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1. Management of hematologic malignancies
by O'Brien, Susan and Vose, Julie M and Kantarjian, Hagop M
2011, 1, ISBN 9780521896405, 527
Hematologic malignancies were the first human cancers to be studied in depth at the molecular level, and recent years have seen important advances in... 
Clinical & internal medicine | Lymphoproliferative disorders | Treatment | Hematological oncology | Lymphomas
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2. Introduction to occupational therapy
by O'Brien, Jane Clifford and Sabonis-Chafee, Barbara and Hussey, Susan M
2012, 4th ed., ISBN 9780323084659, xii, 218
Occupational Therapy
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3. Full Text Laparoscopic Adjustable Gastric Banding in Severely Obese Adolescents: A Randomized Trial
by O’Brien, Paul E and Sawyer, Susan M and Laurie, Cheryl and Brown, Wendy A and Skinner, Stewart and Veit, Friederike and Paul, Eldho and Burton, Paul R and McGrice, Melanie and Anderson, Margaret and Dixon, John B
JAMA, ISSN 0098-7484, 02/2010, Volume 303, Issue 6, pp. 519 - 526
CONTEXT Adolescent obesity is a common and serious health problem affecting more than 5 million young people in the United States alone. Bariatric surgery is... 
POPULATION | MEDICINE, GENERAL & INTERNAL | HOMEOSTASIS MODEL ASSESSMENT | RISK-FACTORS | MANAGEMENT | INSULIN-RESISTANCE | GLUCOSE | OVERWEIGHT | WEIGHT-LOSS | BARIATRIC SURGERY | CHILD HEALTH QUESTIONNAIRE | Obesity - surgery | Reoperation | Life Style | Prospective Studies | Humans | Male | Treatment Outcome | Laparoscopy | Gastroplasty - adverse effects | Gastroplasty - methods | Weight Loss | Adolescent | Quality of Life | Female | Health Status | Obesity | Weight control | Teenagers | Gastrointestinal surgery | Medical treatment
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4. Full Text Inotuzumab ozogamicin versus standard of care in relapsed or refractory acute lymphoblastic leukemia: Final report and long‐term survival follow‐up from the randomized, phase 3 INO‐VATE study
by Kantarjian, Hagop M and DeAngelo, Daniel J and Stelljes, Matthias and Liedtke, Michaela and Stock, Wendy and Gökbuget, Nicola and O’Brien, Susan M and Jabbour, Elias and Wang, Tao and Liang White, Jane and Sleight, Barbara and Vandendries, Erik and Advani, Anjali S
Cancer, ISSN 0008-543X, 07/2019, Volume 125, Issue 14, pp. 2474 - 2487
All key subgroups of patients with relapsed or refractory CD22‐positive B‐cell precursor acute lymphoblastic leukemia have the potential to benefit from... 
hematopoietic stem cell transplantation | remission induction | acute lymphoblastic leukemia | hepatic veno‐occlusive disease | inotuzumab ozogamicin | adults | hepatic veno-occlusive disease | THERAPY | ONCOLOGY | CHEMOTHERAPY | CD22 | Acute lymphatic leukemia | Leukemia | Minimal residual disease | Antibodies | Stem cell transplantation | Transplantation | Lymphatic leukemia | Risk analysis | Survival | Hematopoietic stem cells | Subgroups | Risk factors | Hemopoiesis | Confidence intervals | Refractory materials | Chemotherapy | Randomization | Lymphocytes B | Stem cells | Remission | Adults | Original
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5. Full Text Sustained long-lasting responses after lenalidomide discontinuation in patients with chronic lymphocytic leukemia
