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science & technology (26) 26
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1. Full Text Peptide-MHC-based nanomedicines for autoimmunity function as T-cell receptor microclustering devices
by Singha, Santiswarup and Shao, Kun and Yang, Yang and Clemente-Casares, Xavier and Solé, Patricia and Clemente, Antonio and Blanco, Jesús and Dai, Qin and Song, Fayi and Liu, Shang Wan and Yamanouchi, Jun and Umeshappa, Channakeshava Sokke and Nanjundappa, Roopa Hebbandi and Detampel, Pascal and Amrein, Matthias and Fandos, César and Tanguay, Robert and Newbigging, Susan and Serra, Pau and Khadra, Anmar and Chan, Warren C. W and Santamaria, Pere
Nature nanotechnology, ISSN 1748-3387, 07/2017, Volume 12, Issue 7, pp. 701 - 710
Science & Technology - Other Topics | Materials Science | Nanoscience & Nanotechnology | Technology | Materials Science, Multidisciplinary | Science & Technology | Autoimmunity | Histocompatibility Antigens - immunology | Nanoparticles - chemistry | Peptides - chemistry | Humans | Peptides - immunology | Histocompatibility Antigens - chemistry | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Animals | Nanomedicine - methods | Mice, Inbred NOD | Mice | Formulations | Antigens | Hematology | Toxicity | Immunoregulation | Abnormalities | Zebrafish | Lymphocytes T | T cell receptors | Embryos | Biological activity | Nanoparticles | T-cell receptor | Engineering | Phagocytes | Receptors | Major histocompatibility complex | Lymphocytes | Ligands | Biocompatibility | Differentiation | Nanotechnology | Index Medicus
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2. Full Text In vivo Quantum‐Dot Toxicity Assessment
by Hauck, Tanya S and Anderson, Robin E and Fischer, Hans C and Newbigging, Susan and Chan, Warren C. W
Small (Weinheim an der Bergstrasse, Germany), ISSN 1613-6810, 01/2010, Volume 6, Issue 1, pp. 138 - 144
toxicity | quantum dots | biodistribution | nanostructures | Nanostructures | Quantum dots | Toxicity | Biodistribution | Materials Science | Materials Science, Multidisciplinary | Physics, Condensed Matter | Science & Technology - Other Topics | Chemistry, Physical | Physics | Science & Technology | Physics, Applied | Physical Sciences | Chemistry | Nanoscience & Nanotechnology | Technology | Chemistry, Multidisciplinary | Selenium - toxicity | Rats | Selenium Compounds - toxicity | Materials Testing | Metabolic Clearance Rate | Organ Specificity | Rats, Sprague-Dawley | Tissue Distribution | Sulfides | Animals | Quantum Dots | Selenium Compounds - pharmacokinetics | Cadmium Compounds - toxicity | Cadmium Compounds - pharmacokinetics | Selenium - pharmacokinetics | Index Medicus
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3. Full Text High-throughput discovery of novel developmental phenotypes
by Dickinson, Mary E and Ji, Xiao and Teboul, Lydia and Wong, Michael D and White, Jacqueline K and Meehan, Terrence F and Westerberg, Henrik and Adissu, Hibret and Baker, Candice N and Brianna Caddle, L and Chiani, Francesco and Clary, Dave and Cleak, James and Daly, Mark J and Denegre, James M and Edie, Sarah M and Gailus-Durner, Valerie and Galli, Antonella and Gambadoro, Alessia and Gallegos, Juan and Johnson, Sara J and Lawson, Thomas N and Lek, Monkol and Mason, Jeremy and McElwee, Melissa L and Nutter, Lauryl M.J and Rowland, Douglas J and Samocha, Kaitlin E and Seavitt, John R and Szoke-Kovacs, Zsombor and Trainor, Amanda G and Wakana, Shigeharu and Warren, Jonathan and West, David B and Tocchini-Valentini, Glauco P and Flicek, Paul and Bradley, Allan and Skarnes, William C and Justice, Monica J and Parkinson, Helen E and Moore, Mark and Wells, Sara and Svenson, Karen L and Herault, Yann and Mallon, Ann-Marie and Mark Henkelman, R and Brown, Steve D.M and Adams, David J and Kent Lloyd, K.C and McKerlie, Colin and Urban, Barbara and Lund, Caroline and LaCasse, Taylor and Mehalow, Adrienne and Taft, Robert and Kutney, Peter and Goodwin, Leslie and Kales, Susan and Urban, Rachel and Palmer, Kristina and Pertuy, Fabien and Bitz, Deborah and Weber, Bruno and Jacobs, Hughes and Ennah, Hamid and Ali-Hadji, Dalila and Wattenhofer-Donze, Marie and André, Philippe and Birling, Marie-Christine and Pavlovic, Guillaume and Sorg, Tania and Morse, Iva and Benso, Frank and Harrison, Jackie and Guo, Ruolin and Qu, Dawei and Spring, Shoshana and Ellegood, Jacob and Shang, Xueyuan and Feugas, Pat and Creighton, Amie and Penton, Patricia Castellanos and Danisment, Ozge and Griggs, Nicola and Tudor, Catherine L and Green, Angela L and Icoresi Mazzeo, Cecilia and Siragher, Emma and Lillistone, Charlotte and Gleeson, Diane and Sethi, Debarati and Bayzetinova, Tanya and Burvill, Jonathan and Habib, Bishoy and Maswood, Ryea and Woods, Michael and Grau, Evelyn and Sinclair, Caroline and Brown, Ellen and Ayabe, Shinya and Int Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature (London), ISSN 0028-0836, 09/2016, Volume 537, Issue 7621, pp. 508 - 514
