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Journal of Surgical Research, ISSN 0022-4804, 09/2019, Volume 241, pp. 254 - 263
Clinically, liver fibrosis and cholestasis are two major disease entities, ultimately leading to hepatic failure. Although autophagy plays a substantial role... 
Liver fibrosis | Cholestatic liver disease | p-JNK | Autophagy | Necrosis | PATHWAYS | SIGNAL | SURGERY | APOPTOSIS | REACTIVE OXYGEN | Immunohistochemistry | Liver diseases | Cell death | Analysis | Liver
Journal Article
Urology, ISSN 0090-4295, 09/2019, Volume 131, pp. 136 - 143
To determine if combined administration of LIMK2 and JNK inhibitors in a rat model of erectile dysfunction induced by cavernosal nerve (CN) injury could... 
FIBROSIS | APOPTOSIS | SMOOTH-MUSCLE | CORPORAL VENOOCCLUSIVE DYSFUNCTION | RESECTION | JNK | UROLOGY & NEPHROLOGY | RADICAL PROSTATECTOMY | PREVENTS | SUPPRESSION | DELIVERY | Fibronectins | Impotence
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 06/2011, Volume 163, Issue 3, pp. 567 - 585
Journal Article
by Park, MK and You, HJ and Lee, HJ and Kang, JH and Oh, SH and Kim, SY and Lee, CH
EUROPEAN JOURNAL OF CANCER, ISSN 0959-8049, 05/2013, Volume 49, Issue 7, pp. 1692 - 1705
Epithelial-mesenchymal-transition (EMT) is a key event for tumour cells to initiate metastasis leading to switching of E-cadherin to N-cadherin.... 
SURVIVAL | C-Jun-N-terminal kinase | ADENOCARCINOMA | HUMAN LUNG-CANCER | PP2A | N-cadherin expression | CELL MIGRATION | MODEL | BINDING PROTEIN | INVASION | TGF-beta 1-induced epithelial mesenchymal transition | ONCOLOGY | A549 orthotopic model | DERIVATIVES | Transglutaminase-2
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2012, Volume 49, Issue 7, pp. 1692 - 1705
Journal Article
Molecular Cancer, ISSN 1476-4598, 12/2010, Volume 9, Issue 1, pp. 315 - 315
Background: Perifosine, an alkylphospholipid tested in phase II clinical trials, modulates the extrinsic apoptotic pathway and cooperates with tumor necrosis... 
CARCINOMA-CELLS | DEATH RECEPTORS | SIGNALING PATHWAYS | ONCOLOGY | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALKYL-LYSOPHOSPHOLIPIDS | LEUKEMIA-CELLS | LUNG-CANCER CELLS | ANTITUMOR-ACTIVITY | AKT INHIBITOR PERIFOSINE | RECEPTOR-SELECTIVE RETINOIDS | RADIATION-INDUCED APOPTOSIS | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Glutathione - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Apoptosis - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | Antineoplastic Agents - therapeutic use | Phosphorylcholine - analogs & derivatives | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Head and Neck Neoplasms - metabolism | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Phosphorylcholine - pharmacology | Antineoplastic Agents - pharmacology | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | JNK Mitogen-Activated Protein Kinases - genetics | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Head and Neck Neoplasms - drug therapy | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | Anthracenes - pharmacology | Blotting, Western | Xenograft Model Antitumor Assays | Animals | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Head and Neck Neoplasms - genetics | Mice | RNA, Small Interfering | Phosphorylcholine - therapeutic use | Ligands | Head & neck cancer | Kinases | Manuscripts | Cell cycle | Apoptosis
Journal Article
Journal Article
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 2004, Volume 153, Issue 1, pp. 50 - 63
Bacterial DNA and synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs stimulate the cells of the innate immune system through a specific... 
TLR9 | NF-κB | CpG ODN | Astrocytes | JNK | TRANSCRIPTION FACTORS | CELLS | MOTIFS | PROTEIN-KINASE | IMMUNOLOGY | NEUROSCIENCES | IN-VITRO | NF-kappa B | TOLL-LIKE RECEPTORS | GENE-EXPRESSION | NITRIC-OXIDE | astrocytes | SIGNAL-REGULATED KINASE | BACTERIAL-DNA
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2008, Volume 28, Issue 1, pp. 112 - 120
OBJECTIVE—We evaluated the full range effects of FOXO3a in endothelial cells (ECs) by microarray analysis and investigated the role of FOXO3a regulating TNF... 
NF-κB | FOXO3a | JNK | Apoptosis | FORKHEAD TRANSCRIPTION FACTOR | CELLS | ACTIVATION | PROTEIN-KINASE | apoptosis | SUPPRESSION | FAMILY | NF-kappa B | INHIBITION | PATHWAY | FACTOR FKHR | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY
Journal Article