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Journal Article
Chemical Science, ISSN 2041-6520, 12/2015, Volume 6, Issue 12, pp. 6813 - 6822
IspH forms fusion hybrids with RPS1 as well as UbiA, examples of Rosetta stone proteins. The protein IspH, ( E )-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate... 
Chemistry
Journal Article
ACS Catalysis, ISSN 2155-5435, 05/2018, Volume 8, Issue 5, pp. 4299 - 4312
We report the results of an investigation into the catalytic role of highly conserved amide-containing (asparagine, glutamine) and OH-containing (serine,... 
cis- and trans-prenyltransferases | isoprenoid biosynthesis | X-ray crystallography | quantum chemistry | proton shuttle | dehydrosqualene synthase | Isoprenoid biosynthesis
Journal Article
Journal Article
ISSN 2041-6520, 11/2015, Volume 6, Issue 12, pp. 6813 - 6822
The protein IspH, ( E )-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMPPP) reductase, is an essential 4Fe-4S cluster-containing protein in the... 
Journal Article
Journal Article
ChemBioChem, ISSN 1439-4227, 05/2017, Volume 18, Issue 10, pp. 882 - 882
The inside cover picture shows the structure of the isoprenoid biosynthesis enzyme IspH with a newly discovered drug‐like inhibitor, a lipophilic barbiturate.... 
HYSCORE | IspH | in silico | NRVS | isoprenoid | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | Vector-borne diseases | Phosphates | Lipophilic | Herbicides | Enzymes | Inhibitors | Malaria | Computer applications | Ligands | Biosynthesis | Parasites
Journal Article
Journal Article
ChemBioChem: a European journal of chemical biology, ISSN 1439-4227, 04/2017, Volume 18, Issue 10
Isoprenoid biosynthesis is an important area for anti-infective drug development. One isoprenoid target described is (E)-1-hydroxy-2-methyl-but-2-enyl... 
INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Journal Article
Chemical Science, ISSN 2041-6520, 2015, Volume 6, Issue 12, pp. 6813 - 6822
The protein IspH, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMPPP) reductase, is an essential 4Fe-4S cluster-containing protein in the methylerythritol... 
LYTB GENE | METHYLERYTHRITOL PHOSPHATE-PATHWAY | ISOPRENOID BIOSYNTHESIS | PLASMODIUM-FALCIPARUM | MECHANISTIC INSIGHTS | STRINGENT RESPONSE | SEQUENCE SIMILARITY NETWORKS | ESCHERICHIA-COLI | (E)-4-HYDROXY-3-METHYLBUT-2-ENYL DIPHOSPHATE REDUCTASE | CHEMISTRY, MULTIDISCIPLINARY | MASS-SPECTROMETRY
Journal Article
Chemical Science, ISSN 2041-6520, 11/2015, Volume 6, Issue 12, pp. 6813 - 6822
The protein IspH, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate (HMPPP) reductase, is an essential 4Fe-4S cluster-containing protein in the methylerythritol... 
Proteins | Pathogens | Anaerobes | Similarity | Bacteria | Organisms | Catalysis | Stone
Journal Article
ACS chemical biology, ISSN 1554-8929, 5/2016, Volume 11, Issue 5, pp. 1362 - 1371
Trypanosomatid parasites are the causative agents of many neglected tropical diseases including the leishmaniases, Chagas disease, and human African... 
Journal Article
Developmental Neuroscience, ISSN 0378-5866, 07/2015, Volume 37, Issue 4-5, pp. 464 - 464
  No abstract available 
Further Section
Journal Article
Developmental Neuroscience, ISSN 0378-5866, 07/2015, Volume 37, Issue 4-5, pp. 465 - 465
  No abstract available 
Further Section
Journal Article
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