Journal of Clinical Oncology, ISSN 0732-183X, 2014, Volume 32, Issue 13, pp. 1347 - 1355
PURPOSE: The (14;18) translocation constitutes both a genetic hallmark and critical early event in the natural history of follicular lymphoma (FL). However,...
Translocation, Genetic | International (English) | Prevalence | Europe | Humans | Middle Aged | Male | Biomarkers, Tumor | Case-Control Studies | Molecular Epidemiology | Chromosomes, Human, Pair 18 | Polymerase Chain Reaction | Lymphoma, Follicular | Adult | Chromosomes, Human, Pair 14 | Female | Aged | Cohort Studies | PROGENITOR CELLS | LOW-TUMOR-BURDEN | ONCOLOGY | B-CELL LYMPHOCYTOSIS | HEALTHY-INDIVIDUALS | CHRONIC LYMPHOCYTIC-LEUKEMIA | NON-HODGKIN-LYMPHOMA | MONOCLONAL GAMMOPATHY | SMOLDERING MULTIPLE-MYELOMA | SOMATIC MUTATIONS | UNDETERMINED SIGNIFICANCE MGUS | Europe - epidemiology | Polymerase Chain Reaction - methods | Biomarkers, Tumor - blood | Lymphoma, Follicular - epidemiology | Lymphoma, Follicular - blood | Lymphoma, Follicular - genetics | Biomarkers, Tumor - genetics | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Translocation, Genetic | International (English) | Prevalence | Europe | Humans | Middle Aged | Male | Biomarkers, Tumor | Case-Control Studies | Molecular Epidemiology | Chromosomes, Human, Pair 18 | Polymerase Chain Reaction | Lymphoma, Follicular | Adult | Chromosomes, Human, Pair 14 | Female | Aged | Cohort Studies | PROGENITOR CELLS | LOW-TUMOR-BURDEN | ONCOLOGY | B-CELL LYMPHOCYTOSIS | HEALTHY-INDIVIDUALS | CHRONIC LYMPHOCYTIC-LEUKEMIA | NON-HODGKIN-LYMPHOMA | MONOCLONAL GAMMOPATHY | SMOLDERING MULTIPLE-MYELOMA | SOMATIC MUTATIONS | UNDETERMINED SIGNIFICANCE MGUS | Europe - epidemiology | Polymerase Chain Reaction - methods | Biomarkers, Tumor - blood | Lymphoma, Follicular - epidemiology | Lymphoma, Follicular - blood | Lymphoma, Follicular - genetics | Biomarkers, Tumor - genetics | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
Nature Genetics, ISSN 1061-4036, 01/2014, Volume 46, Issue 11, pp. 1233 - 1238
Diffuse large B cell lymphoma (DLBCL) is the most common lymphoma subtype and is clinically aggressive. To identify genetic susceptibility loci for DLBCL, we...
COMMON VARIANTS | POPULATION | RAL GTPASES | NECROSIS-FACTOR TNF | GENETICS & HEREDITY | NON-HODGKIN-LYMPHOMA | CHRONIC LYMPHOCYTIC-LEUKEMIA | RISK | FOLLICULAR LYMPHOMA | CANCER | TUMORIGENESIS | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Likelihood Functions | Humans | Computational Biology | Genetic Loci - genetics | Polymorphism, Single Nucleotide - genetics | Genotype | Chromosome Mapping | Lymphoma, Large B-Cell, Diffuse - genetics | Quantitative Trait Loci - genetics | Quantitative trait loci | Genome-wide association studies | Genetic susceptibility | Lymphomas | Genetic aspects | B cells | Research | Health aspects | Risk factors | Studies | Confidence intervals | Genealogy | Genes | Genomics | Genomes | Chromosomes | Cancer | Meta-analysis | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
COMMON VARIANTS | POPULATION | RAL GTPASES | NECROSIS-FACTOR TNF | GENETICS & HEREDITY | NON-HODGKIN-LYMPHOMA | CHRONIC LYMPHOCYTIC-LEUKEMIA | RISK | FOLLICULAR LYMPHOMA | CANCER | TUMORIGENESIS | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Likelihood Functions | Humans | Computational Biology | Genetic Loci - genetics | Polymorphism, Single Nucleotide - genetics | Genotype | Chromosome Mapping | Lymphoma, Large B-Cell, Diffuse - genetics | Quantitative Trait Loci - genetics | Quantitative trait loci | Genome-wide association studies | Genetic susceptibility | Lymphomas | Genetic aspects | B cells | Research | Health aspects | Risk factors | Studies | Confidence intervals | Genealogy | Genes | Genomics | Genomes | Chromosomes | Cancer | Meta-analysis | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Journal of the National Cancer Institute Monographs, ISSN 1052-6773, 01/2014, Volume 2014, Issue 48, pp. 41 - 51
Background: Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are two subtypes of non-Hodgkin lymphoma. A number of studies have...
