records | DNA methylation | Mathematical models | Mutation | Deoxyribonucleic acid--DNA | Tumors | Cancer | Index Medicus
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9. Full Text Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre, randomised, open-label, phase 3 trial
by Stupp, Roger, Prof and Hegi, Monika E, PhD and Gorlia, Thierry, PhD and Erridge, Sara C, MD and Perry, James, MD and Hong, Yong-Kil, Prof and Aldape, Kenneth D, Prof and Lhermitte, Benoit, MD and Pietsch, Torsten, Prof and Grujicic, Danica, Prof and Steinbach, Joachim Peter, Prof and Wick, Wolfgang, Prof and Tarnawski, Rafał, Prof and Nam, Do-Hyun, Prof and Hau, Peter, Prof and Weyerbrock, Astrid, MD and Taphoorn, Martin J B, Prof and Shen, Chiung-Chyi, MD and Rao, Nalini, MD and Thurzo, László, MD and Herrlinger, Ulrich, MD and Gupta, Tejpal, MD and Kortmann, Rolf-Dieter, Prof and Adamska, Krystyna, MD and McBain, Catherine, MD and Brandes, Alba A, MD and Tonn, Joerg Christian, Prof and Schnell, Oliver, MD and Wiegel, Thomas, Prof and Kim, Chae-Yong, MD and Nabors, Louis Burt, MD and Reardon, David A, MD and van den Bent, Martin J, Prof and Hicking, Christine, MSc and Markivskyy, Andriy, MD and Picard, Martin, PhD and Weller, Michael, Prof and Canadian Brain Tumor Consortium and European Org Res Treatment Canc and CENTRIC Study Team and European Organisation for Research and Treatment of Cancer (EORTC) and CENTRIC study team
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 10, pp. 1100 - 1108
Summary Background Cilengitide is a selective αvβ3 and αvβ5 integrin inhibitor. Data from phase 2 trials suggest that it has antitumour activity as a single... 
Hematology, Oncology and Palliative Medicine | MALIGNANT GLIOMA | UNITED-STATES | CLINICAL-TRIAL | ONCOLOGY | BEVACIZUMAB | RECURRENT GLIOBLASTOMA | INTEGRIN ALPHA(V)BETA | RADIOTHERAPY | EXPRESSION | BRAIN | TEMOZOLOMIDE | Confidence Intervals | Early Detection of Cancer - methods | Follow-Up Studies | Snake Venoms - therapeutic use | Dacarbazine - therapeutic use | Humans | Middle Aged | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Male | Reference Values | Patient Selection | Dose-Response Relationship, Drug | Glioblastoma - genetics | Neoplasm Invasiveness - pathology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Female | Brain Neoplasms - mortality | Promoter Regions, Genetic | Drug Administration Schedule | Kaplan-Meier Estimate | Proportional Hazards Models | Brain Neoplasms - genetics | Treatment Outcome | Brain Neoplasms - drug therapy | Disease-Free Survival | DNA Modification Methylases - genetics | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Glioblastoma - pathology | Survival Analysis | Aged | Glioblastoma - drug therapy | Neoplasm Staging | Glioblastoma - mortality | Medicine, Experimental | Medical research | Care and treatment | Glioblastoma multiforme | Integrins | Index Medicus
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10. Full Text Jageum-Jung improves 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice and suppresses pro-inflammatory chemokine production by inhibiting TNF-[alpha]/IFN-[gamma]-induced STAT-1 and NF[kappa]B signaling in HaCaT cells
by Yang, Ju-Hye and Do, Hyun Ju and Lee, Esther and Yim, Nam-Hui and Cho, Won-Kyung and Park, Kwang-Il and Ma, Jin Yeul
Journal of Ethnopharmacology, ISSN 0378-8741, 07/2018, Volume 221, p. 48
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.jep.2018.04.016... 
RNA | Tumor necrosis factor | Atopic dermatitis | Medicine, Botanic | Medicine, Herbal | Skin | Interferon
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11. Full Text Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment
by Wang, Qianghu and Wang, Guocan and Hu, Baoli and Hu, Xin and Hu, Jian and Kim, Hoon and Squatrito, Massimo and Scarpace, Lisa and deCarvalho, Ana C and Lyu, Sali and Li, Pengping and Li, Yan and Barthel, Floris and Cho, Hee Jin and Lin, Yu-Hsi and Satani, Nikunj and Martinez-Ledesma, Emmanuel and Zheng, Siyuan and Chang, Edward and Sauvé, Charles-Etienne Gabriel and Olar, Adriana and Lan, Zheng D and Finocchiaro, Gaetano and Phillips, Joanna J and Berger, Mitchel S and Gabrusiewicz, Konrad R and Eskilsson, Eskil and Mikkelsen, Tom and DePinho, Ronald A and Muller, Florian and Heimberger, Amy B and Sulman, Erik P and Nam, Do-Hyun and Verhaak, Roel G.W
Cancer Cell, ISSN 1535-6108, 07/2017, Volume 32, Issue 1, pp. 42 - 56.e6
We leveraged wild-type glioblastomas, derivative neurospheres, and single-cell gene expression profiles to define three tumor-intrinsic transcriptional... 
