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1. Full Text Abstract LB-135: Selective small molecule inhibition of the N-terminal BET bromodomain
by Seitzberg, Jimmi G and Hansen, Margit H and Kronborg, Tine T. Akinleminu and Underwood, Christina R and Friberg, Gitte and Tonnesen, Berit and Teuber, Lene and Franch, Thomas and Nielsen, Søren J
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. LB-135 - LB-135
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2. Full Text Abstract LB-476: A universal method for elimination of haemolyzed plasma samples that improves miRNA signature performance for early detection of colorectal cancer
by Nielsen, Søren J and Blondal, Thorarinn and Teilum, Maria W and Andersen, Claus L and Orntoft, Torben and Brünner, Nils and Stenvang, Jan and Nielsen, Hans J and Baker, Adam and Mouritzen, Peter
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. LB-476 - LB-476
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3. Full Text Abstract LB-68: Comparative analysis of the miRNome in tumors and plasma from colorectal cancer patients
by Nielsen, Søren J and Jacobsen, Nana and Fog, Jacob U and Willenbrock, Hanni and Baker, Adam and Ørntoft, Torben F and Nielsen, Hans J and Andersen, Claus L and Møller, Søren
Cancer Research, ISSN 0008-5472, 04/2010, Volume 70, Issue 8 Supplement, pp. LB-68 - LB-68
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4. Full Text Abstract 2816: Discovery of a miRNA-based RT-qPCR signature able to detect early stage colorectal cancer in blood plasma
by Nielsen, Søren J and Willenbrock, Hanni and Fog, Jacob U and Jacobsen, Nana and Stenvang, Jan and Blondal, Thorarinn and Ørntoft, Torben and Brünner, Nils and Andersen, Claus L and Nielsen, Hans J and Baker, Adam
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 2816 - 2816
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5. Full Text In situ metabolomic- and transcriptomic-profiling of the host-associated cyanobacteria Prochloron and Acaryochloris marina
by Behrendt, Lars and Raina, Jean-Baptiste and Lutz, Adrian and Kot, Witold and Albertsen, Mads and Halkjær-Nielsen, Per and Sørensen, Søren J and Larkum, Anthony Wd and Kühl, Michael
ISME Journal, ISSN 1751-7362, 02/2018, Volume 12, Issue 2, pp. 556 - 567
The tropical ascidian Lissoclinum patella hosts two enigmatic cyanobacteria: (1) the photoendo-symbiont Prochloron spp., a producer of valuable bioactive... 
CARBON FIXATION | CHLOROPHYLL-D | DIDEMNID ASCIDIANS | N-2 FIXATION | ESCHERICHIA-COLI | FTSH PROTEASE | STRAIN PCC 7942 | GENE-EXPRESSION | ECOLOGY | MICROBIOLOGY | LISSOCLINUM-PATELLA | COLONIAL ASCIDIANS | Metabolomics | Chlorophyll | Transcription | Peptides | Cultivation | Carbon dioxide | Ribulose-bisphosphate carboxylase | Amino acids | I.R. radiation | Genomes | Infrared signatures | Gene expression | Gene sequencing | Quenching | Consortia | Photorespiration | Bioactive compounds | Photosynthates | Cyanobacteria | Photosynthesis | Original
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6. Investigation of the bacteriophage community in induced lysates of undefined mesophilic mixed-strain DL-cultures using classical and metagenomic approaches
by Musemma K Muhammed and Mette L Olsen and Witold Kot and Horst Neve and Josué L Castro-Mejía and Thomas Janzen and Lars H Hansen and Dennis S Nielsen and Søren J Sørensen and Knut J Heller and Finn K Vogensen
International Journal of Food Microbiology, ISSN 0168-1605, 05/2018, Volume 272, p. 61
To investigate the notion that starter cultures can be a reservoir of bacteriophages (phages) in the dairy environment, strains of three DL-starters (undefined... 
Bacteriophages | Lactococcus lactis | Mitomycin | Microbiology | Communities | Phages | Cultures | Cheese | Leuconostoc | Starter cultures | Lysates | Starters | Bacteria | Mitomycin C | Species
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7. Metagenomic Analysis of Dairy Bacteriophages: Extraction Method and Pilot Study on Whey Samples Derived from Using Undefined and Defined Mesophilic Starter Cultures
by Musemma K Muhammed and Witold Kot and Horst Neve and Jennifer Mahony and Josu L Castro-Mejía and Lukasz Krych and Lars H Hansen and Dennis S Nielsen and Søren J Sørensen and Knut J Heller and Douwe van Sinderen and Finn K Vogensen
Applied and Environmental Microbiology, ISSN 0099-2240, 10/2017, Volume 83, Issue 19
Despite being potentially highly useful for characterizing the biodiversity of phages, metagenomic studies are currently not available for dairy... 