Cancer Research | Oncology | Life Style | Comorbidity | Humans | Middle Aged | Occupational Exposure | Risk Factors | Leukemia, Lymphocytic, Chronic, B-Cell - etiology | Australia - ethnology | Europe - epidemiology | Male | Leukemia, Lymphocytic, Chronic, B-Cell - epidemiology | Australia - epidemiology | Case-Control Studies | Europe - ethnology | Young Adult | North America - ethnology | Aged, 80 and over | Adult | Female | Aged | North America - epidemiology | Odds Ratio
Cancer Research | Oncology | Life Style | Comorbidity | Humans | Middle Aged | Occupational Exposure | Risk Factors | Leukemia, Lymphocytic, Chronic, B-Cell - etiology | Australia - ethnology | Europe - epidemiology | Male | Leukemia, Lymphocytic, Chronic, B-Cell - epidemiology | Australia - epidemiology | Case-Control Studies | Europe - ethnology | Young Adult | North America - ethnology | Aged, 80 and over | Adult | Female | Aged | North America - epidemiology | Odds Ratio
Journal Article
Journal of the National Cancer Institute, ISSN 0027-8874, 12/2015, Volume 107, Issue 12, p. djv279
BACKGROUND: Studies of related individuals have consistently demonstrated notable familial aggregation of cancer. We aim to estimate the heritability and...
Smoking - adverse effects | Kidney Neoplasms - genetics | Neoplasms - etiology | Tissue Array Analysis | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Urinary Bladder Neoplasms - genetics | Lung Neoplasms - etiology | Neoplasms - genetics | Adult | Female | Bone Neoplasms - genetics | Lung Neoplasms - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Testicular Neoplasms - genetics | Urinary Bladder Neoplasms - etiology | European Continental Ancestry Group - statistics & numerical data | Aged | Polymorphism, Single Nucleotide | Osteosarcoma - genetics | Asian Continental Ancestry Group - statistics & numerical data | Lymphoma, Large B-Cell, Diffuse - genetics
Smoking - adverse effects | Kidney Neoplasms - genetics | Neoplasms - etiology | Tissue Array Analysis | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | Male | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Urinary Bladder Neoplasms - genetics | Lung Neoplasms - etiology | Neoplasms - genetics | Adult | Female | Bone Neoplasms - genetics | Lung Neoplasms - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Testicular Neoplasms - genetics | Urinary Bladder Neoplasms - etiology | European Continental Ancestry Group - statistics & numerical data | Aged | Polymorphism, Single Nucleotide | Osteosarcoma - genetics | Asian Continental Ancestry Group - statistics & numerical data | Lymphoma, Large B-Cell, Diffuse - genetics
Journal Article
Nature Communications [E], ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 10933
Chronic lymphocytic leukemia (CLL) is a common lymphoid malignancy with strong heritability. To further understand the genetic susceptibility for CLL and...
