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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, ISSN 1433-7851, 09/2014, Volume 53, Issue 40, pp. 10714 - 10717
The widespread application of omega-transaminases as biocatalysts for chiral amine synthesis has been hampered by fundamental challenges, including unfavorable... 
chiral amines | ASYMMETRIC-SYNTHESIS | MANUFACTURE | high-throughput screening | DERACEMIZATION | transaminases | CASCADE | asymmetric catalysis | CHEMISTRY, MULTIDISCIPLINARY | biocatalysis | KETONES | EVOLUTION | OXIDASE | REDUCTION | EFFICIENT | Screening | Diamines | Synthesis | Amines | Equivalence | Byproducts | Derivatives | Conversion | Displacement
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 12/2018, Volume 57, Issue 51, pp. 16760 - 16763
Herein we report the biocatalytic synthesis of substituted pyrazines and pyrroles using a transaminase (ATA) to mediate the key amination step of the ketone... 
pyrazine | biocatalysis | nitrogen heterocycles | ω-transaminase | pyrrole | ENANTIOSELECTIVE SYNTHESIS | TRANSAMINASE | omega-transaminase | CHEMISTRY, MULTIDISCIPLINARY | Enzymes | Chemotherapy | Amines | Catalysis | Ketones | Cancer | Substitutes | Enzymatic synthesis | Pyrazines | Diketones | Synthesis | Amination | Transaminase | Pyrroles | Esters | Dimerization | Communications | Communication
Journal Article
2017, 2nd ed. 2017., ISBN 3319582445
Published in 2014,  Protein Deimination in Human Health and Disease  was the first book on this novel post-translational modification, in which selected... 
Medicine | Proteins | Neurosciences | Immunology
Web Resource
2017, 2nd ed. 2017., ISBN 3319582445
Published in 2014,  Protein Deimination in Human Health and Disease  was the first book on this novel post-translational modification, in which selected... 
Medicine | Proteins | Neurosciences | Immunology
Web Resource
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2013, Volume 110, Issue 17, pp. 6626 - 6633
Journal Article
British journal of pharmacology, 02/2019
Apelin is an endogenous vasodilatory and inotropic peptide that is down-regulated in human pulmonary arterial hypertension, although the density of the apelin... 
Journal Article
by Lee, Shermin and Ripke, S and Neale, B.M and Faraone, S.V and Purcell, S.M and Perlis, R.H and Mowry, B.J and Thapar, A and Goddard, M.E and Witte, J.S and Absher, D and Agartz, I and Akil, H and Amin, F and Aneassen, O.A and Anjorin, A and Anney, R and Anttila, V and Arking, D.E and Asherson, P and Azevedo, M.H and Backlund, L and Badner, J.A and Bailey, A.J and Banaschewski, T and Barchas, J.D and Barnes, M.R and Barrett, T.B and Bass, N and Battaglia, A and Bauer, M and Bayes, M and Bellivier, F and Bergen, S.E and Berrettini, W and Betancur, C and Bettecken, T and Biederman, J and Binder, E.B and Black, D.W and Blackwood, D.H and Bloss, C.S and Boehnke, M and Boomsma, D.I and Breen, G and Breuer, R and Bruggeman, R and Cormican, P and Buccola, N.G and Buitelaar, J.K and Bunney, W.E and Buxbaum, J.D and Byerley, W.F and Byrne, E.M and Caesar, S and Cahn, W and Cantor, R.M and Casas, M and Chakravarti, A and Chambert, K and Choudhury, K and Cichon, S and Cloninger, C.R and Collier, D.A and Cook, E.H and Coon, H and Cormand, B and Corvin, A and Coryell, W.H and Craig, D.W and Craig, I.W and Crosbie, J and Cuccaro, M.L and Curtis, D and Czamara, D and Datta, S and Dawson, G and Day, R and Geus, E.J. de and Degenhardt, F and Djurovic, S and Donohoe, G.J and Doyle, A.E and Duan, J and Dudbridge, F and Duketis, E and Ebstein, R.P and Edenberg, H.J and Elia, J and Ennis, S and Etain, B and Fanous, A and Farmer, A.E and Ferrier, I.N and Flickinger, M and Fombonne, E and Foroud, T and Frank, J and Franke, B and et al and Cross-Disorder Grp Psychiat Genomi and Int Inflammatory Bowel Dis Genetic and Cross-Disorder Group of the Psychiatric Genomics Consortium
Nature Genetics, ISSN 1061-4036, 2013, Volume 45, Issue 9, pp. 984 - 994
Most psychiatric disorders are moderately to highly heritable. The degree to which genetic variation is unique to individual disorders or shared across... 
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | CROHNS-DISEASE | DEFICIT HYPERACTIVITY DISORDER | COMMON SNPS | GENETICS & HEREDITY | SCHIZOPHRENIA | RISK | AUTISM SPECTRUM DISORDERS | BIPOLAR DISORDER | ASSOCIATION | HERITABILITY | Usage | Genetic aspects | Research | Single nucleotide polymorphisms | Psychoses | Genomics | Life Sciences | Biochemistry, Molecular Biology
Journal Article
Ophthalmology, ISSN 0161-6420, 2014, Volume 121, Issue 8, pp. 1501 - 1507
Journal Article
01/2017, 2 ed., ISBN 3319582437, 467
Published in 2014, Protein Deimination in Human Health and Disease was the first book on this novel post-translational modification, in which selected... 
Proteins | Chemical modification | Protein Science | Neurosciences | Biomedicine | Immunology
eBook
Developmental and Comparative Immunology, ISSN 0145-305X, 10/2018, Volume 87, p. 1
Pentraxins are fluid phase pattern recognition molecules that form an important part of the innate immune defence and are conserved between fish and human. In... 
Immune response | Hatching | Liver | Mucosa | Nervous system | Mucus | Ontogeny | Pattern recognition | Citrulline | Remodeling | Tissues | Proteins | Arginine | Post-translation | Fish | Skin | Amyloidosis | CRP protein | Autoimmune diseases | Pentraxins | Cancer | Immune system
Journal Article
Angewandte Chemie, ISSN 1433-7851, 09/2014, Volume 53, Issue 40, p. 10714
  The widespread application of [omega]-transaminases as biocatalysts for chiral amine synthesis has been hampered by fundamental challenges, including... 
Research & development--R&D
Journal Article