Bacteriophages | Lactococcus lactis | Dairy products | Genomics | Phages | Cultures | Leuconostoc | Whey | Electron microscopy | Biodiversity | Proteins | Starter cultures | Transmission electron microscopy | Next-generation sequencing | Relative abundance | Bacteria | Dairies | Prophages | Milk
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8. Full Text Comment on “Re-examining premature mortality in anorexia nervosa: A meta-analysis redux” by Keshaviah et al. [Comprehensive Psychiatry 55 (2014) 1773–1784]
by Nielsen, Søren and Mitchell, Alex J
Comprehensive Psychiatry, ISSN 0010-440X, 2015, Volume 61, pp. 131 - 132
Psychiatry
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9. Full Text Relative Atrial Natriuretic Peptide Deficiency and Inadequate Renin and Angiotensin II Suppression in Obese Hypertensive Men
by Asferg, Camilla L and Nielsen, Søren J and Andersen, Ulrik B and Linneberg, Allan and Møller, Daniel V and Hedley, Paula L and Christiansen, Michael and Goetze, Jens P and Esler, Murray and Jeppesen, Jørgen L
Hypertension, ISSN 0194-911X, 07/2013, Volume 62, Issue 1, pp. 147 - 153
Obesity is a strong risk factor for hypertension, but the mechanisms by which obesity leads to hypertension are incompletely understood. On this background, we... 
angiotensin | natriuretic peptides | hypertension | aldosterone | renin | sympathetic nervous system | COMMON VARIANTS | METABOLIC SYNDROME | SODIUM | HUMANS | ALDOSTERONE SYSTEM | DIABETES-MELLITUS | CARDIOVASCULAR-DISEASE RISK | SYMPATHETIC ACTIVATION | PHYSIOLOGICAL-ROLE | PERIPHERAL VASCULAR DISEASE | AMBULATORY BLOOD-PRESSURE | Body Composition | Prognosis | Follow-Up Studies | Obesity - complications | Humans | Middle Aged | Angiotensin II - blood | Male | Obesity - physiopathology | Renin-Angiotensin System - physiology | Renin - blood | Atrial Natriuretic Factor - blood | Obesity - blood | Atrial Natriuretic Factor - deficiency | Hypertension - physiopathology | Hypertension - blood | Hypertension - complications | Adult | Aged | Blood Pressure - physiology | Blood Pressure Monitoring, Ambulatory
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10. Full Text Serum proatrial natriuretic peptide concentrations during oral glucose-induced acute hyperinsulinemia in lean and obese men
by Asferg, Camilla L and Nielsen, Søren J and Andersen, Ulrik B and Linneberg, Allan and Goetze, Jens P and Jeppesen, Jørgen L
Peptides, ISSN 0196-9781, 01/2019, Volume 111, pp. 98 - 102
Atrial natriuretic peptide (ANP) is primarily seen as a hormone involved in salt and water homeostasis and blood pressure regulation. Evidence supports a link... 
Insulin resistance | Atrial natriuretic peptide | Proatrial natriuretic peptide | Glucose challenge | Insulin | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | PLASMA ATRIAL | PHARMACOLOGY & PHARMACY | BLOOD-PRESSURE | Glucose - adverse effects | Humans | Middle Aged | Insulin Resistance | Male | Insulin - blood | Atrial Natriuretic Factor - blood | Obesity - blood | Hyperinsulinism - chemically induced | Thinness - blood | Adult | Aged | Hyperinsulinism - blood
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11. Full Text Rapid TaqMan-Based Quantification of Chlorophylld-Containing Cyanobacteria in the Genus Acaryochloris
by Behrendt, Lars and Nielsen, Jeppe L and Sørensen, Søren J and Larkum, Anthony W. D and Winther, Jakob R and Kühl, Michael
Applied and Environmental Microbiology, ISSN 0099-2240, 05/2014, Volume 80, Issue 10, pp. 3244 - 3249
ABSTRACTReports of the chlorophyll (Chl)d-containing cyanobacteriumAcaryochlorishave accumulated since its initial discovery in 1996. The majority of this... 
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12. Rapid TaqMan-Based Quantification of Chlorophyll d-Containing Cyanobacteria in the Genus Acaryochloris
by Lars Behrendt and Jeppe L Nielsen and Søren J Sørensen and Anthony W D Larkum and Jakob R Winther and Michael Kühl
Applied and Environmental Microbiology, ISSN 0099-2240, 05/2014, Volume 80, Issue 10, p. 3244
  Reports of the chlorophyll (Chl) d-containing cyanobacterium Acaryochloris have accumulated since its initial discovery in 1996. The majority of this... 