by Strati, Paolo and Ferrajoli, Alessandra and Wierda, William G and Jain, Nitin and Thompson, Philip A and O’Brien, Susan M and Rezvani, Katy and Kantarjian, Hagop M and Burger, Jan A and Hinojosa, Christina O and Keating, Michael J and Estrov, Zeev
Leukemia, ISSN 0887-6924, 10/2018, Volume 32, Issue 10, pp. 2278 - 2281
CELLS | CLL | ONCOLOGY | CYCLOPHOSPHAMIDE | RITUXIMAB | OUTCOMES | 1ST-LINE THERAPY | HEMATOLOGY | FLUDARABINE | Drug therapy | Development and progression | Chronic lymphocytic leukemia | Chronic lymphatic leukemia | Leukemia | Lymphatic leukemia
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6. Full Text Clinical implications of the 2018 iwCLL Guidelines update
by O'Brien, Susan M
Clinical advances in hematology & oncology : H&O, ISSN 1543-0790, 08/2018, Volume 16, Issue 8, pp. 1 - 16
Leukemia, Lymphocytic, Chronic, B-Cell - therapy | Humans | Leukemia, Lymphocytic, Chronic, B-Cell - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis | Practice Guidelines as Topic
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7. Full Text The impact of complex karyotype on the overall survival of patients with relapsed chronic lymphocytic leukemia treated with idelalisib plus rituximab
by Kreuzer, Karl-Anton and Furman, Richard R and Stilgenbauer, Stephan and Dubowy, Ronald L and Kim, Yeonhee and Munugalavadla, Veerendra and Lilienweiss, Esther and Reinhardt, Hans Christian and Cramer, Paula and Eichhorst, Barbara and Hillmen, Peter and O'Brien, Susan M and Pettitt, Andrew R and Hallek, Michael
Leukemia, ISSN 0887-6924, 08/2019
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8. Full Text Highlights in chronic lymphocytic leukemia from the 2018 American Society of Clinical Oncology Annual Meeting: commentary
by O'Brien, Susan M
Clinical advances in hematology & oncology : H&O, ISSN 1543-0790, 07/2018, Volume 16, Issue 7, pp. 14 - 15
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9. Full Text Acute lymphoblastic leukemia in adolescents and young adults
: ALL in AYA Patients
by Rytting, Michael E and Jabbour, Elias J and O'Brien, Susan M and Kantarjian, Hagop M
Cancer, ISSN 0008-543X, 07/2017, Volume 123, Issue 13, pp. 2398 - 2403
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10. Full Text Highlights in chronic lymphocytic leukemia from the 2017 American Society of Hematology Annual Meeting: commentary
by O'Brien, Susan M
Clinical advances in hematology & oncology : H&O, ISSN 1543-0790, 01/2018, Volume 16, Issue 1, pp. 16 - 19
Leukemia, Lymphocytic, Chronic, B-Cell - therapy | Recurrence | Humans | Leukemia, Lymphocytic, Chronic, B-Cell - etiology | Drug Resistance, Neoplasm | Treatment Outcome | Disease Management | Leukemia, Lymphocytic, Chronic, B-Cell - mortality | Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis
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11. Full Text A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL
by Jain, Nitin and Balakrishnan, Kumudha and Ferrajoli, Alessandra and O'Brien, Susan M and Burger, Jan A and Kadia, Tapan M and Cortes, Jorge E and Ayres, Mary L and Tambaro, Francesco Paolo and Keating, Michael J and Gandhi, Varsha and Wierda, William G
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 13, pp. 22104 - 22112
Chemoimmunotherapy regimens have been the standard first-line therapy for patients with chronic lymphocytic leukemia (CLL). For young, fit patients the... 
