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Environmental Health Perspectives, ISSN 0091-6765, 8/2009, Volume 117, Issue 8, pp. 1210 - 1218
Background: An increasing number of studies are reporting the existence of polybrominated diphenyl ethers (PBDEs) and their hydroxylated (HO) and methoxylated... 
Hormone receptors | Hormone metabolism | Receptors | Dose response relationship | Cellular metabolism | Halogenated diphenyl ethers | Plasmids | Congeners | Flame retardants | Research | Ethers | Estrogen receptor | Androgen receptor | Glucocorticoid receptor | Reporter gene assay | Brominated diphenyl ether | Thyroid hormone receptor | Chinese hamster ovary cells | glucocorticoid receptor | ESTROGEN-RECEPTORS | estrogen receptor | THYROID-HORMONE | ALPHA | brominated diphenyl ether | reporter gene assay | BETA | ENVIRONMENTAL SCIENCES | IN-VITRO | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | androgen receptor | thyroid hormone receptor | BROMINATED FLAME RETARDANTS | REPORTER GENE ASSAYS | 200 PESTICIDES | TOXICOLOGY | EXPOSURE | Androgen Receptor Antagonists | Cricetinae | Receptors, Glucocorticoid - antagonists & inhibitors | Cricetulus | Humans | Thyroid Hormone Receptors beta - antagonists & inhibitors | Estrogen Receptor alpha - antagonists & inhibitors | Thyroid Hormone Receptors alpha - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - agonists | Halogenated Diphenyl Ethers - chemistry | Receptors, Glucocorticoid - agonists | Halogenated Diphenyl Ethers - metabolism | Androgens | Animals | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Thyroid Hormone Receptors beta - agonists | Molecular Structure | Thyroid Hormone Receptors alpha - agonists | Estrogen Receptor beta - antagonists & inhibitors | CHO Cells | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Metabolites | Health aspects | Polybrominated biphenyls | Index Medicus
Journal Article
Journal Article
Molecules, ISSN 1420-3049, 05/2017, Volume 22, Issue 5, p. 830
An acetaminophen (APAP) overdose can cause hepatotoxicity and lead to fatal liver damage. The hepatoprotective effects of tormentic acid (TA) on acetaminophen... 
Hepatoprotective | Reactive oxygen species | Acetaminophen | HO-1 (heme oxygenase-1) | Tormentic acid | Mapk; NF-kB | Antioxidation | Anti-inflammation | ANTRODIA-CAMPHORATA | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | anti-inflammation | tormentic acid | CHEMISTRY, MULTIDISCIPLINARY | hepatoprotective | acetaminophen | NF-kappa B | INHIBITION | LIVER-INJURY | HEPATIC-FAILURE | reactive oxygen species | THUNB. LINDL. LEAF | NITRIC-OXIDE | TRITERPENE ACIDS | antioxidation | mapk | NF-KAPPA-B | MOLECULAR-MECHANISMS | Acetaminophen - adverse effects | Tumor Necrosis Factor-alpha - metabolism | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Triterpenes - pharmacology | Cholesterol - blood | Tumor Necrosis Factor-alpha - genetics | Male | Alanine Transaminase - blood | Interleukin-1beta - genetics | Liver - drug effects | Cyclooxygenase 2 - genetics | Interleukin-1beta - metabolism | Protective Agents - pharmacology | Eriobotrya - chemistry | Chemical and Drug Induced Liver Injury - pathology | Interleukin-6 - metabolism | Superoxide Dismutase - metabolism | Chemical and Drug Induced Liver Injury - prevention & control | Glutathione Peroxidase - metabolism | Interleukin-6 - genetics | Catalase - genetics | Cells, Cultured | Injections, Intraperitoneal | Protective Agents - isolation & purification | Glutathione Peroxidase - genetics | Catalase - metabolism | Bilirubin - blood | Reactive Oxygen Species - antagonists & inhibitors | Animals | Aspartate Aminotransferases - blood | Nitric Oxide Synthase Type II - genetics | Chemical and Drug Induced Liver Injury - metabolism | Cyclooxygenase 2 - metabolism | Triglycerides - blood | Triterpenes - isolation & purification | Mice | Nitric Oxide - metabolism | Nitric Oxide Synthase Type II - metabolism | Oxidative stress | Liver | Interleukin | Activation | Bilirubin | Kinases | Tissues | Prostaglandin endoperoxide synthase | Interleukin 6 | Elevation | Alterations | Analgesics | Catalase | Rodents | Heme | Attenuation | Tumor necrosis factor-TNF | Peroxidase | Peroxides | Inhibition | Pretreatment | Thiobarbituric acid | Damage | Hepatotoxicity | Injuries | Glutathione | Glutathione peroxidase | NF-κB protein | Oxygen | Alanine | Heme oxygenase (decyclizing) | MAP kinase | Cultures | Sod | Inflammation | Fatal | Cholesterol | Injury prevention | Nitric oxide | Alanine transaminase | Aspartate aminotransferase | Overdose | Cyclooxygenase-2 | Index Medicus | NF-κB
Journal Article
Tetrahedron, ISSN 0040-4020, 10/2014, Volume 70, Issue 41, pp. 7439 - 7444
A modified method for the synthesis of pyrazolo[3,4- ]pyrrolo[3,4- ]pyridine was developed through an Aza-Diels–Alder reaction of pyrazoylimines with... 
