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1. Full Text The rothman index is associated with postdischarge adverse events after hip fracture surgery in geriatric patients
by McLynn, Ryan P and Ottesen, Taylor D and Ondeck, Nathaniel T and Cui, Jonathan J and Rubin, Lee E and Grauer, Jonathan N
Clinical Orthopaedics and Related Research, ISSN 0009-921X, 05/2018, Volume 476, Issue 5, pp. 997 - 1006
BackgroundThe Rothman Index is a comprehensive measure of overall patient status in the inpatient setting already in use at many medical centers. It ranges... 
FEMORAL-NECK FRACTURES | UNITED-STATES | MORTALITY | SURGERY | ELECTRONIC MEDICAL-RECORD | HOSPITAL READMISSION | MANAGEMENT | PREDICTORS | FUNCTIONAL STATUS | ORTHOPEDICS | CURVES | COMORBIDITY | Clinical Research | 0070
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2. Full Text The Rothman Index as a predictor of postdischarge adverse events after elective spine surgery
by McLynn, Ryan P and Ondeck, Nathaniel T and Cui, Jonathan J and Swanson, David R and Shultz, Blake N and Bovonratwet, Patawut and Grauer, Jonathan N
The Spine Journal, ISSN 1529-9430, 07/2018, Volume 18, Issue 7, pp. 1149 - 1156
The Rothman Index (RI) is a comprehensive rating of overall patient condition in the hospital setting. It is used at many medical centers and calculated based... 
Rothman Index | Adverse event | Hospital discharge | Readmission | Elective | Spine surgery | FUSION | READMISSIONS | ADULTS | TRENDS | REFORM | CARE | CLINICAL NEUROLOGY | ELECTRONIC MEDICAL-RECORD | IMPACT | EXPENDITURES | ORTHOPEDICS | HEALTH-STATUS | Patient Readmission | Humans | Middle Aged | Elective Surgical Procedures - adverse effects | Patient Discharge | Female | Male | Aged | Postoperative Complications - epidemiology | Spine - surgery | Medicine, Experimental | Medical records | Medical research | Medical colleges | Mortality | Analysis
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3. Full Text International Patterns and Trends in Thyroid Cancer Incidence, 1973–2002
by Briseis A. Kilfoy and Tongzhang Zheng and Theodore R. Holford and Xuesong Han and Mary H. Ward and Andreas Sjodin and Yaqun Zhang and Yana Bai and Cairong Zhu and Grace L. Guo and Nathaniel Rothman and Yawei Zhang
Cancer Causes & Control, ISSN 0957-5243, 7/2009, Volume 20, Issue 5, pp. 525 - 531
During the past several decades, an increasing incidence of thyroid cancer has been reported in many parts of the world. To date, no study has compared the... 
Thyroid cancer | Halogenated diphenyl ethers | Prophets | Mortality | Population dynamics | Continents | Papillae | Population trends | Population growth rate | Iodine | Biomedicine | Hematology | Papillary thyroid cancer | Oncology | Cancer Research | International trends | Public Health/Gesundheitswesen | Epidemiology | Biomedicine general | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | HORMONAL FACTORS | ONCOLOGY | REPRODUCTIVE FACTORS | BIRTH COHORT | POLYCHLORINATED-BIPHENYLS | Africa - epidemiology | Asia - epidemiology | Global Health | Carcinoma, Papillary - epidemiology | Humans | Thyroid Neoplasms - epidemiology | Europe - epidemiology | Female | Male | Registries | Incidence | International aspects | Distribution
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4. Full Text Occupational Benzene Exposure and the Risk of Lymphoma Subtypes: A Meta-analysis of Cohort Studies Incorporating Three Study Quality Dimensions
by Jelle Vlaanderen and Qing Lan and Hans Kromhout and Nathaniel Rothman and Roel Vermeulen
Environmental Health Perspectives, ISSN 0091-6765, 2/2011, Volume 119, Issue 2, pp. 159 - 167
Background: The use of occupational cohort studies to assess the association of benzene and lymphoma is complicated by problems with exposure... 
