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1. Full Text The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group
by Leung, Nelson and Bridoux, Frank and Batuman, Vecihi and Chaidos, Aristeidis and Cockwell, Paul and D’Agati, Vivette D and Dispenzieri, Angela and Fervenza, Fernando C and Fermand, Jean-Paul and Gibbs, Simon and Gillmore, Julian D and Herrera, Guillermo A and Jaccard, Arnaud and Jevremovic, Dragan and Kastritis, Efstathios and Kukreti, Vishal and Kyle, Robert A and Lachmann, Helen J and Larsen, Christopher P and Ludwig, Heinz and Markowitz, Glen S and Merlini, Giampaolo and Mollee, Peter and Picken, Maria M and Rajkumar, Vincent S and Royal, Virginie and Sanders, Paul W and Sethi, Sanjeev and Venner, Christopher P and Voorhees, Peter M and Wechalekar, Ashutosh D and Weiss, Brendan M and Nasr, Samih H
Nature reviews. Nephrology, ISSN 1759-5061, 01/2019, Volume 15, Issue 1, pp. 45 - 59
Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Genetic Testing | Paraproteinemias - pathology | Biopsy | Kidney Diseases - pathology | Paraproteinemias - diagnosis | Humans | Kidney Diseases - diagnosis | Paraproteinemias - genetics | Kidney Diseases - blood | Paraproteinemias - blood | Biomarkers - blood | Kidney Diseases - genetics | Monoclonal gammopathies | Diagnosis | Kidney diseases | Immunoglobulins | Index Medicus | Pathology | Oncogenesis | Nephritis | Renal cancer | Consensus Statement | Kidney
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2. Full Text Are toll-like receptors potential drug targets for atherosclerosis? Evidence from genetic studies to date
by Nelson, Christopher P and Nelson, Christopher P and Erridge, Clett and Erridge, Clett
Immunogenetics (New York), ISSN 0093-7711, 1/2019, Volume 71, Issue 1, pp. 1 - 11
Human Genetics | Gene Function | Allergology | Biomedicine | Immunology | Drug target discovery | Toll-like receptors | Cardiovascular disease | Genetics | Mendelian randomisation | Cell Biology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Genome-Wide Association Study | Atherosclerosis - drug therapy | Atherosclerosis - genetics | Humans | Immunity, Innate | Atherosclerosis - etiology | Animals | Toll-Like Receptors - genetics | Mendelian Randomization Analysis | Toll-Like Receptors - antagonists & inhibitors | Toll-Like Receptors - physiology | Signal Transduction - physiology | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Animal models | Target recognition | Glucocorticoids | Intracellular signalling | Lipids | Drug development | Epidemiology | Immunosuppressive agents | Proteins | Signal transduction | Receptors | Atherosclerosis | Nonsteroidal anti-inflammatory drugs | Heart diseases | Statins | Immune system | Immune response | Antiinflammatory agents | Coronary artery | Health risks | Inflammation | Coronary artery disease | Low density lipoprotein | Cholesterol | Side effects | Arteriosclerosis | Cardiovascular diseases | Index Medicus
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3. Full Text DNA methylation and body-mass index: a genome-wide analysis
by Dick, Katherine J, PhD and Nelson, Christopher P, PhD and Tsaprouni, Loukia, PhD and Sandling, Johanna K, PhD and Aïssi, Dylan, MSc and Wahl, Simone, MSc and Meduri, Eshwar, PhD and Morange, Pierre-Emmanuel, Prof and Gagnon, France, PhD and Grallert, Harald, PhD and Waldenberger, Melanie, PhD and Peters, Annette, Prof and Erdmann, Jeanette, Prof and Hengstenberg, Christian, Prof and Cambien, Francois, Prof and Goodall, Alison H, Prof and Ouwehand, Willem H, Prof and Schunkert, Heribert, Prof and Thompson, John R, Prof and Spector, Tim D, FRCP and Gieger, Christian, PhD and Trégouët, David-Alexandre, PhD and Deloukas, Panos, Prof and Samani, Nilesh J, Prof
The Lancet (British edition), ISSN 0140-6736, 2014, Volume 383, Issue 9933, pp. 1990 - 1998
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Body Mass Index | Chromosomes, Human, Pair 19 - genetics | Genome-Wide Association Study | Basic Helix-Loop-Helix Transcription Factors - genetics | Humans | Middle Aged | Polymorphism, Single Nucleotide - genetics | Female | Male | DNA Methylation - genetics | Chromosomes, Human, Pair 15 - genetics | Obesity - genetics | Obesity | Epigenetic inheritance | Genetic variation | Genetic research | Genetic aspects | Research | Identification and classification | Medical research | Body mass index | DNA methylation | Epigenetics | Genomes | Gene expression | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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4. Genomic Risk Prediction of Coronary Artery Disease in 480,000 Adults: Implications for Primary Prevention
by Inouye, Michael and Abraham, Gad and Nelson, Christopher P and Wood, Angela M and Sweeting, Michael J and Dudbridge, Frank and Lai, Florence Y and Kaptoge, Stephen and Brozynska, Marta and Wang, Tingting and Ye, Shu and Webb, Thomas R and Rutter, Martin K and Tzoulaki, Ioanna and Patel, Riyaz S and Loos, Ruth J.F and Keavney, Bernard and Hemingway, Harry and Thompson, John and Watkins, Hugh and Deloukas, Panos and Di Angelantonio, Emanuele and Butterworth, Adam S and Danesh, John and Samani, Nilesh J and UK Biobank CardioMetabolic Cons and UK Biobank CardioMetabolic Consortium CHD Working Group
Journal of the American College of Cardiology, ISSN 0735-1097, 10/2018, Volume 72, Issue 16, pp. 1883 - 1893
