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1. Full Text Going deeper than microscopy: the optical imaging frontier in biology
by Ntziachristos, Vasilis
Nature Methods, ISSN 1548-7091, 08/2010, Volume 7, Issue 8, pp. 603 - 614
Optical microscopy has been a fundamental tool of biological discovery for more than three centuries, but its in vivo tissue imaging ability has been... 
OPTOACOUSTIC TOMOGRAPHY | PLANE ILLUMINATION MICROSCOPY | RAMAN SCATTERING MICROSCOPY | HIGH-RESOLUTION | BIOCHEMICAL RESEARCH METHODS | IN-VIVO DETECTION | MULTIPHOTON MICROSCOPY | PHOTOACOUSTIC MICROSCOPY | 2-PHOTON MICROSCOPY | PROJECTION TOMOGRAPHY | COHERENCE TOMOGRAPHY | Microscopy - methods | Microscopy, Confocal | Tomography - methods | Microscopy - instrumentation | Microscopy, Fluorescence, Multiphoton | Optics and Photonics | Microscopy - trends | Diagnostic imaging | Microscope and microscopy | Analysis | Methods | Optics | Scientific imaging | Biology | Acoustics | Research methodology
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2. Full Text Molecular Imaging by Means of Multispectral Optoacoustic Tomography (MSOT)
by Ntziachristos, Vasilis and Razansky, Daniel
Chemical Reviews, ISSN 0009-2665, 05/2010, Volume 110, Issue 5, pp. 2783 - 2794
DEEP | SENTINEL LYMPH-NODE | FLUORESCENCE | RECONSTRUCTION | HIGH-RESOLUTION | SENSITIVITY | PHOTOACOUSTIC MICROSCOPY | PROTEINS | CHEMISTRY, MULTIDISCIPLINARY | CARBON NANOTUBES | QUANTUM DOTS | Molecular Imaging - methods | Optical Phenomena | Animals | Tomography - methods | Humans | Biomarkers - analysis | Acoustooptical devices | Infrared spectroscopy | Usage | Resolution (Optics) | Molecular structure | Analysis | Innovations | Tomography
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3. Full Text Advances in real-time multispectral optoacoustic imaging and its applications
by Taruttis, Adrian and Ntziachristos, Vasilis
Nature Photonics, ISSN 1749-4885, 03/2015, Volume 9, Issue 4, pp. 219 - 227
Optoacoustic imaging, or photoacoustic imaging, is insensitive to photon scattering within biological tissue and, unlike conventional optical imaging methods,... 
PHYSICS, APPLIED | DEEP | SENTINEL LYMPH-NODES | ULTRASOUND | VASCULATURE | PHOTOACOUSTIC TOMOGRAPHY | HIGH-RESOLUTION | MODEL | OPTICS | MICROSCOPY | CANCER | BRAIN | Lasers | Imaging | Strategy | Photons | Spectra | Biological | Differentiation | Three dimensional
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4. Opto-Acoustic Methods and Applications in Biophotonics II
by Ntziachristos, Vasilis
2015, ISBN 9781628417043
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5. Full Text Volumetric real-time multispectral optoacoustic tomography of biomarkers
by Razansky, Daniel and Buehler, Andreas and Ntziachristos, Vasilis
Nature Protocols, ISSN 1754-2189, 08/2011, Volume 6, Issue 8, pp. 1121 - 1129
Multispectral optoacoustic tomography (MSOT) has recently been developed to enable visualization of optical contrast and tissue biomarkers, with resolution and... 
SYSTEM | PHOTOACOUSTIC MICROSCOPY | RESOLUTION | ALGORITHM | BIOCHEMICAL RESEARCH METHODS | Algorithms | Animals | Tomography - methods | Image Processing, Computer-Assisted | Mice, Nude | Tomography - instrumentation | Biomarkers | Whole Body Imaging - instrumentation | Mice | Whole Body Imaging - methods | Contrast Media - analysis | Tomography | Physiological aspects | Usage | Research | Biological markers | Wavelengths | Image processing | Materials handling | Animal tissues | Chromophores | Calibration | Ultrasound | Image reconstruction | Real time operation
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6. Full Text Shedding light onto live molecular targets
by Ntziachristos, Vasilis and Weissleder, Ralph
Nature Medicine, ISSN 1078-8956, 01/2003, Volume 9, Issue 1, pp. 123 - 128
Optical sensing of specific molecular targets and pathways deep inside living mice has become possible as a result of a number of advances. These include... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | Diagnostic Imaging | Animals | Tomography - methods | Infrared Rays | Humans | Light | Fluorescence | Fluorescent Dyes - metabolism | Mice | Neoplasms - diagnosis | Luminescent Measurements | Luminescent Proteins - metabolism
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7. Full Text Revolutionizing biomedical optical imaging with multispectral optoacoustic tomography (MSOT)
by Ntziachristos, Vasilis
Toxicology Letters, ISSN 0378-4274, 08/2013, Volume 221, pp. S51 - S51
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8. Full Text Fast Semi-Analytical Model-Based Acoustic Inversion for Quantitative Optoacoustic Tomography
by Rosenthal, Amir and Razansky, Daniel and Ntziachristos, Vasilis
IEEE Transactions on Medical Imaging, ISSN 0278-0062, 06/2010, Volume 29, Issue 6, pp. 1275 - 1285
We present a fast model-based inversion algorithm for quantitative 2-D and 3-D optoacoustic tomography. The algorithm is based on an accurate and efficient... 
