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1. Full Text Connective tissue diseases: Targeting type i interferon in systemic lupus erythematosus
by Niewold, Timothy B
Nature Reviews Rheumatology, ISSN 1759-4790, 07/2016, Volume 12, Issue 7, pp. 377 - 378
Monoclonal antibodies | Molecular targeted therapy | Care and treatment | Systemic lupus erythematosus | Health aspects | Innovations | Index Medicus
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2. Full Text When pregnancy tames the wolf
by Niewold, TB and Mehta-Lee, S
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 05/2019, Volume 216, Issue 5, pp. 1012 - 1013
A state of relative immunosuppression exists in normal pregnancy. In this issue of JEM, Hong et al. (https://doi.org/10.1084/jem.20190185) perform blood... 
MEDICINE, RESEARCH & EXPERIMENTAL | LUPUS | IMMUNOLOGY | I INTERFERON
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3. Full Text The genetics and molecular pathogenesis of systemic lupus erythematosus (SLE) in populations of different ancestry
by Goulielmos, George N and Zervou, Maria I and Vazgiourakis, Vassilis M and Ghodke-Puranik, Yogita and Garyfallos, Alexandros and Niewold, Timothy B
Gene, ISSN 0378-1119, 08/2018, Volume 668, pp. 59 - 72
Systemic lupus erythematosus (SLE; OMIM 152700) is a highly heterogeneous disorder, characterized by differences in autoantibody profile, serum cytokines, and... 
Ancestral background | Systemic lupus erythematosus (SLE) | Genetic association | Polymorphisms | RHEUMATOID-ARTHRITIS | I INTERFERON | TUMOR-NECROSIS-FACTOR | DNA EXONUCLEASE TREX1 | GENETICS & HEREDITY | TYROSINE-PHOSPHATASE PTPN22 | 3 ETHNIC-GROUPS | SINGLE-NUCLEOTIDE-POLYMORPHISM | STAGE RENAL-DISEASE | INTERFERON-ALPHA ACTIVITY | GENOME-WIDE ASSOCIATION | Lupus | Autoimmunity | Medical colleges | Autoantibodies | Genomics | Arthritis | Disease susceptibility | Biological response modifiers | Homeopathy | Materia medica and therapeutics | Systemic lupus erythematosus | Therapeutics | Interferon | Single nucleotide polymorphisms
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4. Full Text Interferon Alpha as a Primary Pathogenic Factor in Human Lupus
by Niewold, Timothy B
Journal of Interferon & Cytokine Research, ISSN 1079-9907, 12/2011, Volume 31, Issue 12, pp. 887 - 892
Interferon alpha (IFN-α) is a critical mediator of human systemic lupus erythematosus (SLE). This review will summarize evidence supporting the role for IFN-α... 
Reviews | RHEUMATOID-ARTHRITIS | IMMUNE-COMPLEXES | JUVENILE DERMATOMYOSITIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | SJOGRENS-SYNDROME | IMMUNOLOGY | CELL BIOLOGY | SYSTEMIC-LUPUS | IN-VIVO | FAMILIAL AGGREGATION | AUTOIMMUNE-DISEASE | GENOME-WIDE ASSOCIATION | IFN-ALPHA | Genetic Predisposition to Disease | Virus Diseases - immunology | Humans | Interferon Regulatory Factors - genetics | Lupus Erythematosus, Systemic - blood | Signal Transduction - genetics | Interferon-alpha - immunology | Polymorphism, Genetic | Signal Transduction - immunology | Interferon Regulatory Factors - immunology | Models, Immunological | Interferon-alpha - blood | Lupus Erythematosus, Systemic - genetics | Lupus Erythematosus, Systemic - immunology | Receptors, Immunologic - immunology | Receptors, Immunologic - genetics | Virus Diseases - genetics
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5. Full Text Immunogenetics of systemic lupus erythematosus: A comprehensive review
by Ghodke-Puranik, Yogita and Niewold, Timothy B
Journal of Autoimmunity, ISSN 0896-8411, 2015, Volume 64, pp. 125 - 136
Abstract Our understanding of the genetic basis of systemic lupus erythematosus has progressed rapidly in recent years. While many genetic polymorphisms have... 
