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1. Full Text Mortality risk in preterm and small-for-gestational-age infants in low-income and middle-income countries: a pooled country analysis
by Katz, Joanne, Prof and Lee, Anne CC, MD and Kozuki, Naoko, MSPH and Lawn, Joy E, Prof and Cousens, Simon, Prof and Blencowe, Hannah, MRCPCH and Ezzati, Majid, Prof and Bhutta, Zulfiqar A, Prof and Marchant, Tanya, PhD and Willey, Barbara A, PhD and Adair, Linda, Prof and Barros, Fernando, Prof and Baqui, Abdullah H, Prof and Christian, Parul, Prof and Fawzi, Wafaie, Prof and Gonzalez, Rogelio, Prof and Humphrey, Jean, Prof and Huybregts, Lieven, PhD and Kolsteren, Patrick, Prof and Mongkolchati, Aroonsri, PhD and Mullany, Luke C, PhD and Ndyomugyenyi, Richard, PhD and Nien, Jyh Kae, MD and Osrin, David, PhD and Roberfroid, Dominique, PhD and Sania, Ayesha, PhD and Schmiegelow, Christentze, PhD and Silveira, Mariangela F, PhD and Tielsch, James, Prof and Vaidya, Anjana, PhD and Velaphi, Sithembiso C, Mmed and Victora, Cesar G, Prof and Watson-Jones, Deborah, PhD and Black, Robert E, Prof and CHERG Small-for-Gestational-Age-Pr and CHERG Small-for-Gestational-Age-Preterm Birth Working Group
Lancet, The, ISSN 0140-6736, 2013, Volume 382, Issue 9890, pp. 417 - 425
Summary Background Babies with low birthweight (<2500 g) are at increased risk of early mortality. However, low birthweight includes babies born preterm and... 
Internal Medicine | COHORT PROFILE | MEDICINE, GENERAL & INTERNAL | INTRAUTERINE GROWTH-RETARDATION | LOW-BIRTH-WEIGHT | NEONATAL-MORTALITY | MULTIPLE MICRONUTRIENT SUPPLEMENTATION | FETAL-GROWTH | DOUBLE-BLIND | RANDOMIZED-TRIAL | PLACEBO-CONTROLLED TRIAL | VITAMIN-A | Income - statistics & numerical data | Asia - epidemiology | South America - epidemiology | Prevalence | Infant Mortality | Humans | Infant, Premature | Risk Factors | Infant | Infant, Small for Gestational Age | Africa South of the Sahara - epidemiology | Infant, Newborn | Causes of | Infants | Prognosis | Birth weight, Low | Demographic aspects | Patient outcomes | United Kingdom | Chile | Health aspects | Mortality | Babies | Low income groups | Ultrasonic imaging | Menstruation | Newborn babies | Review boards | Population | Births | Infant mortality | Birth weight | Age | Recruitment
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2. Full Text National and regional estimates of term and preterm babies born small for gestational age in 138 low-income and middle-income countries in 2010
by Lee, Anne CC, Dr and Katz, Joanne, ScD and Blencowe, Hannah, MRCPCH and Cousens, Simon, DipMathStat and Kozuki, Naoko, MSPH and Vogel, Joshua P, MBBS and Adair, Linda, PhD and Baqui, Abdullah H, DrPH and Bhutta, Zulfiqar A, PhD and Caulfield, Laura E, PhD and Christian, Parul, DrPH and Clarke, Siân E, PhD and Ezzati, Majid, PhD and Fawzi, Wafaie, DrPH and Gonzalez, Rogelio, PhD and Huybregts, Lieven, PhD and Kariuki, Simon, PhD and Kolsteren, Patrick, PhD and Lusingu, John, PhD and Marchant, Tanya, PhD and Merialdi, Mario, MD and Mongkolchati, Aroonsri, PhD and Mullany, Luke C, PhD and Ndirangu, James, MSc and Newell, Marie-Louise, PhD and Nien, Jyh Kae, MD and Osrin, David, PhD and Roberfroid, Dominique, PhD and Rosen, Heather E, MPP and Sania, Ayesha, PhD and Silveira, Mariangela F, PhD and Tielsch, James, PhD and Vaidya, Anjana, PhD and Willey, Barbara A, PhD and Lawn, Joy E, PhD and Black, Robert E, MD and CHERG SGA-Preterm Birth and CHERG SGA-Preterm Birth Working Group
Lancet Global Health, ISSN 2214-109X, 2013, Volume 1, Issue 1, pp. e26 - e36
Summary Background National estimates for the numbers of babies born small for gestational age and the comorbidity with preterm birth are unavailable. We aimed... 