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genetic research | Phenotype | Research | High-throughput screening (Biochemical assaying) | Methods | Genotype & phenotype | Disease | Developmental biology | Genes | Genomes | Mutation | Embryos | Index Medicus | knockout | embryonic lethal | mouse | KOMP | IMPC | EUCOMM
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4. Full Text High Resolution Imaging and Histopathological Characterization of Myocardial Infarction
by Lin, Peter and Westreich, Jared and Li, Mengyuan and Gribble, Adam and Newbigging, Susan and Vitkin, Alex and Pop, Mihaela
Biophysical journal, ISSN 0006-3495, 02/2019, Volume 116, Issue 3, pp. 231a - 231a
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5. Full Text Hemorrhage promotes inflammation and myocardial damage following acute myocardial infarction: Insights from a novel preclinical model and cardiovascular magnetic resonance
by Ghugre, Nilesh R and Pop, Mihaela and Thomas, Reuben and Newbigging, Susan and Qi, Xiuling and Barry, Jennifer and Strauss, Bradley H and Wright, Graham A
Journal of cardiovascular magnetic resonance, ISSN 1097-6647, 07/2017, Volume 19, Issue 1, pp. 50 - 50
Myocardial infarction | Microvascular obstruction | Inflammation | Ischemia reperfusion injury | cardiovascular magnetic resonance | Hemorrhage | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Coronary Circulation | Hemorrhage - diagnostic imaging | Predictive Value of Tests | Edema, Cardiac - diagnostic imaging | Hemorrhage - physiopathology | Myocardium - pathology | Edema, Cardiac - physiopathology | Myocardial Infarction - diagnostic imaging | Magnetic Resonance Imaging, Cine | Microcirculation | Animals | Time Factors | Contrast Media - administration & dosage | Myocardial Infarction - pathology | Myocarditis - diagnostic imaging | Edema, Cardiac - pathology | Female | Myocardial Infarction - physiopathology | Gadolinium DTPA - administration & dosage | Myocarditis - pathology | Hemorrhage - pathology | Myocarditis - physiopathology | Sus scrofa | Disease Models, Animal | Care and treatment | Usage | Magnetic resonance imaging | Diagnosis | Heart attack | Risk factors | Heart | Occlusion | Edema | Stroke | Damage assessment | Heart attacks | Nuclear magnetic resonance--NMR | Magnetic resonance | Staining | Gadolinium | Inflammatory response | Mapping | Patients | Incidence | Ischemia | Electrocardiography | Infarction | Index Medicus
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6. Full Text Infection with the Lyme disease pathogen suppresses innate immunity in mice with diet‐induced obesity
by Zlotnikov, Nataliya and Javid, Ashkan and Ahmed, Mijhgan and Eshghi, Azad and Tang, Tian Tian and Arya, Anoop and Bansal, Anil and Matar, Fatima and Parikh, Maitry and Ebady, Rhodaba and Koh, Adeline and Gupta, Nupur and Song, Peng and Zhang, Yang and Newbigging, Susan and Wormser, Gary P and Schwartz, Ira and Inman, Robert and Glogauer, Michael and Moriarty, Tara J
Cellular microbiology, ISSN 1462-5814, 05/2017, Volume 19, Issue 5, pp. e12689 - n/a
Lyme disease | diseases | Borrelia burgdorferi | infection | host obesity | immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Cell Biology | Borrelia burgdorferi - immunology | Obesity - immunology | Mice, Inbred C57BL | Neutrophils - immunology | Diet, High-Fat - adverse effects | Immune Tolerance | Male | Lyme Disease - pathology | Immunity, Innate | Obesity - microbiology | Mice, Inbred C3H | Lyme Disease - immunology | Animals | Female | Obesity - etiology | Neutrophils - microbiology | Myocarditis - immunology | Macrophages - immunology | Macrophages - microbiology | Myocarditis - microbiology | Cytokines - blood | Medicine, Experimental | Obesity | Medical research | Health aspects | Index Medicus
