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International Journal of Pharmaceutics, ISSN 0378-5173, 11/2019, Volume 571, p. 118696
In the small intestine, P-glycoprotein (P-gp) may limit the permeability of its substrates, which lead to reduced oral absorption. To circumvent the effect of... 
P-glycoprotein | Montmorillonite | Nanocomposites | Digoxin | Intestinal absorption | Polysorbate 20
Journal Article
Genomics, ISSN 0888-7543, 12/2019, Volume 111, Issue 6, pp. 1557 - 1565
Hyperosmolality is found under physiological conditions in the kidneys, whereas hyperosmolality in other tissues may be associated with pathological... 
Hyperosmolality | Pathway analysis | MDCK cells | RNA-seq | Membrane transporters | NaCl | Raffinose
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 07/2019, Volume 566, p. 410
Recently, it has become evident that pharmaceutical excipients may interfere with the activity of ATP-binding cassette (ABC) transporters and solute carriers... 
Drug resistance in microorganisms | Surface active agents | Pharmacy | Drugstores | Product development
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 06/2019, Volume 565, pp. 306 - 315
The aim of the present study was to investigate the ability of non-ionic surfactants to inhibit MRP2-mediated transport in MDCKII MRP2 cells. Transport studies... 
Etoposide | MRP2 | Digoxin | Non-ionic surfactants | Efflux transporters | MDCKII MRP2 cells | Surface active agents | Glycine | Analysis
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 05/2018, Volume 543, Issue 1-2, pp. 352 - 360
The aim of the present work was to investigate the ability of nonionic surfactants to increase the oral absorption of the P-glycoprotein substrate etoposide... 
mdr1a deficient (KO) | Etoposide | Sprague-Dawley rats | MDCKII MDR1 | Caco-2 | Polysorbate 20 | DELIVERY-SYSTEMS | DRUG-RESISTANCE | CRITICAL MICELLE CONCENTRATION | NONIONIC SURFACTANTS | P-GLYCOPROTEIN | LUNG-CANCER | IN-VITRO | PHARMACOLOGY & PHARMACY | ABC TRANSPORTERS | ABSORPTION | MULTIDRUG-RESISTANCE | Drugstores | Permeability | Surface active agents | Pharmacy
Journal Article
American Journal of Physiology, ISSN 0193-1849, 01/2014, Volume 306, Issue 1, p. E65
  The proton-coupled amino acid transporter 1 (PAT1) is a transporter of amino acids in small intestinal enterocytes. PAT1 is, however, also capable of... 
Cell growth | Rodents | Cell division | Amino acids | Smooth muscle
Journal Article
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 07/2013, Volume 65, Issue 7, pp. 970 - 979
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 06/2012, Volume 81, Issue 2, p. 458
In human intestinal epithelial Caco-2 cells, basolateral GABA uptake is dependent on sodium and chlorid dependent carriers. 
GABA | Monomolecular films
Journal Article
ISSN 2040-2503, 10/2016, Volume 7, Issue 1, pp. 1916 - 1924
In the present study, we have investigated ibuprofen transport in renal cell cultures with the aim of characterizing a recently proposed ibuprofen transporter.... 
Journal Article
MedChemComm, ISSN 2040-2503, 2016, Volume 7, Issue 10, pp. 1916 - 1924
In the present study, we have investigated ibuprofen transport in renal cell cultures with the aim of characterizing a recently proposed ibuprofen transporter.... 
AMINO-ACID TRANSPORTER | LOCALIZATION | CHEMISTRY, MEDICINAL | LLC-PK1 | METABOLISM | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CACO-2 | GROWTH | H+/PEPTIDE COTRANSPORTER PEPT1 | TAURINE TRANSPORTER | EXPRESSION
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2010, Volume 161, Issue 8, pp. 1793 - 1805
Journal Article
ACS medicinal chemistry letters, ISSN 1948-5875, 04/2014, Volume 5, Issue 4, p. 352
In this study the μ opioid receptor (MOR) ligands DALDA (Tyr-d-Arg-Phe-Lys-NH ) and Dmt -DALDA (Dmt-d-Arg-Phe-Lys-NH , Dmt = 2',6'-dimethyltyrosine) were... 
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2004, Volume 311, Issue 3, pp. 1088 - 1096
Journal Article