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PLoS ONE, ISSN 1932-6203, 06/2014, Volume 9, Issue 6, pp. e100738 - e100738
Neoadjuvant chemoradiation therapy (CRT) is increasingly the standard of care for locally advanced oesophageal cancer. A complete pathological response to CRT... 
GENOMIC INSTABILITY | OXIDATIVE STRESS | MULTIDISCIPLINARY SCIENCES | NEOADJUVANT CHEMORADIOTHERAPY | PREOPERATIVE CHEMORADIOTHERAPY | IONIZING-RADIATION | DNA-REPAIR | EXPRESSION | COLON-CANCER-CELLS | EXPOSURE | HUMAN-TUMOR XENOGRAFTS | Mitochondrial Size - drug effects | Adenocarcinoma - pathology | Humans | Middle Aged | Male | Chemoradiotherapy, Adjuvant | Mutagenesis - drug effects | Esophageal Neoplasms - pathology | Mitochondrial Size - radiation effects | Adenocarcinoma - metabolism | Mutagenesis - radiation effects | Esophageal Neoplasms - metabolism | Energy Metabolism - radiation effects | Mitochondria - radiation effects | Adult | Female | Esophageal Neoplasms - therapy | Treatment Outcome | Mitochondria - metabolism | Mitochondria - drug effects | Radiation Tolerance - drug effects | Adenocarcinoma - therapy | Cell Line, Tumor | Aged | Energy Metabolism - drug effects | Adenocarcinoma | Glucose metabolism | Genetic aspects | Gene expression | Analysis | Esophageal cancer | Oxidative stress | Energy metabolism | Phosphorylation | Oxidative metabolism | Radiation | Radioresistance | Genomes | Mitochondrial DNA | Kinases | Cancer therapies | Mitochondria | Alterations | Energy | Bioenergetics | Surgery | Cell cycle | Pretreatment | Deoxyribonucleic acid--DNA | Radiation therapy | Metabolism | Esophagus | Pathology | Gene amplification | Oxidative phosphorylation | Medical prognosis | Glycolysis | Mutation | Electron transport | Cancer | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, pp. e27944 - e27944
Inflammatory mediators in the tumour microenvironment promote tumour growth, vascular development and enable evasion of anti-tumour immune responses, by... 
MIGRATION | ACTIVATION | FUNCTIONAL MATURATION | ANGIOGENESIS | VEGF | MULTIDISCIPLINARY SCIENCES | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | CXC CHEMOKINES | G-CSF | T-CELLS | ENDOTHELIAL GROWTH-FACTOR | Antigens, CD - immunology | Immunoglobulins - immunology | Membrane Glycoproteins - metabolism | Chemokine CCL2 - immunology | Coculture Techniques | Dendritic Cells - immunology | Humans | Culture Media, Conditioned - pharmacology | Male | Vascular Endothelial Growth Factor A - metabolism | Chemokine CXCL5 - metabolism | Interferon-gamma - metabolism | Chemokine CXCL1 - pharmacology | Lipopolysaccharides - immunology | Antigens, CD - metabolism | Immunoglobulins - metabolism | Chemokine CXCL5 - pharmacology | Flow Cytometry | Female | Chemokine CCL2 - metabolism | Membrane Glycoproteins - immunology | B7-2 Antigen - immunology | Chemokine CXCL1 - metabolism | HLA-DR Antigens - metabolism | Vascular Endothelial Growth Factor A - pharmacology | Colorectal Neoplasms - metabolism | Dendritic Cells - metabolism | Tumor Microenvironment - drug effects | Enzyme-Linked Immunosorbent Assay | Intercellular Adhesion Molecule-1 - immunology | Tissue Culture Techniques | Cells, Cultured | Vascular Endothelial Growth Factor A - immunology | Tumor Microenvironment - immunology | B7-2 Antigen - metabolism | Cell Differentiation - immunology | Chemokine CXCL1 - immunology | Intercellular Adhesion Molecule-1 - metabolism | Colorectal Neoplasms - immunology | Chemokine CCL2 - pharmacology | Cell Differentiation - drug effects | Chemokine CXCL5 - immunology | Interferon-gamma - immunology | Lipopolysaccharides - pharmacology | Aged | HLA-DR Antigens - immunology | Colorectal Neoplasms - pathology | Culture Media, Conditioned - metabolism | Care and treatment | Dendritic cells | Vascular endothelial growth factor | Colorectal cancer | Tumors | CD86 antigen | Colorectal carcinoma | Biochemistry | Metastasis | Kinases | Lipopolysaccharides | Proteins | Angiogenesis | Signal transduction | Lymphocytes | Inhibition | Pretreatment | Conditioning | Antigens | Immune response | Cytokines | Maturation | Secretion | Neutrophils | Interleukin 12 | CD80 antigen | Inflammation | CD83 antigen | Interleukin 10 | Ligands | Histocompatibility antigen HLA | Prostate cancer | Chemokines | Monocyte chemoattractant protein 1 | Cancer | Apoptosis | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 10/2016, Volume 6, Issue 1, pp. 34523 - 34523
Colorectal cancer (CRC) is a leading cause of cancer deaths. Molecularly targeted therapies (e.g. bevacizumab) have improved survival rates but drug resistance... 
TARGETED THERAPY | CAPECITABINE | ANTIANGIOGENIC COMPOUNDS | ZEBRAFISH | ANGIOGENESIS | BEVACIZUMAB | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GROWTH | ANTITUMOR-ACTIVITY | FLUOROURACIL | Cell Line | Gene Expression | Humans | Zebrafish | Antineoplastic Agents - therapeutic use | Interleukin-6 - secretion | Neovascularization, Pathologic - complications | Vascular Endothelial Growth Factor A - secretion | HT29 Cells | Xenograft Model Antitumor Assays | Animals | Colorectal Neoplasms - drug therapy | Phenols - therapeutic use | Blood Vessels - drug effects | Inflammation Mediators - metabolism | Angiogenesis Inhibitors - therapeutic use | Interleukin-8 - secretion | Colorectal Neoplasms - complications | Mice, Inbred BALB C | Neovascularization, Pathologic - metabolism | Quinolines - therapeutic use | Colorectal Neoplasms - pathology | Colorectal Neoplasms - metabolism | Endothelial Cells - drug effects | Explants | Animal models | Cell survival | Leukocyte migration | Colorectal carcinoma | Colorectal cancer | Drug resistance | Secretions | Embryos | Survival | Molecular weight | Cell adhesion & migration | Bevacizumab | Interleukin 6 | Angiogenesis | Molecular modelling | Tumor necrosis factor | Xenografts | Phenols | Vascular endothelial growth factor | Monocyte chemoattractant protein 1 | Cell migration | Interleukin 8 | Tumors | Index Medicus
Journal Article
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 12/2014, Volume 14, Issue 1, pp. 907 - 907
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 04/2012, Volume 71, Issue 4, pp. 582 - 588
Background To examine the association between mitochondrial mutagenesis and the proinflammatory microenvironment in patients with inflammatory arthritis.... 
RHEUMATOID-ARTHRITIS | GENOMIC INSTABILITY | OXIDATIVE STRESS | ACTIVATION | JOINT DESTRUCTION | NECROSIS-FACTOR-ALPHA | MUTATIONS | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | HYPOXIA | EXPRESSION | DNA, Mitochondrial - drug effects | </