Internal Medicine | SYSTEMATIC ANALYSIS | INTRAUTERINE GROWTH-RETARDATION | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | NEONATAL-MORTALITY | MULTIPLE MICRONUTRIENT SUPPLEMENTATION | FETAL-GROWTH | INFANT-MORTALITY | DOUBLE-BLIND | RANDOMIZED CONTROLLED-TRIAL | TIME TRENDS | BRAZIL BIRTH COHORT | Prevalence | Global Health | Developing Countries - statistics & numerical data | Humans | Infant, Premature | Female | Infant, Small for Gestational Age | Male | Premature Birth - epidemiology | Infant, Newborn
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3. Full Text Identification of patients at risk for early onset and/or severe preeclampsia with the use of uterine artery Doppler velocimetry and placental growth factor
by Espinoza, Jimmy, MD and Romero, Roberto, MD and Nien, Jyh Kae, MD and Gomez, Ricardo, MD and Kusanovic, Juan Pedro, MD and Gonçalves, Luis F., MD and Medina, Luis, MD and Edwin, Sam, PhD and Hassan, Sonia, MD and Carstens, Mario, MD and Gonzalez, Rogelio, MD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2007, Volume 196, Issue 4, pp. 326.e1 - 326.e13
Objective Preeclampsia has been proposed to be an antiangiogenic state that may be detected by the determination of the concentrations of the soluble vascular... 
Obstetrics and Gynecology | gestational hypertension | soluble vascular endothelial growth factor receptor-1 (VEGFR-1) | uterine artery Doppler velocimetry | small for gestational age | placental growth factor (PlGF) | vascular endothelial growth factor (VEGF) | preeclampsia | 2ND TRIMESTER | VASCULAR DEVELOPMENT | FETAL-GROWTH | VELOCITY WAVE-FORMS | EXPECTANT MANAGEMENT | SPIRAL ARTERIES | OBSTETRICS & GYNECOLOGY | CIRCULATING ANGIOGENIC FACTORS | PHYSIOLOGICAL TRANSFORMATION | GESTATIONAL-AGE | placental growth factor (PIGF) | TROPHOBLAST DEPORTATION | Predictive Value of Tests | Pregnancy Trimester, Second | Prospective Studies | Humans | Pregnancy Proteins - metabolism | Pre-Eclampsia - mortality | Time Factors | Sensitivity and Specificity | Adult | Female | Uterus - blood supply | Pre-Eclampsia - diagnosis | Severity of Illness Index | Ultrasonography, Doppler | Biomarkers - analysis | Probability | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Chi-Square Distribution | Placenta - metabolism | Pregnancy | Ultrasonography, Prenatal | Vascular Endothelial Growth Factor Receptor-1 - analysis | Survival Analysis | Placenta Growth Factor | Uterus - diagnostic imaging | Pregnancy Outcome | Cohort Studies | Pregnancy Proteins - analysis | Development and progression | Vascular endothelial growth factor | Preeclampsia | soluble vascular endothelial growth factor receptor-1 (sVEGFR-1) | preeclampsia small for gestational age
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4. Full Text First-trimester maternal serum PP13 in the risk assessment for preeclampsia
by Romero, Roberto, MD and Kusanovic, Juan Pedro, MD and Than, Nandor Gabor, MD, PhD and Erez, Offer, MD and Gotsch, Francesca, MD and Espinoza, Jimmy, MD and Edwin, Samuel, PhD and Chefetz, Ilana, MSc and Gomez, Ricardo, MD and Nien, Jyh Kae, MD and Sammar, Marei, PhD and Pineles, Beth, BS and Hassan, Sonia S., MD and Meiri, Hamutal, PhD and Tal, Yossi, PhD and Kuhnreich, Ido, MSc and Papp, Zoltan, MD, DSci and Cuckle, Howard S., PhD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2008, Volume 199, Issue 2, pp. 122.e1 - 122.e11
Objective The objective of the study was to determine whether first-trimester maternal serum placental protein 13 (PP13) concentrations can be used in the risk... 
