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by Sabater-Lleal, M and Huang, J and Chasman, D and Naitza, S and Dehghan, A and Johnson, AD and Teumer, A and Reiner, AP and Folkersen, L and Basu, S and Rudnicka, AR and Trompet, S and Malarstig, A and Baumert, J and Bis, JC and Guo, XQ and Hottenga, JJ and Shin, SY and Lopez, LM and Lahti, J and Tanaka, T and Yanek, LR and Oudot-Mellakh, T and Wilson, JF and Navarro, P and Huffman, JE and Zemunik, T and Redline, S and Mehra, R and Pulanic, D and Rudan, I and Wright, AF and Kolcic, I and Polasek, O and Wild, SH and Campbell, H and Curb, JD and Wallace, R and Liu, SM and Eaton, CB and Becker, DM and Becker, LC and Bandinelli, S and Raikkonen, K and Widen, E and Palotie, A and Fornage, M and Green, D and Gross, M and Davies, G and Harris, SE and Liewald, DC and Starr, JM and Williams, FMK and Grant, PJ and Spector, TD and Strawbridge, RJ and Silveira, A and Sennblad, B and Rivadeneira, F and Uitterlinden, AG and Franco, OH and Hofman, A and van Dongen, J and Willemsen, G and Boomsma, DI and Yao, J and Jenny, NS and Haritunians, T and McKnight, B and Lumley, T and Taylor, KD and Rotter, JI and Psaty, BM and Peters, A and Gieger, C and Illig, T and Grotevendt, A and Homuth, G and Volzke, H and Kocher, T and Goel, A and Franzosi, MG and Seedorf, U and Clarke, R and Steri, M and Tarasov, KV and Sanna, S and Schlessinger, D and Stott, DJ and Sattar, N and Buckley, BM and Rumley, A and Lowe, GD and McArdle, WL and Chen, MH and Tofler, GH and Song, J and Boerwinkle, E and Folsom, AR and ... and VTE Consortium and CD4 Consortium and STROKE Consortium and CARDIoGRAM Consortium and WTCCC2
CIRCULATION, ISSN 0009-7322, 09/2013, Volume 128, Issue 12, pp. 1310 - 1324
Background Estimates of the heritability of plasma fibrinogen concentration, an established predictor of cardiovascular disease, range from 34% to 50%. Genetic... 
CARDIAC & CARDIOVASCULAR SYSTEMS | RISK-FACTORS | fibrinogen | VARIANTS | genome-wide association study | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | cardiovascular diseases | CORONARY-HEART-DISEASE | HEMOSTASIS | gene expression
Journal Article
by van der Laan, Sander W and Fall, Tove and Soumaré, Aicha and Teumer, Alexander and Sedaghat, Sanaz and Baumert, Jens and Zabaneh, Delilah and van Setten, Jessica and Isgum, Ivana and Galesloot, Tessel E and Arpegård, Johannes and Amouyel, Philippe and Trompet, Stella and Waldenberger, Melanie and Dörr, Marcus and Magnusson, Patrik K and Gieaitis, Vilmantas and Larsson, Anders and Morris, Anew P and Felix, Janine F and Morrison, Alanna C and Franceschini, Nora and Bis, Joshua C and Kavousi, Maryam and O'Donnell, Christopher and nos, Fotios and Tragante, Vinicius and Munroe, Patricia B and Malik, Rainer and Dichgans, Martin and Worrall, Bradford B and Erdmann, Jeanette and Nelson, Christopher P and Samani, Nilesh J and Schunkert, Heribert and Marchini, Jonathan and Patel, Riyaz S and Hingorani, Aroon D and Lind, Lars and Pedersen, Nancy L and de Graaf, Jacqueline and Kiemeney, Lambertus A. L. M and Baumeister, Sebastian