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1. Full Text Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
by Trynka, G and Hunt, K.A and Bockett, N.A and Romanos, J and Mistry, V and Szperl, A and Bakker, S.F and Bardella, M.T and Bhaw-Rosun, L and Castillejo, G and Concha, E. de la and Almeida, R.C. de and Dias, K.R and Diemen, C.C. van and Dubois, P.C and Duerr, R.H and Edkins, S and Franke, L and Fransen, K and Gutierrez, J and Heap, G.A and Hrdlickova, B and Hunt, S and Izurieta, L.P and Izzo, V and Joosten, L.A.B and Langford, C and Mazzilli, M.C and Mein, C.A and Midah, V and Mitrovic, M and Mora, B and Morelli, M and Nutland, S and Nunez, C and Onengut-Gumuscu, S and Pearce, K and Platteel, M and Polanco, I and Potter, S and Ribes-Koninckx, C and Ricano-Ponce, I and Rich, S.S and Rybak, A and Santiago, J.L and Senapati, S and Sood, A and Szajewska, H and Troncone, R and Varade, J and Wallace, C and Wolters, V.M and Zhernakova, A and Thelma, B.K and Cukrowska, B and Urcelay, E and Bilbao, J.R and Mearin, ML and Barisani, D and Barrett, J.C and Plagnol, V and Deloukas, P and Wijmenga, C and Heel, D.A. van and Spanish Consortium Genetics Coelia and WTCCC and PreventCD Study Grp and Spanish Consortium on the Genetics of Coeliac Disease (CEGEC) and Wellcome Trust Case Control Consortium (WTCCC) and PreventCD Study Group
Nature genetics, ISSN 1061-4036, 2011, Volume 43, Issue 12, pp. 1193 - 1201
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Gastroenterology. Liver. Pancreas. Abdomen | Stomach. Duodenum. Small intestine. Colon. Rectum. Anus | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Other diseases. Semiology | Haplotypes | Genome-Wide Association Study | Celiac Disease - genetics | Gene Frequency | Humans | Risk Factors | Chromosome Mapping | Polymorphism, Single Nucleotide | Genetic Loci | Case-Control Studies | Linkage Disequilibrium | Celiac disease | Genetic aspects | Single nucleotide polymorphisms | Research | Risk factors | Medical research | Disease | Health services | Thyroid diseases | Genomes | Grants | Genotype & phenotype | Diet | Quality control | Diabetes | Genetic testing | Deoxyribonucleic acid--DNA | Index Medicus
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2. Full Text High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
by Eyre, Steve and Bowes, John and Diogo, Dorothee and Lee, Annette and Barton, Anne and Martin, Paul and Zhernakova, Alexana and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and Amos, Christopher I and Padyukov, Leonid and Toes, Rene E. M and Huizinga, Tom W. J and Wijmenga, Cisca and Trynka, Gosia and Franke, Lude and Westra, Harm-Jan and Alfredsson, Lars and Hu, Xinli and Sandor, Cynthia and de Bakker, Paul I. W and Davila, Sonia and Khor, Chiea Chuen and Heng, Khai Koon and Anews, Robert and Edkins, Sarah and Hunt, Sarah E and Langford, Cordelia and Symmons, Deborah and Concannon, Pat and Onengut-Gumuscu, Suna and Rich, Stephen S and Deloukas, Panos and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Arlsetig, Lisbeth and Martin, Javier and Rantapaa-Dahlqvist, Solbritt and Plenge, Robert M and Raychaudhuri, Soumya and Klareskog, Lars and Gregersen, Peter K and Worthington, Jane and Biol Rheumatoid Arthrit Genetics G and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate
Nature genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1336 - 1340