Oil industry | Case control studies | Myeloid leukemia | Mortality | Cohort studies | Significance level | Review | Non Hodgkin lymphoma | Lymphoma | Epidemiology | Petroleum | Chronic lymphocytic leukemia | Non-hodgkin lymphoma | Benzene | Leukemia | Multiple myeloma | Acute lymphocytic leukemia | Occupational exposure | Hodgkin lymphoma | Meta-analysis | MULTIPLE-MYELOMA | UNITED-STATES | leukemia | multiple myeloma | meta-analysis | OIL REFINERY WORKERS | FOLLOW-UP | non-Hodgkin lymphoma | occupational exposure | HEMATOLOGIC NEOPLASMS | benzene | PETROLEUM DISTRIBUTION WORKERS | DOSE-RELATED INCIDENCE | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | chronic lymphocytic leukemia | INDUSTRY WIDE MORTALITY | acute lymphocytic leukemia | NON-HODGKIN-LYMPHOMA | TOXICOLOGY | INTERLYMPH-CONSORTIUM | Lymphoma, Non-Hodgkin - chemically induced | Occupational Exposure - adverse effects | Humans | Risk Factors | Multiple Myeloma - chemically induced | Hodgkin Disease - chemically induced | Leukemia, Lymphocytic, Chronic, B-Cell - chemically induced | Leukemia, Myeloid, Acute - chemically induced | Occupational health and safety | Lymphomas | Health aspects | Risk factors | Heterogeneity | Classification | Delineation | Occupational | Risk | Assessments | Stratification | Leukemias
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5. Full Text Counterpoint: Bias from Population Stratification Is Not a Major Threat to the Validity of Conclusions from Epidemiological Studies of Common Polymorphisms and Cancer
by Sholom Wacholder and Nathaniel Rothman and Neil Caporaso
Cancer Epidemiology Biomarkers & Prevention, ISSN 1055-9965, 06/2002, Volume 11, Issue 6, pp. 513 - 520
TESTS | RISK | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | GENETIC ASSOCIATION | ONCOLOGY | FAMILY | Epidemiologic Studies | Genetic Predisposition to Disease | Reproducibility of Results | Demography | Neoplasms - etiology | Neoplasms - genetics | Bias | Humans | Research Design | Case-Control Studies | Neoplasms - epidemiology | Polymorphism, Genetic
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6. Full Text Association of germline variants in the APOBEC3 region with cancer risk and enrichment with APOBEC-signature mutations in tumors
by Middlebrooks, Candace D and Banday, A Rouf and Matsuda, Konichi and Udquim, Krizia-Ivana and Onabajo, Olusegun O and Paquin, Ashley and Figueroa, Jonine D and Zhu, Bin and Koutros, Stella and Kubo, Michiaki and Shuin, Taro and Freedman, Neal D and Kogevinas, Manolis and Malats, Nuria and Chanock, Stephen J and Garcia-Closas, Montserrat and Silverman, Debra T and Rothman, Nathaniel and Prokunina-Olsson, Ludmila
Nature Genetics, ISSN 1061-4036, 11/2016, Volume 48, Issue 11, pp. 1330 - 1338
High rates of APOBEC-signature mutations are found in many tumors, but factors affecting this mutation pattern are not well understood. Here we explored the... 
SURVIVAL | CYTIDINE DEAMINASES | INTERFERON | MUTAGENESIS | DNA | ENZYMES | GENETICS & HEREDITY | DELETION POLYMORPHISM | HYPERMUTATION | EXPRESSION | GENOME-WIDE ASSOCIATION | Genetic Predisposition to Disease | Risk Assessment | Cytidine Deaminase - genetics | Humans | Male | Chromosome Mapping | Proteins - genetics | Breast Neoplasms - genetics | Urinary Bladder Neoplasms - genetics | Mutagenesis | DNA, Neoplasm | Protein Isoforms | Minor Histocompatibility Antigens - genetics | Survival Analysis | Cell Line, Tumor | Germ-Line Mutation | Environment | Female | Polymorphism, Single Nucleotide | DNA, Single-Stranded | Mutation | Enzymes | Care and treatment | Genetic variation | Development and progression | Hydrolases | Genetic aspects | Gene expression | Health aspects | Bladder cancer | Genealogy | Genes | Breast cancer | Genomes | Medical screening | Studies | Consortia | Survival analysis | DNA methylation | Health risk assessment | Tumors
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7. Full Text Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
by Wacholder, Sholom and Chanock, Stephen and Garcia-Closas, Montserrat and El Ghormli, Laure and Rothman, Nathaniel
Journal of the National Cancer Institute, ISSN 0027-8874, 03/2004, Volume 96, Issue 6, pp. 434 - 442
Too many reports of associations between genetic variants and common cancer sites and other complex diseases are false positives. A major reason for this... 
