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Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7572, pp. 263 - 267
Colorectal cancer is the third most common cancer worldwide, with 1.2 million patients diagnosed annually. In late-stage colorectal cancer, the most commonly... 
PANITUMUMAB | THERAPY | MULTIDISCIPLINARY SCIENCES | SEQUENCE | ACQUIRED-RESISTANCE | SOMATIC MUTATION | IDENTIFICATION | GENE COPY NUMBER | ACTIVATING MUTATIONS | BREAST | INSIGHTS | Receptor, Epidermal Growth Factor - genetics | Receptor, ErbB-2 - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Colorectal Neoplasms - genetics | Genomics | Humans | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Cetuximab - therapeutic use | Molecular Targeted Therapy | Receptor, Fibroblast Growth Factor, Type 1 - genetics | MAP Kinase Kinase 1 - genetics | Colorectal Neoplasms - drug therapy | Female | Antineoplastic Agents - pharmacology | Insulin Receptor Substrate Proteins - genetics | Colorectal Neoplasms - metabolism | Antibodies, Monoclonal - pharmacology | Cetuximab - pharmacology | DNA Copy Number Variations - genetics | Mutation - genetics | Genome, Human - genetics | Receptor, Epidermal Growth Factor - chemistry | Xenograft Model Antitumor Assays | Drug Resistance, Neoplasm - genetics | Exome - genetics | Animals | Receptor, Platelet-Derived Growth Factor alpha - genetics | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Drug Resistance, Neoplasm - drug effects | Care and treatment | Gene mutations | Colorectal cancer | Drug metabolism | Genetic aspects | Identification and classification | Health aspects | Proteins | Epidermal growth factor | Genes | Clinical trials | Mutation | Kinases | Cancer therapies | Tumors | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2013, Volume 45, Issue 12, pp. 1470 - 1473
Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 1093 - 11
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 10/2015, Volume 11, Issue 10
  Recent improvements in next-generation sequencing of tumor samples and the ability to identify somatic mutations at low allelic fractions have opened the way... 
Trees | Studies | Hypotheses | Phylogenetics | Mutation | Experiments | Methods | Cancer | Genetic algorithms
Journal Article
Nature, ISSN 0028-0836, 06/2019, Volume 570, Issue 7761, pp. 385 - 389
Journal Article
Cell, ISSN 0092-8674, 11/2017, Volume 171, Issue 6, pp. 1284 - 1300.e21
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 6, pp. 1501 - 1510
Journal Article
Bioinformatics, ISSN 1367-4803, 03/2013, Volume 29, Issue 5, pp. 647 - 648
Advances in sequencing technology have greatly reduced the costs incurred in collecting raw sequencing data. Academic laboratories and researchers therefore... 
MUTATIONS | GENOMES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ANNOTATION | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | Software | Internet | Mutation | Neoplasms - genetics | Genomics - methods | Humans | Index Medicus | Alterations | Genes | Tools | Texts | Biological | Assessments | Sequencing | Bioinformatics | Applications Notes
Journal Article