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Journal Article
PLoS ONE, ISSN 1932-6203, 07/2018, Volume 13, Issue 7, p. e0200611
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 10/2018, Volume 59, Issue 10, pp. 1558 - 1565
Imaging biomarkers must demonstrate their value in monitoring treatment. Two PET tracers, the caspase-3/7–specific isatin-5-sulfonamide 18 F-ICMT-11 ( 18 F-( S... 
Proliferation | PET imaging | Anti-EGFR-based therapy | Apoptosis | anti-EGFR-based therapy | Oncology | apoptosis | proliferation
Journal Article
FASEB Journal, ISSN 0892-6638, 06/2004, Volume 18, Issue 9, pp. 1016 - 1018
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 05/2019, Volume 16, Issue 5, pp. 2106 - 2117
In humans, C–X–C chemokine receptor type 4 (CXCR4) is a protein that is encoded by the CXCR4 gene and binds the ligand CXCL12 (also known as SDF-1). The... 
Index Medicus | AMD3465 | CXCR4 | [18F]MCFB | cyclam
Journal Article
Journal Article
Chemical Communications, ISSN 1359-7345, 08/2014, Volume 50, Issue 67, pp. 9557 - 9560
Herein, we describe a fast and robust method for achieving 68Ga-labelling of the EGFR-selective monoclonal antibody (mAb) Cetuximab using the bioorthogonal... 
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, p. e44160
Anti-estrogens, in particular tissue selective anti-estrogens, have been the bedrock of adjuvant therapy for patients with estrogen receptor alpha (ER alpha)... 
SERUM TAMOXIFEN CONCENTRATIONS | CANCER PATIENTS | HORMONE-RECEPTORS | SURGICAL ADJUVANT BREAST | CONFORMATIONAL-CHANGES | NUCLEAR RECEPTORS | MULTIDISCIPLINARY SCIENCES | POSTMENOPAUSAL WOMEN | FRAGMENT-ASSISTED COMPLEMENTATION | ATHYMIC NUDE-MOUSE | LUCIFERASE | Estradiol - analogs & derivatives | Estrogens - pharmacology | Luciferases - metabolism | Humans | Imaging, Three-Dimensional - methods | Genetic Complementation Test | Recombinant Fusion Proteins - metabolism | Fulvestrant | Nuclear Receptor Coactivator 3 - chemistry | Time Factors | Protein Binding - drug effects | Estrogen Receptor alpha - metabolism | Female | Estradiol - pharmacology | Genes, Reporter | Protein Structure, Tertiary | Estrogen Receptor alpha - chemistry | Protein Structure, Secondary | Mutation - genetics | Estrogen Receptor Modulators - pharmacology | Animals | Nuclear Receptor Coactivator 3 - metabolism | Tamoxifen - pharmacology | Tamoxifen - analogs & derivatives | Biosensing Techniques - methods | Mice | Mice, Inbred BALB C | Physiological aspects | Receptors | Genetic aspects | Research | Protein-protein interactions | Estrogen | Transcription factors | Estrogens | Estrogen receptors | Breast cancer | Gene expression | Bedrock | Cancer therapies | Mutants | Recruitment | Proteins | Imaging | Ligands | Bone density | Hormone replacement therapy | Protein interaction | Fusion protein
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2014, Volume 9, Issue 7, p. e101366
Background: 3'-Deoxy-3'-[F-18]-fluorothymidine ([F-18] FLT) is being investigated as a Positron Emission Tomography (PET) proliferation biomarker. The... 
