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Pediatric Blood & Cancer, ISSN 1545-5009, 01/2018, Volume 65, Issue 1, pp. e26834 - n/a
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2015, Volume 16, Issue 9, pp. 1111 - 1122
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16666 - 16671
Hutchinson–Gilford progeria syndrome (HGPS) is an extremely rare, fatal, segmental premature aging syndrome caused by a mutation in LMNA that produces the... 
Pediatrics | Progeria | Sensorineural hearing loss | Bones | Children | Lamins | Weight gain | Child health services | Vascular stiffness | Audiology | Cardiovascular disease | SCH66336 | Laminopathy | Translational medicine | cardiovascular disease | translational medicine | PULSE-WAVE VELOCITY | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | REFERENCE VALUES | LAMIN | FARNESYL TRANSFERASE INHIBITORS | HEALTHY-CHILDREN | MOUSE MODEL | DISEASE | BONE | PROGRESSION | laminopathy | Carotid Arteries - drug effects | Pulse Wave Analysis | Humans | Child, Preschool | Pyridines - pharmacokinetics | Male | Fatigue - chemically induced | Diarrhea - chemically induced | Progeria - drug therapy | Dose-Response Relationship, Drug | Farnesyltranstransferase - metabolism | Pyridines - adverse effects | Enzyme Inhibitors - pharmacokinetics | Progeria - physiopathology | Progeria - pathology | Female | Piperidines - pharmacokinetics | Weight Gain - drug effects | Farnesyltranstransferase - antagonists & inhibitors | Child | Pyridines - therapeutic use | Enzyme Inhibitors - adverse effects | Drug Administration Schedule | Treatment Outcome | Enzyme Inhibitors - therapeutic use | Vomiting - chemically induced | Piperidines - therapeutic use | Piperidines - adverse effects | Adolescent | Carotid Arteries - pathology | Transferases | Clinical trials | Physiological aspects | Development and progression | Health aspects | Methods | Proteins | Genotype & phenotype | Genetic disorders | Medical treatment | Atherosclerosis | Mutation | Children & youth | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2016, Volume 113, Issue 48, pp. E7701 - E7709
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2011, Volume 364, Issue 26, pp. 2496 - 2506
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2010, Volume 11, Issue 10, pp. 950 - 961
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, pp. 217 - 221
Effective anti-tumour immunity in humans has been associated with the presence of T cells directed at cancer neoantigens(1), a class of HLA-bound peptides that... 
IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | CD4(+) T-CELLS | ANTIGENS | CANCER-IMMUNOTHERAPY | SEQUENCING DATA | EXPRESSION | PEPTIDE | PREDICTION | MOLECULES | EPITOPES | Amino Acid Sequence | Antigens, Neoplasm - genetics | Antibodies, Monoclonal, Humanized - therapeutic use | Neoplasm Recurrence, Local - prevention & control | Antigens, Neoplasm - immunology | Humans | Cancer Vaccines - adverse effects | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Cancer Vaccines - chemistry | Antigens, Neoplasm - chemistry | Machine Learning | CD4-Positive T-Lymphocytes - immunology | Neoplasm Recurrence, Local - immunology | Cancer Vaccines - immunology | Histocompatibility Antigens Class II - immunology | Melanoma - genetics | Melanoma - immunology | Antibodies, Monoclonal, Humanized - pharmacology | Patient Safety | High-Throughput Nucleotide Sequencing | Mutation | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Precision Medicine - methods | Care and treatment | Methods | Melanoma | Cancer | Peptides | PD-1 protein | CD8 antigen | Vaccination | Feasibility analysis | Lymphocytes T | Vaccines | Tissues | Immunity | Thymus | Lymphocytes | Immunotherapy | Antigens | Feasibility studies | T cell receptors | Gene expression | Patients | Immunological tolerance | CD4 antigen | Studies | Immune checkpoint | Immunogenicity | Cell death | Histocompatibility antigen HLA | Tumors | Apoptosis | Index Medicus
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 10/2016, Volume 12, Issue 10, pp. 845 - 852
Hydrocarbon-stapled peptides are a class of bioactive alpha-helical ligands developed to dissect and target protein interactions. While there is consensus that... 
Animals | Hydrocarbons - chemistry | Peptides - metabolism | Peptides - chemistry | Peptides - pharmacokinetics | Hydrocarbons - metabolism | Fibroblasts - cytology | Mice | Hydrocarbons - pharmacokinetics | Fibroblasts - metabolism | Biophysics | Permeability | Peptides | Cells | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 2, pp. 111 - 121
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 12/2014, Volume 371, Issue 26, pp. 2488 - 2498
Journal Article