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1. Full Text Phenomenological 0-Dimensional Combustion Model for Spark-Ignition Natural Gas Engine Equipped with Pre-Chamber
by Hiraoka, Kenji, author and Nomura, Kazutoshi, author and Yuuki, Akihiro, author and Oda, Yuji, author and Kameyama, Toshiyuki, author
SAE technical paper series, Volume 2016-01-0556.
3D CFD (Computational Fluid Dynamics) is widely used as a useful design tool because of its efficiency in engine development. In contrast, the computational... 
Combustion and combustion processes | CAD, CAM, and CAE | Turbulence | Spark ignition engines | Natural gas
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2. Full Text Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia
by Khera, Amit V., MD and Won, Hong-Hee, PhD and Peloso, Gina M., PhD and Lawson, Kim S., MS and Bartz, Traci M., MS and Deng, Xuan, MSc and van Leeuwen, Elisabeth M and Natarajan, Pradeep, MD, MMSc and Emdin, Connor A., HBSc and Bick, Alexander G., PhD and Morrison, Alanna C., PhD and Brody, Jennifer A., BA and Gupta, Namrata, PhD and Nomura, Akihiro, MD and Kessler, Thorsten, MD and Duga, Stefano, PhD and Bis, Joshua C., PhD and van Duijn, Cornelia M., PhD and Cupples, L. Adrienne, PhD and Psaty, Bruce, MD, PhD and Rader, Daniel J., MD and Danesh, John, DPhil and Schunkert, Heribert, MD and McPherson, Ruth, MD and Farrall, Martin, MD and Watkins, Hugh, MD, PhD and Lander, Eric, PhD and Wilson, James G., MD and Correa, Adolfo, MD, PhD and Boerwinkle, Eric, PhD and Merlini, Piera Angelica, MD and Ardissino, Diego, MD and Saleheen, Danish, MBBS, PhD and Gabriel, Stacey, PhD and Kathiresan, Sekar, MD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 67, Issue 22, pp. 2578 - 2589
Abstract Background Approximately 7% of American adults have severe hypercholesterolemia (untreated low-density lipoprotein [LDL] cholesterol ≥190 mg/dl),... 
Cardiovascular | Internal Medicine | coronary artery disease | gene sequencing | genetics | low-density lipoprotein cholesterol | POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | VARIANTS | AUTOSOMAL-DOMINANT HYPERCHOLESTEROLEMIA | PREVALENCE | GUIDANCE | HEART | MUTATIONS | SPECTRUM | ASSOCIATION | LDLR | Receptors, LDL - genetics | Humans | Middle Aged | Hyperlipoproteinemia Type II - diagnosis | Male | Proprotein Convertase 9 - genetics | Apolipoprotein B-100 - genetics | Case-Control Studies | Genetic Variation | Cholesterol, LDL - blood | Female | Heterozygote | Coronary Artery Disease - epidemiology | Sequence Analysis | Cohort Studies | Hypercholesterolemia - epidemiology | Hyperlipoproteinemia Type II - genetics | Medical colleges | Care and treatment | Low density lipoproteins | Genes | Coronary heart disease | Population genetics | Epidemiology | Blood | Hypercholesterolemia | Analysis and chemistry | Atherosclerosis | Genetic research | Genetic aspects | Diagnosis | Research institutes | Cardiology | Trans fatty acids | Heart attacks | Cardiovascular disease | Lipids | Apolipoproteins | Low density lipoprotein | Cholesterol | Proteins | Studies | Confidence intervals | Consortia | Algorithms | Coronary vessels | Population | Mutation | Deoxyribonucleic acid--DNA
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3. Full Text Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial
by Kobayashi, Tohru, Dr and Saji, Tsutomu, Prof and Otani, Tetsuya, MD and Takeuchi, Kazuo, Prof and Nakamura, Tetsuya, MD and Arakawa, Hirokazu, Prof and Kato, Taichi, MD and Hara, Toshiro, Prof and Hamaoka, Kenji, Prof and Ogawa, Shunichi, Prof and Miura, Masaru, MD and Nomura, Yuichi, MD and Fuse, Shigeto, MD and Ichida, Fukiko, Prof and Seki, Mitsuru, MD and Fukazawa, Ryuji, MD and Ogawa, Chitose, MD and Furuno, Kenji, MD and Tokunaga, Hirohide, MD and Takatsuki, Shinichi, MD and Hara, Shinya, MD and Morikawa, Akihiro, Prof and RAISE Study Grp Investigators and RAISE study group investigators
Lancet, The, ISSN 0140-6736, 2012, Volume 379, Issue 9826, pp. 1613 - 1620
