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PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 4, p. e0175593
Ubiquitin ligase von Hippel-Lindau tumor suppressor (pVHL) negatively regulates protein levels of hypoxia-inducible factor-α (HIF-α). Loss of pVHL causes HIF-α... 
Cell Hypoxia - physiology | Proteasome Inhibitors - pharmacology | Humans | Cell Cycle Proteins - metabolism | Down-Regulation - drug effects | Gene Knockdown Techniques | Cell Nucleus - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Up-Regulation - physiology | HEK293 Cells | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Cell Line, Tumor | Protein Domains | Trans-Activators - metabolism | RNA, Small Interfering | Protein Stability | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Hypoxia-inducible factors | Genetic disorders | Pathogenesis | MYB protein | Homology | Gene expression | Von Hippel-Lindau disease | Proteins | Rodents | Proteasomes | Hypoxia | Tumor suppressor genes | VHL protein | Mutation | Neoplasia | Ubiquitin-protein ligase | Tumors | Avian myeloblastosis | Transcription factors | Downstream effects | Liver | Attachment | Males | Cyclin D1 | Nuclei | Degradation | Angiogenesis | Alterations | Genetics | Inhibition | Vascular endothelial growth factor | Binding | Acinar cells | Splicing | Denaturation | Beta cells | Covalence | Inhibitors | Ribonucleic acids | B-myb gene | Clear cell-type renal cell carcinoma | Kidney transplantation | b-Myb protein | Residues | Genes | Complement | Immunology | Aromatic compounds | Division | Children | Lesions | Alanine | Data processing | Radioactive half-life | Cycloheximide | Lymphocytes B | Females | Cancer
Journal Article
Nature Cell Biology, ISSN 1465-7392, 12/2004, Volume 6, Issue 12, pp. 1229 - 1235
  The cyclin-dependent kinase inhibitor p27(Kip1) is degraded at the G0-G1 transition of the cell cycle by the ubiquitin-proteasome pathway. Although the... 
Physiological aspects | Genetic aspects | Research | Gene expression | Proteolysis | Ligases
Journal Article
Journal Article
Frontiers in Oncology, ISSN 2234-943X, 2012, Volume 2, p. 10
The Elongin complex was originally identified as a positive regulator of RNA polymerase II and is composed of a transcriptionally active subunit (A) and two... 
Ubiquitin | ECS complex | SCF complex | Cullin | Elongin
Journal Article
Animal Science Journal, ISSN 1344-3941, 02/2016, Volume 87, Issue 2, pp. 257 - 265
Journal Article
NATURE CELL BIOLOGY, ISSN 1465-7392, 12/2004, Volume 6, Issue 12, pp. 1229 - 1235
The cyclin-dependent kinase inhibitor p27(Kip1) is degraded at the G0-G1 transition of the cell cycle by the ubiquitin proteasome pathway(1,2). Although the... 
LOCALIZATION | COMPLEX | P27 | PHOSPHORYLATION | KINASE INHIBITOR P27(KIP1) | MEDIATED DEGRADATION | NUCLEAR EXPORT | S-PHASE | SCFSKP2 | PROGRESSION | CELL BIOLOGY | NIH 3T3 Cells | Peptide Hydrolases - genetics | Humans | DNA, Complementary - genetics | Ubiquitin - metabolism | Molecular Sequence Data | Cytoplasm - metabolism | Amino Acid Sequence - genetics | Protein Subunits - metabolism | Protein Subunits - isolation & purification | RNA Interference | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Cytoplasm - genetics | G1 Phase - genetics | Active Transport, Cell Nucleus - genetics | Peptide Hydrolases - metabolism | Protein Subunits - genetics | DNA, Complementary - analysis | Rabbits | Base Sequence - genetics | Tumor Suppressor Proteins - metabolism | Macromolecular Substances - isolation & purification | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Protein Structure, Tertiary - genetics | Receptors, Cytoplasmic and Nuclear - genetics | Mutation - genetics | Down-Regulation - genetics | Cyclin-Dependent Kinase Inhibitor p27 | Animals | Karyopherins - metabolism | Peptide Hydrolases - isolation & purification | Karyopherins - genetics | Ubiquitin-Protein Ligases - isolation & purification | Mice | Ubiquitin-Protein Ligases - genetics | Macromolecular Substances - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
FEBS Letters, ISSN 0014-5793, 05/2018, Volume 592, Issue 10, pp. 1716 - 1724
The ubiquitin‐proteasome system plays a crucial role in cell cycle progression. A previous study suggested that Spo12, a component of the Cdc14 early anaphase... 