INTERLEUKIN-6 RECEPTOR | RISK LOCI | METAANALYSIS | CORONARY-HEART-DISEASE | EXPRESSION | ASSOCIATION | UMCG Approved | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Diseases of the osteoarticular system | Inflammatory joint diseases | Biological and medical sciences | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Methods, theories and miscellaneous | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Oligonucleotide Array Sequence Analysis | Autoantibodies - blood | Humans | Male | Genetic Loci | Chromosome Mapping - instrumentation | Arthritis, Rheumatoid - genetics | Chromosome Mapping - methods | Female | Polymorphism, Single Nucleotide | Autoantibodies - genetics | Rheumatoid arthritis | Physiological aspects | Genetic aspects | Disease susceptibility | Single nucleotide polymorphisms | Research | Chromosomes | Studies | Medical research | Autoimmune diseases | Index Medicus | Medicin och hälsovetenskap
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3. Full Text Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A
by Nejentsev, Sergey and Bailey, Rebecca and Hardy, Matthew and Cooper, Jason D and Howson, Joanna M. M and Walker, Neil M and Maier, Lisa M and Ribas, Gloria and King, Erna and Szeszko, Jeffrey and Field, Sarah F and Reynolds, Pamela and Smyth, Deborah and Todd, John A and Hulme, John and Clayton, David G and Masters, Jennifer and Stevens, Helen E and Campbell, R. Duncan and Wellcome Trust Case Control Consor and Wellcome Trust Case Control Consortium and The Wellcome Trust Case Control Consortium
Nature (London), ISSN 0028-0836, 12/2007, Volume 450, Issue 7171, pp. 887 - 92
Diabetes Mellitus, Type 1/genetics | European Continental Ancestry Group/genetics | HLA-B Antigens/genetics | Gene Frequency | Humans | Databases, Genetic | HLA-DR Antigens/genetics | Genetic Predisposition to Disease/genetics | Genotype | Case-Control Studies | Genes, MHC Class II/genetics | Polymorphism, Single Nucleotide/genetics | Sample Size | HLA-DRB1 Chains | Alleles | Genes, MHC Class I/genetics | HLA-A Antigens/genetics | HLA-DQ Antigens/genetics | HLA-DQ beta-Chains | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genes, MHC Class I - genetics | Diabetes Mellitus, Type 1 - genetics | HLA-DR Antigens - genetics | Genes, MHC Class II - genetics | HLA-DQ Antigens - genetics | HLA-A Antigens - genetics | Polymorphism, Single Nucleotide - genetics | HLA-B Antigens - genetics | Genotype & phenotype | Statistical analysis | Genomics | Diabetes | Autoimmune diseases | Gene expression | Chromosomes | Index Medicus
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4. Full Text Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
by Onengut-Gumuscu, Suna and Chen, Wei-Min and Burren, Oliver and Cooper, Nick J and Quinlan, Aaron R and Mychaleckyj, Josyf C and Farber, Emily and Bonnie, Jessica K and Szpak, Michal and Schofield, Ellen and Achuthan, Premanand and Guo, Hui and Fortune, Mary D and Stevens, Helen and Walker, Neil M and Ward, Lucas D and Kundaje, Anshul and Kellis, Manolis and Daly, Mark J and Barrett, Jeffrey C and Cooper, Jason D and Deloukas, Panos and Todd, John A and Wallace, Chris and Concannon, Patrick and Rich, Stephen S and Baskerville, Tracey and Bautista, Nines and Bhatia, Eesh and Bhatia, Vijayalakshmi and Hasan, Kamaruzaman Bin and Bonnici, Francois and Brodnicki, Thomas and Browning, Brian and Cameron, Fergus and Chaichanwatanakul, Katharee and Cheung, Pik To and Colman, Peter and Cotterill, Andrew and Couper, Jenny and Crock, Patricia and Cutfield, Ric and Davis, Tim and Dixon, Paul and Donaghue, Kim and Dowling, Katrina and Drury, Paul and