Chlorophyll | Microbiology | Algae | Environmental testing | Gram-negative bacteria | Cells | Nonnative species
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13. Full Text Biofilms in chronic infections – a matter of opportunity – monospecies biofilms in multispecies infections
by Burmølle, Mette and Thomsen, Trine Rolighed and Fazli, Mustafa and Dige, Irene and Christensen, Lise and Homøe, Preben and Tvede, Michael and Nyvad, Bente and Tolker-Nielsen, Tim and Givskov, Michael and Moser, Claus and Kirketerp-Møller, Klaus and Johansen, Helle Krogh and Høiby, Niels and Jensen, Peter Østrup and Sørensen, Søren J and Bjarnsholt, Thomas
FEMS Immunology & Medical Microbiology, ISSN 0928-8244, 08/2010, Volume 59, Issue 3, pp. 324 - 336
Abstract It has become evident that aggregation or biofilm formation is an important survival mechanism for bacteria in almost any environment. In this review,... 
diagnostics | chronic infections | biofilm | NONTYPABLE HAEMOPHILUS-INFLUENZAE | POLYMORPHONUCLEAR LEUKOCYTES | IN-SITU HYBRIDIZATION | MICROBIOLOGY | CHRONIC WOUNDS | VENOUS LEG ULCERS | INITIAL DENTAL BIOFILM | OTITIS-MEDIA | BACTERIAL DIVERSITY | MIDDLE-EAR | PSEUDOMONAS-AERUGINOSA BIOFILMS | Bacterial Adhesion | Bacteria - growth & development | Bacteria - isolation & purification | Humans | Biofilms - growth & development | Bacteria - classification | Bacteria - pathogenicity | Biodiversity | Chronic Disease | Bacterial Infections - microbiology | Cystic fibrosis | Universities and colleges | Ecosystems | Health aspects | Biofilms | Aggregates | Intestine | Fillers | Fibrosis | Chronic infection | Bacteria | Otitis media | Infections | Diagnostic systems | Niches
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14. Full Text Effectiveness of a comprehensive interactive eHealth intervention on patient-reported and clinical outcomes in patients with an implantable cardioverter defibrillator [ACQUIRE-ICD trial]: Study protocol of a national Danish randomised controlled trial
by Pedersen, Susanne S and Skovbakke, Søren J and Wiil, Uffe K and Schmidt, Thomas and dePont Christensen, Rene and Brandt, Carl J and Sørensen, Jan and Vinther, Michael and Larroudé, Charlotte E and Melchior, Thomas M and Riahi, Sam and Smolderen, Kim G.E and Spertus, John A and Johansen, Jens B and Nielsen, Jens C
BMC Cardiovascular Disorders, ISSN 1471-2261, 07/2018, Volume 18, Issue 1, pp. 136 - 12
Background: In Denmark and other countries, there has been a shift in the management of patients with an implantable cardioverter defibrillator (ICD) with... 
Device acceptance | Patient-centered tools | Heart disease | EHealth intervention | Implantable cardioverter defibrillator | Depression | Anxiety | Quality of life | MORTALITY | D PERSONALITY | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | VENTRICULAR TACHYARRHYTHMIAS | SCIENTIFIC STATEMENT | ELECTRONIC DEVICES | eHealth intervention | ACCEPTANCE | QUALITY-OF-LIFE | HEALTH-STATUS | Predictive Value of Tests | Prospective Studies | Humans | Risk Factors | Heart Failure - physiopathology | Treatment Outcome | Mental Health | Electric Countershock - adverse effects | Randomized Controlled Trials as Topic | Heart Failure - therapy | Multicenter Studies as Topic | Electric Countershock - instrumentation | Time Factors | Defibrillators, Implantable | Remote Sensing Technology - instrumentation | Denmark | Quality of Life | Heart Failure - diagnosis | Health Status | Heart Failure - psychology | Telemetry - instrumentation | Telemedicine - instrumentation | Patient Reported Outcome Measures | Prevention | Usage | Care and treatment | Analysis | Cardiac arrest | E-health | Implantable cardioverter-defibrillators | Intervention | Heart failure | Mortality | Feasibility studies | Objectives | Clinical trials | Cardiovascular disease | Behavior modification | Mental depression | Management | Medical screening | Patients | Clinical outcomes | Morbidity | Empowerment | Hospitals | Nursing | Anxieties | Internet | Cost analysis
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15. Full Text Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase
by Olesen, Uffe.H and Petersen, Jakob G and Garten, Antje and Kiess, Wieland and Yoshino, Jun and Imai, Shin-Ichiro and Christensen, Mette K and Fristrup, Peter and Thougaard, Annemette V and Björkling, Fredrik and Jensen, Peter B and Nielsen, Søren J and Sehested, Maxwell
BMC Cancer, ISSN 1471-2407, 12/2010, Volume 10, Issue 1, pp. 677 - 677
Background: Inhibitors of nicotinamide phosphoribosyltransferase (NAMPT) are promising cancer drugs currently in clinical trials in oncology, including APO866,... 
