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Immunity, ISSN 1074-7613, 10/2013, Volume 39, Issue 4, pp. 782 - 795
Journal Article
Nature, ISSN 0028-0836, 04/2015, Volume 520, Issue 7547, pp. 368 - 372
Drug resistance invariably limits the clinical efficacy of targeted therapy with kinase inhibitors against cancer(1,2). Here we show that targeted therapy with... 
CNS CELL-TYPES | MELANOMA | METASTASIS | MICROENVIRONMENT | TRANSLATIONAL PROFILING APPROACH | MULTIDISCIPLINARY SCIENCES | RAF INHIBITOR RESISTANCE | ACQUIRED-RESISTANCE | KINASE INHIBITORS | DRUG-RESISTANCE | CANCER CHEMORESISTANCE | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Clone Cells - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - pathology | Proto-Oncogene Proteins c-fos - deficiency | Adenocarcinoma - metabolism | Neoplasm Metastasis - drug therapy | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Proto-Oncogene Proteins c-akt - metabolism | Melanoma - metabolism | Tumor Microenvironment - drug effects | Cell Survival - drug effects | Melanoma - pathology | Down-Regulation - drug effects | Enzyme Activation - drug effects | Adenocarcinoma - drug therapy | Disease Progression | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Cell Movement - drug effects | Lung Neoplasms - secretion | Melanoma - secretion | Animals | Clone Cells - pathology | Metabolome - drug effects | Signal Transduction - drug effects | Neoplasm Metastasis - pathology | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Adenocarcinoma - secretion | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Drug Resistance, Neoplasm - drug effects | Antimitotic agents | Pharmaceutical research | Care and treatment | Oncology, Experimental | Dosage and administration | Research | Drug therapy | Drug resistance | Antineoplastic agents | Tumors | Cancer | Melanoma | Mutation | Metastasis | Kinases | Cancer therapies | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 03/2018, Volume 9, Issue 17, pp. 13565 - 13581
Tripartite motif (TRIM) proteins have been shown to play important roles in cancer development and progression by modulating cell proliferation or resistance... 
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 2010, Volume 130, Issue 4, pp. 1152 - 1157
Journal Article
Immunity, ISSN 1074-7613, 03/2016, Volume 44, Issue 3, pp. 698 - 711
Journal Article
Nature, ISSN 0028-0836, 1/2016, Volume 529, Issue 7586, pp. 298 - 306
Metastasis is the main cause of death from cancer. To colonize distant organs, circulating cancer cells must overcome many obstacles through mechanisms that we... 
metastatic colonization | organ specific metastasis | metastasis | Cancer
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 05/2018, Volume 360, Issue 6390, pp. 800 - 805
Journal Article
Nature, ISSN 0028-0836, 10/2015, Volume 526, Issue 7573, pp. 453 - 457
Activation of oncogenes by mechanisms other than genetic aberrations such as mutations, translocations, or amplifications is largely undefined. Here we report... 
GENE | CHROMATIN | MULTIDISCIPLINARY SCIENCES | FRAMEWORK | RECEPTOR | NEUROBLASTOMA | MUTATIONS | DNA-SEQUENCING DATA | IDENTIFICATION | SEQ | DISCOVERY | NIH 3T3 Cells | Cell Proliferation | Molecular Weight | Histones - chemistry | Humans | Receptor Protein-Tyrosine Kinases - biosynthesis | Molecular Sequence Data | RNA, Messenger - analysis | Isoenzymes - chemistry | RNA Polymerase II - metabolism | Neoplasms - genetics | HEK293 Cells | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Female | Lysine - metabolism | Transcription Initiation, Genetic | Gene Expression Regulation, Neoplastic - genetics | Oncogenes - genetics | Introns - genetics | Signal Transduction | Isoenzymes - genetics | RNA, Messenger - genetics | Neoplasms - enzymology | Protein Structure, Tertiary - genetics | Neoplasms - drug therapy | Animals | Receptor Protein-Tyrosine Kinases - genetics | Cell Transformation, Neoplastic | Alleles | Cell Line, Tumor | Mice | Histones - metabolism | Isoenzymes - biosynthesis | Methylation | Isoenzymes - antagonists & inhibitors | Receptor Protein-Tyrosine Kinases - chemistry | Development and progression | Genetic aspects | Genetic transcription | Health aspects | Oncogenes | Cancer | Proteins | Phosphorylation | Thyroid cancer | Genes | Melanoma | Tumorigenesis | Metastasis | Kinases | Cancer therapies | Binding sites | Tumors | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 113, Issue 26, pp. 6716 - 6725
Journal Article
Journal Article