Obstetrics and Gynecology | risk assessment | screening | maternal serum biochemistry | high-risk pregnancy | prenatal care | BED SPIRAL ARTERIES | SOLUBLE ENDOGLIN | ELEVATED LIVER-ENZYMES | OBSTETRICS & GYNECOLOGY | UTERINE ARTERY DOPPLER | CIRCULATING ANGIOGENIC FACTORS | EARLY-ONSET PREECLAMPSIA | GESTATIONAL-AGE | LOW PLATELET COUNT | PLACENTAL ABRUPTION | ENDOTHELIAL GROWTH-FACTOR | Pre-Eclampsia - epidemiology | Predictive Value of Tests | Pregnancy Trimester, First - blood | Oligopeptides - blood | Area Under Curve | Humans | Biomarkers - blood | Case-Control Studies | Pregnancy | Pregnancy, High-Risk - blood | Pre-Eclampsia - blood | Adult | Female | ROC Curve | Pregnancy Outcome | Preeclampsia | Risk assessment
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5. Full Text Twin-to-twin transfusion syndrome: an antiangiogenic state?
by Kusanovic, Juan Pedro, MD and Romero, Roberto, MD and Espinoza, Jimmy, MD and Nien, Jyh Kae, MD and Kim, Chong Jai, MD and Mittal, Pooja, MD and Edwin, Sam, PhD and Erez, Offer, MD and Gotsch, Francesca, MD and Mazaki-Tovi, Shali, MD and Than, Nandor G., MD, PhD and Soto, Eleazar, MD and Camacho, Natalia, MD and Gomez, Ricardo, MD and Quintero, Ruben, MD and Hassan, Sonia S., MD
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2008, Volume 198, Issue 4, pp. 382.e1 - 382.e8
Objective An imbalanced chronic blood flow between the donor and recipient twin through placental vascular anastomoses is the accepted pathophysiology of... 
Obstetrics and Gynecology | placental growth factor | sFlt1 | monochorionic | sVEGFR-1 | angiogenesis | birthweight discordancy | twin pregnancy | TTTS | angiogenic factors | endoglin | PlGF | MONOCHORIONIC TWINS | VELAMENTOUS CORD INSERTION | HUMAN FETOPLACENTAL VASCULOGENESIS | sFIt1 | FETOCIDE REVERSES PREECLAMPSIA | BIRTH-WEIGHT DISCORDANCY | FACTOR RECEPTOR-1 | OBSTETRICS & GYNECOLOGY | CIRCULATING ANGIOGENIC FACTORS | TYROSINE KINASE-1 | MIRROR-SYNDROME | PIGF | ENDOTHELIAL GROWTH-FACTOR | Enzyme-Linked Immunosorbent Assay | Humans | Fetofetal Transfusion - blood | Receptors, Cell Surface - blood | Case-Control Studies | Pregnancy | Endoglin | Pregnancy Proteins - blood | Antigens, CD - blood | Placenta Growth Factor | Adult | Female | Vascular Endothelial Growth Factor Receptor-1 - blood | Neovascularization, Physiologic | Antimitotic agents | Antineoplastic agents | Neovascularization
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6. Full Text Genetic origin and proportion of basal plate surface-lining cells in normal and abnormal pregnancies
by Richani, Karina, MD and Romero, Roberto, MD and Soto, Eleazar, MD and Nien, Jyh Kae, MD and Cushenberry, Enola, BS and Kim, Yeon Mee, MD and Espinoza, Jimmy, MD and Kim, Chong Jai, MD, PhD
Human Pathology, ISSN 0046-8177, 2007, Volume 38, Issue 2, pp. 269 - 275
Summary The human placenta is a transient organ, the villous surface of which is in direct contact with the maternal circulation during pregnancy. Thus, the... 
