X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
cancer (3) 3
index medicus (3) 3
ubiquitin (3) 3
biochemistry & molecular biology (2) 2
chemistry, medicinal (2) 2
discovery (2) 2
dubs (2) 2
hausp (2) 2
inhibitors (2) 2
proteases (2) 2
small-molecule inhibitor (2) 2
activates p53 (1) 1
allosteric properties (1) 1
antagonists (1) 1
antineoplastic agents - chemistry (1) 1
antineoplastic agents - pharmacology (1) 1
binding sites (1) 1
cell culture (1) 1
cell proliferation - drug effects (1) 1
crystal structure (1) 1
deubiquitinase (1) 1
deubiquitinating enzyme usp14 (1) 1
enzyme inhibitors - chemistry (1) 1
enzyme inhibitors - pharmacology (1) 1
expression (1) 1
hct116 cells (1) 1
humans (1) 1
inactivation (1) 1
letter (1) 1
mdm2 (1) 1
mdm2 protein (1) 1
myc (1) 1
optimization (1) 1
p53 (1) 1
potent (1) 1
proteasome (1) 1
roles (1) 1
small-molecule inhibitors (1) 1
stabilization (1) 1
target (1) 1
tumor cell lines (1) 1
ubiquitin thiolesterase - antagonists & inhibitors (1) 1
ubiquitin-specific proteinase (1) 1
ubiquitination (1) 1
usp14 (1) 1
usp28 (1) 1
usp7 (1) 1
usp7/hausp (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Chemical Biology, ISSN 1552-4450, 02/2018, Volume 14, Issue 2, pp. 118 - 125
Given the importance of ubiquitin-specific protease 7 (USP7) in oncogenic pathways, identification of USP7 inhibitors has attracted considerable interest.... 
INACTIVATION | DUBS | STABILIZATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HAUSP | ACTIVATES P53 | PROTEASES | Ubiquitin | Cell culture | MDM2 protein | Allosteric properties | Ubiquitin-specific proteinase | Inhibitors | Antagonists | Tumor cell lines | Binding sites | Optimization | Crystal structure | Cancer
Journal Article
Future Medicinal Chemistry, ISSN 1756-8919, 2018, Volume 10, Issue 15, pp. 1741 - 1743
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. LB-257 - LB-257
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 03/2018, Volume 9, Issue 3, pp. 238 - 243
Ubiquitin specific protease 7 (USP7, HAUSP) has become an attractive target in drug discovery due to the role it plays in modulating Mdm2 levels and... 
proteasome | USP7 | ubiquitination | Mdm2 | HAUSP | deubiquitinase | ubiquitin | p53 | CHEMISTRY, MEDICINAL | CANCER | DISCOVERY | POTENT | SMALL-MOLECULE INHIBITORS | USP7/HAUSP
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.