Summary Background Evidence indicates that corticosteroid therapy might be beneficial for the primary treatment of severe Kawasaki disease. We assessed whether... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | INTRAVENOUS GAMMA-GLOBULIN | ACUTE-PHASE | CORTICOSTEROID-THERAPY | PULSE THERAPY | JAPAN | INITIAL TREATMENT | RETREATMENT | METHYLPREDNISOLONE | ANEURYSM FORMATION | CHILDREN | Mucocutaneous Lymph Node Syndrome - drug therapy | Prospective Studies | Humans | Coronary Artery Disease - prevention & control | Child, Preschool | Infant | Male | Anti-Inflammatory Agents - therapeutic use | Female | Aspirin - therapeutic use | Prednisolone - therapeutic use | Drug Therapy, Combination | Immunoglobulins - therapeutic use | Coronary Vessel Anomalies - prevention & control | Complications and side effects | Kawasaki disease | Dosage and administration | Drug therapy | Coronary heart disease | Risk factors | Prednisolone | Clinical trials | Immunoglobulins | Disease | Medical treatment | Metabolic disorders | Corticoids | Aspirin | C-reactive protein | Intravenous administration | coronary artery | Thrombosis | Cholesterol | Proteins | Side effects | Hospitals | Motivation | Mucocutaneous lymph node syndrome | prevention | Neutropenia
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4. Full Text Post-prandial Remnant Lipoprotein Metabolism in Sitosterolemia
by Tada, Hayato and Nomura, Akihiro and Nohara, Atsushi and Inazu, Akihiro and Mabuchi, Hiroshi and Yamagishi, Masakazu and Kawashiri, Masa-aki
Journal of Atherosclerosis and Thrombosis, ISSN 1340-3478, 2018, Volume 25, Issue 12, pp. 1188 - 1195
Aim: We aimed to clarify post-prandial accumulation of remnant-like particles (RLP) in patients with sitosterolemia.Methods: Oral fat tolerance test cream... 
Remnant | OFTT | Sitosterolemia | Familial hypercholesterolemia | Remnant-like-particles | CHOLESTEROL | PARTICLES | SERUM | HYPERCHOLESTEROLEMIA | APOLIPOPROTEIN B-48 | DISEASE | PLANT STEROLS | PERIPHERAL VASCULAR DISEASE | Japan - epidemiology | Prognosis | Follow-Up Studies | Humans | Male | Incidence | Hypercholesterolemia - pathology | Lipid Metabolism, Inborn Errors - pathology | Lipoproteins - metabolism | Postprandial Period | Adult | Female | Phytosterols - adverse effects | Intestinal Diseases - epidemiology | Hypercholesterolemia - epidemiology | Biomarkers - metabolism | Lipid Metabolism, Inborn Errors - metabolism | Cholesterol - metabolism | Intestinal Diseases - metabolism | Triglycerides - metabolism | Adolescent | Phytosterols - metabolism | Lipid Metabolism, Inborn Errors - epidemiology | Heterozygote | Hypercholesterolemia - physiopathology | Hypercholesterolemia - metabolism | Intestinal Diseases - pathology | Original
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5. Full Text ANGPTL3 Deficiency and Protection Against Coronary Artery Disease
by Stitziel, Nathan O., MD, PhD and Khera, Amit V., MD and Wang, Xiao, PhD and Bierhals, Andrew J., MD, MPH and Vourakis, A. Christina, BA and Sperry, Alexandra E., BA and Natarajan, Pradeep, MD and Klarin, Derek, MD and Emdin, Connor A., DPhil and Zekavat, Seyedeh M., BSc and Nomura, Akihiro, MD and Erdmann, Jeanette, PhD and Schunkert, Heribert, MD and Samani, Nilesh J., MD and Kraus, William E., MD and Shah, Svati H., MD, MPH and Yu, Bing, PhD and Boerwinkle, Eric, PhD and Rader, Daniel J., MD and Gupta, Namrata, PhD and Frossard, Philippe M., PhD and Rasheed, Asif, MBBS and Danesh, John, DPhil and Lander, Eric S., PhD and Gabriel, Stacey, PhD and Saleheen, Danish, MBBS, PhD and Musunuru, Kiran, MD, PhD, MPH and Kathiresan, Sekar, MD and PROMIS Myocardial Infarction Genet and PROMIS and Myocardial Infarction Genetics Consortium Investigators
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2017, Volume 69, Issue 16, pp. 2054 - 2063
Abstract Background Familial combined hypolipidemia, a Mendelian condition characterized by substantial reductions in all 3 major lipid fractions, is caused by... 