coronary artery disease | primary prevention | genomic risk prediction | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Genomics - statistics & numerical data | Predictive Value of Tests | Risk Assessment - methods | Genome-Wide Association Study | Humans | Middle Aged | Risk Factors | Male | Mass Screening - methods | Multifactorial Inheritance | Coronary Artery Disease - diagnosis | Coronary Artery Disease - genetics | Primary Prevention - methods | Female | Coronary Artery Disease - epidemiology | Genomics - methods | Research Design | United Kingdom - epidemiology | Heart attacks | Angioplasty | Lipids | Cardiovascular disease | Genomes | Family medical history | Risk factors | Confidence intervals | Body mass index | Health and safety screening | Population | Genetics | Blood pressure | Heart diseases | Age | Hypertension | Diabetes mellitus | Coronary artery | Health risks | Assessment centers | Trajectories | Risk analysis | Coronary artery disease | Cholesterol | Studies | Disease prevention | Genetic variance | Hospitals | Body mass | Body size | Coronary vessels | Adults | Heritability | Diabetes | Health risk assessment | Smoking
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5. Full Text Adult height and risk of 50 diseases: A combined epidemiological and genetic analysis
by Lai, Florence Y and Nath, Mintu and Hamby, Stephen E and Thompson, John R and Nelson, Christopher P and Samani, Nilesh J
BMC medicine, ISSN 1741-7015, 10/2018, Volume 16, Issue 1, pp. 187 - 187
Genetically determined height | Disease risk | Instrumental variables | Adult height | Mendelian randomisation | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Disease - etiology | Mendelian Randomization Analysis - methods | Disease - genetics | Humans | Middle Aged | Risk Factors | Adult | Female | Male | Aged | Genetic Testing - methods | Body Height - genetics | Stature | Analysis | Genetic research | Adults | Health aspects | Epidemiology | Risk factors | Diseases | Cardiac arrhythmia | Risk | Cardiovascular disease | Systematic review | Intervertebral discs | Hernia | Consortia | Vasculitis | Fibrillation | Genetic analysis | Thromboembolism | Heart diseases | Hypertension | Coronary artery | Health risks | Breast cancer | Regression analysis | Coronary artery disease | Biological activity | Hip | Esophagus | Studies | Genetic variance | Body height | Fractures | Coronary vessels | Health risk assessment | Cancer | Index Medicus
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6. Full Text Truancy in the United States: Examining temporal trends and correlates by race, age, and gender
by Maynard, Brandy R and Vaughn, Michael G and Nelson, Erik J and Salas-Wright, Christopher P and Heyne, David A and Kremer, Kristen P
Children and youth services review, ISSN 0190-7409, 10/2017, Volume 81, pp. 188 - 196
Substance use | Truancy | School attendance problems | School engagement | Delinquency | Social Work | Social Sciences | Family Studies | Drugs and youth | Analysis | Intervention | Parental control | Hispanic Americans | Economic factors | Risk | Gender | Risk factors | Childrearing practices | Alcohol use | Parents & parenting | Risk assessment | Race | Ethnic groups | Teenagers | Trends | Adolescents | Psychosocial factors | Youth | Substance abuse | Minority & ethnic groups | Ethnicity | Socioeconomic factors | Marijuana | Sociodemographics | substance use | delinquency | school attendance problems | school engagement | truancy
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7. Full Text HLA-B5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin
by Daly, Ann K and Donaldson, Peter T and Bhatnagar, Pallav and Shen, Yufeng and Pe'Er, Itsik and Floratos, Aris and Daly, Mark J and Goldstein, David B and John, Sally and Nelson, Matthew R and Graham, Julia and Park, B Kevin and Dillon, John F and Bernal, William and Cordell, Heather J and Pirmohamed, Munir and Aithal, Guruprasad P and Day, Christopher P and DILIGEN Study and International SAE Consortium and for the DILIGEN study
Nature genetics, ISSN 1061-4036, 07/2009, Volume 41, Issue 7, pp. 816 - 819
Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Genome-Wide Association Study | Humans | Female | Male | Chemical and Drug Induced Liver Injury - genetics | Floxacillin - adverse effects | HLA-B Antigens - genetics | Case-Control Studies | Complications and side effects | Flucloxacillin | Histocompatibility antigens | Liver diseases | Genetic susceptibility | HLA histocompatibility antigens | Genetic aspects | Research | Health aspects | Risk factors | Drugs | Confidence intervals | Regulatory agencies | Genotype & phenotype | Genes | Clinical trials | Genetics | Principal components analysis | Index Medicus
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8. Full Text Handgun Carrying among White Youth Increasing in the United States: New Evidence from the National Survey on Drug Use and Health 2002–2013
by Vaughn, Michael G and Nelson, Erik J and Salas-Wright, Christopher P and DeLisi, Matt and Qian, Zhengmin
Preventive medicine, ISSN 0091-7435, 2015, Volume 88, pp. 127 - 133
Internal Medicine | Firearms | Adolescents | Youth violence | Handgun carrying | Weapon-carrying | Medicine, General & Internal | Public, Environmental & Occupational Health | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Ethnic Groups - statistics & numerical data | Prevalence | United States | Drug Trafficking - trends | Humans | Self Report | Male | Urban Population | Firearms - statistics & numerical data | Socioeconomic Factors | Adolescent Behavi