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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2016, Volume 113, Issue 16, pp. 4476 - 4481
Inhibition of the vascular endothelial growth factor (VEGF) pathway has failed to improve overall survival of patients with glioblastoma (GBM). We previously... 
Anti-angiogenic therapy | Macrophage polarization | Tumor microenvironment | Microglia reprogramming | Anti-tumor immunity | anti-angiogenic therapy | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | macrophage polarization | RANDOMIZED-TRIAL | ANGIOPOIETIN-2 | CANCER | THERAPY | microglia reprogramming | TIE2-EXPRESSING MONOCYTES | BLOOD-VESSELS | TUMOR-ASSOCIATED MACROPHAGES | tumor microenvironment | NORMALIZATION | anti-tumor immunity | ENDOTHELIAL GROWTH-FACTOR | Macrophages - pathology | Antibodies, Bispecific - pharmacology | Vesicular Transport Proteins - metabolism | Humans | Neoplasm Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Neoplasm Proteins - metabolism | Neoplasms, Experimental - pathology | Xenograft Model Antitumor Assays | Macrophages - metabolism | Vesicular Transport Proteins - antagonists & inhibitors | Animals | Antibodies, Neoplasm - pharmacology | Ribonuclease, Pancreatic - metabolism | Glioblastoma - pathology | Cell Line, Tumor | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Mice | Neoplasms, Experimental - metabolism | Glioblastoma - drug therapy | Ribonuclease, Pancreatic - antagonists & inhibitors | Neoplasms, Experimental - drug therapy | Viral antibodies | Care and treatment | Antibodies | Physiological aspects | Models | Macrophages | Vascular endothelial growth factor | Health aspects | Glioblastoma multiforme | Genotype & phenotype | Survival analysis | Protein expression | Cells | Tumors | Cancer | Index Medicus | Biological Sciences
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2016, Volume 55, Issue 40, pp. 12440 - 12444
The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study cellular events with greater precision and complexity. In this work,... 
CRISPR | DNA cleavage | nucleic acids | photochemistry | gene technology | TARGET | ENDONUCLEASE | EXPRESSION | CHEMISTRY, MULTIDISCIPLINARY | GENOME | Nucleotide sequencing | RNA | Genes | DNA sequencing | Protectors | Nucleotide sequence | Photoactivation | Labels | Marking | Ribonucleic acid--RNA | Light effects | Gene sequencing | Complexity | Imaging | Compatibility | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Academic Pediatrics, ISSN 1876-2859, 09/2019, Volume 19, Issue 7, pp. 787 - 792
Due to increasing popularity, our hospital began considering distributing cardboard boxes combined with safe sleep education to new mothers. As a first step in... 
infant sleep | SUID | cardboard box | Medical colleges | Usage | Infants | Sleep | Index Medicus
Journal Article
Journal of Women's Health, ISSN 1540-9996, 03/2019
Background: Sex is a biological variable linked to our chromosomal complement, while gender refers to one's personal identification as influenced by social,... 
Journal Article
Angewandte Chemie (International ed. in English), ISSN 1433-7851, 9/2016, Volume 55, Issue 40, pp. 12440 - 12444
The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study cellular events with greater precision and complexity. We developed a... 
CRISPR | Nucleic acids | Gene technology | DNA Cleavage | Photochemistry
Journal Article
Cancer Research, ISSN 0008-5472, 07/2016, Volume 76, Issue 14_Supplement, pp. LB - 347-LB-347
OBJECTIVE: We aimed to enhance the efficacy of anti-VEGF therapy in glioblastoma (GBM) through additional inhibition of Angiopoietin-2 (Ang-2), a potential... 
Journal Article
Angewandte Chemie, ISSN 0044-8249, 09/2016, Volume 128, Issue 40, p. 12628
  The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study cellular events with greater precision and complexity. In this... 
CRISPR | Protectors | Nucleotide sequence | Photoactivation | Labels | Marking | Ribonucleic acid--RNA | Light effects | Gene sequencing | Complexity | Imaging | Compatibility | Deoxyribonucleic acid--DNA
Journal Article
Angewandte Chemie, ISSN 0044-8249, 09/2016, Volume 128, Issue 40, pp. 12628 - 12632
The ability to remotely trigger CRISPR/Cas9 activity would enable new strategies to study cellular events with greater precision and complexity. In this work,... 
CRISPR | Nucleinsäuren | Gentechnik | Photochemie | DNA-Spaltung | RNA | Nucleotide sequencing | DNA sequencing | Ribonucleic acids | Protectors | Deoxyribonucleic acid | Imaging | Strategy | Marking | Compatibility | Gene sequencing
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 06/2013, Volume 26, Issue 6, pp. 878 - 895
Journal Article
TOXICOLOGICAL SCIENCES, ISSN 1096-6080, 06/2019, Volume 169, Issue 2, pp. 553 - 566
Prediction of human response to chemical exposures is a major challenge in both pharmaceutical and toxicological research. Transcriptomics has been a powerful... 
liver injury | S1500+geneset | ACTIVATED RECEPTOR-GAMMA | benchmark concentration analysis | toxicogenomics | DNA-DAMAGE | TROVAFLOXACIN | TROGLITAZONE | RISK | HepaRG cells | HEPATOCYTE-LIKE CELLS | LUNG-CANCER | METABOLISM | LEVOFLOXACIN | TOXICOLOGY | HEPATOTOXICITY | high-throughput sequencing
Journal Article
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