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PLoS ONE, ISSN 1932-6203, 11/2018, Volume 13, Issue 11, pp. e0205195 - e0205195
Treprostinil is applied for pulmonary arterial hypertension (PAH) therapy. However, the mechanism by which the drug achieves its beneficial effects in PAH... 
C/EBP-ALPHA | ACTIVATION | GLUCOCORTICOID-RECEPTOR | SAFETY | MULTIDISCIPLINARY SCIENCES | IP RECEPTOR | PROLIFERATION | HYPERTENSION | INHALED TREPROSTINIL | PROSTACYCLIN ANALOGS | CAMP | Humans | Middle Aged | Familial Primary Pulmonary Hypertension - drug therapy | Becaplermin - blood | Male | Familial Primary Pulmonary Hypertension - blood | Pulmonary Artery - metabolism | Collagen Type I - genetics | Mitogen-Activated Protein Kinase 1 - genetics | Adult | Female | CCAAT-Enhancer-Binding Proteins - genetics | Vascular Remodeling - drug effects | Myocytes, Smooth Muscle - drug effects | Transforming Growth Factor beta1 - blood | Familial Primary Pulmonary Hypertension - pathology | Extracellular Matrix - drug effects | Familial Primary Pulmonary Hypertension - genetics | Transforming Growth Factor beta1 - genetics | Becaplermin - genetics | Pulmonary Artery - drug effects | Gene Expression Regulation - drug effects | Epoprostenol - analogs & derivatives | Cyclic AMP - biosynthesis | Signal Transduction - drug effects | Collagen Type IV - genetics | Cell Proliferation - drug effects | Connective Tissue Growth Factor - genetics | Fibronectins - genetics | Connective Tissue Growth Factor - blood | Epoprostenol - administration & dosage | Heart failure | Complications and side effects | Care and treatment | Usage | Treprostinil | Smooth muscle | Research | Pulmonary hypertension | Risk factors | Thoracic surgery | Collagen (type I) | Platelet-derived growth factor | Lung | Collagens | CCAAT/enhancer-binding protein | Remodeling | Kinases | Experiments | Fibronectin | Surgery | Cell cycle | Extracellular matrix | Collagen (type IV) | Growth factors | Deposition | Enzyme-linked immunosorbent assay | Hypertension | Secretion | Pulmonary arteries | Muscles | Cyclic AMP | Cip protein | Blood vessels | Connective tissue growth factor | Patients | Platelet-derived growth factor BB | Deoxyadenosine | Asthma | Cyclin-dependent kinase inhibitor p21 | Collagen | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 07/2018, Volume 115, Issue 30, pp. E7158 - E7165
Rhinoviruses (RVs) are responsible for the majority of upper airway infections; despite their high prevalence and the resulting economic burden, effective... 
Metabolomics | Antiviral therapy | Metabolism | Rhinovirus | GLUT1 | ACTIVATION | 2-DEOXYGLUCOSE | MULTIDISCIPLINARY SCIENCES | AIRWAY INFLAMMATION | 2-DEOXY-D-GLUCOSE | rhinovirus | GLUTAMINE-METABOLISM | UNFOLDED PROTEIN RESPONSE | metabolomics | GLUCOSE | HUMAN CYTOMEGALOVIRUS-INFECTION | GENE-EXPRESSION | metabolism | antiviral therapy | Virus Replication - drug effects | Picornaviridae Infections - drug therapy | Nucleotides - genetics | Glucose Transporter Type 1 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Rhinovirus - physiology | Phosphatidylinositol 3-Kinases - genetics | Animals | Glucose Transporter Type 1 - genetics | Lipogenesis - genetics | Deoxyglucose - pharmacology | Lipogenesis - drug effects | Nucleotides - biosynthesis | Female | Mice | Picornaviridae Infections - genetics | Virus Replication - physiology | Picornaviridae Infections - metabolism | Picornaviridae Infections - pathology | Genetic aspects | Host-virus relationships | Rhinoviruses | Health aspects | Glucose transporter | Intervention | Deprivation | Animal models | Target recognition | Viruses | Infections | Glucose | Cells | Deoxyglucose | 1-Phosphatidylinositol 3-kinase | Respiratory tract | Glycolysis | Replication | Inhibition | Lipogenesis | Antiviral drugs | Transporter | Viral infections | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167665 - e0167665
Introduction HPV positive patients suffering from head and neck cancer benefit from intensified radiotherapy when applied as a primary as well as an adjuvant... 
