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F1000Research, ISSN 2046-1402, 2016, Volume 5, p. 389
In this article, we first present a summary of the general assumptions about Down syndrome (DS) still to be found in the literature. We go on to show how new... 
Behavioral Neuroscience | Developmental & Pediatric Neurology | Medical Genetics | Neurogenetics | Cognitive Neurology & Dementia | Cognitive Neuroscience | Neurodevelopment | Neural Homeostasis | Neurobiology of Disease & Regeneration
Journal Article
JAMA Neurology, ISSN 2168-6149, 02/2019, Volume 76, Issue 2, pp. 152 - 160
IMPORTANCE This work quantifies the fatal burden of dementia associated with Alzheimer disease in individuals with Down syndrome (DS). OBJECTIVE To explore the... 
SURVIVAL | ALZHEIMER-DISEASE | COGNITIVE DECLINE | CLINICAL NEUROLOGY | AGE | Health care | Elderly people | Neurodegenerative diseases | Health | Epilepsy | Mortality | Hazards | Down syndrome | Carriers | Consortia | Down's syndrome | Apolipoprotein E | Correlation analysis | Dementia disorders | Data collection | Collection | Death | Fatalities | Adults | Diagnosis | Alzheimer's disease | Age | Genotypes | Dementia | Online First | Original Investigation | Research
Journal Article
Journal Article
Science, ISSN 0036-8075, 9/2005, Volume 309, Issue 5743, pp. 2033 - 2037
Journal Article
F1000Research, ISSN 2046-1402, 2016, Volume 5, p. 876
Down syndrome (DS), which arises from trisomy of chromosome 21, is associated with deposition of large amounts of amyloid within the central nervous system.... 
Medical Genetics | Neuronal & Glial Cell Biology | Neurogenetics | Animal Genetics | Cognitive Neurology & Dementia | Immune Response | Cognitive Neuroscience | Cerebrovascular Disease | Epidemiology | Neurobiology of Disease & Regeneration | Cellular Death & Stress Responses
Journal Article
Journal Article
Nature, ISSN 0028-0836, 06/2010, Volume 465, Issue 7299, pp. 813 - 817
Down's syndrome (DS) is a genetic disorder caused by full or partial trisomy of human chromosome 21 and presents with many clinical phenotypes including a... 
CADHERIN | APOPTOSIS | ADAMTS-1 | ENDOTHELIAL-CELL PROLIFERATION | GENE | VEGF | MULTIDISCIPLINARY SCIENCES | GROWTH | DSCR1 | MICE | ETS2 | Transcriptional Regulator ERG | Neoplasm Transplantation | Oncogene Proteins - genetics | Cell Adhesion Molecules - genetics | Chromosomes, Mammalian - genetics | Humans | Cell Adhesion Molecules - antagonists & inhibitors | Male | Down Syndrome - physiopathology | Vascular Endothelial Growth Factor A - metabolism | Immunoglobulins - genetics | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Carcinoma, Lewis Lung - blood supply | Neovascularization, Pathologic - pathology | Immunoglobulins - metabolism | Carcinoma, Lewis Lung - complications | Proto-Oncogene Protein c-ets-2 - genetics | Down Syndrome - complications | Female | Proto-Oncogene Protein c-ets-2 - metabolism | Vascular Endothelial Growth Factor A - pharmacology | ADAMTS1 Protein | Disease Models, Animal | Gene Dosage - genetics | Melanoma, Experimental - blood supply | Oncogene Proteins - metabolism | Melanoma, Experimental - complications | Melanoma, Experimental - pathology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Cell Adhesion Molecules - metabolism | Carrier Proteins - genetics | ADAM Proteins - metabolism | Animals | Carcinoma, Lewis Lung - genetics | Carrier Proteins - metabolism | Melanoma, Experimental - genetics | Trisomy - genetics | Down Syndrome - genetics | Carcinoma, Lewis Lung - pathology | Neovascularization, Pathologic - genetics | Mice | Transcription Factors | ADAM Proteins - genetics | Complications and side effects | Physiological aspects | Development and progression | Genetic aspects | Down syndrome | Neovascularization | Research | Risk factors | Tumors | Proteins | Studies | Angiogenesis | Genotype & phenotype | Rodents | Blood vessels | Genetic engineering | Gene therapy | Vascular endothelial growth factor
Journal Article