Rituximab | CLL | Bendamustine | Fludarabine | Chemoimmunotherapy | chemoimmunotherapy | MULTICENTER | CYCLOPHOSPHAMIDE | REGIMEN | OPEN-LABEL | COMBINATION | CELL BIOLOGY | INHIBITION | INITIAL THERAPY | fludarabine | CHRONIC LYMPHOCYTIC-LEUKEMIA | DNA-REPAIR | rituximab | bendamustine | Prognosis | Follow-Up Studies | Humans | Middle Aged | Male | Survival Rate | Vidarabine - analogs & derivatives | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | Rituximab - administration & dosage | Bendamustine Hydrochloride - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged, 80 and over | Female | Aged | Vidarabine - administration & dosage | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Neoplasm Staging
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12. Full Text Highlights From the XVII International Workshop on Chronic Lymphocytic Leukemia: Commentary
by O'Brien, Susan M
Clinical advances in hematology & oncology : H&O, ISSN 1543-0790, 07/2017, Volume 15, Issue 7, pp. 13 - 15
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13. Full Text Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia
by Furman, Richard R and Sharman, Jeff P and Coutre, Steven E and Cheson, Bruce D and Pagel, John M and Hillmen, Peter and Barrientos, Jacqueline C and Zelenetz, Andrew D and Kipps, Thomas J and Flinn, Ian and Ghia, Paolo and Eradat, Herbert and Ervin, Thomas and Lamanna, Nicole and Coiffier, Bertrand and Pettitt, Andrew R and Ma, Shuo and Stilgenbauer, Stephan and Cramer, Paula and Aiello, Maria and Johnson, Dave M and Miller, Langdon L and Li, Daniel and Jahn, Thomas M and Dansey, Roger D and Hallek, Michael and O'Brien, Susan M
The New England Journal of Medicine, ISSN 0028-4793, 03/2014, Volume 370, Issue 11, pp. 997 - 1007
A placebo-controlled study of idelalisib in patients with relapsed chronic lymphocytic leukemia who were receiving rituximab was stopped early because of... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | CAL-101 | PI3K | MUTATION | DISEASE | GENOMIC ABERRATIONS | INHIBITOR | EXPRESSION | Recurrence | Lymph Nodes - pathology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Leukemia, Lymphocytic, Chronic, B-Cell - complications | Aged, 80 and over | Female | Kidney Diseases - complications | Purines - adverse effects | Purines - therapeutic use | Double-Blind Method | Kaplan-Meier Estimate | Rituximab | Class Ia Phosphatidylinositol 3-Kinase - antagonists & inhibitors | Disease-Free Survival | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - mortality | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Quinazolinones - therapeutic use | Antibodies, Monoclonal, Murine-Derived - adverse effects | Quinazolinones - adverse effects | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Chronic lymphocytic leukemia | Care and treatment | Medical research | Chronic lymphatic leukemia | Chemotherapy | Renal function | Leukemia | Myelosuppression | Lymphatic leukemia | Kinases | Drug therapy | Survival | 1-Phosphatidylinositol 3-kinase
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14. Full Text BTK Inhibitors for the Treatment of Chronic Lymphocytic Leukemia
by Strati, Paolo and OʼBrien, Susan M
Oncology Times, ISSN 0276-2234, 09/2019, Volume 41, Issue 17, pp. 1 - 29
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15. Full Text Considerations in the frontline treatment of chronic lymphocytic leukemia
by O’Brien, Susan M
Clinical Advances in Hematology and Oncology, ISSN 1543-0790, 12/2016, Volume 14, Issue 12, pp. 970 - 973
Leukemia, Lymphocytic, Chronic, B-Cell - therapy | Standard of Care | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Humans | Immunotherapy
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16. Full Text Fludarabine, cyclophosphamide, and rituximab treatment achieves long-Term disease-free survival in IGHV-mutated chronic lymphocytic leukemia
by Thompson, Philip A and Tam, Constantine S and O'Brien, Susan M and Wierda, William G and Stingo, Francesco and Plunkett, William and Smith, Susan C and Kantarjian, Hagop M and Freireich, Emil J and Keating, Michael J
Blood, ISSN 0006-4971, 01/2016, Volume 127, Issue 3, pp. 303 - 309
Accurate identification of patients likely to achieve long-progression-free survival (PFS) after chemoimmunotherapy is essential given the availability of less... 
DIAGNOSIS | INITIAL THERAPY | GUIDELINES | IBRUTINIB | REGIMEN | OPEN-LABEL | MUTATIONS | HEMATOLOGY | Recurrence | Cyclophosphamide - administration & dosage | Prognosis | Humans | Middle Aged | Male | Neoplasms, Second Primary - mortality | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Cause of Death | Incidence | Neoplasm, Residual | Young Adult | Aged, 80 and over | Adult | Female | Treatment Outcome | Vidarabine - analogs & derivatives | Remission Induction | Neoplasms, Second Primary - epidemiology | Neoplasms, Second Primary - etiology | Rituximab - administration & dosage | Retreatment | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Survival Analysis | Aged | Leukemia, Lymphocytic, Chronic, B-Cell - mortality | Vidarabine - administration & dosage | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mutation | Neoplasm Staging | Immunoglobulin Heavy Chains - genetics | Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis | Index Medicus | Abridged Index Medicus | Clinical Trials and Observations
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17. Full Text VIII. Treatment of chronic lymphocytic leukaemia, where are we heading?