Optical filters | Stability | Image reconstruction | photoacoustics | Optical propagation | Optical attenuators | Imaging | Detectors | inverse problems | Tomography | Numerical simulation | Imaging phantoms | Frequency response | optoacoustics | Inverse problems | Optoacoustics | Photoacoustics | ENGINEERING, BIOMEDICAL | RECONSTRUCTION | ALGORITHM | IMAGING SCIENCE & PHOTOGRAPHIC TECHNOLOGY | ENGINEERING, ELECTRICAL & ELECTRONIC | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | tomography | PHOTOACOUSTIC TOMOGRAPHY | IN-VIVO | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | BRAIN | Elasticity Imaging Techniques - methods | Reproducibility of Results | Algorithms | Models, Biological | Computer Simulation | Image Interpretation, Computer-Assisted - methods | Sensitivity and Specificity | Imaging, Three-Dimensional - methods | Image Enhancement - methods | Photoacoustic spectroscopy | Image processing | Analysis | Studies
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9. Advancing Surgical Vision with Fluorescence Imaging
by Maximilian Koch and Vasilis Ntziachristos
Annual Review of Medicine, ISSN 0066-4219, 01/2016, Volume 67, p. 153
  Surgical success depends on the accuracy with which disease and vital tissue can be intraoperatively detected. However, the dominant visualization approach,... 
Tissue | Accuracy | Decision making | Surgery | Fluorescence
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10. Opto-Acoustic Methods and Applications in Biophotonics II
by Ntziachristos, Vasilis and Zemp, Roger
2015
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11. Full Text Compression of Born ratio for fluorescence molecula tomography/x-ray computed tomography hybrid imaging: Methodology and in vivo validation
by Mohajerani, Pouyan and Ntziachristos, Vasilis
Optics Letters, ISSN 0146-9592, 07/2013, Volume 38, Issue 13, pp. 2324 - 2326
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12. Full Text Clinical translation of optical and optoacoustic imaging
by Vasilis Ntziachristos
Philosophical Transactions: Mathematical, Physical and Engineering Sciences, ISSN 1364-503X, 11/2011, Volume 369, Issue 1955, pp. 4666 - 4678
Macroscopic optical imaging has rather humble technical origins; it has been mostly implemented by photographic means using appropriate filters, a light source... 
Photography | Molecular imaging | Wavelengths | Colors | Imaging | Optical properties | Ultrasonography | Images | Fluorescence | Diagnostic imaging | Optoacoustic | Clinical | Intravascular | Multi-spectral | Near-infrared | TOMOGRAPHY | SYSTEM | INFRARED FLUORESCENCE CATHETER | intravascular | RESECTION | MULTIDISCIPLINARY SCIENCES | RATIO | optoacoustic | MICROSCOPY | imaging | clinical | near-infrared | multi-spectral | IN-VIVO | REAL-TIME | Biomarkers - metabolism | Catheterization | Kidney - pathology | Humans | Uterine Cervical Neoplasms - surgery | Uterine Cervical Neoplasms - pathology | Acoustics | Spectroscopy, Near-Infrared - methods | Diagnostic Imaging - methods | Vision, Ocular - physiology | Animals | Microscopy, Fluorescence - methods | Abdomen - pathology | Optics and Photonics - methods | Female | Perception | Mice | Scattering, Radiation | Translational Medical Research - methods | Photography - methods
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13. Full Text Spectral unmixing techniques for optoacoustic imaging of tissue pathophysiology
by Tzoumas, Stratis and Ntziachristos, Vasilis
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, ISSN 1364-503X, 11/2017, Volume 375, Issue 2107, p. 20170262
A key feature of optoacoustic imaging is the ability to illuminate tissue at multiple wavelengths and therefore record images with a spectral dimension. While... 
Spectroscopic photoacoustic imaging | Multispectral optoacoustic imaging | Spectral unmixing | TOMOGRAPHY | spectral unmixing | DEEP | spectroscopic photoacoustic imaging | MULTIDISCIPLINARY SCIENCES | multispectral optoacoustic imaging | INVERSION | 125 | 1002 | Review | 196
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14. Full Text Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: Perspectives on tracking and neuroimaging
by Bhaskar, Sonu and Tian, Furong and Stoeger, Tobias and Kreyling, Wolfgang and de la Fuente, Jesús M and Grazú, Valeria and Borm, Paul and Estrada, Giovani and Ntziachristos, Vasilis and Razansky, Daniel
Particle and Fibre Toxicology, ISSN 1743-8977, 03/2010, Volume 7, Issue 1, pp. 3 - 3
Nanotechnology has brought a variety of new possibilities into biological discovery and clinical practice. In particular, nano-scaled carriers have... 
