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Food Chemistry, ISSN 0308-8146, 2010, Volume 122, Issue 3, pp. 662 - 667
Catechins are an important class of dietary flavonoids with promising use as therapeutic agents due to their potent antioxidant activity and diverse biological... 
Encapsulation | Nanoparticles | Catechin | Epigallocatechin gallate | Reducing agents | Stability | ANTIOXIDANTS | FOOD SCIENCE & TECHNOLOGY | CHITOSAN | FLAVONOIDS | ASCORBIC-ACID | CANCER | DELIVERY | NUTRITION & DIETETICS | GREEN TEA CATECHINS | ORAL BIOAVAILABILITY | DEGRADATION | ABSORPTION | CHEMISTRY, APPLIED | Antioxidants | Phosphates | Organic acids | Isoflavones
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 10/2019, Volume 85, Issue 10, pp. 2351 - 2359
Aims Patients with Alzheimer's disease (AD), the most common form of dementia, have reduced P‐glycoprotein (P‐gp) function at the blood–brain barrier. However,... 
pharmacokinetics | p‐glycoprotein | clinical pharmacology | Alzheimer's disease | neurology | therapeutic drug monitoring | Care and treatment | Digoxin | Analysis
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e59749
To assess the role of the kynurenine pathway in the pathology of Alzheimer's disease (AD), the expression and localization of key components of the kynurenine... 
HUMAN NEURONS | HUMAN MICROGLIA | NERVOUS-SYSTEM | CELLS | INHIBITION | INTERFERON-GAMMA | EXCITOTOXIN QUINOLINIC ACID | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | INDOLEAMINE 2,3-DIOXYGENASE | PICOLINIC-ACID | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Humans | Middle Aged | Cerebellum - enzymology | Mice, 129 Strain | Pentosyltransferases - metabolism | RNA, Messenger - metabolism | Carboxy-Lyases - genetics | Tryptophan - metabolism | Case-Control Studies | Aged, 80 and over | Carboxy-Lyases - metabolism | Kynurenine - metabolism | Real-Time Polymerase Chain Reaction | Pentosyltransferases - genetics | CA1 Region, Hippocampal - enzymology | Cerebral Cortex - enzymology | Gene Expression | Mice, Inbred C57BL | RNA, Messenger - genetics | CA3 Region, Hippocampal - enzymology | Mice, Transgenic | Alzheimer Disease - enzymology | Organ Specificity | Tryptophan Oxygenase - metabolism | Tryptophan Oxygenase - genetics | Animals | Metabolic Networks and Pathways | 3-Hydroxyanthranilate 3,4-Dioxygenase - genetics | Aged | Mice | 3-Hydroxyanthranilate 3,4-Dioxygenase - metabolism | Immunohistochemistry | Enzymes | Advertising executives | Brain | Medical research | Metabolites | RNA | Tryptophan | Medicine, Experimental | Genetic engineering | Alzheimer's disease | Cerebellum | Tryptophan 2,3-dioxygenase | mRNA | Picolinic acid | Senile plaques | Neurodegeneration | Rodents | Amyloid | Kynurenic acid | Quinolinic acid | Localization | Discipline | Pharmaceutical sciences | Age | Neurodegenerative diseases | Transgenic mice | Pharmacology | Metabolism | Gene expression | Patients | Pathology | Neurofibrillary tangles | Brain research | Acids | Tau protein | Position (location) | Alzheimers disease | Hippocampus
Journal Article
Pharmaceutical Research, ISSN 0724-8741, 2015, Volume 32, Issue 3, pp. 819 - 839
Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by beta-amyloid plaques and hyperphosphorylated tau tangles in the brain. Alongside... 
blood-brain barrier | tight junctions | transporters | Alzheimer's disease | cerebrovascular basement membrane | P-GLYCOPROTEIN FUNCTION | CEREBRAL AMYLOID ANGIOPATHY | BLOOD-BRAIN-BARRIER | CHEMISTRY, MULTIDISCIPLINARY | NORMAL HUMAN-TISSUES | AGE-RELATED-CHANGES | DIMINISHED GLUCOSE-TRANSPORT | PHARMACOLOGY & PHARMACY | TRANSGENIC MOUSE MODEL | RECEPTOR-RELATED PROTEIN-1 | SPATIAL MEMORY IMPAIRMENT | CANCER RESISTANCE PROTEIN | Central Nervous System Agents - therapeutic use | Capillary Permeability | Humans | tau Proteins - metabolism | Alzheimer Disease - pathology | Brain - metabolism | Brain - blood supply | Plaque, Amyloid | Drug Dosage Calculations | Drug Interactions | Polypharmacy | Biological Transport | Amyloid beta-Peptides - metabolism | Membrane Transport Proteins - metabolism | Tight Junction Proteins - metabolism | Tight Junctions - metabolism | Alzheimer Disease - physiopathology | Alzheimer Disease - drug therapy | Cerebrovascular Circulation | Blood-Brain Barrier - metabolism | Brain - drug effects | Blood-Brain Barrier - pathology | Animals | Central Nervous System Agents - administration & dosage | Alzheimer Disease - metabolism | Brain - pathology | Central Nervous System Agents - metabolism | Tight Junctions - pathology | Drugs | Medical colleges | Drug delivery systems | Chronic diseases | Brain damage | Vehicles | Nervous system | Blood-brain barrier | Alzheimers disease | Pharmaceutical sciences
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Journal Article
Journal Article
Brain Behavior and Immunity, ISSN 0889-1591, 11/2018, Volume 74, pp. 3 - 6
Journal Article