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SCIENTIFIC REPORTS, ISSN 2045-2322, 09/2019, Volume 9, Issue 1, pp. 1 - 13
The endothelial glycocalyx and its regulated shedding are important to vascular health. Endo-beta-D-glucuronidase heparanase-1 (HPSE1) is the only enzyme that... 
CELLS | ACTIVATION | GENE DELIVERY | SULFATE | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TOLL-LIKE RECEPTORS | SYSTEMS | CD14 | EXPRESSION | Heparan sulfate | Intravenous administration | Kidneys | TLR4 protein | Tumor necrosis factor-α | CD14 antigen | Endothelial cells | Lipopolysaccharides | Interleukin 6 | Cell activation | Toll-like receptors | Sepsis | Microvasculature | Capillaries
Journal Article
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 06/2011, Volume 300, Issue 6, pp. 851 - 862
A synthetic 7-mer, HHHRHSF, was recently identified by screening a phage display library for binding to the Tie-2 receptor. A polyethylene-oxide clustered... 
Acute lung injury | Vasculotide | Tie-2/TEK | Angiopoietins | Sepsis | Endothelial permeability | Vascular leakage | Endotoxin | MIGRATION | PHYSIOLOGY | ANGIOGENESIS | angiopoietins | AIRWAY INFLAMMATION | RECEPTOR | endothelial permeability | acute lung injury | RESPIRATORY-DISTRESS-SYNDROME | vascular leakage | LEAKAGE | vasculotide | RESPIRATORY SYSTEM | TIE2-EXPRESSING MONOCYTES | EXCESS CIRCULATING ANGIOPOIETIN-2 | sepsis | endotoxin | BLOOD | Endothelium, Vascular - cytology | Endotoxemia - prevention & control | Humans | Capillary Permeability - drug effects | Endotoxemia - chemically induced | Endothelium, Vascular - drug effects | Male | Peptide Fragments - pharmacology | Polyethylene Glycols - chemistry | Immunoenzyme Techniques | Lung Injury - mortality | Lung Injury - prevention & control | Polyethylene Glycols - metabolism | Receptor, TIE-2 - agonists | Mice, Inbred C57BL | RNA, Messenger - genetics | Survival Rate | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Polyethylene Glycols - administration & dosage | Peptide Fragments - chemical synthesis | Animals | Lipopolysaccharides - pharmacology | Mice | Endotoxemia - mortality | Lung Injury - chemically induced | Endotoxins - adverse effects | Physiological aspects | Care and treatment | Angiogenin | Health aspects | Lung diseases | Tie-2 | TEK
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, pp. e0139147 - e0139147
Epidemiologic studies show a correlation between the dietary intake of food polyphenols and beneficial health effects. Several in vitro studies indicate that... 
SOLUBLE EPOXIDE HYDROLASE | RESVERATROL ANALOGS | OXIDATIVE STRESS | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | CYCLOOXYGENASE-2 EXPRESSION | CHEMOPREVENTIVE AGENT | ARACHIDONIC-ACID | NF-KAPPA-B | PROSTAGLANDIN E-2 | MASS-SPECTROMETRY | Anti-Inflammatory Agents - pharmacology | Humans | Mice, Inbred C57BL | Cells, Cultured | Polyphenols - pharmacology | Male | Monocytes - metabolism | Celecoxib - pharmacology | Stilbenes - pharmacology | Enzyme Activation - drug effects | Indomethacin - pharmacology | Monocytes - drug effects | Animals | Cyclooxygenase 2 - metabolism | Genistein - pharmacology | Lipopolysaccharides - pharmacology | Cell Line, Tumor | Real-Time Polymerase Chain Reaction | Apigenin - pharmacology | Physiological aspects | Polyphenols | Cyclooxygenases | Genetic aspects | Research | Gene expression | Nephrology | Genistein | Cytotoxicity | Arachidonic acid | Veterinary medicine | Epidemiology | Lipopolysaccharides | Toxicology | Metabolites | Resveratrol | Pretreatment | Food | Analytical chemistry | Medical research | Dexamethasone | Inflammation | Dietary intake | Bioavailability | Celecoxib | Mode of action | Inflammatory bowel disease | Studies | Monocytes | Diet | Food intake | Correlation analysis | Sepsis | In vivo methods and tests | Indomethacin | Cyclooxygenase-2 | Cancer | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e37100
Extracellular adenosine formed by 5'-ectonucleotidase (CD73) is involved in tubulo-glomerular feedback in the kidney but is also known to be an important... 
