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IMMUNITY, ISSN 1074-7613, 07/2015, Volume 43, Issue 1, pp. 15 - 28
When type III interferon (IFN-lambda; also known as interleukin-28 [IL-28] and IL-29) was discovered in 2003, its antiviral function was expected to be... 
IFN-LAMBDA | SIGNAL-TRANSDUCTION | NOROVIRUS INFECTION | III INTERFERON | DIFFERENTIAL EXPRESSION | STIMULATED GENES | CHRONIC HEPATITIS-C | SUSCEPTIBILITY LOCI | ANTIVIRAL ACTIVITY | IMMUNOLOGY | GENOME-WIDE ASSOCIATION
Journal Article
IMMUNITY, ISSN 1074-7613, 05/2017, Volume 46, Issue 5, pp. 768 - 770
Type III interferon (IFN lambda) and type I IFN (IFN alpha/beta) have overlapping antiviral activities in the lung. In this issue of Immunity, Galani et al.... 
IMMUNOLOGY
Journal Article
SCIENCE, ISSN 0036-8075, 01/2015, Volume 347, Issue 6219, pp. 266 - 269
The capacity of human norovirus (NoV), which causes >90% of global epidemic nonbacterial gastroenteritis, to infect a subset of people persistently may... 
PATHOGENESIS | CELLS | TRANSMISSION | III INTERFERON | VIRUS | REPLICATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | HOST-DEFENSE | VIRAL-INFECTION | Immune systems | Intestines | Antibiotics | Replenishment | Bacteria | Replication | Viruses | Mice
Journal Article
SCIENCE, ISSN 0036-8075, 01/2015, Volume 347, Issue 6219, pp. 269 - 273
Norovirus gastroenteritis is a major public health burden worldwide. Although fecal shedding is important for transmission of enteric viruses, little is known... 
RESPONSES | VIRUS | REPLICATION | PROTEIN | COMMUNITY | MULTIDISCIPLINARY SCIENCES | ANTIVIRAL ACTIVITY | PREVALENCE | SUFFICIENT | NOSOCOMIAL TRANSMISSION | CHILDREN | Proteins | Cytokines | Bacteria | Viruses | Cures | Mice | Immunity | Public health
Journal Article
Journal Article
Trends in Microbiology, ISSN 0966-842X, 06/2018, Volume 26, Issue 6, pp. 510 - 524
Journal Article
SCIENCE, ISSN 0036-8075, 08/2014, Volume 345, Issue 6196, pp. 578 - 582
The mammalian intestine is colonized by beneficial commensal bacteria and is a site of infection by pathogens, including helminth parasites. Helminths induce... 
MICROFLORA | INFECTIONS | BACTERIA | IMMUNE-RESPONSES | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | COMMENSAL MICROBIOTA | CHITINASE | GUT MICROBIOTA | PANETH CELLS | YM1 | Microbiota (Symbiotic organisms) | Physiological aspects | Research | Health aspects | Immunity | Helminthiasis | Immunological research | Parasitology | Immunology | Microbiology | Virology | Immune systems | Pathogens | Viruses | Mice | Parasites | Worms | Flavours | Containment
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 10/2017, Volume 47, Issue 4, pp. 723 - 738.e5
Noroviruses can establish chronic infections with active viral shedding in healthy humans but whether persistence is associated with adaptive immune... 
T cell exhaustion | tissue-resident memory T cells | T cell inflation | norovirus | enteric viral persistence | tissue-resident memory T cells | ACTIVATION | REPLICATION | MEMORY | RESIDENT | GENES | CYTOMEGALOVIRUS-INFECTION | ABSENCE | COSTIMULATION | IMMUNOLOGY | EXHAUSTION | REVEALS | Caliciviridae Infections - virology | Caliciviridae Infections - genetics | Humans | Gastroenteritis - virology | Host-Pathogen Interactions - immunology | Cell Differentiation - genetics | HEK293 Cells | CD8-Positive T-Lymphocytes - metabolism | Gastroenteritis - immunology | Caliciviridae Infections - immunology | Gene Ontology | Immunologic Memory - genetics | Immunologic Memory - immunology | Norovirus - physiology | Cell Line | Oligonucleotide Array Sequence Analysis - methods | Mice, Inbred C57BL | Gene Expression Profiling - methods | Norovirus - immunology | Cellular Microenvironment - immunology | Cell Differentiation - immunology | Animals | CD8-Positive T-Lymphocytes - virology | Gastroenteritis - genetics | Cellular Microenvironment - genetics | CD8-Positive T-Lymphocytes - immunology | Shedding | Antigens | Cytomegalovirus | Immunological memory | Memory cells | CD8 antigen | Differentiation (biology) | Chronic infection | Viruses | Infections | Lymphocytes T | T cell receptors | Cell differentiation | Cells | Studies | Lymphocytes | Exhaustion | Replication | Immune privilege | Genetic engineering | Immune system | Norovirus
Journal Article
Cell host & microbe, ISSN 1931-3128, 11/2018, Volume 24, Issue 5, pp. 665 - 676
Journal Article
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, ISSN 0887-3585, 07/2014, Volume 82, Issue 7, pp. 1200 - 1209
Compact viral genomes such as those found in noroviruses, which cause significant enteric disease in humans, often encode only a few proteins, but affect a... 
SYSTEM | protein NMR | CELLS | COMPLEX | PEST motif | SEQUENCES | helix-strand-helix | BIOCHEMISTRY & MOLECULAR BIOLOGY | side chain rotamers | NORWALK-LIKE VIRUS | ORGANIZATION | NMR | BIOPHYSICS | MNV | BIOLOGY | NONSTRUCTURAL PROTEIN | polyprotein
Journal Article
Journal of virology, ISSN 0022-538X, 12/2018, Volume 92, Issue 23
The linear ubiquitin chain assembly complex (LUBAC), composed of heme-oxidized IRP2 ubiquitin ligase 1 (HOIL1), HOIL1-interacting protein (HOIP), and... 
interferons | HOIL1 | norovirus | ubiquitination | LUBAC | MDA5 | LINEAR UBIQUITINATION | RIG-I | RNA VIRUSES | TOLL-LIKE RECEPTOR-3 | ADAPTIVE IMMUNITY | INNATE IMMUNE RECOGNITION | VIROLOGY | LUBAC DEFICIENCY | NF-KAPPA-B | ANTIVIRAL IMMUNITY | E3 UBIQUITIN LIGASE
Journal Article