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Trends in Endocrinology & Metabolism, ISSN 1043-2760, 03/2019, Volume 30, Issue 3, pp. 163 - 176
Overweight and obesity pose significant health problems globally, and are causatively linked to metabolic dysregulation. The hypothalamus integrates neural,... 
unfolded protein response | neuropeptides | proopiomelanocortin | inflammation | obesity | endoplasmic reticulum stress | POMC NEURONS | LIPID-ACCUMULATION | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | HEPATIC INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | CONNECTS ER STRESS | DIET-INDUCED OBESITY | NF-KAPPA-B | LEPTIN RESISTANCE | TRANSMEMBRANE PROTEIN
Journal Article
Endocrinology, ISSN 0013-7227, 09/2007, Volume 148, Issue 9, pp. 4191 - 4200
Recent evidence demonstrated that posttranslational processing of neuropeptides is critical in the pathogenesis of obesity. Leptin or other physiological... 
NUCLEUS-TRACTUS-SOLITARIUS | MELANOCYTE-STIMULATING HORMONE | MELANOCORTIN-3/4 RECEPTOR STIMULATION | MESSENGER-RNA | NHLH2 TRANSCRIPTION FACTOR | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | CENTRAL-NERVOUS-SYSTEM | CAUDAL BRAIN-STEM | RAT-BRAIN | BETA-ENDORPHIN
Journal Article
Frontiers in Neuroendocrinology, ISSN 0091-3022, 2010, Volume 31, Issue 2, pp. 134 - 156
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2009, Volume 4, Issue 12, pp. e8322 - e8322
Sirt1 is an evolutionarily conserved NAD+ dependent deacetylase involved in a wide range of processes including cellular differentiation, apoptosis, as well as... 
ACTIVATED PROTEIN-KINASE | ENERGY HOMEOSTASIS | HIGH-FAT DIET | IN-VIVO | TRANSCRIPTION | BIOLOGY | GENE-EXPRESSION | PROTHYROTROPIN-RELEASING HORMONE | SIRNA DELIVERY | CELL-SURVIVAL | CALORIE RESTRICTION | Sirtuin 1 - metabolism | Ribosomal Protein S6 Kinases - metabolism | Signal Transduction | Melanocortins - metabolism | Arcuate Nucleus of Hypothalamus - metabolism | Rats | Rats, Sprague-Dawley | Feeding Behavior - physiology | Nerve Tissue Proteins - metabolism | Pro-Opiomelanocortin - metabolism | Animals | Hypothalamus - metabolism | Forkhead Transcription Factors - metabolism | Models, Biological | Receptors, Melanocortin - metabolism | Hypothalamus - enzymology | Cell Line, Tumor | Models, Animal | Mice | Acetylation | Body Weight - physiology | Energy Metabolism - physiology | Physiological aspects | Brain | Anorexia nervosa | Cell differentiation | Body weight | Laboratories | Homeostasis | Biochemistry | Hypothalamus | Kinases | Tissues | Medical schools | Proteins | Cell growth | FOXO1 protein | Transgenic animals | Rodents | Aging | Forkhead protein | Inhibition | Food | Encephalitis | Fasting | Medical treatment | Aging (artificial) | Melanocortin | siRNA | Pharmacology | Gene expression | Metabolism | Body weight gain | SIRT1 protein | Medicine | NAD | Energy balance | Signaling | Hospitals | Food intake | Energy efficiency | Diabetes | Molecular biology | Alzheimers disease | Endocrinology | Metabolic disorders | Apoptosis
Journal Article
Frontiers in Bioscience, ISSN 1093-9946, 05/2007, Volume 12, Issue 9, pp. 3554 - 3565
Journal Article
Endocrinology, ISSN 0013-7227, 09/2007, Volume 148, Issue 9, pp. 4191 - 4200
Recent evidence demonstrated that posttranslational processing of neuropeptides is critical in the pathogenesis of obesity. Leptin or other physiological... 
Journal Article
Endocrinology, ISSN 0013-7227, 09/2007, Volume 148, Issue 9, pp. 4191 - 4200
Journal Article