Membrane Proteins | Adaptor Proteins, Signal Transducing | Genetic Predisposition to Disease | Genome-Wide Association Study | Apoptosis Regulatory Proteins | Humans | Serpins | European Continental Ancestry Group | Polymorphism, Single Nucleotide | Proto-Oncogene Proteins | T-Box Domain Proteins | Leukemia, Lymphocytic, Chronic, B-Cell | VARIANTS | BANK1 | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | RISK | CLASSIFICATION | FAS GENE-MUTATIONS | FOLLICULAR LYMPHOMA | PRIORITIZATION | COMMON VARIATION | IDENTIFICATION | European Continental Ancestry Group - genetics | Serpins - genetics | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | T-Box Domain Proteins - genetics | Bcl-2-Like Protein 11 | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - genetics | Chronic lymphatic leukemia | Leukemia | Agent orange | Genomes | Single-nucleotide polymorphism | Malignancy | Lymphatic leukemia | Chromosome 4 | Chromosome 3 | Loci | Chromosome 2 | Heritability | Apoptosis | Samfunnsmedisin, sosialmedisin: 801 | Community medicine, Social medicine: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Life Sciences | Hematology | Human health and pathology | Medical and Health Sciences | Medicin och hälsovetenskap
Membrane Proteins | Adaptor Proteins, Signal Transducing | Genetic Predisposition to Disease | Genome-Wide Association Study | Apoptosis Regulatory Proteins | Humans | Serpins | European Continental Ancestry Group | Polymorphism, Single Nucleotide | Proto-Oncogene Proteins | T-Box Domain Proteins | Leukemia, Lymphocytic, Chronic, B-Cell | VARIANTS | BANK1 | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY LOCI | RISK | CLASSIFICATION | FAS GENE-MUTATIONS | FOLLICULAR LYMPHOMA | PRIORITIZATION | COMMON VARIATION | IDENTIFICATION | European Continental Ancestry Group - genetics | Serpins - genetics | Membrane Proteins - genetics | Proto-Oncogene Proteins - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | T-Box Domain Proteins - genetics | Bcl-2-Like Protein 11 | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - genetics | Chronic lymphatic leukemia | Leukemia | Agent orange | Genomes | Single-nucleotide polymorphism | Malignancy | Lymphatic leukemia | Chromosome 4 | Chromosome 3 | Loci | Chromosome 2 | Heritability | Apoptosis | Samfunnsmedisin, sosialmedisin: 801 | Community medicine, Social medicine: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Life Sciences | Hematology | Human health and pathology | Medical and Health Sciences | Medicin och hälsovetenskap
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 10/2014, Volume 95, Issue 4, pp. 462 - 471
Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify...
SET | VARIANTS | CLASS-I | SNPS | RISK | UNIVERSITY | EXPRESSION | PEPTIDE | RESOURCE | TOOL | GENETICS & HEREDITY | Haplotypes - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Lymphoma, Follicular - genetics | Chromosomes, Human - genetics | Humans | Alleles | Polymorphism, Single Nucleotide - genetics | Biomarkers, Tumor - genetics | HLA Antigens - genetics | Case-Control Studies | Physiological aspects | Genome-wide association studies | Genetic aspects | Lymphatic diseases | Analysis | Report | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
SET | VARIANTS | CLASS-I | SNPS | RISK | UNIVERSITY | EXPRESSION | PEPTIDE | RESOURCE | TOOL | GENETICS & HEREDITY | Haplotypes - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Lymphoma, Follicular - genetics | Chromosomes, Human - genetics | Humans | Alleles | Polymorphism, Single Nucleotide - genetics | Biomarkers, Tumor - genetics | HLA Antigens - genetics | Case-Control Studies | Physiological aspects | Genome-wide association studies | Genetic aspects | Lymphatic diseases | Analysis | Report | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper
Journal Article
Environmental Health Perspectives, ISSN 0091-6765, 04/2016, Volume 124, Issue 4, pp. 396 - 405
BACKGROUND: Various occupations have been associated with an elevated NHL risk but results have been inconsistent across studies. OBJECTIVES: To investigate...