E and Franco, Oscar H and Hofman, Albert and Uitterlinden, Ané G and Koenig, Wolfgang and Meisinger, Christa and Peters, Annette and Thorand, Barbara and Jukema, J. Wouter and Eriksen, Bjørn Odvar and Toft, Ingrid and Wilsgaard, Tom and Onland-Moret, N. Charlotte and van der Schouw, Yvonne T and Debette, Stéphanie and Kumari, Meena and Svensson, Per and van der Harst, Pim and Kivimaki, Mika and Keating, Brendan J and Sattar, Naveed and Dehghan, Abbas and Reiner, Alex P and Ingelsson, Erik and den Ruijter, Hester M and de Bakker, Paul I. W and Pasterkamp, Gerard and Ärnlöv, Johan and Holmes, Michael V and Asselbergs, Folkert W and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Geriatrik and Biokemisk struktur och funktion and Kardiovaskulär epidemiologi and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi and Institutionen för folkhälso- och vårdvetenskap
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 68, Issue 9, pp. 934 - 945
Journal Article
by Bohula, Erin A and Scirica, Benjamin M and Inzucchi, Silvio E and McGuire, Darren K and Keech, Anthony C and Smith, Steven R and Kanevsky, Estella and Murphy, Sabina A and Leiter, Lawrence A and Dwyer, Jamie P and Corbalan, Ramon and Hamm, Christian and Kaplan, Lee and Nicolau, Jose Carlos and Ophuis, Ton Oude and Ray, Kausik K and Ruda, Mikhail and Spinar, Jindrich and Patel, Tushar and Miao, Wenfeng and Perdomo, Carlos and Francis, Bruce and Dhadda, Shobha and Bonaca, Marc P and Ruff, Christian T and Sabatine, Marc S and Wiviott, Stephen D and Sabatine, Marc S and Wiviott, Stephen D and Scirica, Benjamin M and Inzucchi, Silvio and Keech, Anthony and McGuire, Darren K and Smith, Steven R and Satlin, Andrew and Brown, Conville and Budaj, Andrzej and Corbalan, Ramon and Dwyer, Jamie and Garcia-Castillo, Armando and Gupta, Milan and Hamm, Christian and Kaplan, Lee and Leiter, Lawrence A and Nicolau, Jose Carlos and Oude Ophuis, Ton and Ray, Kauski and Ruda, Mikhail and Spinar, Jindrich and Weissman, Neil and White, Harvey D and Amerena, J and Arstall, M and Colquhoun, D and Jayasinghe, R and Lee, A and Lehman, R and Moses, R and Proietto, J and Purnell, P and Waites, J and Blombery, P and Cross, D and Worthley, M and d'Emden, M and Selvanayagam, J and Oqueli, RE and Whelan, A and Garrahy, P and de Looze, F and Ninio, D and Horowitz, J and William, M and Suranyi, M and Wittert, G and Le May, M and Pandey, AS and Vizel, S and Labonte, R and Beaudry, Y and Fortin, C and Bell, A and Kouz, S and St-Amour, É and Bata, I and St Maurice, F and Chehayeb, R and Constance, C and Wong, G and Hess, A and Liutkus, J and Poirier, P and Teitelbaum, I and Berlingieri, J and Cha, J and Hartleib, M and Heffernan, M and Twum-Barima, D and Pandith, V and Aronson, R and ... and CAMELLIA-TIMI 61 Steering Committee Investigators and CAMELLIA-TIMI61 Steering Comm
The Lancet, ISSN 0140-6736, 11/2018, Volume 392, Issue 10161, pp. 2269 - 2279
There is a direct relationship between bodyweight and risk of diabetes. Lorcaserin, a selective serotonin 2C receptor agonist that suppresses appetite, has... 