POTENT ANTITUMOR-ACTIVITY | NAD | IN-VITRO | ONCOLOGY | CRYSTAL-STRUCTURE | ADENINE-DINUCLEOTIDE BIOSYNTHESIS | CHS-828 | PHASE-I | CANCER | NAMPT/PBEF/VISFATIN | FK866 | Humans | Nicotinamide Phosphoribosyltransferase - chemistry | Drug Resistance, Neoplasm | Guanidines - pharmacology | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Antineoplastic Agents - metabolism | Cytokines - chemistry | Dose-Response Relationship, Drug | Transfection | Neoplasms - genetics | Nicotinamide Phosphoribosyltransferase - metabolism | Piperidines - pharmacology | Time Factors | Inhibitory Concentration 50 | Acrylamides - metabolism | Female | Antineoplastic Agents - pharmacology | Acrylamides - pharmacology | Binding Sites | Cytokines - genetics | Guanidines - metabolism | Binding, Competitive | Catalytic Domain | Cytokines - metabolism | Enzyme Inhibitors - metabolism | Piperidines - metabolism | HCT116 Cells | Enzyme Inhibitors - pharmacology | Cyanides - pharmacology | Models, Molecular | Neoplasms - enzymology | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Cyanides - metabolism | Nicotinamide Phosphoribosyltransferase - genetics | Animals | Mice, Nude | Cell Line, Tumor | Protein Conformation | Mice | Cytokines - antagonists & inhibitors | Mutation | Neoplasms - pathology | Niacinamide | Genetic aspects | Research | Gene mutations | Drug resistance
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16. Full Text Gut microbiota in human adults with type 2 diabetes differs from non-diabetic adults
by Larsen, Nadja and Vogensen, Finn K and Van Den Berg, Frans W. J and Nielsen, Dennis Sandris and Andreasen, Anne Sofie and Pedersen, Bente K and Al-Soud, Waleed Abu and Sørensen, Søren J and Hansen, Lars H and Jakobsen, Mogens
PLoS ONE, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, p. e9085
Background: Recent evidence suggests that there is a link between metabolic diseases and bacterial populations in the gut. The aim of this study was to assess... 
REAL-TIME PCR | OBESITY | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | LACTIC-ACID BACTERIA | FECAL MICROBIOTA | WEIGHT-LOSS | ANTIBIOTIC-TREATMENT | RIBOSOMAL-RNA | HUMAN FECES | LACTOBACILLUS | Body Mass Index | Humans | Middle Aged | Male | DNA, Bacterial - chemistry | Colony Count, Microbial | Bacteria - genetics | Sequence Analysis, DNA | Feces - microbiology | Bacteria - isolation & purification | DNA, Bacterial - genetics | Diabetes Mellitus, Type 2 - physiopathology | Intestines - microbiology | Bacteria - classification | RNA, Ribosomal, 16S - genetics | Adult | Aged | Type 2 diabetes | Diabetics | Body mass index | Medical research | Microbiota (Symbiotic organisms) | RNA | Medicine, Experimental | Glucose | Dextrose | rRNA 16S | Breastfeeding & lactation | Control methods | Genes | Biology | Food science | Subgroups | Microbiota | E coli | Intestine | Bacteria | Intestinal microflora | Feces | Diabetes mellitus (non-insulin dependent) | Digestive tract | Obesity | Digestive system | Diabetes mellitus | Diseases | Studies | Glucose tolerance | Weight control | Infectious diseases | Antibiotics | Insulin resistance | Adults | Diabetes | Metabolic disorders
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17. Full Text Investigation of the bacteriophage community in induced lysates of undefined mesophilic mixed-strain DL-cultures using classical and metagenomic approaches
by Muhammed, Musemma K and Olsen, Mette L and Kot, Witold and Neve, Horst and Castro-Mejía, Josué L and Janzen, Thomas and Hansen, Lars H and Nielsen, Dennis S and Sørensen, Søren J and Heller, Knut J and Vogensen, Finn K
International Journal of Food Microbiology, ISSN 0168-1605, 05/2018, Volume 272, pp. 61 - 72
To investigate the notion that starter cultures can be a reservoir of bacteriophages (phages) in the dairy environment, strains of three DL-starters (undefined... 
Mesophilic | Induction | Spontaneous | Abundance | DL-starter | Bacterio(phages) | Mitomycin C | Metagenome | Morphotypes | VIRULENT PHAGE | PLAQUE-ASSAY | FOOD SCIENCE & TECHNOLOGY | LACTOCOCCUS-LACTIS BACTERIOPHAGES | CLASSIFICATION | MICROBIOLOGY | GENETIC-CHARACTERIZATION | IDENTIFICATION | Metagenonte | TEMPERATE BACTERIOPHAGES | COMPLETE GENOME SEQUENCE | DNA | RESISTANCE
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