Cardiovascular | Internal Medicine | human genetics | loss-of-function mutations | myocardial infarction | CARDIAC & CARDIOVASCULAR SYSTEMS | VARIANTS | CHOLESTEROL | ATHEROSCLEROSIS | RISK | TRIGLYCERIDES | OF-FUNCTION MUTATIONS | PLASMA-LIPIDS | GENE | ASSOCIATION | FAMILIAL COMBINED HYPOLIPIDEMIA | Myocardial Infarction - blood | Atherosclerosis - genetics | Humans | Mice, Inbred C57BL | Middle Aged | Risk Factors | Angiopoietins - deficiency | Male | Mutation, Missense | Angiopoietins - blood | Case-Control Studies | Mice, Knockout | Animals | Angiopoietin-like Proteins | Lipids - blood | Coronary Artery Disease - genetics | Adult | Female | Angiopoietins - genetics | Medical colleges | Genomics | Research institutes | Cardiology | Population genetics | Coronary heart disease | Cardiovascular agents | Analysis | Myocardial infarction | Angiography | Angiopoietin | Health risks | Coronary artery | Cardiovascular disease | Population studies | Triglycerides | Coronary artery disease | Low density lipoprotein | Cholesterol | Confidence intervals | Reduction | Computed tomography | Rodents | Arteriosclerosis | Atherosclerosis | Biomarkers | Infarction | Mutation | Health risk assessment | Heart diseases | Carrier density | loss of function mutations
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6. Full Text Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease
by Nomura, Akihiro and Won, Hong-Hee and Khera, Amit V and Takeuchi, Fumihiko and Ito, Kaoru and McCarthy, Shane and Emdin, Connor A and Klarin, Derek and Natarajan, Pradeep and Zekavat, Seyedeh M and Gupta, Namrata and Peloso, Gina M and Borecki, Ingrid B and Teslovich, Tanya M and Asselta, Rosanna and Duga, Stefano and Merlini, Piera A and Correa, Adolfo and Kessler, Thorsten and Wilson, James G and Bown, Matthew J and Hall, Alistair S and Braund, Peter S and Carey, David J and Murray, Michael F and Kirchner, H. Lester and Leader, Joseph B and Lavage, Daniel R and Manus, J. Neil and Hartze, Dustin N and Samani, Nilesh J and Schunkert, Heribert and Marrugat, Jaume and Elosua, Roberto and McPherson, Ruth and Farrall, Martin and Watkins, Hugh and Juang, Jyh-Ming J and Hsiung, Chao A and Lin, Shih-Yi and Wang, Jun-Sing and Tada, Hayato and Kawashiri, Masa-Aki and Inazu, Akihiro and Yamagishi, Masakazu and Katsuya, Tomohiro and Nakashima, Eitaro and Nakatochi, Masahiro and Yamamoto, Ken and Yokota, Mitsuhiro and Momozawa, Yukihide and Rotter, Jerome I and Lander, Eric S and Rader, Daniel J and Danesh, John and Ardissino, Diego and Gabriel, Stacey and Willer, Cristen J and Abecasis, Goncalo R and Saleheen, Danish and Kubo, Michiaki and Kato, Norihiro and Ida Chen, Yii-Der and Dewey, Frederick E and Kathiresan, Sekar and DiscovEHR Study Grp and Taichi Consortium
Circulation Research, ISSN 0009-7330, 06/2017, Volume 121, Issue 1, pp. 81 - 88
Rationale: Therapies that inhibit CETP (cholesteryl ester transfer protein) have failed to demonstrate a reduction in risk for coronary heart disease (CHD).... 
