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NATURE COMMUNICATIONS, ISSN 2041-1723, 10/2019, Volume 10, Issue 1, pp. 1 - 11
5-Fluorouracil (5-FU) is a chemotherapeutic drug commonly used for the treatment of solid cancers. It is proposed that 5-FU interferes with nucleotide... 
BASE EXCISION-REPAIR | SIGNATURES | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | ADULT STEM-CELLS | THYMIDYLATE-SYNTHETASE | OXALIPLATIN | MECHANISMS | ACCUMULATION | URACIL | DNA biosynthesis | Organoids | 5-Fluorouracil | Intestine | Breast cancer | Genomes | Nucleotides | Mutation | Deoxyribonucleic acid--DNA | Tumors | Esophagus | Gene sequencing
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16666 - 16671
Hutchinson–Gilford progeria syndrome (HGPS) is an extremely rare, fatal, segmental premature aging syndrome caused by a mutation in LMNA that produces the... 
Pediatrics | Progeria | Sensorineural hearing loss | Bones | Children | Lamins | Weight gain | Child health services | Vascular stiffness | Audiology | Cardiovascular disease | SCH66336 | Laminopathy | Translational medicine | cardiovascular disease | translational medicine | PULSE-WAVE VELOCITY | MULTIDISCIPLINARY SCIENCES | PHENOTYPE | REFERENCE VALUES | LAMIN | FARNESYL TRANSFERASE INHIBITORS | HEALTHY-CHILDREN | MOUSE MODEL | DISEASE | BONE | PROGRESSION | laminopathy | Carotid Arteries - drug effects | Pulse Wave Analysis | Humans | Child, Preschool | Pyridines - pharmacokinetics | Male | Fatigue - chemically induced | Diarrhea - chemically induced | Progeria - drug therapy | Dose-Response Relationship, Drug | Farnesyltranstransferase - metabolism | Pyridines - adverse effects | Enzyme Inhibitors - pharmacokinetics | Progeria - physiopathology | Progeria - pathology | Female | Piperidines - pharmacokinetics | Weight Gain - drug effects | Farnesyltranstransferase - antagonists & inhibitors | Child | Pyridines - therapeutic use | Enzyme Inhibitors - adverse effects | Drug Administration Schedule | Treatment Outcome | Enzyme Inhibitors - therapeutic use | Vomiting - chemically induced | Piperidines - therapeutic use | Piperidines - adverse effects | Adolescent | Carotid Arteries - pathology | Transferases | Clinical trials | Physiological aspects | Development and progression | Health aspects | Methods | Biological Sciences
Journal Article
by Cain, Lauren E and Logan, Roger and Robins, James M and Sterne, Jonathan A. C and Sabin, Caroline and Bansi, Loveleen and Justice, Amy and Goulet, Joseph and van Sighem, Ard and de Wolf, Frank and Bucher, Heiner C and von Wyl, Viktor and Esteve, Anna and Casabona, Jordi and del Amo, Julia and Moreno, Santiago and Seng, Remonie and Meyer, Laurence and Perez-Hoyos, Santiago and Muga, Roberto and Lodi, Sara and Lanoy, Emilie and Costagliola, Dominique and Hernan, Miguel A and Ainsworth, J and Anderson, J and Babiker, A and Delpech, V and Dunn, D and Easterbrook, P and Fisher, M and Gazzard, B and Gilson, R and Gompels, M and Hill, T and Johnson, M and Leen, C and Orkin, C and Phillips, A and Pillay, D and Porter, K and Sabin, C and Schwenk, A and Walsh, J and Bansi, L and Glabay, A and Thomas, R and Jones, K and Perry, N and Pullin, A and Churchill, D and Nelson, M and Asboe, D and Bulbeck, S and Mandalia, S and Clarke, J and Munshi, S and Post, F and Khan, Y and Patel, P and Karim, F and Duffell, S and Man, S. L and Williams, I and Dooley, D and Youle, M and Lampe, F and