MULTISPECTRAL OPTOACOUSTIC TOMOGRAPHY | SOLID LIPID NANOPARTICLES | POLY(BUTYL CYANOACRYLATE) NANOPARTICLES | RECEPTOR-MEDIATED ENDOCYTOSIS | IN-VIVO | CENTRAL-NERVOUS-SYSTEM | CONJUGATED PEGYLATED NANOPARTICLES | TOXICOLOGY | FLUORESCENCE MOLECULAR TOMOGRAPHY | MAGNETIC NANOPARTICLES | WALLED CARBON NANOTUBES | Central Nervous System Agents - therapeutic use | Humans | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Drug Carriers | Brain - drug effects | Magnetic Resonance Imaging | Animals | Image Processing, Computer-Assisted | Nanoparticles - therapeutic use | Nanomedicine - methods | Brain - pathology | Drug Delivery Systems - methods | Neuroimaging | Drugs | Technology application | Drug delivery systems | Blood-brain barrier | Design and construction | Research | Properties | Methods | Nanotechnology | Pharmaceutical biotechnology | Vehicles | Medical imaging | Disease | Tissue engineering | Manuscripts | Molecular weight | Nanoparticles | Tomography | Life sciences | Clinical medicine | Pharmaceutical industry | Gene therapy | Tumors
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15. Optoacoustic Imaging of Naphthalocyanine: Potential for Contrast Enhancement and Therapy Monitoring
by Beziere, Nicolas and Ntziachristos, Vasilis
Journal of Nuclear Medicine, ISSN 0161-5505, 02/2015, Volume 56, Issue 2, pp. 323 - 323
We investigated in vitro and in vivo the optoacoustic responses of silicon 2,3-naphthalocyanine bi(trihexylsilyloxide) (SiNc), considered herein as a reporter... 
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16. Optoacoustic Imaging of Naphthalocyanine: Potential for Contrast Enhancement and Therapy Monitoring
by Nicolas Bézière and Vasilis Ntziachristos
The Journal of Nuclear Medicine, ISSN 0161-5505, 02/2015, Volume 56, Issue 2, p. 323
  We investigated in vitro and in vivo the optoacoustic responses of silicon 2,3-naphthalocyanine bi(trihexylsilyloxide) (SiNc), considered herein as a... 
Nuclear medicine | Molecules | Rodents | Silicon | Tumors
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17. Full Text Two-Dimensional Intravascular Near-Infrared Fluorescence Molecular Imaging of Inflammation in Atherosclerosis and Stent-Induced Vascular Injury
by Jaffer, Farouc A., MD, PhD and Calfon, Marcella A., MD, PhD and Rosenthal, Amir, PhD and Mallas, Georgios, MSc and Razansky, R. Nika, PhD and Mauskapf, Adam, BS and Weissleder, Ralph, MD, PhD and Libby, Peter, MD and Ntziachristos, Vasilis, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 57, Issue 25, pp. 2516 - 2526
Objectives This study sought to develop a 2-dimensional (2D) intravascular near-infrared fluorescence (NIRF) imaging strategy for investigation of arterial... 
Cardiovascular | Internal Medicine | atherosclerosis | stent | intravascular imaging | molecular imaging | inflammation | SYSTEM | DESIGN | CARDIAC & CARDIOVASCULAR SYSTEMS | THROMBOSIS | DRUG-ELUTING STENT | IN-VIVO | CARDIOVASCULAR-DISEASE | CYSTEINE PROTEASES | Catheterization, Peripheral - instrumentation | Rabbits | Animals | Coronary Artery Disease - diagnosis | Inflammation - diagnosis | Spectroscopy, Near-Infrared - methods | Spectroscopy, Near-Infrared - instrumentation | Stents | Fluorescent Dyes | Medical colleges | Atherosclerosis | Fluorescence | Inflammation | Cardiology | Stent (Surgery) | Medical imaging equipment | Medical imaging | Catheters | Veins & arteries
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18. Full Text Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging
by Ntziachristos, Vasilis and Bremer, Christoph and Weissleder, Ralph
European Radiology, ISSN 0938-7994, 1/2003, Volume 13, Issue 1, pp. 195 - 208
A recent development in biomedical imaging is the non-invasive mapping of molecular events in intact tissues using fluorescence. Underpinning to this... 
Near infrared In vivo Molecular imaging Fluorescence | Molecular imaging | Fluorescence | In vivo | Near infrared | near infrared | HUMAN SKIN | CONTRAST AGENTS | TURBID MEDIA | molecular imaging | MICROSCOPY | TUMORS | BREAST-CANCER | RESOLVED OPTICAL TOMOGRAPHY | fluorescence | IN-VIVO | MAGNETIC-RESONANCE | in vivo | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | CATHEPSIN-B | Diagnostic Imaging | Animals | Spectroscopy, Near-Infrared | Infrared Rays | Humans | Tomography | Mice | Fluorescent Dyes
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