Allergy and Immunology | Genetics | Interferon | Systemic lupus erythematosus | Autoimmune diseases | GENETIC POLYMORPHISMS | DENDRITIC CELLS | AICARDI-GOUTIERES SYNDROME | SUSCEPTIBILITY LOCI | IMMUNOLOGY | OF-FUNCTION VARIANT | DISEASE RISK VARIANT | NF-KAPPA-B | INTERFERON-ALPHA ACTIVITY | GENOME-WIDE ASSOCIATION | IFN-ALPHA | Genetic Predisposition to Disease | Major Histocompatibility Complex - genetics | Signal Transduction | Epigenesis, Genetic | Humans | Open Reading Frames | Regulatory Sequences, Nucleic Acid | Autoimmune Diseases - immunology | Lupus Erythematosus, Systemic - metabolism | Genetic Loci | Multifactorial Inheritance | Polymorphism, Genetic | Autoimmune Diseases - genetics | Immunogenetics | Animals | Lupus Erythematosus, Systemic - genetics | Lupus Erythematosus, Systemic - immunology | Interferon Type I - genetics | Interferon Type I - metabolism | Major Histocompatibility Complex - immunology | Autoimmune Diseases - metabolism | Lupus | Epigenetic inheritance | Genetic polymorphisms | autoimmune diseases | systemic lupus erythematosus | genetics | interferon
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6. Full Text Type I interferon in human autoimmunity
by Niewold, Timothy B
Frontiers in immunology, ISSN 1664-3224, 2014, Volume 5, p. 306
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7. Full Text Predictors of changes in disease activity among children with juvenile dermatomyositis enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Legacy Registry
by Challa, Divya and Crowson, Cynthia S and Niewold, Timothy B and Reed, Ann M and CARRA Legacy Registry and CARRA Legacy Registry Investigators and for the CARRA Legacy Registry Investigators
Clinical Rheumatology, ISSN 0770-3198, 4/2018, Volume 37, Issue 4, pp. 1011 - 1015
Determinants of changes in disease activity among patients with juvenile dermatomyositis (JDM) are unknown. Our objective was to develop predictive models to... 
Juvenile dermatomyositis | Disease activity | Medicine & Public Health | CARRA | Rheumatology | Predictors | POLYMYOSITIS | IDIOPATHIC INFLAMMATORY MYOPATHIES | RHEUMATOLOGY | ADULT | OUTCOME ASSESSMENT | MYOSITIS ASSESSMENT SCALE | RITUXIMAB | MUSCLE FUNCTION | TOOL | Viral antibodies | Medical research | Analysis | Dermatomyositis | Medicine, Experimental | Antibodies | Arthritis | Children | Diseases | Hydroxychloroquine | Pain | Myositis | Dysphagia | Regression analysis
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8. Full Text Advances in lupus genetics
by Niewold, Timothy B
Current Opinion in Rheumatology, ISSN 1040-8711, 09/2015, Volume 27, Issue 5, pp. 440 - 447
PURPOSE OF REVIEWThe field of systemic lupus erythematosus (SLE) genetics has been advancing rapidly in recent years. This review will summarize recent... 
Genetics | Interferon | Autoantibodies | Systemic lupus erythematosus | RHEUMATOID-ARTHRITIS | RHEUMATOLOGY | interferon | SEROLOGIC AUTOIMMUNITY | OF-FUNCTION VARIANT | systemic lupus erythematosus | genetics | ERYTHEMATOSUS PATIENTS | INCREASED SENSITIVITY | autoantibodies | DISEASE RISK VARIANT | AUTOIMMUNE-DISEASE | INTERFERON-ALPHA ACTIVITY | GENOME-WIDE ASSOCIATION | IFN-ALPHA | Genetic Predisposition to Disease | Genome-Wide Association Study | Lupus Erythematosus, Systemic - ethnology | Humans | Lupus Erythematosus, Systemic - genetics | Lupus Erythematosus, Systemic - immunology | African Americans | Interferon Type I - genetics | Polymorphism, Single Nucleotide | Interferon Type I - immunology
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9. Full Text Familial aggregation of childhood and adulthood-onset Systemic Lupus Erythematosus
by Sinicato, Nailú Angélica and de Oliveira, Luciana and Lapa, Aline Tamires and Postal, Mariana and de Oliveira Peliçari, Karina and Costallat, Lilian T L and Marini, Roberto and Gil-da-Silva-Lopes, Vera Lúcia and Niewold, Timothy B and Appenzeller, Simone
Arthritis care & research, ISSN 2151-464X, 05/2019
To assess the familial occurrence of systemic lupus erythematosus (SLE) in a large Brazilian cohort. Consecutive SLE patients were recruited, and stratified... 
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10. Full Text Kawasaki disease: How do you handle your antibodies?