Dye, Sarah and Gellert, Shane and Ghani, Rohana Abdul and Greer, Ristan and Han, Xueyao and Harrison, Len and Homatopoulos, Nick and Ji, Linong and Jones, Tim and Yin, Loke Kah and Kamaruddin, Nor Azmi and Kanga, Uma and Kanungo, Alok and Kaur, Gurvinder and Kek, Betty and Knowles, Simon and Krebs, Jeremy and Kumar, Neeraj and Lee, Yann-Jinn and Li, Xiaoying and Liktimaskul, Supawadee and Lloyd, Margaret and Loth, Amanda and Louey, Anthony and Mehra, Narinder and Merriman, Tony and Min, Liu and Morahan, Grant and Moses, Robert and Mraz, Grant and Murphy, Rinki and Nicholson, Ian and Panelo, Araceli and Poh, Perlita and Price, Gareth and Ratnam, Nirubasini and Sanjeevi, Carani and Sedimbi, Saikiran and Shen, Shuixian and Ying, Goh Siok and Tait, Brian and Tandon, Nikhil and Thomas, Allison and Varney, Mike and Weerakulwattana, Praewvarin and Willis, Jinny and Akwo, Elvis Abang and Albret, Lotte and Ampudia-Blasco, Francisco and Argente, Jesus and Avbelj, Magdalena and Babadjanova, Gulja and Badenhoop, Klaus and ... and Type 1 Diabet Genetics Consortium and Type 1 Diabetes Genetics Consortium
Nature genetics, ISSN 1061-4036, 04/2015, Volume 47, Issue 4, pp. 381 - 386
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Quantitative trait loci | Genetic aspects | Disease susceptibility | Type 1 diabetes | Identification and classification | Risk factors | Studies | Inflammatory bowel disease | Biomedical research | Disease | Laboratories | Genomics | Rheumatoid arthritis | Quality control | Genomes | Genetic testing | Diabetes | Deoxyribonucleic acid--DNA | Index Medicus | Medicin och hälsovetenskap
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5. Full Text Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
by Wallace, Chris and Lam, Alex A C and Field, Sarah F and Plagnol, Vincent and Howson, Joanna M M and Leung, Hin-Tak and Nejentsev, Sergey and Smink, Luc J and Adlem, Ellen and Todd, John A and Downes, Kate and Vella, Adrian and Heward, Joanne M and Bailey, Rebecca and Szeszko, Jeffrey S and Yang, Jennie H M and Meadows, William and Smyth, Deborah J and Payne, Felicity and Lowe, Christopher E and Hafler, Jason P and Maisuria, Meeta and Gough, Stephen C L and Wicker, Linda S and Ovington, Nigel R and Stevens, Helen E and Walker, Neil M and Burren, Oliver S and Allen, James and Coleman, Gillian and Ionescu-Tîrgovi te, Constantin and Dunger, David B and Zeitels, Lauren and Nutland, Sarah and Clayton, David G and Schuilenburg, Helen and Healy, Barry and Guja, Cristian and Simmonds, Matthew J and Cooper, Jason D and Wellcome Trust Case Control Consor and Genetics Type 1 Diabet Finland and Wellcome Trust Case Control Consortium and Genetics of Type 1 Diabetes in Finland and the Wellcome Trust Case Control Consortium
Nature genetics, ISSN 1061-4036, 07/2007, Volume 39, Issue 7, pp. 857 - 64
Diabetes Mellitus, Type 1/genetics | Genetic Predisposition to Disease | Humans | Adolescent | Chromosome Mapping | Polymorphism, Single Nucleotide | Genome, Human | Case-Control Studies | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | Diabetes. Impaired glucose tolerance | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Diabetes Mellitus, Type 1 - genetics | Quantitative trait loci | Type 1 diabetes | Physiological aspects | Genetic aspects | Research | Single nucleotide polymorphisms | Diagnosis | Identification and classification | Diabetes | Autoimmune diseases | Chromosomes | Genomics | Thyroid diseases | Index Medicus