BLADDER-CANCER | CANCER RISK | POLYMORPHISMS | METAANALYSIS | GENETIC ASSOCIATION | VARIANTS | ONCOLOGY | POPULATION STRATIFICATION | DISEASE | DISCOVERY RATE | REPAIR GENES | Haplotypes | Risk Assessment - methods | Confidence Intervals | Genetic Predisposition to Disease | Humans | False Positive Reactions | Molecular Epidemiology - methods | Genetic Variation | Likelihood Functions | Sample Size | Confounding Factors (Epidemiology) | Analysis of Variance | Bayes Theorem | Odds Ratio | Mathematical Computing | Observer Variation
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8. Full Text Bladder Cancer and Exposure to Water Disinfection By-Products through Ingestion, Bathing, Showering, and Swimming in Pools
by Villanueva, Cristina M and Cantor, Kenneth P and Grimalt, Joan O and Malats, Nuria and Silverman, Debra and Tardon, Adonina and Garcia-Closas, Reina and Serra, Consol and Carrato, Alfredo and Castaño-Vinyals, Gemma and Marcos, Ricard and Rothman, Nathaniel and Real, Francisco X and Dosemeci, Mustafa and Kogevinas, Manolis
American Journal of Epidemiology, ISSN 0002-9262, 1/2007, Volume 165, Issue 2, pp. 148 - 156
Bladder cancer has been associated with exposure to chlorination by-products in drinking water, and experimental evidence suggests that exposure also occurs... 
Trihalomethanes | Bladder neoplasms | Water supply | Skin absorption | Disinfection | Drinking | Inhalation | MICRONUCLEI | bladder neoplasms | FINLAND | drinking | disinfection | skin absorption | RISK | water supply | INDUCTION | CHLOROFORM | CHLORINATED DRINKING-WATER | inhalation | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | EPITHELIAL-CELLS | trihalomethanes | COHORT | Prognosis | Follow-Up Studies | Humans | Middle Aged | Risk Factors | Urinary Bladder Neoplasms - etiology | Male | Swimming Pools | Water Purification | Baths - adverse effects | Incidence | Environmental Exposure - adverse effects | Spain - epidemiology | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Urinary Bladder Neoplasms - epidemiology | Chlorination | Research | Bladder cancer | Risk factors | Prevalence studies (Epidemiology) | Water | Health risk assessment | Disinfection & disinfectants | Urogenital system | Human exposure | Cancer
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9. Full Text Detectable clonal mosaicism and its relationship to aging and cancer
by Jacobs, Kevin B and Yeager, Meredith and Zhou, Weiyin and Wacholder, Sholom and Wang, Zhaoming and Rodriguez-Santiago, Benjamin and Hutchinson, Amy and Deng, Xiang and Liu, Chenwei and Horner, Marie-Josephe and Cullen, Michael and Epstein, Caroline G and Burdett, Laurie and Dean, Michael C and Chatterjee, Nilanjan and Sampson, Joshua and Chung, Charles C and Kovaks, Joseph and Gapstur, Susan M and Stevens, Victoria L and Teras, Lauren T and Gaudet, Mia M and Albanes, Demetrius and Weinstein, Stephanie J and Virtamo, Jarmo and Taylor, Philip R and Freedman, Neal D and Abnet, Christian C and Goldstein, Alisa M and Hu, Nan and Yu, Kai and Yuan, Jian-Min and Liao, Linda and Ding, Ti and Qiao, You-Lin and Gao, Yu-Tang and Koh, Woon-Puay and Xiang, Yong-Bing and Tang, Ze-Zhong and Fan, Jin-Hu and Aldrich, Melinda C and Amos, Christopher and Blot, William J and Bock, Cathryn H and Gillanders, Elizabeth M and Harris, Curtis C and Haiman, Christopher A and Henderson, Brian E and Kolonel, Laurence N and Le Marchand, Loic and McNeill, Lorna H and Rybicki, Benjamin A and Schwartz, Ann G and Signorello, Lisa B and Spitz, Margaret R and Wiencke, John K and Wrensch, Margaret and Wu, Xifeng and Zanetti, Krista A and Ziegler, Regina G and Figueroa, Jonine D and Garcia-Closas, Montserrat and Malats, Nuria and Marenne, Gaelle and Prokunina-Olsson, Ludmila and Baris, Dalsu and Schwenn, Molly and Johnson, Alison and