: Treatment of CLL
by O'Brien, Susan M
Hematological Oncology, ISSN 0278-0232, 06/2015, Volume 33, pp. 46 - 49
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18. Full Text The Immune Landscape of Cancer
by Thorsson, Vesteinn and Thorsson, Vésteinn and Gibbs, Richard A and Gibbs, David L and Brown, Scott D and Wolf, Gregory and Wolf, Denise and Bortone, Dante S and Ou Yang, Tai-Hsien and Porta-Pardo, Eduard and Gao, Galen F and Gao, Jianjiong and Plaisier, Christopher L and Eddy, James A and Ziv, Elad and Culhane, Aedin C and Paull, Evan O and Sivakumar, I.K. Ashok and Gentles, Andrew J and Malhotra, Raunaq and Farshidfar, Farshad and Colaprico, Antonio and Parker, Joel S and Mose, Lisle E and Vo, Nam Sy and Liu, Wenbin and Liu, Jianfang and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Rader, Janet and Dhankani, Varsha and Reynolds, Sheila and Reynolds, Sheila M and Bowlby, Reanne and Califano, Andrea and Cherniack, Andrew D and Anastassiou, Dimitris and Bedognetti, Davide and Mokrab, Younes and Newman, Aaron M and Rao, Arvind and Chen, Amy and Chen, Chu and Chen, Ken and Krasnitz, Alexander and Hu, Jianhong and Hu, Hai and Malta, Tathiane M and Noushmehr, Houtan and Pedamallu, Chandra Sekhar and Bullman, Susan and Ojesina, Akinyemi I and Lamb, Andrew and Zhou, Wanding and Shen, Hui and Choueiri, Toni K and Weinstein, John N and Guinney, Justin and Saltz, Joel and Holt, Robert and Holt, Robert A and Rabkin, Charles S and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jioajiao and Wang, Min and Wang, Linghua and Wang, Zhining and Wang, Timothy and Wang, Jing and Yang, Ju Dong and Yang, Hannah and Yang, Liming and Yang, Ian and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Jiexin and Zhang, Lizhi and Zhang, Wei and Zhang, Hongzheng and Zhang, Hailei and Zhang, Hongxin and Chudamani, Sudha and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Yichao and Sun, Qiang and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Immunity, ISSN 1074-7613, 04/2018, Volume 48, Issue 4, pp. 812 - 830.e14
We performed an extensive immunogenomic analysis of more than 10,000 tumors comprising 33 diverse cancer types by utilizing data compiled by TCGA. Across... 
tumor immunology | immunotherapy | cancer genomics | integrative network analysis | immuno-oncology | tumor microenvironment | immune subtypes | immunomodulatory | GENOMIC ANALYSES | INFORMATION | T-CELL-RECEPTOR | REGULATORY NETWORK | CLASSIFICATION | IMMUNOLOGY | SEQUENCING DATA | SOMATIC MUTATIONS | COMPREHENSIVE ANALYSIS | PREDICTION | REVEALS | Transforming Growth Factor beta - immunology | Prognosis | Humans | Middle Aged | Th1-Th2 Balance - physiology | Male | Neoplasms - classification | Wound Healing - immunology | Young Adult | Transforming Growth Factor beta - genetics | Neoplasms - genetics | Neoplasms - immunology | Interferon-gamma - immunology | Adolescent | Aged, 80 and over | Adult | Female | Aged | Interferon-gamma - genetics | Wound Healing - genetics | Genomics - methods | Child | Macrophages - immunology | Cell proliferation | Cluster analysis | Transcription | Copy number | p53 Protein | Lung cancer | Genomics | Aneuploidy | Lymphocytes T | Genomes | Cell interactions | Macrophages | Immunotherapy | DNA methylation | Deoxyribonucleic acid--DNA | Immune system | Medical research | Wound healing | Immunomodulation | MiRNA | Stockholders | Inflammation | T cell receptors | Communications networks | Gene expression | White blood cells | Inventors | Medical prognosis | γ-Interferon | Mutation | Cancer | Tumors | Immune Subtypes | Integrative Network Analysis | Cancer Genomics | Immuno-oncology | Tumor immunology
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