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Drug Metabolism and Disposition, ISSN 0090-9556, 04/2019, Volume 47, Issue 4, pp. 377 - 385
A recent in vitro study suggested that CYP2C8 is essential in the metabolism of desloratadine, an H1 receptor antagonist. If the proposed biotransformation... 
UGT2B10 GENOTYPE | CYP2C8 | PHARMACOKINETICS | METABOLISM | PLASMA-CONCENTRATIONS | MARKEDLY INCREASES | DEPENDENT INHIBITOR | GLUCURONIDATION | PHARMACOLOGY & PHARMACY | TRANSPORTING POLYPEPTIDE 1B1 | DRUG-DRUG INTERACTION | Time dependence | Metabolites | Biotransformation | Gemfibrozil | Drug interactions | Clopidogrel | Drug interaction | Metabolism | Substrates
Journal Article
Journal Article
Drug Metabolism and Disposition, ISSN 0090-9556, 02/2018, Volume 46, Issue 2, p. 141
The antiplatelet drug clopidogrel is metabolized to an acyl-β-d-glucuronide, which causes time-dependent inactivation of CYP2C8. Our aim was to characterize... 
Enzymes | Imatinib | Deactivation | UDP-glucuronosyltransferase | Incubation | Liver | Pharmacology | Carboxylic acids | Inactivation | Microsomes | Inhibitors | Acids | Clonal deletion | Mefenamic acid | Intestine | Human performance | Deletion | Clopidogrel | NADP | Inhibition | Pharmacokinetics | Recombinant | Glucuronosyltransferase
Journal Article
Journal of Accounting Research, ISSN 0021-8456, 5/2013, Volume 51, Issue 2, pp. 349 - 387
This study investigates the implicit financial incentives of individual Big 4 audit partners by examining the association between a partner's compensation and... 
ORGANIZATION | FIRM VALUE | REPUTATIONS | BUSINESS, FINANCE | QUALITY | MORAL HAZARD | INCENTIVE COMPENSATION | AGENCY THEORY | OFFICE SIZE | SPECIALIZATION | FEES | Business schools | Partnership | Economic incentives | Analysis | Studies | Audits | Executive compensation | Big Four accounting firms
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2012, Volume 109, Issue 16, pp. 6024 - 6029
Journal Article
Journal of Veterinary Internal Medicine, ISSN 0891-6640, 11/2018, Volume 32, Issue 6, pp. 2074 - 2081
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 02/2019, Volume 105, Issue 2, pp. 448 - 457
CYP3A enzymes participate in the elimination of ticagrelor and the bioactivation of clopidogrel and prasugrel. We studied the effects of functional CYP3A... 
GENETIC POLYMORPHISMS | PHARMACOKINETICS | DETERMINANTS | GRAPEFRUIT JUICE | PHARMACOLOGY & PHARMACY | SINGLE NUCLEOTIDE POLYMORPHISM | PHARMACODYNAMICS | INHIBITORS | OUTCOMES | CYP3A4 | CYP2C19
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 07/2015, Volume 80, Issue 1, pp. 139 - 145
Journal Article