coronary disease | lipids | cholesteryl ester transfer protein | case-control studies | CETP | CARDIAC & CARDIOVASCULAR SYSTEMS | PROTECTION | POLYMORPHISM | DEFICIENCY | HDL | DENSITY-LIPOPROTEIN CHOLESTEROL | INHIBITION | METABOLISM | PERIPHERAL VASCULAR DISEASE | MUTATIONS | HEMATOLOGY | ASSOCIATION | Coronary Disease - blood | Humans | Middle Aged | Risk Factors | Male | Coronary Disease - diagnosis | Case-Control Studies | Cholesterol Ester Transfer Proteins - blood | Coronary Disease - genetics | Cholesterol Ester Transfer Proteins - genetics | Adult | Female | Aged | Genetic Variation - genetics | Nucleotide sequence | Exons | Lipids | Cardiovascular disease | Triglycerides | CETP gene | Low density lipoprotein | Coronary artery disease | Cholesterol | Cholesteryl ester transfer protein | Confidence intervals | Proteins | Health risk assessment | Heart diseases | Lipids and Cholesterol | exome sequencing | genetics | coronary heart disease | protein truncating variants | Coronary Artery Disease | human
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7. Full Text Room-temperature fabrication of transparent flexible thin-film transistors using amorphous oxide semiconductors
by Kamiya, Toshio and Hosono, Hideo and Hirano, Masahiro and Ohta, Hiromichi and Takagi, Akihiro and Nomura, Kenji
Nature, ISSN 0028-0836, 11/2004, Volume 432, Issue 7016, pp. 488 - 492
Transparent electronic devices formed on flexible substrates are expected to meet emerging technological demands where silicon-based electronics cannot provide... 
MULTIDISCIPLINARY SCIENCES | ELECTRONICS | Semiconductors | Transistors | Temperature
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8. Full Text Enhanced Formaldehyde‐Vapor Adsorption Capacity of Polymeric Amine‐Incorporated Aminosilicas
by Nomura, Akihiro and Jones, Christopher W
Chemistry – A European Journal, ISSN 0947-6539, 05/2014, Volume 20, Issue 21, pp. 6381 - 6390
Airborne formaldehyde, which is a highly problematic volatile organic compound (VOC) pollutant, is adsorbed by polymeric amine‐incorporated silicas... 
adsorption | formaldehyde | volatile organic compounds | silica | air qualification | ROOM-TEMPERATURE | COMBUSTION | MESOCELLULAR FOAM | OXIDE | MESOPOROUS MOLECULAR-SIEVE | SILICA PARTICLES | ADSORBENTS | CHEMISTRY, MULTIDISCIPLINARY | INDOOR AIR-POLLUTION | CO2 CAPTURE | EFFICIENT REMOVAL | Amines - chemistry | Adsorption | Polymers | Volatile Organic Compounds - chemistry | Silicon Dioxide - chemistry | Formaldehyde | Volatile organic compounds | Amines | Analysis | Chemical properties | Silica | Surface chemistry | Porosity | Silicon dioxide | Organic compounds | Covalent bonds
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9. Full Text Taming chlorophylls by early eukaryotes underpinned algal interactions and the diversification of the eukaryotes on the oxygenated Earth
by Kashiyama, Y and Yokoyama, A and Shiratori, T and Hess, S and Not, F and Bachy, C and Gutierrez-Rodriguez, A and Kawahara, J and Suzaki, T and Nakazawa, M and Ishikawa, T and Maruyama, M and Wang, MY and Chen, M and Gong, YC and Seto, K and Kagami, M and Hamamoto, Y and Honda, D and Umetani, T and Shihongi, A and Kayama, M and Matsuda, T and Taira, J and Yabuki, A and Tsuchiya, M and Hirakawa, Y and Kawaguchi, A and Nomura, M and Nakamura, A and Namba, N and Matsumoto, M and Tanaka, T and Yoshino, T and Higuchi, R and Yamamoto, A and Maruyama, T and Yamaguchi, A and Uzuka, A and Miyagishima, S and Tanifuji, G and Kawachi, M and Kinoshita, Y and Tamiaki, H
ISME JOURNAL, ISSN 1751-7362, 08/2019, Volume 13, Issue 8, pp. 1899 - 1910
Extant eukaryote ecology is primarily sustained by oxygenic photosynthesis, in which chlorophylls play essential roles. The exceptional photosensitivity of... 
ECOLOGY | MICROBIOLOGY | NOV | OCEAN | ENOL | RISE | Photosensitivity | Chlorophyll | Reactive oxygen species | Algae | Radiation | Cytotoxicity | Phylogeny | Energy harvesting | Accumulation | Eukaryotes | Chloroplasts | Solar energy | Phototoxicity | Evolution | Catabolism | Photosynthesis | Oxygenation | Dismantling
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