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Journal of Canadian Studies/Revue d'études canadiennes, ISSN 0021-9495, 2018, Volume 52, Issue 2, pp. 427 - 450
In exploratory research, we investigate whether a recently developed framework of leader character, grounded in the business administration literature, has any... 
Leadership | Canada | Evaluation | Trudeau, Justin | Clinton, Hillary Rodham | Reputation | Public opinion | Trump, Donald | 1946 | Political leadership | Perception | Politics | Character | Canadian | politics | character | POLITICAL-LEADERSHIP | IMAGES | PERFORMANCE | leadership | ELECTION | TRUST | HUMANITIES, MULTIDISCIPLINARY | perception
Journal Article
Journal of Canadian Studies, ISSN 0021-9495, 04/2018, Volume 52, Issue 2, p. 427
In exploratory research, we investigate whether a recently developed framework of leader character, grounded in the business administration literature, has any... 
Politicians | Candidates | Populism | Public opinion surveys | Personality | Political leadership | Prime ministers | Political culture | Leaders | Presidential elections | Personality traits | Voters | Politics | Presidents | Canadian studies
Journal Article
Journal Article
Nature, ISSN 0028-0836, 05/2017, Volume 545, Issue 7652, pp. 48 - 53
Journal Article
by Martin, Miguel and Holmes, Frankie A and Ejlertsen, Bent and Delaloge, Suzette and Moy, Beverly and Iwata, Hiroji and von Minckwitz, Gunter and Chia, Stephen K L and Mansi, Janine and Barrios, Carlos H and Gnant, Michael and Tomašević, Zorica and Denduluri, Neelima and Šeparović, Robert and Gokmen, Erhan and Bashford, Anna and Ruiz Borrego, Manuel and Kim, Sung-Bae and Jakobsen, Erik Hugger and Ciceniene, Audrone and Inoue, Kenichi and Overkamp, Friedrich and Heijns, Joan B and Armstrong, Anne C and Link, John S and Joy, Anil Abraham and Bryce, Richard and Wong, Alvin and Moran, Susan and Yao, Bin and Xu, Feng and Auerbach, Alan and Buyse, Marc and Chan, Arlene and Harvey, Vernon and Tomek, Rudolf and Robert, Nicholas J and Gore, Ira and Smith, John W and Masuda, Norikazu and Di Sean Kendall, S and Harker, William Graydon and Petrakova, Katarina and Guerrero Zotano, Angel and Simon, Amparo Ruiz and Konstantinovic, Zora Neskovic and Iannotti, Nicholas O and Tassone, Pierfrancesco and Rodriguez, Gladys I and Jáñez Martinez, Noelia and Crespo Massieu, Carmen and Smickoska, Snezana and Somali, Isil and Yilmaz, Ugur and Alonso, Mirta Garcia and Rosales, Adolfo Murias and Cold, Soeren and Knoop, Ann Soegaard and Patt, Debra and Hellerstedt, Beth A and Morales Murillo, Serafin and Mayer, Ingrid A and Means-Powell, Julie Ann and Hui, Rina and Senecal, Francis M and De Boer, Richard Hendry and Shen, Zhenzhou and Luczak, Adam Andrzej and Chui, Joanna W.Y and Tsang, Janice Wing-hang and Lang, Istvan and Rai, Yoshiaki and Hozumi, Yasuo and Ten Tije, Albert J and Bhandari, Manish and Osborne, Cynthia R.C and Ohtani, Shoichiro and Higaki, Kenji and Watanabe, Kenichi and Taguchi, Kazunori and Takahashi, Masato and Filipovic, Sladjana and Hansen, Vincent L and Rao, Vijayarama Phooshkooru and Gupta, Manish and Petrov, Petar and Coudert, Bruno and Vojnovic, Zeljko and Polya, Zsofia and Miyaki, Toshiko and Yamamoto, Naohito and Brincat, Stephen and Lesniewski-Kmak, Krzysztof and Chmielowska, Ewa and Birhiray, Ruemu E and Citron, Marc L and Papish, Steven William and Berry, William R and Langkjer, Sven Tyge and Garcia Sáenz, José Angel and ... and ExteNET Study Group and ExteNET Study Grp
The Lancet Oncology, ISSN 1470-2045, 12/2017, Volume 18, Issue 12, pp. 1688 - 1700
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0158674
Modeling clinically relevant tissue responses using cell models poses a significant challenge for drug development, in particular for drug induced liver injury... 