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6. Full Text An analysis of baseline data from the PROUD study: An open-label randomised trial of pre-exposure prophylaxis
by Dolling, David I and Desai, Monica and McOwan, Alan and Gilson, Richard and Clarke, Amanda and Fisher, Martin and Schembri, Gabriel and Sullivan, Ann K and Mackie, Nicola and Reeves, Iain and Portman, Mags and Saunders, John and Fox, Julie and Bayley, Jake and Brady, Michael and Bowman, Christine and Lacey, Charles J and Taylor, Stephen and White, David and Antonucci, Simone and Gafos, Mitzy and McCormack, Sheena and Gill, Owen N and Dunn, David T and Nardone, Anthony and Apea, Vanessa and Clark, Drew and Davis, Paul and Hand, James and Hunt, Machel and Neale, Rebecca and O'Connell, Jackie and Portman, Margaret and Sarner, Liat and Terry, Louise and Twumasi, Angelina and Tsui, Salina and Vijeratnam, Dayan and Whyte, Ryan and Williams, Andy and Gately, Sian and Gilleran, Gerry and Lyons, Jill and McCormack, Chris and Moore, Katy and Stretton, Cathy and White, David and Acheampong, Alex and Bramley, Michael and Campbell, Marion and Chowdhry, Ruby and Eastwood, Stewart and Fennell, Babs and Hadley, Wendy and Hobbs, Kerry and Kirk, Sarah and Perry, Nicky and Rawlinson, Charlotte and Richardson, Celia and Richardson, Claire and Roche, Mark and Simpkin, Emma and Shaw, Simon and Souto, Elisa and Williams, Julia and Youssef, Elaney and Barber, Tristan and Eliot, Cindy and Fedele, Serge and Higgs, Chris and McCormick, Kathryn and Meijer, Alexandra and Pepper, Sam and Rowlands, Jane and Singh, Gurmit and Soler-Carracedo, Alfredo and Sonecha, Sonali and Sullivan, Ann and Taylor, David and Thomas, Lervina and Clarke, Rich and Rooney, Jim and Attakora, Frederick and Bourke, Marina and Castles, Richard and Clark, Rebecca and De-Masi, Anke and Espa, Veronica and Hungwe, Rumbidzai and Lincoln, Martin and Mguni, Sifiso and Nevin-Dolan, Rhianon and Alexander, Hannah and Campbell, Lucy and Candfield, Sophie and Doshi, Shema and Liddle, Olivia and Mulka, Larissa and Saigal, Priyanka and Stevenson, James and ... and PROUD Study Grp and PROUD Study Group and On behalf of the PROUD Study Group
Trials, ISSN 1745-6215, 03/2016, Volume 17, Issue 1, pp. 163 - 163
Tenofovir | Pre-exposure prophylaxis (PrEP) | Men who have sex with men (MSM) | HIV prevention | Truvada | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | HIV Infections - prevention & control | HIV Infections - epidemiology | Humans | Middle Aged | Male | Reverse Transcriptase Inhibitors - administration & dosage | Unsafe Sex - prevention & control | Socioeconomic Factors | Incidence | Anti-HIV Agents - administration & dosage | Reverse Transcriptase Inhibitors - adverse effects | Young Adult | Homosexuality, Male | Time Factors | England - epidemiology | Adult | HIV Infections - transmission | Surveys and Questionnaires | Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination - adverse effects | Drug Administration Schedule | Risk Assessment | Anti-HIV Agents - adverse effects | HIV Infections - virology | Risk Factors | Treatment Outcome | Pilot Projects | Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination - administration & dosage | Adolescent | Primary Prevention - methods | Care and treatment | HIV (Viruses) | MSM (Men who have sex with men) | Health aspects | Index Medicus
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7. Full Text Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
