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Journal Article
Chest, ISSN 0012-3692, 10/2018, Volume 154, Issue 4, pp. 563A - 563A
Journal Article
Cell, ISSN 0092-8674, 04/2018, Volume 173, Issue 3, pp. 665 - 676.e14
Class 2 CRISPR-Cas systems endow microbes with diverse mechanisms for adaptive immunity. Here, we analyzed prokaryotic genome and metagenome sequences to... 
CRISPR | RNA interference | alternative splicing | CasRx | frontotemporal dementia | tau | Cas13 | gene editing | RNA targeting | genome engineering | COMPLEX | ENDONUCLEASE | ALIGNMENT | DNA | PERFORMANCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FRONTOTEMPORAL DEMENTIA | ADAPTATION | SYSTEMS | PROTEINS | CAS IMMUNITY | CELL BIOLOGY | Anopheles | Messenger RNA | Neurons | Analysis | Genes | Genomics | Ribonuclease | Health aspects | Dementia
Journal Article
American Journal of Hematology, ISSN 0361-8609, 11/2018, Volume 93, Issue 11, pp. 1311 - 1317
Duvelisib (IPI‐145) is an oral dual inhibitor of phosphoinositide‐3‐kinase (PI3K)‐δ and ‐γ in clinical development for the treatment of hematologic... 
Journal Article
BLOOD, ISSN 0006-4971, 02/2018, Volume 131, Issue 8, pp. 877 - 887
Duvelisib is an oral dual inhibitor of phosphoinositide 3-kinase-delta (PI3K-delta) and PI3K-gamma in late-stage clinical development for hematologic... 
CYTOKINE PRODUCTION | THERAPY | B-CELL | PI3K | PHOSPHATIDYLINOSITOL 3-KINASE | PHOSPHOINOSITIDE 3-KINASE P110-DELTA | CHRONIC LYMPHOCYTIC-LEUKEMIA | PHASE-II | T-CELL LYMPHOMA | DIFFERENTIATION | HEMATOLOGY | Lymphoid Neoplasia
Journal Article
1986, Monographs in international studies. Southeast Asia series, ISBN 0896801322, Volume no. 72, xiii, 411 p., [16] p. of plates
Book
BLOOD, ISSN 0006-4971, 02/2018, Volume 131, Issue 8, pp. 888 - 898
Duvelisib (IPI-145) is an oral inhibitor of phosphatidylinositol 3-kinase (PI3K)-delta/gamma isoforms currently in clinical development. PI3K-delta/gamma... 
P110-DELTA | MULTICENTER | B-CELL | RESPONSE CRITERIA | IDELALISIB | MACROPHAGES | BRENTUXIMAB VEDOTIN | RESISTANCE | PI3K-GAMMA | HEMATOLOGY | VORINOSTAT | Lymphoid Neoplasia
Journal Article
01/2015
A hallmark of Alzheimer’s disease (AD) is a deteriorated hippocampus; this causes the characteristic pathology of the disease, loss of hippocampal neurons with... 
Neurosciences | Cellular biology | Developmental biology
Dissertation
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 5635 - 5635
Abstract Introduction : Recent studies have shown that leukemic clones in approximately 10-20% of CLL patients have stereotypic IgH gene sequences... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 802 - 802
Abstract Introduction: Signaling via PI3K-δ and PI3K-γ is essential for both normal and malignant B-cell and T-cell proliferation, survival, and migration.... 
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 3335 - 3335
Abstract Introduction: Duvelisib (IPI-145) belongs to an emerging class of therapeutic small molecule kinase inhibitors that target B-cell receptor (BCR)... 
Journal Article
by Blunden, Jessica and Arndt, Derek S and Willett, Kate M and Dolman, A. Johannes and Hurst, Dale F and Rennie, Jared and Thorne, Peter W and Donat, Markus G and Dunn, Robert J. H and Long, Craig S and Christy, John R and Noetzli, Jeannette and Christiansen, Hanne H and Gugliemin, Mauro and Romanovsky, Vladimir E and Shiklomanov, Nicolai I and Smith, Sharon L and Zhao, Lin and Robinson, David A and Pelto, Mauri S and Mears, Carl A and Ho, Shu-Oeng Ben and Peng, Liang and Wang, Junhong and Vose, Russell S and Hilburn, Kyle and Yin, Xungang and Kruk, Michael C and Becker, Andreas and Foster, Michael J and Ackerman, Steven A and Heidinger, Andrew K and Maddux, Brent C and Stengel, M and Kim, Hyuanjun and Oki, Taikan and Rodell, Matthew and Chambers, Don P and Famiglietti, James S and Dorigo, Wouter A and Chung, D and Parinussa, Robert M and Reimer, C and Hahn, S and Liu, Y.Y and Wagner, Wolfgang W and de Jeu, Rochard A. M and Paulik, C and Wang, Guojie and Allan, Rob and Folland, Chris K and Tobin, Isabelle and Berrisford, Paul and Vautard, Robert and McVicar, Tim R and Kratz, David P and Stackhouse, Paul W and Wong, Takmeng and Sawaengphokhai, P and Wilber, Anne C and Gupta, Shashi K and Loeb, Norman G and Lantz, Kathy O and Dlugokencky, Ed J and Hall, Bradley D and Montzka, Stephen A and Dutton, Geoff S and Mühle, Jens and Elkins, James W and Benedetti, Angela and Jones, Luke T and Kaiser, Johannes W and Morcrette, Jean-Jacques and Rémy, Samuel and Weber, Mark and Steinbrecht, Wolfgang and van der A, Ronald J and Coldewey-Egbers, Melanie and Fioletov, Vitali E and Frith, Stacey M and Loyola, Diego and Wild, Jeannette D and Davis, Sean M and Rosenlof, Karen H and Cooper, Owen R and Ziemke, Jerry and Flemming, Johannes and Inness, Antje and Quegan, Shaun and Ciais, Phillipe and Santoro, M and Pinty, Bernard and Gobron, Nadine and van der Werf, Guido R and Newlin, Michele L and Gregg, Margarita C and Xue, Yan and Hu, Zeng-Zhen and Kumar, Arun and Banzon, Viva and ...
Bulletin of the American Meteorological Society, ISSN 0003-0007, 2014, Volume 95, Issue 7, pp. S1 - S279
Journal Article
Journal Article