Pathology | Immunohistochemistry | Trophoblast | Placenta | Morphometry | Basal plate | Endothelium | endothelium | PLACENTAL BED | ACTIVATION | LASER-SCANNING MICROSCOPY | MEMBRANES | morphometry | PREECLAMPSIA | PATHOLOGY | SPIRAL ARTERIES | PATHOGENESIS | ENDOTHELIAL-CELLS | placenta | immunohistochemistry | INTRAUTERINE GROWTH RESTRICTION | basal plate | trophoblast | HYPERTENSION | Pre-Eclampsia - genetics | Humans | Fetus - metabolism | Male | Placenta - cytology | Polymerase Chain Reaction | Adult | Female | Placenta - chemistry | Pre-Eclampsia - metabolism | Trophoblasts - cytology | Fetus - chemistry | Endothelial Cells - chemistry | Trophoblasts - metabolism | Endothelial Cells - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - analysis | Gestational Age | Pre-Eclampsia - pathology | Fetus - cytology | Placenta - metabolism | Pregnancy | Cell Lineage | Amelogenin - genetics | Endothelial Cells - cytology | Adolescent | Alleles | Trophoblasts - chemistry | Genetic research | Pregnant women | Proteins | Hypertension | Polymerase chain reaction | Womens health | Preeclampsia | Deoxyribonucleic acid--DNA
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7. Full Text Toll-like receptor 4: A potential link between "danger signals," the innate immune system, and preeclampsia?
by Yeon, Mee Kim and Romero, Roberto and Seo, Young Oh and Chong, Jai Kim and Kilburn, Brian A and Armant, D. Randall and Jyh, Kae Nien and Gomez, Ricardo and Mazor, Moshe and Saito, Shigeru and Abrahams, Vikki M and Mor, Gil
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2005, Volume 193, Issue 3, pp. 921.e1 - 921.e8
Objective: Toll-like receptors (TLRs) recognize microbial ligands and host products that are released during tissue damage, the so-called "danger signals."... 
Pregnancy | Danger signal | Preeclampsia | Placental bed biopsy | Toll-like receptor-2 | Innate immunity | Toll-like receptor-4 | NF-Kappa B | Tumor necrosis factor-α | Toll-like receptor | Trophoblast migration | Immunohistochemistry | Toll-Like Receptor 2 | Toll-Like Receptor 4 | Trophoblasts - metabolism | Cross-Sectional Studies | Membrane Glycoproteins - metabolism | Placenta - immunology | Humans | Placenta - physiology | Receptors, Cell Surface - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cell Movement - drug effects | Toll-Like Receptors | Tumor Necrosis Factor-alpha - pharmacology | Trophoblasts - physiology | Lipopolysaccharides - pharmacology | Female | Pre-Eclampsia - metabolism | Pre-Eclampsia - immunology
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8. Full Text First trimester prediction of early onset preeclampsia using demographic, clinical, and sonographic data: a cohort study
by Caradeux, Javier and Serra, Ramón and Nien, Jyh‐Kae and Pérez‐Sepulveda, Alejandra and Schepeler, Manuel and Guerra, Francisco and Gutiérrez, Jorge and Martínez, Jaime and Cabrera, Cristián and Figueroa‐Diesel, Horacio and Soothill, Peter and Illanes, Sebastián E
Prenatal Diagnosis, ISSN 0197-3851, 08/2013, Volume 33, Issue 8, pp. 732 - 736
ABSTRACT Objective The aim of this research was to evaluate the performance of a predictive model for early onset preeclampsia (PE) during early gestation.... 
UTERINE ARTERY DOPPLER | RISK | MODEL | GENETICS & HEREDITY | OBSTETRICS & GYNECOLOGY | Prognosis | Humans | Risk Factors | Pre-Eclampsia - etiology | Pregnancy Trimester, First | Socioeconomic Factors | Pregnancy | Young Adult | Time Factors | Ultrasonography, Prenatal | Sensitivity and Specificity | Adult | Female | Early Diagnosis | Cohort Studies | Pre-Eclampsia - diagnosis | Hypertension | Preeclampsia | Diabetes
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9. Full Text A rapid MMP-8 bedside test for the detection of intra-amniotic inflammation identifies patients at risk for imminent preterm delivery
by Nien, Jyh Kae and Yoon, Bo Hyun and Espinoza, Jimmy and Kusanovic, Juan Pedro and Erez, Offer and Soto, Eleazar and Richani, Karina and Gomez, Ricardo and Hassan, Sonia and Mazor, Moshe and Edwin, Sam and Bahado-Singh, Ray and Romero, Roberto
American Journal of Obstetrics and Gynecology, ISSN 0002-9378, 2006, Volume 195, Issue 4, pp. 1025 - 1030
Matrix metalloproteinase-8 (MMP-8) is an enzyme that is released during neutrophil activation. MMP-8 amniotic fluid concentrations are elevated not only in... 
