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Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 69, pp. 9647 - 9650
Herein we report a new class of G-quadruplex stabilising ligands, multicarbazoles, which display high G-quadruplex DNA selectivity in the presence of 250 times... 
TELOMERE TARGETING AGENTS | DNA STRUCTURES | CANCER-CELLS | DESIGN | LIGANDS | RECOGNITION | STABILIZATION | CHAINS | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | Ligands | Selectivity | Piperidine | Deoxyribonucleic acid--DNA
Journal Article
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1767, pp. 241 - 254
The potential impact of CRISPR/Cas9, TALE, and zinc finger technology is immense, both with respect to their use as tools for understanding the roles and... 
Plasmid | CRISPR | TALE | Dendrimer | Co-transfection | Zinc finger | Polymer | Gene technology | Non-viral | Cell Line | Animals | Transfection - methods | Humans | CRISPR-Cas Systems | Halogenation | Click Chemistry - methods | Dendrimers - chemistry | Dendrimers - chemical synthesis | Azides - chemical synthesis | Azides - chemistry | Transfection - economics | Index Medicus
Journal Article
ISSN 1359-7345, 8/2018, Volume 54, Issue 69, pp. 9647 - 965
Herein we report a new class of G-quadruplex stabilising ligands, multicarbazoles, which display high G-quadruplex DNA selectivity in the presence of 250 times... 
Journal Article
ISSN 2041-6520, 8/2019, Volume 1, Issue 33, pp. 7718 - 7727
Aberrant gene expression is a hallmark of cancer. Although transcription is traditionally considered 'undruggable', the development of CRISPR-associated... 
Journal Article
Chemical Science, ISSN 2041-6520, 01/2019, Volume 10, Issue 33, pp. 7718 - 7727
Aberrant gene expression is a hallmark of cancer. Although transcription is traditionally considered ‘undruggable’, the development of CRISPR-associated... 
Connective tissues | CRISPR | Toxicity | Abnormalities | Genes | Biocompatibility | Activation | Gene expression | Growth factors | Cancer | Tumors
Journal Article
Langmuir, ISSN 0743-7463, 11/2017, Volume 33, Issue 45, pp. 12926 - 12933
The composition of the protein corona formed on poly(ethylene glycol)-functionalized (PEGylated) poly(glycidyl methacrylate) (PGMA) nanoparticles (NPs) was... 
CANCER-CELLS | FE3O4 NANOPARTICLES | DRUG-DELIVERY | MATERIALS SCIENCE, MULTIDISCIPLINARY | NANOCARRIERS | CHEMISTRY, PHYSICAL | ADSORPTION | CHEMISTRY, MULTIDISCIPLINARY | CELLULAR UPTAKE | IMPACT | POLY(ETHYLENE GLYCOL) | NANOBIO INTERFACE | SURFACE | Nanoparticles | Protein Corona | Polyethylene Glycols | Polymers | Blood Proteins | Index Medicus
Journal Article
Chemical Science, ISSN 2041-6520, 2017, Volume 8, Issue 4, pp. 2923 - 2930
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic... 
POLYMERS | CELLS | GENE DELIVERY | TRANSFECTION | MASPIN | PAMAM DENDRIMERS | IN-VIVO | CLICK-CHEMISTRY | BIOMEDICAL APPLICATIONS | EFFICIENCY | CHEMISTRY, MULTIDISCIPLINARY | Platforms | Synthesis (chemistry) | Efficiency | Editing | Packaging | Strategy | Genomes | Polymers
Journal Article
ACS Symposium Series, ISSN 0097-6156, 2019, Volume 1309, pp. 1 - 34
Conference Proceeding
RSC ADVANCES, ISSN 2046-2069, 07/2019, Volume 9, Issue 35, pp. 20053 - 20057
Advances in the field of genome engineering demand the development of efficient non-viral transfection agents capable of delivering multiple distinct nucleic... 
POLYMERS | CELLS | TRANSFECTION | DNA | NANOCRYSTALS | POLYPLEX | EFFICIENCY | EXPRESSION | CHEMISTRY, MULTIDISCIPLINARY | DELIVERY
Journal Article
Organic Letters, ISSN 1523-7060, 11/2015, Volume 17, Issue 22, pp. 5517 - 5519
The tetracarbocyclic framework of the nicandrenone natural products is formed in one step from a linear precursor via a domino intramolecular... 
CYCLOADDITION | STEROIDS | FURANS | X-RAY-ANALYSIS | PHYSALOIDES | CONSTRUCTION | SYNTHETIC APPLICATIONS | CHEMISTRY | CHEMISTRY, ORGANIC | NIC-10 | DERIVATIVES | Biological Products - chemistry | Molecular Structure | Furans - chemistry | Withanolides - chemistry | Index Medicus
Journal Article
ISSN 2041-6520, 3/2017, Volume 8, Issue 4, pp. 2923 - 293
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic... 
Journal Article
Chemical Science, ISSN 2041-6520, 4/2017, Volume 8, Issue 4, pp. 2923 - 2930
Tools for editing the genome and epigenome have revolutionised the field of molecular biology and represent a new frontier in targeted therapeutic... 
Chemistry
Journal Article
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