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Genes and Development, ISSN 0890-9369, 02/2011, Volume 25, Issue 4, pp. 350 - 362
Repair of dsDNA breaks requires processing to produce 3'-terminated ssDNA. We biochemically reconstituted DNA end resection using purified human proteins:... 
BLM helicase | DNA2 nuclease | DNA break repair | EXO1 nuclease | DNA end resection | Homologous recombination | NUCLEASE ACTIVITY | BLOOMS-SYNDROME HELICASE | HUMAN EXONUCLEASE 1 | ESCHERICHIA-COLI | MISMATCH REPAIR | DEVELOPMENTAL BIOLOGY | DOUBLE-STRAND BREAK | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | homologous recombination | GENETICS & HEREDITY | MRE11 NUCLEASE | MITOTIC RECOMBINATION | RECQ HELICASE | RecQ Helicases - metabolism | Humans | DNA Repair Enzymes - genetics | Replication Protein A - physiology | Multiprotein Complexes - genetics | RecQ Helicases - genetics | DNA Repair - genetics | DNA Breaks, Double-Stranded | DNA Breaks, Single-Stranded | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Multiprotein Complexes - metabolism | Replication Protein A - genetics | DNA Repair Enzymes - metabolism | Cell Cycle Proteins - genetics | Exodeoxyribonucleases - genetics | Nuclear Proteins - genetics | DNA Helicases - genetics | RecQ Helicases - physiology | DNA Repair Enzymes - physiology | DNA-Binding Proteins - physiology | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Replication Protein A - metabolism | DNA-Binding Proteins - genetics | Multiprotein Complexes - physiology | DNA Helicases - metabolism | Models, Biological | Exodeoxyribonucleases - metabolism | Exodeoxyribonucleases - physiology | Nuclear Proteins - physiology | In Vitro Techniques | Cell Cycle Proteins - physiology | DNA Helicases - physiology | Protein Binding - physiology | Research Paper
Journal Article
Journal Article
Journal Article
Biophysical Journal, ISSN 0006-3495, 01/2010, Volume 98, Issue 3, p. 66
Journal Article
Genes & Development, ISSN 0890-9369, 02/2011, Volume 25, Issue 4, pp. 350 - 362
Repair of dsDNA breaks requires processing to produce 3'-terminated ssDNA. We biochemically reconstituted DNA end resection using purified human proteins:... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2009, Volume 106, Issue 9, p. 3077
  Saccharomyces cerevisiae Rad52 performs multiple functions during the recombinational repair of double-stranded DNA (dsDNA) breaks (DSBs). It mediates... 
Proteins | Yeast | Biochemistry | Catalysis | Deoxyribonucleic acid--DNA | Cells
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2009, Volume 106, Issue 9, pp. 3077 - 3082
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2019, Volume 116, Issue 21, pp. 10360 - 10365
Lipoprotein lipase (LPL) plays a central role in triglyceride (TG) metabolism. By catalyzing the hydrolysis of TGs present in TG-rich lipoproteins (TRLs), LPL... 
X-ray crystallography | LPL | lipase | GPIHBP1 | INACTIVATION | MULTIDISCIPLINARY SCIENCES | TRIGLYCERIDE-RICH LIPOPROTEINS | BINDING PROTEIN-1 | RISK | ANGPTL4 | DEFICIENCY | Physiological aspects | Lipoprotein lipase | Structure | Binding proteins | Proteins | Lipoproteins | Inhibitors | Homology | Lipids | Glycosylphosphatidylinositol | Lipase | Metabolism | Lipolysis | Crystal structure
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2008, Volume 105, Issue 44, p. 16906
  The error-free repair of double-stranded DNA breaks by homologous recombination requires processing of broken ends. These processed ends are substrates for... 
Proteins | Biochemistry | DNA repair | Chromosomes | Deoxyribonucleic acid--DNA
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 34, pp. 28727 - 28737
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2007, Volume 282, Issue 42, pp. 30776 - 30784
The Saccharomyces cerevisiae Tid1 protein is important for the recombinational repair of double-stranded DNA breaks during meiosis. Tid1 is a member of... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2004, Volume 279, Issue 21, pp. 21957 - 21965
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/2007, Volume 282, Issue 42, pp. 30776 - 30784
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 09/2003, Volume 31, Issue 18, p. 5275
  ICP8, the herpes simplex virus type-1 encoded single-strand DNA (ssDNA)-binding protein, promotes the assimilation of a single-stranded DNA molecule into a... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2003, Volume 100, Issue 18, pp. 10201 - 10206
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2003, Volume 100, Issue 18, p. 10201
  The repair of double-strand DNA breaks by homologous recombination is essential for the maintenance of genome stability. In herpes simplex virus 1,... 
Proteins | Herpes viruses | Biochemistry | DNA repair
Journal Article
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