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7. Full Text Disease model discovery from 3,328 gene knockouts by the International Mouse Phenotyping Consortium
by Meehan, Terrence F and Conte, Nathalie and West, David B and Jacobsen, Julius O and Mason, Jeremy and Warren, Jonathan and Chen, Chao-Kung and Tudose, Ilinca and Relac, Mike and Matthews, Peter and Karp, Natasha and Santos, Luis and Fiegel, Tanja and Ring, Natalie and Westerberg, Henrik and Greenaway, Simon and Sneddon, Duncan and Morgan, Hugh and Codner, Gemma F and Stewart, Michelle E and Brown, James and Horner, Neil and Haendel, Melissa and Washington, Nicole and Mungall, Christopher J and Reynolds, Corey L and Gallegos, Juan and Gailus-Durner, Valerie and Sorg, Tania and Pavlovic, Guillaume and Bower, Lynette R and Moore, Mark and Morse, Iva and Gao, Xiang and Tocchini-Valentini, Glauco P and Obata, Yuichi and Cho, Soo Young and Seong, Je Kyung and Seavitt, John and Beaudet, Arthur L and Dickinson, Mary E and Herault, Yann and Wurst, Wolfgang and De Angelis, Martin Hrabe and Kent Lloyd, K.C and Flenniken, Ann M and Nutter, Lauryl M J and Newbigging, Susan and McKerlie, Colin and Justice, Monica J and Murray, Stephen A and Svenson, Karen L and Braun, Robert E and White, Jacqueline K and Bradley, Allan and Flicek, Paul and Wells, Sara and Skarnes, William C and Adams, David J and Parkinson, Helen and Mallon, Ann-Marie and Brown, Steve D.M and Smedley, Damian and Int Mouse Phenotyping Consortium and International Mouse Phenotyping Consortium and The International Mouse Phenotyping Consortium
Nature genetics, ISSN 1061-4036, 08/2017, Volume 49, Issue 8, pp. 1231 - 1238
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetic Predisposition to Disease | Phenotype | Animals | Humans | Female | Genetic Diseases, Inborn | Male | Mice | Gene Knockout Techniques | Disease Models, Animal | Mice, Knockout | Usage | Genetic aspects | Research | Animal models in research | Genomics | Heart | Animal models | Ontology | Disease | Genes | Disorders | Genomes | Statistical methods | Gene sequencing | Consortia | Signal transduction | Annotations | Databases | Rodents | Right ventricular dysplasia | Automation | Gene expression | Ventricular dysplasia | Diseases | Studies | Acids | Phenotyping | Diagnostic systems | Mutation | Ventricle | Index Medicus
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8. Full Text Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen
by Adissu, Hibret A and Estabel, Jeanne and Sunter, David and Tuck, Elizabeth and Hooks, Yvette and Carragher, Damian M and Clarke, Kay and Karp, Natasha A and Newbigging, Susan and Jones, Nora and Morikawa, Lily and White, Jacqueline K and McKerlie, Colin and Sanger Mouse Genetics Project
Disease models & mechanisms, ISSN 1754-8403, 2014, Volume 7, Issue 5, pp. 515 - 524
Pathology | Histopathology | Mouse | High-throughput phenotyping | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Phenotype | Animals | Alleles | Female | Male | Mice | Organ Specificity | High-Throughput Screening Assays - methods | Mice, Knockout | Index Medicus
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9. Full Text Genome-wide screening of mouse knockouts reveals novel genes required for normal integumentary and oculocutaneous structure and function
by Moore, Bret A and Flenniken, Ann M and Clary, Dave and Moshiri, Ata S and Nutter, Lauryl M. J and Berberovic, Zorana and Owen, Celeste and Newbigging, Susan and Adissu, Hibret and Eskandarian, Mohammad and McKerlie, Colin and Thomasy, Sara M and Lloyd, K. C. Kent and Murphy, Christopher J and Moshiri, Ala and Brown, Steve and Wells, Sara and Mallon, Ann-Marie and Beaudet, Arthur L and de Angelis, Martin Hrabe and Karp, Natasha and Braun, Bob and Herault, Yann and Gao, Xiang and Obata, Yuichi and Flicek, Paul and Meehan, Terrence and Parkinson, Helen and Smedley, Damian and Seong, J. K and Tocchini-Valentini, Glauco and Mammano, Fabio and Int Mouse Phenotyping Consortium and International Mouse Phenotyping Consortium
Scientific reports, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11211 - 9
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phenotypes | Animal models | Albinism | Therapeutic applications | Genes | Rodents | Phenotyping | Genomes | Mutation | Gene deletion | Integument | Structure-function relationships | Index Medicus
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