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Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1368 - 12
Formate overflow coupled to mitochondrial oxidative metabolism\has been observed in cancer cell lines, but whether that takes place in the tumor... 
GLYCINE | ONCOGENE | METABOLISM | MTHFD2 | EXPRESSION | MULTIDISCIPLINARY SCIENCES | Methotrexate - pharmacology | Intestinal Mucosa - metabolism | Adenoma - genetics | Gene Expression Regulation, Neoplastic | Mammary Glands, Animal - virology | Male | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Adenoma - metabolism | Isoenzymes - metabolism | Antimetabolites, Antineoplastic - pharmacology | Female | Mammary Tumor Virus, Mouse - pathogenicity | Intestinal Neoplasms - genetics | Formates - metabolism | Mammary Neoplasms, Experimental - drug therapy | Tumor Microenvironment - drug effects | Glycine Hydroxymethyltransferase - genetics | Intestines - pathology | Oxidation-Reduction | Isoenzymes - genetics | Mammary Glands, Animal - pathology | Intestinal Neoplasms - metabolism | Mice, Inbred C57BL | Mitochondria - metabolism | Mitochondria - drug effects | Glycine Hydroxymethyltransferase - metabolism | Serine - metabolism | Intestinal Neoplasms - pathology | Animals | Mammary Glands, Animal - metabolism | Formates - pharmacology | Adenoma - pathology | Cell Line, Tumor | Mice | Mammary Neoplasms, Experimental - virology | Phenotypes | Animal models | Oxidative metabolism | Serine | Tumor cell lines | Metabolism | Overflow | Mitochondria | Intestine | Cell lines | Catabolism | Mammary gland | Cancer
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2019, Volume 10, Issue 1, pp. 1787 - 16
The identity and unique capacity of cancer stem cells (CSC) to drive tumor growth and resistance have been challenged in brain tumors. Here we report that... 
INITIATING CELLS | SIDE POPULATION | THERAPY | SUBTYPES | MULTIDISCIPLINARY SCIENCES | IDENTIFICATION | HYPOXIA | EXPRESSION | CD133 | HIERARCHY | REVEALS | Brain | Brain tumors | Brain cancer | Glioblastoma | Cell membranes | Epitopes | Heterogeneity | Plasticity | Stem cells | Plastic properties | Mathematical models | Tumors | Cancer
Journal Article
EMBO reports, ISSN 1469-221X, 11/2018, Volume 19, Issue 11, p. n/a
Journal Article
Brain Pathology, ISSN 1015-6305, 07/2019, Volume 29, Issue 4, pp. 513 - 529
Journal Article
RNA, ISSN 1355-8382, 11/2014, Volume 20, Issue 11, pp. 1655 - 1665
The vast majority of the human transcriptome does not code for proteins. Advances in transcriptome arrays and deep sequencing are giving rise to a fast... 
Journal Article
F1000Research, ISSN 2046-1402, 2019, Volume 7, p. 1906
Background: The topological analysis of networks extracted from different types of "omics" data is a useful strategy for characterizing biologically meaningful... 
Medical research | Phenotypes | Genomics | Glioblastoma | Data processing | Tumor cell lines | Gene expression | Experiments | Datasets | Studies | Lymphocytes B | Prediction models | Cell lines | Software | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14 Supplement, pp. LB-308 - LB-308
IDH1 R132H mutations are considered to play a key role in the development of low grade gliomas and therefrom derived secondary glioblastomas (GBM). Wild type... 
Journal Article
RNA, ISSN 1355-8382, 11/2014, Volume 20, Issue 11, pp. 1655 - 1665
Journal Article
Cell Stem Cell, ISSN 1934-5909, 2011, Volume 8, Issue 2, pp. 136 - 147
The “Side Population” (SP) discrimination assay is a flow cytometry method used to detect stem cells based on the dye efflux properties of ABC transporters. We... 
ABCG2 EXPRESSION | RESISTANCE PROTEIN | DYE EFFLUX | BONE-MARROW | IN-VIVO | MOUSE MODEL | NEURAL STEM | BLOOD-BRAIN-BARRIER | DRUG EFFLUX TRANSPORTERS | P-GLYCOPROTEIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neoplastic Stem Cells - cytology | Phenotype | Neoplastic Stem Cells - metabolism | Humans | Ploidies | Stem Cells - cytology | Stem Cells - metabolism
Journal Article
Scientific reports, 05/2016, Volume 6, p. 26822
The zebrafish has the capacity to regenerate its heart after severe injury. While the function of a few genes during this process has been studied, we are far... 
Journal Article
by Waddell, Nicola and Pajic, Marina and Patch, Ann-Marie and Chang, David K and Kassahn, Karin S and Bailey, Peter and Johns, Amber L and Miller, David and Nones, Katia and Quek, Kelly and Quinn, Michael C. J and Robertson, Alan J and Fadlullah, Muhammad Z. H and Bruxner, Tim J. C and Christ, Angelika N and Harliwong, Ivon and Idrisoglu, Senel and Manning, Suzanne and Nourse, Craig and Nourbakhsh, Ehsan and Wani, Shivangi and Wilson, Peter J and Markham, Emma and Cloonan, Nicole and Anderson, Matthew J and Fink, J. Lynn and Holmes, Oliver and Kazakoff, Stephen H and Leonard, Conrad and Newell, Felicity and Poudel, Barsha and Song, Sarah and Taylor, Darrin and Waddell, Nick and Wood, Scott and Xu, Qinying and Wu, Jianmin and Pinese, Mark and Cowley, Mark J and Lee, Hong C and Jones, Marc D and Nagrial, Adnan M and Humphris, Jeremy and Chantrill, Lorraine A and Chin, Venessa and Steinmann, Angela M and Mawson, Amanda and Humphrey, Emily S and Colvin, Emily K and Chou, Angela and Scarlett, Christopher J and Pinho, Andreia V and Giry-Laterriere, Marc and Rooman, Ilse and Samra, Jaswinder S and Kench, James G and Pettitt, Jessica A and Merrett, Neil D and Toon, Christopher and Epari, Krishna and Nguyen, Nam Q and Barbour, Andrew and Zeps, Nikolajs and Jamieson, Nigel B and Graham, Janet S and Niclou, Simone P and Bjerkvig, Rolf and Grützmann, Robert and Aust, Daniela and Hruban, Ralph H and Maitra, Anirban and Iacobuzio-Donahue, Christine A and Wolfgang, Christopher L and Morgan, Richard A and Lawlor, Rita T and Corbo, Vincenzo and Bassi, Claudio and Falconi, Massimo and Zamboni, Giuseppe and Tortora, Giampaolo and Tempero, Margaret A and Gill, Anthony J and Eshleman, James R and Pilarsky, Christian and Scarpa, Aldo and Musgrove, Elizabeth A and Pearson, John V and Biankin, Andrew V and Grimmond, Sean M and Australian Pancreatic Canc Genome and Australian Pancreatic Cancer Genome Initiative
Nature, ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 495 - 501
Journal Article