UNITED-STATES | NEW-ZEALAND | MALIGNANT-LYMPHOMAS | MANUFACTURING WORKERS | HEMATOPOIETIC CANCER | DEATH-CERTIFICATE | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY | FRANCISCO BAY AREA | SOFT-TISSUE SARCOMA | CANCER-MORTALITY | LYMPHOPROLIFERATIVE DISEASES | Humans | Middle Aged | Occupational Diseases - etiology | Risk Factors | Male | Lymphoma, Non-Hodgkin - epidemiology | Case-Control Studies | Adolescent | Aged, 80 and over | Textile Industry | Adult | Female | Aged | Agriculture | Barbering | Occupational Diseases - epidemiology | Lymphoma, Non-Hodgkin - etiology | Textile fabrics | Ionizing radiation | Research | Non-Hodgkin's lymphomas | Health aspects | Risk factors | Classification schemes | Farmers | Pesticides | Multiple myeloma | Estimates | Studies | Confidence intervals | Consortia | Hypotheses | Employment | Classification | Lymphomas | Wood preservatives | Index Medicus | Review
UNITED-STATES | NEW-ZEALAND | MALIGNANT-LYMPHOMAS | MANUFACTURING WORKERS | HEMATOPOIETIC CANCER | DEATH-CERTIFICATE | ENVIRONMENTAL SCIENCES | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TOXICOLOGY | FRANCISCO BAY AREA | SOFT-TISSUE SARCOMA | CANCER-MORTALITY | LYMPHOPROLIFERATIVE DISEASES | Humans | Middle Aged | Occupational Diseases - etiology | Risk Factors | Male | Lymphoma, Non-Hodgkin - epidemiology | Case-Control Studies | Adolescent | Aged, 80 and over | Textile Industry | Adult | Female | Aged | Agriculture | Barbering | Occupational Diseases - epidemiology | Lymphoma, Non-Hodgkin - etiology | Textile fabrics | Ionizing radiation | Research | Non-Hodgkin's lymphomas | Health aspects | Risk factors | Classification schemes | Farmers | Pesticides | Multiple myeloma | Estimates | Studies | Confidence intervals | Consortia | Hypotheses | Employment | Classification | Lymphomas | Wood preservatives | Index Medicus | Review
Journal Article
Nature Communications, ISSN 2041-1723, 02/2017, Volume 8, Issue 1, p. 14175
Several chronic lymphocytic leukaemia (CLL) susceptibility loci have been reported; however, much of the heritable risk remains unidentified. Here we perform a...
IMPUTATION | NETWORK | METAANALYSIS | CHROMATIN | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | RISK | LOCI | COMMON VARIATION | FEATURES | Genetic Predisposition to Disease | Genome-Wide Association Study | Chromosomes, Human - genetics | Humans | Middle Aged | B-Lymphocytes - physiology | Male | Chromosome Mapping | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Case-Control Studies | Young Adult | B-Lymphocytes - immunology | Adult | Female | Polymorphism, Single Nucleotide | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Antibody Formation - genetics | Leucèmia limfocítica crònica | Chronic lymphocytic leukemia | Càncer | Cancer | Life Sciences | Other | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
IMPUTATION | NETWORK | METAANALYSIS | CHROMATIN | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | RISK | LOCI | COMMON VARIATION | FEATURES | Genetic Predisposition to Disease | Genome-Wide Association Study | Chromosomes, Human - genetics | Humans | Middle Aged | B-Lymphocytes - physiology | Male | Chromosome Mapping | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Case-Control Studies | Young Adult | B-Lymphocytes - immunology | Adult | Female | Polymorphism, Single Nucleotide | Leukemia, Lymphocytic, Chronic, B-Cell - immunology | Antibody Formation - genetics | Leucèmia limfocítica crònica | Chronic lymphocytic leukemia | Càncer | Cancer | Life Sciences | Other | Clinical Medicine | Medical and Health Sciences | Cancer and Oncology | Klinisk medicin | Medicin och hälsovetenskap | Cancer och onkologi
Journal Article
International Journal of Cancer, ISSN 0020-7136, 07/2019, Volume 145, Issue 1, pp. 122 - 131
There is growing evidence of the protective role of the Mediterranean diet (MD) on cancer. However, no prospective study has yet investigated its influence on...
risk | Mediterranean diet | Europe | lymphoma | prospective studies | FRUITS | CYTOKINES | METAANALYSIS | NEOPLASMS | RATIONALE | PATTERNS | ONCOLOGY | NON-HODGKIN-LYMPHOMA | MALIGNANCIES | VEGETABLES | CONSUMPTION | Lymphomas | Research | Nutrition | Oncology, Experimental | Investigations | Cancer | Statistical analysis | Health risks | Risk | Hazards | Regression analysis | Lymphoma | Alcohols | Nutrition research | Regression models | Diet | Health risk assessment | Hodgkin's disease | Index Medicus | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
risk | Mediterranean diet | Europe | lymphoma | prospective studies | FRUITS | CYTOKINES | METAANALYSIS | NEOPLASMS | RATIONALE | PATTERNS | ONCOLOGY | NON-HODGKIN-LYMPHOMA | MALIGNANCIES | VEGETABLES | CONSUMPTION | Lymphomas | Research | Nutrition | Oncology, Experimental | Investigations | Cancer | Statistical analysis | Health risks | Risk | Hazards | Regression analysis | Lymphoma | Alcohols | Nutrition research | Regression models | Diet | Health risk assessment | Hodgkin's disease | Index Medicus | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Cancer and Oncology | Klinisk medicin | Cancer och onkologi
Journal Article