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 01/2012, Volume 4, Issue 115
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11. Full Text Type I Interferon in Human Autoimmunity
by Timothy B. Niewold
2015, ISBN 2889193403
The type I interferon system plays a critical role in host defense in health, and a growing body of literature suggests that type I interferon is a critical... 
Multiple Sclerosis | autoimmune thyroid disease | systemic lupus erythematosus | systemic sclerosis | Sjogren's Syndrome | Interferons
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12. Full Text Cardiovascular disease: It's what you do that matters
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 11/2011, Volume 3, Issue 111
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13. Full Text All in the family
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 11/2011, Volume 3, Issue 107
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14. Full Text Asthma: One size doesn't fit all
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 10/2011, Volume 3, Issue 103
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15. Full Text Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
by Zhao, Jian and Wu, Hui and Khosravi, Melanie and Cui, Huijuan and Qian, Xiaoxia and Kelly, Jennifer A and Kaufman, Kenneth M and Langefeld, Carl D and Williams, Adrienne H and Comeau, Mary E and Ziegler, Julie T and Marion, Miranda C and Adler, Adam and Glenn, Stuart B and Alarcón-Riquelme, Marta E and BIOLUPUS Network, Network and GENLES Network, Network and Pons-Estel, Bernardo A and Harley, John B and Bae, Sang-Cheol and Bang, So-Young and Cho, Soo-Kyung and Jacob, Chaim O and Vyse, Timothy J and Niewold, Timothy B and Gaffney, Patrick M and Moser, Kathy L and Kimberly, Robert P and Edberg, Jeffrey C and Brown, Elizabeth E and Alarcon, Graciela S and Petri, Michelle A and Ramsey-Goldman, Rosalind and Vilá, Luis M and Reveille, John D and James, Judith A and Gilkeson, Gary S and Kamen, Diane L and Freedman, Barry I and Anaya, Juan-Manuel and Merrill, Joan T and Criswell, Lindsey A and Scofield, R. Hal and Stevens, Anne M and Guthridge, Joel M and Chang, Deh-Ming and Song, Yeong Wook and Park, Ji Ah and Lee, Eun Young and Boackle, Susan A and Grossman, Jennifer M and Hahn, Bevra H and Goodship, Timothy H. J and Cantor, Rita M and Yu, Chack-Yung and Shen, Nan and Tsao, Betty P and BIOLUPUS Network and GENLES Network
PLoS Genetics, ISSN 1553-7390, 05/2011, Volume 7, Issue 5, p. e1002079
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated with increased complement activation. Variants of genes encoding... 
DENSE DEPOSIT DISEASE | HEMOLYTIC-UREMIC SYNDROME | INFLUENCES RISK | POLYMORPHISMS | CFH | GENETICS & HEREDITY | MACULAR DEGENERATION | ALLOTYPIC VARIANT | HAPLOTYPE | MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS | Antigens, Neoplasm - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Hispanic Americans - genetics | Introns | Gene Frequency | Humans | Asian Continental Ancestry Group - genetics | African Americans - genetics | Genotype | Case-Control Studies | Lupus Erythematosus, Systemic - ethnology | Gene Deletion | Lupus Erythematosus, Systemic - genetics | Alleles | Biomarkers, Tumor - genetics | Polymorphism, Single Nucleotide | Chromosomes, Human, Pair 1 - genetics | Complement Factor H - genetics | Identification and classification | Chromosome deletion | Single nucleotide polymorphisms | Lupus | Research & development | Haplotypes | R&D | Disease | Pathogenesis | Genes | Genetics | Arthritis | Grants | Autoimmune diseases
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16. Full Text Cancer genetics: Decoding melanoma
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 05/2011, Volume 3, Issue 83
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17. Full Text Allergic to the cold
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 02/2012, Volume 4, Issue 119, pp. 119 - 119ec18
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18. Full Text Targeting type I interferon in systemic lupus erythematosus
by Niewold, TB
NATURE REVIEWS RHEUMATOLOGY, ISSN 1759-4790, 07/2016, Volume 12, Issue 7, pp. 377 - U13
Type I interferon (IFN) is an attractive therapeutic target in systemic lupus erythematosus (SLE), a notion bolstered by the positive results of a recent... 
RHEUMATOLOGY
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19. Full Text Thinking globally about asthma
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 09/2011, Volume 3, Issue 99, pp. 99 - 99ec146
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20. Full Text Channeling cognitive performance
by Niewold, Timothy B
Science Translational Medicine, ISSN 1946-6234, 07/2011, Volume 3, Issue 91, pp. 91 - 91ec110
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