by Burton, Paul R and Clayton, David G and Cardon, Lon R and Craddock, Nick and Deloukas, Panos and Duncanson, Audrey and Kwiatkowski, Dominic P and McCarthy, Mark I and Ouwehand, Willem H and Samani, Nilesh J and Todd, John A and Donnelly, Peter and Barrett, Jeffrey C and Davison, Dan and Easton, Doug and Evans, David M and Leung, Hin-Tak and Marchini, Jonathan L and Morris, Andrew P and Spencer, Chris C.A and Tobin, Martin D and Attwood, Antony P and Boorman, James P and Cant, Barbara and Everson, Ursula and Hussey, Judith M and Jolley, Jennifer D and Knight, Alexandra S and Koch, Kerstin and Meech, Elizabeth and Nutland, Sarah and Prowse, Christopher V and Stevens, Helen E and Taylor, Niall C and Walters, Graham R and Walker, Neil M and Watkins, Nicholas A and Winzer, Thilo and Jones, Richard W and McArdle, Wendy L and Ring, Susan M and Strachan, David P and Pembrey, Marcus and Breen, Gerome and Clair, David St and Caesar, Sian and Gordon-Smith, Katharine and Jones, Lisa and Fraser, Christine and Green, Elaine K and Grozeva, Detelina and Hamshere, Marian L and Holmans, Peter A and Jones, Ian R and Kirov, George and Moskivina, Valentina and Nikolov, Ivan and O'Donovan, Michael C and Owen, Michael J and Collier, David A and Elkin, Amanda and Farmer, Anne and Williamson, Richard and McGuffin, Peter and Young, Allan H and Ferrier, I. Nicol and Ball, Stephen G and Balmforth, Anthony J and Barrett, Jennifer H and Bishop, Timothy D and Iles, Mark M and Maqbool, Azhar and Yuldasheva, Nadira and Hall, Alistair S and Braund, Peter S and Dixon, Richard J and Mangino, Massimo and Stevens, Suzanne and Thompson, John R and Bredin, Francesca and Tremelling, Mark and Parkes, Miles and Drummond, Hazel and Lees, Charles W and Nimmo, Elaine R and Satsangi, Jack and Fisher, Sheila A and Forbes, Alastair and Lewis, Cathryn M and Onnie, Clive M and Prescott, Natalie J and Sanderson, Jeremy and Matthew, Christopher G and Barbour, Jamie and Mohiuddin, M. Khalid and Todhunter, Catherine E and Mansfield, John C and Ahmad, Tariq and Cummings, Fraser R and Jewell, Derek P and ... and Breast Cancer Susceptibility Collaboration (UK) and Wellcome Trust Case Control Consortium and Biologics in RA Genetics and Genomics Study Syndicate (BRAGGS) Steering Committee and Australo-Anglo-American Spondylitis Consortium (TASC) and The Australo-Anglo-American Spondylitis Consortium (TASC)
Nature genetics, ISSN 1061-4036, 11/2007, Volume 39, Issue 11, pp. 1329 - 1337
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Genetics, Population | Aminopeptidases - genetics | Spondylitis, Ankylosing - genetics | Minor Histocompatibility Antigens | Thyroiditis, Autoimmune - epidemiology | Humans | Autoimmunity - genetics | Genotype | Multiple Sclerosis - genetics | Chromosome Mapping | Multiple Sclerosis - epidemiology | Receptors, Interleukin - genetics | Thyroiditis, Autoimmune - genetics | Case-Control Studies | Linkage Disequilibrium | Haplotypes - genetics | Breast Neoplasms - genetics | Polymerase Chain Reaction | Spondylitis, Ankylosing - epidemiology | Polymorphism, Single Nucleotide - genetics | North America - epidemiology | Receptors, Immunologic - genetics | Breast Neoplasms - epidemiology | Histocompatibility antigens | HLA histocompatibility antigens | Physiological aspects | Genetic aspects | Diagnosis | Research | Single nucleotide polymorphisms | Ankylosing spondylitis | Risk factors | Genotype & phenotype | Multiple sclerosis | Genetic research | Genetics | Arthritis | Breast cancer | Autoimmune diseases | Index Medicus
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