ECTO-5'-NUCLEOTIDASE | ADENOSINE RECEPTORS | CD73 | PATHWAY | INFLAMMATION | IL-18 | MULTIDISCIPLINARY SCIENCES | RECEPTOR ACTIVATION | THERAPEUTIC TARGETS | GENERATION | PROTECTS | Autoimmunity | Cell Count | Tumor Necrosis Factor-alpha - blood | Male | 5'-Nucleotidase - deficiency | Acute Kidney Injury - immunology | Capillaries - metabolism | Podocytes - metabolism | Interleukin-18 - blood | Acute Kidney Injury - pathology | Complement C3 - metabolism | Endothelial Cells - metabolism | Mesangial Cells - immunology | Vascular Endothelial Growth Factor A - blood | Proteinuria - metabolism | Mesangial Cells - metabolism | Podocytes - pathology | Acute Kidney Injury - physiopathology | Chemokine CXCL2 - blood | Endothelial Cells - immunology | Phenotype | Animals | Up-Regulation - immunology | Podocytes - immunology | Mesangial Cells - pathology | Adenosine - metabolism | Mice | 5'-Nucleotidase - metabolism | Acute Kidney Injury - metabolism | Endothelial Cells - pathology | Immunoglobulin G - metabolism | Inflammation | Mediation | Vascular endothelial growth factor | Nucleotidases | Nucleotidase | Nephrology | Renal function | Laboratories | Syngeneic grafts | CD8 antigen | Immunoglobulin G | Immune clearance | Medical schools | Proteins | Lymphocytes | Rodents | Atherosclerosis | CD25 antigen | CD73 antigen | Capillaries | Age | Creatinine | Urine | Adenosine | CD11b antigen | Kidneys | Cytokines | Neutrophils | Tumor necrosis factor-α | Metabolism | Endothelium | Interleukin 18 | Medicine | Serum levels | Tumor necrosis factor | Fibrosis | Ligands | Ectonucleotidase | Chemokines | Proteinuria | Kidney transplantation
Journal Article
Journal Article
Journal Article
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, ISSN 0931-0509, 06/2019, Volume 34, Issue 6, pp. 947 - 960
Background Peritoneal membrane (PM) damage during peritoneal dialysis (PD) is mediated largely by high glucose (HG)-induced pro-inflammatory and neo-angiogenic... 
macrophage polarization | fibrosis | peritoneal dialysis | inflammation | protein kinase C | IMMUNE-RESPONSE | ISOFORMS | ELEVATED GLUCOSE | PKC | DIALYSIS | TRANSPLANTATION | EPITHELIAL-MESENCHYMAL TRANSITION | INHIBITION | UROLOGY & NEPHROLOGY | TNF-ALPHA | ALTERNATIVE ACTIVATION
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 12/2002, Volume 110, Issue 12, pp. 1823 - 1830
IgG Fc receptors (FcgammaRs, especially FcgammaRIII) and complement (in particular, C5a anaphylatoxin) are critical effectors of the acute inflammatory... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHEMOKINE GENERATION | TUMOR-NECROSIS-FACTOR | IN-VIVO | MAST-CELLS | ALVEOLAR MACROPHAGES | RECEPTOR | DEFICIENT MICE | GOODPASTURES-SYNDROME | REVERSE ARTHUS REACTION | NEUTROPHIL RECRUITMENT
Journal Article
Kidney International, ISSN 0085-2538, 06/2016, Volume 89, Issue 6, pp. 1253 - 1267
Journal Article
Nephrology Dialysis Transplantation, ISSN 0931-0509, 05/2018, Volume 33, Issue suppl_1, pp. i195 - i195
Journal Article