BREAST-CANCER | CELLS | POSITRON-EMISSION-TOMOGRAPHY | MULTIDISCIPLINARY SCIENCES | IN-VIVO | TUMOR | VALIDATION | DEGRADATION | PROLIFERATION | MITOTIC PHOSPHORYLATION | 3'-DEOXY-3'-FLUOROTHYMIDINE PET | Dideoxynucleosides - metabolism | Osteosarcoma - drug therapy | Phosphorylation | Bone Neoplasms - enzymology | Cell Proliferation | Osteosarcoma - enzymology | Colonic Neoplasms - drug therapy | Humans | Fluorodeoxyglucose F18 - metabolism | Bone Neoplasms - pathology | Blotting, Western | Radiopharmaceuticals - metabolism | Cell Cycle | Colonic Neoplasms - pathology | Thymidine Kinase - metabolism | Antineoplastic Agents - pharmacology | Colonic Neoplasms - enzymology | Protein Processing, Post-Translational | Bone Neoplasms - drug therapy | Tumor Cells, Cultured | Antimetabolites - metabolism | Osteosarcoma - pathology | Post-translational modification | Enzymes | PET imaging | Colorectal cancer | Residues | Transcription | Mitosis | Emission analysis | Amino acids | Biology | Thymidine | Catalytic activity | Kinases | Retention | Anticancer properties | Proteins | Cell growth | Antitumor agents | Colon cancer | Transfection | Surgery | Cell cycle | Post-translation | Tomography | Colon | Catalysis | Deoxyribonucleic acid--DNA | Thymidine kinase | Immunoglobulins | Medical imaging | Gels | Gel electrophoresis | Positron emission | Cell division | Fluorine isotopes | Breast cancer | Biological activity | Chemistry | Acids | Plasmids | Biomarkers | Protein expression | Positron emission tomography | Deoxyribonucleic acid | DNA
Journal Article
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 11/2014, Volume 148, Issue 2, pp. 455 - 462
Journal Article
Journal of Nuclear Medicine, ISSN 0161-5505, 09/2014, Volume 55, Issue 9, pp. 1506 - 1512
Deregulated cellular metabolism is a hallmark of many cancers. In addition to increased glycolytic flux, exploited for cancer imaging with (18)F-FDG, tumor... 
FDG | FPIA | Lipid metabolism | PET | Tumor detection | Animals | Humans | Pentanoic Acids | Cell Line, Tumor | Mice | Positron-Emission Tomography | Fluorine Radioisotopes | Radiopharmaceuticals | Neoplasms, Experimental - diagnostic imaging
Journal Article
The FASEB Journal, ISSN 0892-6638, 01/2003, Volume 17, Issue 1, pp. 7 - 16
ABSTRACT We previously established that the trefoil peptides (TFFs) pS2, spasmolytic polypeptide, and intestinal trefoil factor are involved in cellular... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | CELLULAR INVASION | NEUROENDOCRINE DIFFERENTIATION | HUMAN CANCER-CELLS | CELL BIOLOGY | BIOLOGY | GENE-EXPRESSION | SEMAPHORIN-III | TYROSINE KINASE INHIBITOR | FAMILIAL ADENOMATOUS POLYPOSIS | UP-REGULATION | COLONIC EPITHELIAL-CELLS | ENDOTHELIAL GROWTH-FACTOR | Endothelium, Vascular - cytology | Cyclooxygenase 2 | Humans | Endothelium, Vascular - drug effects | Neuropeptides | Nitrobenzenes - pharmacology | Morphogenesis | Muscle Proteins | Receptor, Epidermal Growth Factor - metabolism | Isoenzymes - metabolism | Allantois - drug effects | Trefoil Factor-3 | Chorion - drug effects | Allantois - blood supply | Angiogenesis Inducing Agents - pharmacology | Trefoil Factor-2 | Signal Transduction | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chorion - blood supply | Endothelium, Vascular - growth & development | Sulfonamides - pharmacology | Capillaries - growth & development | Chick Embryo | Cyclooxygenase Inhibitors - pharmacology | Peptides - pharmacology | Membrane Proteins | Animals | Cyclooxygenase 2 Inhibitors | Capillaries - cytology | Prostaglandin-Endoperoxide Synthases - metabolism | Mucins | Growth Substances - pharmacology | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Quinazolines - pharmacology | Isoenzymes - antagonists & inhibitors | Neovascularization, Physiologic
Journal Article