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Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7579, pp. 477 - 483
At least 120 non-olfactory G-protein-coupled receptors in the human genome are 'orphans' for which endogenous ligands are unknown, and many have no selective... 
EXTRACELLULAR ACIDIFICATION | ACTIVATION | COMPLEX | OGR1 | PROTEIN-COUPLED RECEPTOR | MULTIDISCIPLINARY SCIENCES | CAMP ACCUMULATION | SMOOTH-MUSCLE-CELLS | EXPRESSION | CANCER | Anti-Anxiety Agents - metabolism | Lorazepam - pharmacology | Memory - drug effects | Receptors, G-Protein-Coupled - metabolism | Humans | Anti-Anxiety Agents - analysis | Male | Receptors, G-Protein-Coupled - agonists | Lorazepam - analysis | Benzyl Alcohols - pharmacology | HEK293 Cells | Anti-Anxiety Agents - chemistry | Female | Triazines - chemistry | Allosteric Regulation - drug effects | Benzyl Alcohols - chemistry | Triazines - metabolism | Triazines - pharmacology | Lorazepam - metabolism | Anti-Anxiety Agents - pharmacology | Models, Molecular | Drug Discovery | Mice, Knockout | Triazines - analysis | Fear | Animals | Receptors, G-Protein-Coupled - deficiency | Signal Transduction - drug effects | Benzyl Alcohols - analysis | Allosteric Site | Lorazepam - chemistry | Receptors, G-Protein-Coupled - antagonists & inhibitors | Conditioning, Classical | Benzyl Alcohols - metabolism | Ligands | Mice | Receptors, G-Protein-Coupled - chemistry | Physiological aspects | Cell receptors | Identification and classification | Ligands (Biochemistry) | Proteins | Yeast | Rodents | Physiology | Genomes | Kinases | proton-sensing | virtual screening | GPR68 | GPR65 | positive allosteric modulator (PAM) | functional selectivity | allosteric modulator
Journal Article
Neuron, ISSN 0896-6273, 06/2018, Volume 98, Issue 6, pp. 1124 - 1132.e7
Neuronal activity regulates the transcription and translation of the immediate-early gene Arc/Arg3.1, a key mediator of synaptic plasticity.... 
reversal learning | Arc/Arg3.1 | AMPA receptor trafficking | mGluR-LTD | synaptic plasticity | Barnes maze | Arc/Arg3.1 turnover | cognitive flexibility | ubiquitin | GAG PROTEIN | RNA | LONG-TERM DEPRESSION | GENE-EXPRESSION | MGLUR-LTD | ARC/ARG3.1 | DEGRADATION | RECEPTOR | TRANSLATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | Long-Term Synaptic Depression - genetics | Long-Term Synaptic Depression - physiology | Reversal Learning - physiology | Cytoskeletal Proteins - genetics | Receptors, Metabotropic Glutamate - metabolism | RNA, Messenger - metabolism | Nerve Tissue Proteins - genetics | Gene Knock-In Techniques | Protein Transport | Spatial Learning - physiology | Nerve Tissue Proteins - metabolism | Neuronal Plasticity - genetics | Ubiquitination | Animals | Time Factors | Proteolysis | Cognition - physiology | Cytoskeletal Proteins - metabolism | Mice | Mutation | Receptors, AMPA - metabolism | Ubiquitin | Medical colleges | Genetic transcription | Neurophysiology | Transcription | Neurons | Memory | Spatial discrimination learning | Spatial discrimination | Cognitive ability | Gene expression | Variance analysis | ARC protein | Learning | Proteins | Plasticity (synaptic) | Protein synthesis | Reversal learning | Protein expression | Software | Glutamic acid receptors (metabotropic) | Spatial memory | Arg3.1 | Arc | Arg3.1 turnover
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 12/2019, Volume 129, Issue 12, p. 5462
Angelman syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability, lack of speech, ataxia, EEG abnormalities, and epilepsy.... 
Medicine, Experimental | Medical research | Marijuana | Analysis | Epilepsy
Journal Article
The British journal of psychiatry : the journal of mental science, ISSN 0007-1250, 01/2019, Volume 214, Issue 1, pp. 42 - 51
Journal Article
Journal Article
Journal of Psychopharmacology, ISSN 0269-8811, 4/2018, Volume 32, Issue 4, pp. 408 - 415
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2013, Volume 72, pp. 187 - 196
Journal Article
Carcinogenesis, ISSN 0143-3334, 3/2009, Volume 30, Issue 3, pp. 397 - 407
Journal Article