LIFE-STYLE INTERVENTION | MEDICINE, GENERAL & INTERNAL | THERAPY | LIRAGLUTIDE | REDUCTION | CARDIOVASCULAR OUTCOMES | WEIGHT-LOSS | BARIATRIC SURGERY | FOLLOW-UP | ASSOCIATION | Glycated Hemoglobin A - analysis | Hypoglycemic Agents - therapeutic use | Overweight - complications | Atherosclerosis - drug therapy | Double-Blind Method | Obesity - complications | Humans | Middle Aged | Diabetes Mellitus, Type 2 - prevention & control | Prediabetic State - prevention & control | Body Weight - drug effects | Atherosclerosis - complications | Male | Prediabetic State - complications | Weight Loss - drug effects | Appetite Depressants - therapeutic use | Prediabetic State - drug therapy | Remission Induction | Diabetes Mellitus, Type 2 - blood | Benzazepines - therapeutic use | Female | Aged | Diabetes Mellitus, Type 2 - drug therapy | Diabetes Mellitus, Type 2 - complications | Type 2 diabetes | Prevention | Clinical trials | Obesity | Analysis | Diabetic retinopathy | Heart attacks | Body weight | Cardiovascular disease | Diabetic neuropathy | Body weight loss | Evidence-based medicine | Risk factors | Body mass index | Randomization | Hyperglycemia | Vascular diseases | Motivation | Atherosclerosis | Hemoglobin | Remission | Diabetes mellitus (non-insulin dependent) | Appetite | Hypertension | Serotonin | Complications | Diabetes mellitus | Weight loss | Health risks | FDA approval | Hypoglycemia | Metabolism | Risk analysis | Patients | Disease control | Disease prevention | Weight control | Statistical models | Arteriosclerosis | Coronary vessels | Microvasculature | Lifestyles | Gastrointestinal surgery | Diabetes | Health risk assessment | Long-term effects
Journal Article
by Carbone, Marco and Sharp, Stephen J and Flack, Steve and Paximadas, Dimitrios and Spiess, Kelly and Adgey, Carolyn and Griffiths, Laura and Lim, Reyna and Trembling, Paul and Williamson, Kate and Wareham, Nick J and Aldersley, Mark and Bathgate, Andrew and Burroughs, Andrew K and Heneghan, Michael A and Neuberger, James M and Thorburn, Douglas and Hirschfield, Gideon M and Cordell, Heather J and Alexander, Graeme J and Jones, David E.J and Sandford, Richard N and Mells, George F and Jones, David and Kirby, John and Hirschfield, Gideon and Alexander, Graeme and Sandford, Richard and Taylor‐Robinson, Simon and Ch'ng, Chin Lye and Rahman, Mesbah and Yapp, Tom and Sturgess, Richard and Healey, Christopher and Czajkowski, Marek and Gunasekera, Anton and Gyawali, Pranab and Premchand, Purushothaman and Kapur, Kapil and Marley, Richard and Foster, Graham and Watson, Alan and Dias, Aruna and Subhani, Javaid and Harvey, Rory and McCorry, Roger and Ramanaden, David and Gasem, Jaber and Evans, Richard and Mathialahan, Thiriloganathan and Shorrock, Christopher and Lipscomb, George and Southern, Paul and Tibble, Jeremy and Gorard, David and Palegwala, Altaf and Jones, Susan and Dawwas, Mohamed and Dolwani, Sunil and Prince, Martin and Foxton, Matthew and Elphick, David and Mitchison, Harriet and Gooding, Ian and Karmo, Mazn and Saksena, Sushma and Mendall, Mike and Patel, Minesh and Ede, Roland and Austin, Andrew and Sayer, Joanna and Hankey, Lorraine and Hovell, Christopher and Fisher, Neil and Carter, Martyn and Koss, Konrad and Piotrowicz, Andrzej and Grimley, Charles and Neal, David and Lim, Guan and Levi, Sass and Ala, Aftab and Broad, Andrea and Saeed, Athar and Wood, Gordon and Brown, Jonathan and Wilkinson, Mark and Gordon, Harriet and Ramage, John and Ridpath, Jo and Ngatchu, Theodore and Grover, Bob and Shaukat, Syed and Shidrawi, Ray and Abouda, George and Ali, Faiz and Rees, Ian and Salam, Imroz and Narain, Mark and Brown, Ashley and ... and UK-PBC Consortium
