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Analytical Chemistry, ISSN 0003-2700, 1999, Volume 71, Issue 1, pp. 235 - 242
Journal Article
Journal Article
Journal Article
Nature Biotechnology, ISSN 1087-0156, 09/2007, Volume 25, Issue 9, pp. 1035 - 1044
Journal Article
Nature, ISSN 0028-0836, 03/2006, Volume 440, Issue 7084, pp. 631 - 636
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 02/2004, Volume 6, Issue 2, pp. 97 - 105
Journal Article
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 06/2012, Volume 8, Issue 6, pp. 576 - 582
We devised a high-throughput chemoproteomics method that enabled multiplexed screening of 16,000 compounds against native protein and lipid kinases in cell... 
RHEUMATOID-ARTHRITIS | PI3K | CLASS-IB | INSULIN-RESISTANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCED INFLAMMATION | KEY ROLE | KINASE INHIBITORS | JOINT INFLAMMATION | CHEMOPROTEOMICS | IDENTIFICATION | Small Molecule Libraries - pharmacology | Arthritis, Experimental - drug therapy | Rats, Wistar | Humans | Interleukin-17 - immunology | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Structure-Activity Relationship | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Arthritis, Experimental - pathology | T-Lymphocytes, Helper-Inducer - drug effects | Enzyme Inhibitors - pharmacokinetics | T-Lymphocytes, Helper-Inducer - immunology | Enzyme Inhibitors - chemistry | T-Lymphocytes, Helper-Inducer - enzymology | T-Lymphocytes, Helper-Inducer - cytology | Mice, Inbred DBA | Molecular Structure | Binding, Competitive | Cell Line | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Small Molecule Libraries - therapeutic use | Rats | Arthritis, Experimental - immunology | Drug Discovery | Enzyme Inhibitors - therapeutic use | Cell Movement - drug effects | Small Molecule Libraries - chemistry | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Cell Differentiation - drug effects | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Mice | Class Ib Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Small Molecule Libraries - pharmacokinetics | Index Medicus
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2011, Volume 42, Issue 1, pp. 84 - 95
Adrenergic stimulation of the heart engages cAMP and phosphoinositide second messenger signaling cascades. Cardiac phosphoinositide 3-kinase p110γ participates... 
PATHWAYS | RECRUITMENT | REGULATORY SUBUNIT RII | PRESSURE-OVERLOAD | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEART-FAILURE | DEPENDENT PROTEIN-KINASE | CARDIOMYOCYTES | PI3K-GAMMA | RECEPTORS | PHOSPHOINOSITIDE 3-KINASE | CELL BIOLOGY | Phosphorylation | Phosphatidylinositol Phosphates - metabolism | Class Ib Phosphatidylinositol 3-Kinase - genetics | Humans | Molecular Sequence Data | Cyclic AMP-Dependent Protein Kinase RIIalpha Subunit - metabolism | Quinoxalines - pharmacology | Class Ib Phosphatidylinositol 3-Kinase - chemistry | Base Sequence | Class Ib Phosphatidylinositol 3-Kinase - metabolism | Class Ib Phosphatidylinositol 3-Kinase - deficiency | Cyclic Nucleotide Phosphodiesterases, Type 3 - metabolism | Receptors, Adrenergic, beta - metabolism | Thiazolidinediones - pharmacology | Cyclic AMP - metabolism | Peptide Fragments - genetics | A Kinase Anchor Proteins - metabolism | Second Messenger Systems | Cyclic AMP-Dependent Protein Kinases - metabolism | Amino Acid Sequence | Cell Line | Peptide Fragments - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Heart Failure - metabolism | Heart Failure - drug therapy | Mice, Knockout | Protein Interaction Mapping | DNA - genetics | Sequence Homology, Amino Acid | Peptide Fragments - chemistry | Animals | Myocytes, Cardiac - metabolism | Mice | Class Ib Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Enzyme Activation | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 01/2002, Volume 415, Issue 6868, pp. 141 - 147
Journal Article