Tom1 | proteasome | degradation | mitosis | Spo12 | HECT‐type E3 | HECT-type E3 | CDC14 PHOSPHATASE | ANAPHASE-PROMOTING COMPLEX | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROTEOLYSIS | SACCHAROMYCES-CEREVISIAE | CELL BIOLOGY | BIOPHYSICS | MITOTIC EXIT | CELL-CYCLE | POLO KINASE
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 10/2016, Volume 215, Issue 1, pp. 95 - 95
Proper dynamic regulation of the spindle is essential for successful cell division. However, the molecular mechanisms that regulate spindle dynamics in mitosis... 
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 10/2016, Volume 215, Issue 1, p. 95
  Proper dynamic regulation of the spindle is essential for successful cell division. However, the molecular mechanisms that regulate spindle dynamics in... 
Genotype & phenotype | Cytokines | Cellular biology | Cell division | Genomes | Chromosomes
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 2015, Volume 59, Issue 1, pp. 22 - 34
Despite the crucial role played by the glyoxylate cycle in the virulence of pathogens, seed germination in plants, and sexual development in fungi, we still... 
Journal Article
by Aad, G and Abajyan, T and Abbott, B and Abdallah, J and Abdel Khalek, S and Abdelalim, A.A and Abdinov, O and Aben, R and Abi, B and Abolins, M and AbouZeid, O.S and Abramowicz, H and Abreu, H and Acharya, B.S and Adamczyk, L and Adams, D.L and Addy, T.N and Adelman, J and Adomeit, S and Adragna, P and Adye, T and Aefsky, S and Aguilar-Saavedra, J.A and Agustoni, M and Aharrouche, M and Ahlen, S.P and Ahles, F and Ahmad, A and Ahsan, M and Aielli, G and Akdogan, T and Åkesson, T.P.A and Akimoto, G and Akimov, A.V and Alam, M.A and Alam, M.S and Albert, J and Albrand, S and Aleksa, M and Aleksandrov, I.N and Alessandria, F and Alexa, C and Alexander, G and Alexandre, G and Alexopoulos, T and Alhroob, M and Aliev, M and Alimonti, G and Alison, J and Allbrooke, B.M.M and Allport, P.P and Allwood-Spiers, S.E and Almond, J and Aloisio, A and Alon, R and Alonso, F and Alonso, A and Altheimer, A and Alvarez Gonzalez, B and Alviggi, M.G and Amako, K and Amelung, C and Ammosov, V.V and Amor Dos Santos, S.P and Amorim, A and Amram, N and Anastopoulos, C and Ancu, L.S and Andari, N and Andeen, T and Anders, C.F and Anders, G and Anderson, K.J and Andreazza, A and Andrei, V and Andrieux, M.-L and Anduaga, X.S and Angelidakis, S and Anger, P and Angerami, A and Anghinolfi, F and Anisenkov, A and Anjos, N and Annovi, A and Antonaki, A and Antonelli, M and Antonov, A and Antos, J and Anulli, F and Aoki, M and Aoun, S and Aperio Bella, L and Apolle, R and Arabidze, G and Aracena, I and Arai, Y and Arce, A.T.H and Arfaoui, S and Arguin, J.-F and Arik, M and ... and ATLAS Collaboration and BROOKHAVEN NATIONAL LABORATORY (BNL) and Partikel- och astropartikelfysik and Skolan för teknikvetenskap (SCI) and KTH and Fysik
Physics Letters B, ISSN 0370-2693, 09/2012, Volume 716, Issue 1, pp. 1 - 29
Journal Article