ACTIVATION | PROFILES | GENOMICS | PROTEIN | MULTIDISCIPLINARY SCIENCES | OROPHARYNGEAL CANCER | GROWTH | SQUAMOUS-CELL CARCINOMA | MARKERS | IMPROVED SURVIVAL | HUMAN-PAPILLOMAVIRUS | Prospective Studies | Carcinoma, Squamous Cell - metabolism | Humans | Middle Aged | Hedgehog Proteins - metabolism | Carcinoma, Squamous Cell - surgery | Male | Carcinoma, Squamous Cell - radiotherapy | Head and Neck Neoplasms - metabolism | Papillomaviridae - pathogenicity | Young Adult | Disease-Free Survival | Head and Neck Neoplasms - radiotherapy | Papillomavirus Infections - metabolism | Radiotherapy, Adjuvant - methods | Biomarkers, Tumor - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Adult | Female | Signal Transduction - physiology | Aged | Head and Neck Neoplasms - surgery | Sonic hedgehog | Usage | Head and neck cancer | Research | Radiotherapy | Papillomavirus infections | Health aspects | Immunohistochemistry | Data banks | Medical services | Genomes | Tissue analysis | Multivariate analysis | Kinases | Carcinogenesis | Signal transduction | Carcinogens | Human papillomavirus | Cell growth | Surgery | Bioindicators | Neck | Pretreatment | Head | Squamous cell carcinoma | Risk groups | Radiation therapy | Disease control | Survival | Patients | Patched protein | Pathology | Signaling | Hedgehog protein | Biomarkers | Cancer | Index Medicus
Journal Article
Strahlentherapie und Onkologie, ISSN 0179-7158, 3/2015, Volume 191, Issue 3, pp. 209 - 216
Journal Article
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 12557 - 10
Journal Article
Strahlentherapie und Onkologie, ISSN 0179-7158, 9/2014, Volume 190, Issue 9, pp. 832 - 838
Journal Article
Journal of Brachial Plexus and Peripheral Nerve Injury, ISSN 1749-7221, 12/2015, Volume 10, Issue 1, pp. e53 - e56
Abstract Introduction  The Pancoast syndrome (PS) has been termed after Henry Pancoast. Its neurologic core symptoms include pain, radicular sensory and motor... 
Case Report | Surgical resection | Brachial plexus | Lung cancer | Outcome | Nerve infiltration | Pancoast tumor | Neurology | Oncology | Postoperative period | Neurosurgery | Tumors
Journal Article
Matrix biology : journal of the International Society for Matrix Biology, ISSN 0945-053X, 07/2019
Metastasis is a major cause of death in cancer patients. The extracellular matrix molecule tenascin-C is a known promoter of metastasis, however the underlying... 
Journal Article
Journal Article
Strahlentherapie und Onkologie, ISSN 0179-7158, 03/2015, Volume 191, Issue 3, p. 209
In the literature, HPV infection and/or p16 positivity have been consistently demonstrated to correlate with improved response rates in oropharyngeal squamous... 
Care and treatment | Cancer patients | Chemotherapy | Squamous cell carcinoma | Analysis | Throat cancer | Health aspects | Papillomavirus infections | Cancer
Journal Article
Journal Article
The Journal of Pathology, ISSN 0022-3417, 09/2011, Volume 225, Issue 1, pp. 63 - 72
Journal Article
Strahlentherapie und Onkologie, ISSN 0179-7158, 09/2014, Volume 190, Issue 9, p. 832
HPV-infection, p16 positivity, and EGFR expression have been correlated with favorable responses of head and neck cancer patients treated with radiotherapy... 
Antimitotic agents | Cancer patients | Care and treatment | Chemotherapy | Analysis | Head and neck cancer | Radiotherapy | Antineoplastic agents | Health aspects | Papillomavirus infections | Cancer
Journal Article