Pyrazolopyrrolopyridines | Aza-Diels–Alder reaction | Pyrazoylimines | Leaving group effect | Aza-Diels-Alder reaction | CHEMISTRY, ORGANIC | Cytokinins | Alkaloids | Pyridine | Analysis | Resveratrol | Furans | Diels-Alder reaction
Journal Article
Journal of Applied Toxicology, ISSN 0260-437X, 09/2017, Volume 37, Issue 9, pp. 1030 - 1035
Many concerns have been expressed regarding the possible adverse effects of thyroid hormone‐disrupting chemicals in the environment. The disruption of thyroid... 
thyroid hormones, brominated flame retardant, hepatic gene expression | neonatal exposure | endocrine disruptors | METABOLITES | brominated flame retardant | RECEPTOR | MECHANISMS | HYPERTHYROIDISM | POLYBROMINATED DIPHENYL ETHERS | thyroid hormones | ENDOCRINE DISRUPTERS | hepatic gene expression | FLAME RETARDANTS | MICE | TOXICOLOGY | EXPOSURE | Receptors, Odorant - metabolism | Dioxygenases - metabolism | Rats, Inbred F344 | Male | Mitochondrial Proteins - genetics | RNA, Messenger - metabolism | Organic Anion Transporters, Sodium-Dependent - genetics | Halogenated Diphenyl Ethers - toxicity | Liver - drug effects | Mitochondrial Proteins - metabolism | Thyroid Gland - drug effects | Triiodothyronine - pharmacology | Animals, Newborn | Liver - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Rats | Symporters - metabolism | Endocrine Disruptors - toxicity | Triiodothyronine - blood | Animals | Dioxygenases - genetics | Symporters - genetics | Receptors, Odorant - genetics | Thyroid Gland - metabolism | Organic Anion Transporters, Sodium-Dependent - metabolism | Genetic research | Thyroid hormones | Gene expression | Genes | Chemicals | Endocrine disruptors | Neonates | Liver | Disorders | Homeostasis | Thyroid gland | Hormones | Tissues | Rodents | Triiodothyronine | Age | Thyroid | Diphenyl ether | Markers | Exposure | Studies | Side effects | Polybrominated diphenyl ethers | DNA microarrays | Disruption | Differentiation | Index Medicus
Journal Article
Journal of Heterocyclic Chemistry, ISSN 0022-152X, 05/2015, Volume 52, Issue 3, pp. 880 - 887
The reactions of nine N ‐(pyrido[3′,2′:4,5]thieno[3,2‐ d ]pyrimidin‐4‐yl)amidines ( 3 ) with hydroxylamine hydrochloride produced new cyclization products.... 
CHEMISTRY, ORGANIC | N-(QUINAZOLIN-4-YL)AMIDINE DERIVATIVES
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 01/2015, Volume 282, Issue 2, pp. 119 - 128
Benzophenone-3 (2-hydroxy-4-methoxybenzophenone; BP-3) is widely used as sunscreen for protection of human skin and hair from damage by ultraviolet (UV)... 
Anti-androgenic activity | Metabolic activation | In vitro metabolism | Benzophenone-3 | Ultraviolet absorber | Estrogenic activity | UNITED-STATES | ANDROGEN RECEPTOR | SAFETY EVALUATION | IN-VITRO | HAMSTER OVARY CELLS | CHEMICALS | UTEROTROPHIC ASSAY | ESTROGEN-RECEPTOR-ALPHA | SUNSCREENS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | DERIVATIVES | Cricetinae | Endocrine Disruptors - metabolism | Cricetulus | Androgen Antagonists - metabolism | Humans | Microsomes, Liver - metabolism | Androgen Antagonists - pharmacology | Benzophenones - pharmacology | Cytochrome P-450 Enzyme System - metabolism | Rats | Sunscreening Agents - metabolism | Rats, Sprague-Dawley | Benzophenones - metabolism | Estrogens, Non-Steroidal - metabolism | Animals | Endocrine Disruptors - pharmacology | Biotransformation | beta-Galactosidase - metabolism | Enzyme Induction - drug effects | Sunscreening Agents - pharmacology | Estrogens, Non-Steroidal - pharmacology | In Vitro Techniques | CHO Cells | Physiological aspects | Metabolites | Liver | Estrogen | Cytochrome P-450 | Index Medicus | HUMAN POPULATIONS | DEXAMETHASONE | HAIR | ULTRAVIOLET RADIATION | 3-METHYLCHOLANTHRENE | FILTERS | RATS | COMPARATIVE EVALUATIONS | INCUBATION | PHENOBARBITAL | 60 APPLIED LIFE SCIENCES | CHO CELLS | IN VITRO | MICROSOMES | ESTRADIOL | LIVER | BENZOPHENONE | ANDROGENS
Journal Article
Journal Article