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Nature, ISSN 0028-0836, 03/2011, Volume 471, Issue 7336, pp. 110 - 114
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 06/2007, Volume 356, Issue 25, pp. 2591 - 2602
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 02/2004, Volume 303, Issue 5662, pp. 1371 - 1374
Journal Article
Science, ISSN 0036-8075, 2/2004, Volume 303, Issue 5662, pp. 1371 - 1374
Journal Article
Nature, ISSN 0028-0836, 08/2004, Volume 430, Issue 7000, pp. 694 - 699
NF-κB transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-α and interleukin-1β. Failure to downregulate... 
TNF RECEPTOR | DEUBIQUITINATING ENZYME | RECRUITMENT | ACTIVATION | MULTIDISCIPLINARY SCIENCES | ZINC-FINGER PROTEIN | IKK | KINASE RIP | TRAF2 | CYSTEINE PROTEASES | CELL-DEATH
Journal Article
CLINICAL CANCER RESEARCH, ISSN 1078-0432, 03/2019, Volume 25, Issue 5, pp. 1574 - 1587
Purpose: To determine whether inhibition of mTORkinase-mediated signaling represents a valid therapeutic approach for chronic lymphocytic leukemia (CLL).... 
MAMMALIAN TARGET | IN-VITRO | AZD8055 | BRUTON TYROSINE KINASE | EVEROLIMUS | ONCOLOGY | RESISTANCE | CHRONIC LYMPHOCYTIC-LEUKEMIA | AKT | COMBINATION | EXPRESSION | mTOR inhibition | CLL | BCR signaling | FOXO1
Journal Article
Science (Washington), ISSN 0036-8075, 02/2004, Volume 303, Issue 5662, pp. 1371 - 1374
Arabidopsis thaliana De-etiolated-1 (AtDET1) is a highly conserved protein, with orthologs in vertebrate and invertebrate organisms. AtDET1 negatively... 
Journal Article
Nature, ISSN 0028-0836, 08/2004, Volume 430, Issue 7000, pp. 694 - 699
NF-B transcription factors mediate the effects of pro-inflammatory cytokines such as tumour necrosis factor-[alpha] and interleukin-1[beta1]. Failure to... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/1998, Volume 273, Issue 10, pp. 5841 - 5845
Journal Article
Biochemical Journal, ISSN 0264-6021, 06/2002, Volume 364, Issue 2, pp. 579 - 585
We have recently proposed that disulphide S-monoxides (thiosulphinates) and disulphide S-dioxides (thiosulphonates) are formed from their parent disulphides... 
Disulphide S-oxides | Oxidative stress | Reactive sulphur species | Sulphur proteins | Glutathione - chemistry | Antioxidants - chemistry | Oxidation-Reduction | Disulfides - chemistry | Oxides - chemistry
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 06/2002, Volume 364, Issue 2, pp. 579 - 585
We have recently proposed that disulphide S-monoxides (thiosulphinates) and disulphide S-dioxides (thiosulphonates) are formed from their parent disulphides... 
RAT-LIVER | METALLOTHIONEIN | disulphide S-oxides | PROTECTION | PEROXYNITRITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DISULFIDE | reactive sulphur species | ZINC | METABOLISM | GLUTATHIONE | ENZYMES | sulphur proteins | DERIVATIVES | oxidative stress
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2010, Volume 107, Issue 21, p. 9771
  Macrophages respond to cytosolic nucleic acids by activating cysteine protease caspase-1 within a complex called the inflammasome. Subsequent cleavage and... 
Pathogens | Cytokines | Proteases | Rodents | Genes | Comparative analysis | Cancer
Journal Article
British Journal of Haematology, ISSN 0007-1048, 10/2001, Volume 115, Issue 1, p. 140
Journal Article