Landi, Maria Teresa and Goldin, Lynn and Consonni, Dario and Bertazzi, Pier Alberto and Rotunno, Melissa and Rajaraman, Preetha and Andersson, Ulrika and Freeman, Laura E. Beane and Berg, Christine D and Buring, Julie E and Butler, Mary A and Carreon, Tania and Feychting, Maria and Ahlbom, Anders and Gaziano, J Michael and Giles, Graham G and Hallmans, Goran and Hankinson, Susan E and Hartge, Patricia and Henriksson, Roger and Inskip, Peter D and Johansen, Christoffer and Landgren, Annelie and McKean-Cowdin, Roberta and Michaud, Dominique S and Melin, Beatrice S and Peters, Ulrike and Ruder, Avima M and Sesso, Howard D and Severi, Gianluca and Shu, Xiao-Ou and Visvanathan, Kala and ... and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Institutionen för strålningsvetenskaper and Näringsforskning and Onkologi and Umeå universitet
Nature Genetics, ISSN 1061-4036, 06/2012, Volume 44, Issue 6, pp. 651 - 658
In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, we observed large chromosomal abnormalities in a... 
MAFFUCCI SYNDROME | OLLIER DISEASE | ANEUPLOIDY | SUSCEPTIBILITY | GENETICS & HEREDITY | CHRONIC LYMPHOCYTIC-LEUKEMIA | MECHANISMS | MUTATIONS | GENOMIC IMBALANCES | ABERRATIONS | ASSOCIATION | Aging - genetics | Neoplasms - genetics | Humans | Middle Aged | Chromosome Aberrations | Female | Male | Mosaicism | Risk | Aged | Aging | Physiological aspects | Genetic aspects | Research | Cancer | Genotype & phenotype | Occupational safety | Bladder | Genomes | Mutation | Genetic testing | Chromosomes | Blood | Methods | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
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10. Full Text Improved Identification of von Hippel-Lindau Gene Alterations in Clear Cell Renal Tumors
by Michael L. Nickerson and Erich Jaeger and Yangu Shi and Jeffrey A. Durocher and Sunil Mahurkar and David Zaridze and Vsevolod Matveev and Vladimir Janout and Hellena Kollarova and Vladimir Bencko and Marie Navratilova and Neonilia Szeszenia-Dabrowska and Dana Mates and Anush Mukeria and Ivana Holcatova and Laura S. Schmidt and Jorge R. Toro and Sara Karami and Rayjean Hung and Gary F. Gerard and W. Marston Linehan and Maria Merino and Berton Zbar and Paolo Boffetta and Paul Brennan and Nathaniel Rothman and Wong-Ho Chow and Frederic M. Waldman and Lee E. Moore
Clinical Cancer Research, ISSN 1078-0432, 08/2008, Volume 14, Issue 15, pp. 4726 - 4734
Purpose: To provide a comprehensive, thorough analysis of somatic mutation and promoter hypermethylation of the von Hippel-Lindau ( VHL ) gene in the cancer... 
Tumor Markers | RCC | VHL | VHL GENE | SUPPRESSOR GENE | ONCOLOGY | CLONING | GERMLINE MUTATIONS | KIDNEY | CARCINOMA | CANCER | NUCLEASE | Neoplasms - metabolism | Promoter Regions, Genetic | Adenocarcinoma, Clear Cell - metabolism | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Male | Gene Expression Profiling | Kidney Neoplasms - metabolism | Case-Control Studies | Carcinoma, Renal Cell - metabolism | DNA Methylation | CpG Islands | Female | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Mutation | Adenocarcinoma, Clear Cell - genetics | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Index Medicus
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11. Full Text The Shanghai women's health study: Rationale, study design, and baseline characteristics
by Zheng, Wei and Chow, Wong-Ho and Yang, Gong and Jin, Fan and Rothman, Nathaniel and Blair, Aaron and Li, Hong-Lan and Wen, Wanqing and Ji, Bu-Tian and Li, Qi and Shu, Xiao-Ou and Gao, Yu-Tang
American Journal of Epidemiology, ISSN 0002-9262, 12/2005, Volume 162, Issue 11, pp. 1123 - 1131
Although cancer is a major cause of morbidity and mortality in most nations, the spectrum of cancer occurrence varies substantially worldwide. Most previous... 