glioblastoma | proneural to mesenchymal transition | disease recurrence | mesenchymal subtype | immune cells | tumor evolution | tumor microenvironment | macrophages/microglia | HETEROGENEITY | GLIOBLASTOMA | ONCOLOGY | MACROPHAGES | IDH1 | QUANTIFICATION | CELL-CYCLE | MUTATIONS | DIFFERENTIATION | BLOCKADE | REVEALS | CELL BIOLOGY | Tumor Microenvironment - immunology | Recurrence | Phenotype | Glioblastoma - genetics | Glioblastoma - immunology | Glioblastoma - pathology | Humans | Gene Expression Regulation, Neoplastic | Survival Analysis | T-Lymphocytes - immunology | Gene Expression Profiling | Relapse | Gliomas | Analysis | Genes | Stem cells | Genetic aspects | Gene expression | Cancer | Diseases | Index Medicus
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12. Full Text Automated stitching of microscope images of fluorescence in cells with minimal overlap
by Seo, Ji-Hyun and Yang, Sejung and Kang, Mi-Sun and Her, Nam-Gu and Nam, Do-Hyun and Choi, Jang-Hwan and Kim, Myoung Hee
Micron, ISSN 0968-4328, 11/2019, Volume 126, pp. 102718 - 102718
The morphology of tumor cells is highly related to their phenotype and activity. To verify the drug response of a brain tumor patient, fluorescence microscope... 
High-content screening | Fluorescence microscope images | Brain tumor cell | Tile scan | Image stitching | Index Medicus
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13. Full Text Development of a T1 contrast agent for magnetic resonance imaging using MnO nanoparticles
by Na, Hyon Bin and Lee, Jung Hee and An, Kwangjin and Park, Yong Il and Park, Mihyun and Lee, In Su and Nam, Do-Hyun and Kim, Sung Tae and Kim, Seung-Hoon and Kim, Sang-Wook and Lim, Keun-Ho and Kim, Ki-Soo and Kim, Sun-Ok and Hyeon, Taeghwan
Angewandte Chemie - International Edition, ISSN 1433-7851, 2007, Volume 46, Issue 28, pp. 5397 - 5401
Nanoparticles | Contrast agents | Imaging agents | Magnetic resonance imaging | Manganese | Microscopy, Electron, Transmission | Humans | Metal Nanoparticles - chemistry | Oxides - chemistry | Brain - drug effects | Magnetic Resonance Imaging | Contrast Media - pharmacology | Animals | Cell Line, Tumor | Contrast Media - chemistry | Mice | Drug Evaluation, Preclinical | Manganese Compounds - chemistry | Metal Nanoparticles - ultrastructure | Index Medicus
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14. Full Text Synthesis and anticancer activity of benzoselenophene and heteroaromatic derivatives of 1,2,9,9a-tetrahydrocyclopropa[c]benzo[e]indol-4-one (CBI)Electronic supplementary information (ESI) available. See DOI: 10.1039/c6ob02729f
by Mhetre, Amol B and Lee, Hangeun and Yang, Heekyoung and Lee, Kyoungmin and Nam, Do-Hyun and Lim, Dongyeol
ISSN 1477-0520, 2/2017, Volume 15, Issue 5, pp. 1198 - 128
The current study reports the synthesis of different derivatives of benzoselenophene analogs as well as a diverse series of compounds ( 14a-p , 15 and 16 )... 
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15. Full Text A robust crack filter based on local gray level variation and multiscale analysis for automatic crack detection in X-ray images
by Peng, Shao-Hu and Nam, Hyun-Do
Journal of Electrical Engineering and Technology, ISSN 1975-0102, 07/2016, Volume 11, Issue 4, pp. 1037 - 1043
Crack filter | Multiscale analysis | Gray level variation | X-ray image | Crack detection
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16. Full Text Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells
by Kim, Kyu-Tae and Lee, Hye Won and Lee, Hae-Ock and Kim, Sang Cheol and Seo, Yun Jee and Chung, Woosung and Eum, Hye Hyeon and Nam, Do-Hyun and Kim, Junhyong and Joo, Kyeung Min and Park, Woong-Yang
Genome Biology, ISSN 1474-7596, 06/2015, Volume 16, Issue 1, pp. 127 - 127
Background: Intra-tumoral genetic and functional heterogeneity correlates with cancer clinical prognoses. However, the mechanisms by which intra-tumoral... 
CANCER PATIENTS | SURVIVAL | EVOLUTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | SOMATIC POINT MUTATIONS | GENETICS & HEREDITY | CONSEQUENCES | GENETIC-HETEROGENEITY | KRAS | SIGNATURE | SEQ | EGFR | Lung Neoplasms - genetics | Lung Neoplasms - drug therapy | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Adenocarcinoma - drug therapy | Genetic Heterogeneity | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Phenotype | Adenocarcinoma - metabolism | Animals | Sequence Analysis, RNA | RNA, Messenger - chemistry | Adenocarcinoma - genetics | Mice | Tumor Cells, Cultured | Single-Cell Analysis | Adenocarcinoma | Tumor cells | Lung | Lung cancer | Genomes | Gene expression | Drug resistance | Kinases | Cancer therapies | Patients | Xenografts | Mutation | Bioinformatics | Tumors | Index Medicus | Research
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17. Full Text Volumetric changes of intracranial metastases during the course of fractionated stereotactic radiosurgery and significance of adaptive planning
by Lee, Min Ho and Kim, Kyung Hwan and Cho, Kyung Rae and Choi, Jung Won and Kong, Doo-Sik and Seol, Ho Jun and Nam, Do-Hyun and Lee, Jung-Il
Journal of neurosurgery, ISSN 0022-3085, 05/2019, pp. 1 - 6
OBJECTIVEFractionated Gamma Knife surgery (FGKS) has recently been used to treat large brain metastases. However, little is known about specific volume changes... 
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