Intra-amniotic infection/inflammation | Chorioamnionitis | Intact membranes | Prematurity | Preterm labor | Point-of-care test | MMP-8 | Matrix metalloproteinase | prematurity | point-of-care test | intra-amniotic infection/inflammation | preterm labor | chorioamnionitis | AMNIOTIC-FLUID | PREGNANCY | OBSTETRICS & GYNECOLOGY | BRONCHOPULMONARY DYSPLASIA | intact membranes | PREMATURE RUPTURE | UREAPLASMA-UREALYTICUM | INTRAUTERINE INFECTION | matrix metalloproteinase | CEREBRAL-PALSY | LABOR | CLINICAL-SIGNIFICANCE | Pregnancy | Enzyme-Linked Immunosorbent Assay | Point-of-Care Systems | Amniotic Fluid - enzymology | Humans | Chorioamnionitis - diagnosis | Adult | Female | Risk | Infant, Newborn | Matrix Metalloproteinase 8 - analysis | Premature Birth - etiology | Medical examination | Pregnant women | Amniotic fluid | Diagnosis | Health aspects | Premature labor | Risk factors | Enzymes | Infants (Premature)
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10. Full Text Tackling Health Inequities in Chile: Maternal, Newborn, Infant, and Child Mortality Between 1990 and 2004
by Gonzalez, Rogelio and Requejo, Jennifer Harris and Nien, Jyh Kae and Merialdi, Mario and Bustreo, Flavia and Betran, Ana Pilar and Chile Maternal Newborn Child Hlth and Chile Maternal, Newborn, and Child Health Writing Group
American Journal of Public Health, ISSN 0090-0036, 07/2009, Volume 99, Issue 7, pp. 1220 - 1226
Objectives. We analyzed trends in maternal, newborn, and child mortality in Chile between 1990 and 2004, after the introduction of national interventions and... 
SURVIVAL 1 | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | INEQUALITIES | POOR | LATIN-AMERICA | TRENDS | REFORM | CARE | MEXICO | Humans | Risk Factors | Child, Preschool | Infant | Male | Chi-Square Distribution | Socioeconomic Factors | Maternal Mortality - trends | Female | Child Mortality - trends | Chile - epidemiology | Infant Mortality - trends | Infant, Newborn | Infants | Research | Mothers | Patient outcomes | Health care reform | Access to education | Multiple births | Family income | Health services | Mortality | Childrens health | Infant mortality | Children & youth | Maternal & child health | Womens health | Health care access | Public health | Inequality | Research and Practice
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11. Full Text Correlation between Maternal Characteristics during Early Pregnancy, Fetal Growth Rate and Newborn Weight in Healthy Pregnancies
by Caradeux, Javier and Serra, Ramón and Palmeiro, Yasna and Correa, Paula J and Valenzuela, Ignacio and Olguin, Jaime and Montenegro, Lazaro and Nien, Jyh Kae and Osorio, Eduardo and Illanes, Sebastián
Gynecologic and Obstetric Investigation, ISSN 0378-7346, 05/2016, Volume 81, Issue 3, pp. 202 - 206
Background: The objective of this study was to evaluate the association between maternal characteristics in early pregnancy and fetal growth (FG) and birth... 
Original Article | First trimester | Birth weight | Foetal growth | RISK-FACTORS | SIGNS | BIRTH-WEIGHT | CLASSIFICATION | PREECLAMPSIA | RESTRICTION | PREDICTION | OBSTETRICS & GYNECOLOGY | UTERINE ARTERY DOPPLER | GESTATIONAL-AGE | ASSOCIATION | Body Mass Index | Maternal Health | Body Weight | Prospective Studies | Humans | Fetal Weight | Fetal Development | Gestational Age | Pregnancy Trimester, First | Uterine Artery - physiology | Pregnancy | Birth Weight | Pulsatile Flow - physiology | Adult | Female | Infant, Newborn | Cohort Studies
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