Smith, C and Grabowska, H and Chaloner, C and Ismajani Puradiredja, D and Weber, J and Kemble, C and Mackie, N and Winston, A and Wilson, A and Bezemer, D. O and Gras, L. A. J and Kesselring, A. M and van Sighem, A. I and Smit, C and Zhang, S and Zaheri, S and Prins, J. M and Boer, K and Bos, J. C and Geerlings, S. E and Godfried, M. H and Haverkort, M. E and Kuijpers, T. W and Lange, J. M. A and van der Meer, J. T. M and Nellen, F. J. B and Pajkrt, D and van der Poll, T and Reiss, P and Scherpbier, H. J and van der Valk, M and Vrouenraets, S. M. E and van Vugt, M and ... and HIV-CAUSAL Collaboration
Annals of internal medicine, ISSN 0003-4819, 2011, Volume 154, Issue 8, pp. 509 - 515
Journal Article
JAMA Neurology, ISSN 2168-6149, 04/2015, Volume 72, Issue 4, pp. 396 - 404
Journal Article
Circulation, ISSN 0009-7322, 07/2016, Volume 134, Issue 2, pp. 114 - 125
Journal Article
Journal of Neurology, ISSN 0340-5354, 10/2019, Volume 266, Issue 10, pp. 2481 - 2487
To characterize the clinical symptoms and magnetic resonance imaging (MRI) findings of unilateral cortical FLAIR-hyperintense Lesions in Anti-MOG-associated... 
Neurology | Encephalitis | Neurosciences | Medicine & Public Health | MOG | Myelin oligodendrocyte glycoprotein | MRI | Autoimmune | Neuroradiology | Seizures | Literature reviews | Neuroimaging | Headache | Oligodendrocyte-myelin glycoprotein | Nuclear magnetic resonance--NMR | Magnetic resonance imaging | Cortex | Headaches | Fever
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2016
Abstract Matrix metalloproteinase-9 (MMP-9) is robustly elevated in the first week post-myocardial infarction (MI). Targeted deletion of the MMP-9 gene... 
Cardiovascular
Journal Article
by Lorenzi, Gayle M and Braffett, Barbara H and Arends, Valerie L and Danis, Ronald P and Diminick, Lisa and Klumpp, Kandace A and Morrison, Anthony D and Soliman, Elsayed Z and Steffes, Michael W and Cleary, Patricia A and Crandall, J and Reid, M and Brown-Friday, J and Engel, S and Sheindlin, J and Phillips, M and Martinez, H and Shamoon, H and Engel, H and Gubitosi-Klug, R and Mayer, L and Pendegast, S and Zegarra, H and Miller, D and Singerman, L and Smith-Brewer, S and Novak, M and Quin, J and Genuth, Saul and Palmert, M and Brown, E and McConnell, J and Pugsley, P and Crawford, P and Dahms, W and Brillon, D and Lackaye, M.E and Kiss, S and Chan, R and Orlin, A and Rubin, M and Reppucci, V and Lee, T and Heinemann, M and Chang, S and Levy, B and Jovanovic, L and Richardson, M and Bosco, B and Dwoskin, A and Hanna, R and Barron, S and Campbell, R and Whitehouse, F and Kruger, D and Jones, J.K and Edwards, P.A and Bhan, A and Carey, J.D and Angus, E and Thomas, A and McLellan, M and Galprin, A and Bergenstal, R and Johnson, M and Gunyou, K and Thomas, L and Laechelt, J and Hollander, P and Spencer, M and Kendall, D and Cuddihy, R and Callahan, P and List, S and Gott, J and Rude, N and Olson, B and Franz, M and Castle, G and Birk, R and Nelson, J and Freking, D and Gill, L and Mestrezat, W and Etzwiler, D and Morgan, K and Aiello, L.P and Golden, E and Arrigg, P and Asuquo, V and Beaser, R and Bestourous, L and Cavallerano, J and Cavicchi, R and Ganda, O and Hamdy, O and Kirby, R and Murtha, T and Schlossman, D and Shah, S and ... and DCCT-EDIC Res Grp and DCCT/EDIC Research Group and the DCCT/EDIC Research Group
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0141286
Journal Article