Diet | Nutrition | Occupations | Neoplasms | Cohort studies | PANCREATIC-CANCER | BODY-FAT DISTRIBUTION | occupations | GREEN TEA CONSUMPTION | CHINESE-WOMEN | ENDOMETRIAL CANCER | nutrition | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | BREAST-CANCER RISK | cohort studies | SOY FOOD-CONSUMPTION | REPRODUCTIVE FACTORS | PHYSICAL-ACTIVITY | diet | neoplasms | CORONARY-HEART-DISEASE | Epidemiologic Research Design | Life Style | Age Distribution | Women's Health | Follow-Up Studies | Comorbidity | Diet - statistics & numerical data | Humans | Middle Aged | Specimen Handling - methods | China - epidemiology | Data Collection - methods | Socioeconomic Factors | Patient Selection | Neoplasms - urine | Neoplasms - blood | Obesity - epidemiology | Reproductive History | Adult | Female | Aged | Neoplasms - epidemiology | Cohort Studies | Women | Research | Epidemiologic methods | Epidemiology | Health aspects | Tumors
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12. Full Text Genome-wide association study identifies two susceptibility loci for osteosarcoma
by Savage, Sharon A and Mirabello, Lisa and Wang, Zhaoming and Gastier-Foster, Julie M and Gorlick, Richard and Khanna, Chand and Flanagan, Adrienne M and Tirabosco, Roberto and Andrulis, Irene L and Wunder, Jay S and Gokgoz, Nalan and Patiño-Garcia, Ana and Sierrasesúmaga, Luis and Lecanda, Fernando and Kurucu, Nilgün and Ilhan, Inci Ergurhan and Sari, Neriman and Serra, Massimo and Hattinger, Claudia and Picci, Piero and Spector, Logan G and Barkauskas, Donald A and Marina, Neyssa and De Toledo, Silvia Regina Caminada and Petrilli, Antonio S and Amary, Maria Fernanda and Halai, Dina and Thomas, David M and Douglass, Chester and Meltzer, Paul S and Jacobs, Kevin and Chung, Charles C and Berndt, Sonja I and Purdue, Mark P and Caporaso, Neil E and Tucker, Margaret and Rothman, Nathaniel and Landi, Maria Teresa and Silverman, Debra T and Kraft, Peter and Hunter, David J and Malats, Nuria and Kogevinas, Manolis and Wacholder, Sholom and Troisi, Rebecca and Helman, Lee and Fraumeni Jr, Joseph F and Yeager, Meredith and Hoover, Robert N and Chanock, Stephen J
Nature Genetics, ISSN 1061-4036, 07/2013, Volume 45, Issue 7, pp. 799 - 803
Osteosarcoma is the most common primary bone malignancy of adolescents and young adults. To better understand the genetic etiology of osteosarcoma, we... 
GENETIC-VARIATION | RATES | LINKAGE DISEQUILIBRIUM | BONE CANCER | POLYMORPHISMS | GENETICS & HEREDITY | TUMOR | RECEPTOR | COMMON | RECOMBINATION HOTSPOTS | CHILDREN | Osteosarcoma | Development and progression | Disease susceptibility | Genetic aspects | Research | Single nucleotide polymorphisms | Health aspects | Medical research | Pediatrics | Genealogy | Biomedical research | Oncology | Genomes | Grants | DNA repair | Children & youth | Studies | Confidence intervals | Disease prevention | Bone cancer | Quality control | Genetics | Deoxyribonucleic acid--DNA
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13. Full Text Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
by Wolpin, Brian M and Rizzato, Cosmeri and Kraft, Peter and Kooperberg, Charles and Petersen, Gloria M and Wang, Zhaoming and Arslan, Alan A and Beane-Freeman, Laura and Bracci, Paige M and Buring, Julie and Canzian, Federico and Duell, Eric J and Gallinger, Steven and Giles, Graham G and Goodman, Gary E and Goodman, Phyllis J and Jacobs, Eric J and Kamineni, Aruna and Klein, Alison P and Kolonel, Laurence N and Kulke, Matthew H and Li, Donghui and Malats, Núria and Olson, Sara H and Risch, Harvey A and Sesso, Howard D and Visvanathan, Kala and White, Emily and Zheng, Wei and Abnet, Christian C and