Hepatology, ISSN 0270-9139, 03/2016, Volume 63, Issue 3, pp. 930 - 950
Journal Article
by Schmidt, Amand F, Dr and Swerdlow, Daniel I, PhD and Holmes, Michael V, PhD and Patel, Riyaz S, MD and Fairhurst-Hunter, Zammy, MSc and Lyall, Donald M, PhD and Hartwig, Fernando Pires, MSc and Horta, Bernardo Lessa, Prof and Hyppönen, Elina, Prof and Power, Christine, Prof and Moldovan, Max, PhD and van Iperen, Erik, MSc and Hovingh, G Kees, Prof and Demuth, Ilja, PhD and Norman, Kristina, PhD and Steinhagen-Thiessen, Elisabeth, Prof and Demuth, Juri, PhD and Bertram, Lars, Prof and Liu, Tian, PhD and Coassin, Stefan, PhD and Willeit, Johann, Prof and Kiechl, Stefan, MD and Willeit, Karin, MD and Mason, Dan, PhD and Wright, John, Prof and Morris, Richard, Prof and Wanamethee, Goya, Prof and Whincup, Peter, Prof and Ben-Shlomo, Yoav, Prof and McLachlan, Stela, PhD and Price, Jackie F, Prof and Kivimaki, Mika, Prof and Welch, Catherine, PhD and Sanchez-Galvez, Adelaida, PhD and Marques-Vidal, Pedro, PhD and Nicolaides, Andrew, PhD and Panayiotou, Andrie G, PhD and Onland-Moret, N Charlotte, PhD and van der Schouw, Yvonne T, Prof and Matullo, Giuseppe, PhD and Fiorito, Giovanni, PhD and Guarrera, Simonetta, MSc and Sacerdote, Carlotta, PhD and Wareham, Nicholas J, Prof and Langenberg, Claudia, PhD and Scott, Robert, PhD and Luan, Jian'an, PhD and Bobak, Martin, Prof and Malyutina, Sofia, Prof and Pająk, Andrzej, PhD and Kubinova, Ruzena, PhD and Tamosiunas, Abdonas, Prof and Pikhart, Hynek, PhD and Husemoen, Lise Lotte Nystrup, PhD and Grarup, Niels, PhD and Pedersen, Oluf, PhD and Hansen, Torben, PhD and Linneberg, Allan, Prof and Simonsen, Kenneth Starup, PhD and Cooper, Jackie, MSc and Humphries, Steve E, Prof and Brilliant, Murray, PhD and Kitchner, Terrie, CCRP and Hakonarson, Hakon, PhD and Carrell, David S, PhD and McCarty, Catherine A, PhD and Kirchner, H Lester, PhD and Larson, Eric B, MD and Crosslin, David R, PhD and de Andrade, Mariza, Prof and Roden, Dan M, Prof and Denny, Joshua C, MD and Carty, Cara, PhD and Hancock, Stephen, MSciStud and Attia, John, PhD and Holliday, Elizabeth, PhD and O'Donnell, Martin, PhD and Yusuf, Salim, Prof and Chong, Michael, MSc and Pare, Guillaume, Prof and van der Harst, Pim, Prof and Said, M Abdullah, BSc and Eppinga, Ruben N, PhD and Verweij, Niek, PhD and Snieder, Harold, Prof and Christen, Tim, MSc and Mook-Kanamori, Dennis O, PhD and Gustafsson, Stefan, PhD and Lind, Lars, Prof and Ingelsson, Erik, Prof and Pazoki, Raha, PhD and Franco, Oscar, PhD and Hofman, Albert, Prof and Uitterlinden, Andre, PhD and Dehghan, Abbas, PhD and Teumer, Alexander, PhD and Baumeister, Sebastian, PhD and Dörr, Marcus, Prof and Lerch, Markus M, Prof and Völker, Uwe, Prof and ... and UCLEB consortium and LifeLines Cohort study group and UCLEB Consortium and LifeLines Cohort Study Grp and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Lancet Diabetes & Endocrinology, The, ISSN 2213-8587, 2017, Volume 5, Issue 2, pp. 97 - 105
Journal Article