SYSTEM | HEPATOCYTES | IDIOSYNCRASY | HEPATIC STELLATE CELLS | MULTIDISCIPLINARY SCIENCES | INJURY | LIPOPOLYSACCHARIDE | TROVAFLOXACIN HEPATOTOXICITY | CULTURE | RELEVANT | Bioprinting | Cell Proliferation | Albumins - metabolism | Humans | Liver - metabolism | Cells, Cultured | Lipopolysaccharides - metabolism | Hepatocytes - metabolism | Chemical and Drug Induced Liver Injury - diagnosis | Hepatocytes - cytology | Image Processing, Computer-Assisted | Liver - drug effects | Cytochrome P-450 CYP3A - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Drug-Related Side Effects and Adverse Reactions | Cell Culture Techniques | Imaging, Three-Dimensional | Naphthyridines - administration & dosage | Hepatocytes - drug effects | Levofloxacin - administration & dosage | Fluoroquinolones - administration & dosage | Drugs | Usage | Liver | Models | Diagnosis | Health aspects | 3D printing | Cytochrome | Cell culture | Levofloxacin | Enzyme activity | Toxicity | Smooth muscle | Research | Drug development | Macrophages | Mimicry | Toxicology | Enzymatic activity | Metabolites | Actin | Rodents | Biocompatibility | Physiology | Drug therapy | Trovafloxacin | Architecture | Tissue engineering | Muscles | Antimicrobial agents | Metabolism | Gene expression | Desmin | Three dimensional printing | Inventors | Hepatocytes | Human behavior | Three dimensional models | Pharmaceuticals
Journal Article
Nature, ISSN 0028-0836, 12/2017, Volume 552, Issue 7684, pp. 253 - 257
Tissue-resident memory CD8(+) T (T-RM) cells are found at common sites of pathogen exposure, where they elicit rapid and robust protective immune... 
TRANSCRIPTION FACTORS | LUNG-CANCER | POPULATION | MEMORY | RNA-SEQ | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | CD4(+) | INFECTION | DIFFERENTIATION | EXPRESSION | T-Lymphocyte Subsets - immunology | CD8-Positive T-Lymphocytes - cytology | Chromatin - metabolism | Core Binding Factor Alpha 3 Subunit - metabolism | Cell Proliferation | T-Lymphocyte Subsets - cytology | Humans | Homeostasis | Male | Adoptive Transfer | Organ Specificity - immunology | Organ Specificity - genetics | Melanoma - genetics | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Cell Differentiation | Disease Models, Animal | Gene Expression Regulation | Melanoma - pathology | Animals | Core Binding Factor Alpha 3 Subunit - deficiency | Lymphocytes, Tumor-Infiltrating - pathology | Melanoma - immunology | T-Lymphocyte Subsets - metabolism | Survival Analysis | Core Binding Factor Alpha 3 Subunit - genetics | Immunologic Memory | Mice | CD8-Positive T-Lymphocytes - immunology | Melanoma - therapy | Chromatin - genetics | Physiological aspects | T cells | Tumors | Chromatin | Transcription factors | CD8 antigen | Genes | Lung cancer | Cytotoxicity | Systematic review | Lymphocytes T | Tissues | Lymphocytes | Immunological memory | Cell survival | Immune response | RNA-mediated interference | Melanoma | Principal components analysis | T cell receptors | Lymphoid tissue | Cell differentiation | Gene expression | Ribonucleic acid--RNA | Runx3 protein | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e81689
Here, we describe an engineering approach to quantitatively compare migration, morphologies, and adhesion for tumorigenic human fibrosarcoma cells (HT-1080s)... 
SIGNALING PATHWAYS | CANCER INVASION | FOCAL ADHESION | MULTIDISCIPLINARY SCIENCES | CYTOSKELETAL ORGANIZATION | GENE-EXPRESSION | CORTICAL FLOW | P34CDC2 KINASE | AGGRESSIVE TUMOR-GROWTH | SOMATIC MUTATIONS | COLLAGEN SUBSTRATA | Gene Expression | Hydrogels | Humans | Actins - metabolism | Vinculin - metabolism | CD146 Antigen - genetics | Fibroblasts - pathology | Cell Adhesion | Cell Movement - genetics | Extracellular Matrix - chemistry | Actins - genetics | Integrin beta1 - metabolism | Molecular Mimicry | Phenotype | CD146 Antigen - metabolism | Vinculin - genetics | Cell Transformation, Neoplastic | Matrix Metalloproteinases - chemistry | Cell Line, Tumor | Cell Culture Techniques | Primary Cell Culture | Integrin beta1 - genetics | Fibroblasts - metabolism | Care and treatment | Cancer cells | Physiological aspects | Fibroblasts | Fibrosarcoma | Research | Diagnosis | Comparative analysis | Bioengineering | Self assembly | Transformation | Motility | Materials science | Biology | Metastasis | Matrix metalloproteinase | Kinases | Contraction | Cell adhesion & migration | Cell adhesion molecules | Proteins | Engineering | Genotype & phenotype | Adhesive strength | Filaments | Polyethylene glycol | Proteolysis | Actin | Cell adhesion | Extracellular matrix | Metalloproteinase | Biomedical engineering | Actomyosin | Melanoma | Cortex | Contractility | Rounding | Adhesion | Studies | Properties (attributes) | Researchers | Vinculin | Morphology | Collagen | Cytoskeleton | Skin | Science programs | Mutation | Cell migration | Tumors | Cancer | Tips
Journal Article