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1. Full Text Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
We identified rare coding variants associated with Alzheimer's disease in a three-stage case-control study of 85,133 subjects. In stage 1, we genotyped 34,174... 
COMMON VARIANTS | IDENTIFIES VARIANTS | METAANALYSIS | GENOTYPE IMPUTATION | LOW-FREQUENCY | SUSCEPTIBILITY | GENETICS & HEREDITY | RISK | LOCI | WAVE2 COMPLEX | GENOME-WIDE ASSOCIATION | Amino Acid Sequence | Microglia - metabolism | Genetic Predisposition to Disease - genetics | Gene Frequency | Humans | Immunity, Innate - genetics | Genotype | Gene Expression Profiling | Case-Control Studies | Linkage Disequilibrium | Membrane Glycoproteins - genetics | Sequence Homology, Amino Acid | Exome - genetics | Protein Interaction Maps - genetics | Adaptor Proteins, Signal Transducing - genetics | Phospholipase C gamma - genetics | Polymorphism, Single Nucleotide | Alzheimer Disease - genetics | Odds Ratio | Receptors, Immunologic - genetics | Immune response | Genetic variation | Physiological aspects | Development and progression | Genetic aspects | Research | Alzheimer's disease | Neurodegenerative diseases | Genes | Genomics | Health risks | Innate immunity | Genomes | Disease control | Immunity | Microglia | Proteins | Immune systems | Studies | Consortia | DNA microarrays | Genotyping | Gene frequency | DNA methylation | Alzheimers disease | Protein interaction | Bioinformatics | Genotypes | Index Medicus | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
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2. Full Text Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A beta, tau, immunity and lipid processing
by Kunkle, BW and Grenier-Boley, B and Sims, R and Bis, JC and Damotte, V and Naj, AC and Boland, A and Vronskaya, M and van der Lee, SJ and Amlie-Wolf, A and Bellenguez, C and Frizatti, A and Chouraki, V and Martin, ER and Sleegers, K and Badarinarayan, N and Jakobsdottir, J and Hamilton-Nelson, KL and Moreno-Grau, S and Olaso, R and Raybould, R and Chen, YN and Kuzma, AB and Hiltunen, M and Morgan, T and Ahmad, S and Vardarajan, BN and Epelbaum, J and Hoffmann, P and Boada, M and Beecham, GW and Garnier, JG and Harold, D and Fitzpatrick, AL and Valladares, O and Moutet, ML and Gerrish, A and Smith, AV and Qu, LM and Bacq, D and Denning, N and Jian, XQ and Zhao, Y and Del Zompo, M and Fox, NC and Choi, SH and Mateo, I and Hughes, JT and Adams, HH and Malamon, J and Sanchez-Garcia, F and Patel, Y and Brody, JA and Dombroski, BA and Naranjo, MCD and Daniilidou, M and Eiriksdottir, G and Mukherjee, S and Wallon, D and Uphill, J and Aspelund, T and Cantwell, LB and Garzia, F and Galimberti, D and Hofer, E and Butkiewicz, M and Fin, B and Scarpini, E and Sarnowski, C and Bush, WS and Meslage, S and Kornhuber, J and White, CC and Song, Y and Barber, RC and Engelborghs, S and Sordon, S and Voijnovic, D and Adams, PM and Vandenberghe, R and Mayhaus, M and Cupples, LA and Albert, MS and De Deyn, PP and Gu, W and Himali, JJ and Beekly, D and Squassina, A and Hartmann, AM and Orellana, A and Blacker, D and Rodriguez-Rodriguez, E and Lovestone, S and Garcia, ME and Doody, RS and Munoz-Fernadez, C and Sussams, R and Lin, HH and Fairchild, TJ and Benito, YA and ... and Cohorts Heart Aging Res Genomic Ep and Alzheimer Dis Genetics Consortium and European Alzheimers Dis Initiative and Genetic Environm Risk AD Defining and Alzheimer Disease Genetics Consortium (ADGC) and Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) and European Alzheimer’s Disease Initiative (EADI) and Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES)
NATURE GENETICS, ISSN 1061-4036, 03/2019, Volume 51, Issue 3, pp. 414 - 414
Risk for late-onset Alzheimer's disease (LOAD), the most prevalent dementia, is partially driven by genetics. To identify LOAD risk loci, we performed a large... 
COMMON VARIANTS | GENOTYPE IMPUTATION | AMYLOID-BETA | GENETICS & HEREDITY | DOMAIN-CONTAINING OXIDOREDUCTASE | MUTATIONS | ANGIOTENSIN-CONVERTING ENZYME | TRANSCRIPTION FACTOR | ONSET | GENOME-WIDE ASSOCIATION | APOLIPOPROTEIN-E | Genetic Predisposition to Disease - genetics | Lipids - genetics | Humans | Genetic Loci - genetics | Male | Genetic Testing - methods | Case-Control Studies | Haplotypes - genetics | tau Proteins - genetics | Amyloid beta-Peptides - genetics | Female | Lipid Metabolism - genetics | Aged | Alzheimer Disease - genetics | Genome-Wide Association Study - methods | Immunity - genetics | Ontology | Genomics | Genes | Lipids | Genomes | Mapping | Family medical history | Immunity | Risk factors | Protein turnover | Datasets | Proteins | Consortia | Genetic analysis | Dementia disorders | Genetics | Lipid metabolism | Alzheimer's disease | Age | ADAMTS-1 protein | Neurodegenerative diseases | Health risks | Metabolism | Risk analysis | Amyloid precursor protein | Meta-analysis | White blood cells | Genetic variance | Tau protein | Histocompatibility antigen HLA | Gene loci | Gene mapping | Alzheimers disease | Secretase | Dementia | Index Medicus
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3. Full Text Systematic analysis of TruSeq, SMARTer and SMARTer Ultra-Low RNA-seq kits for standard, low and ultra-low quantity samples
by Palomares, MA and Dalmasso, C and Bonnet, E and Derbois, C and Brohard-Julien, S and Christopheambroise and Battail, C and Deleuze, JF and Olaso, R
SCIENTIFIC REPORTS, ISSN 2045-2322, 05/2019, Volume 9, Issue 1, pp. 7550 - 12
High-throughput RNA-sequencing has become the gold standard method for whole-transcriptome gene expression analysis, and is widely used in numerous... 
MULTIDISCIPLINARY SCIENCES | REPRODUCIBILITY | Transcription | Gene expression | Therapeutic applications | Life Sciences
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4. Full Text A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families
by Veyssiere, Maëva and Perea, Javier and Michou, Laetitia and Boland, Anne and Caloustian, Christophe and Olaso, Robert and Deleuze, Jean-François and Cornelis, François and Petit-Teixeira, Elisabeth and Chaudru, Valérie
PloS one, ISSN 1932-6203, 2019, Volume 14, Issue 3, pp. e0213387 - e0213387
The triggering and development of Rheumatoid Arthritis (RA) is conditioned by environmental and genetic factors. Despite the identification of more than one... 
Physiological aspects | Genetic aspects | Research | Genetic variation | Rheumatoid arthritis | Risk factors | Rheumatoid factor | Arthritis | Genes | Life Sciences | Genetics | Bioinformatics | Human genetics | Computer Science
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5. Investigation of candidate gene copy number identifies FCGR3B as a potential biomarker for rheumatoid arthritis
by Ben Kilani, Mohamed Sahbi and Cornélis, François and Olaso, Robert and Chaudru, Valerie and Petit-Teixeira, Elisabeth
Clinical and experimental rheumatology, ISSN 0392-856X, 03/2019
Copy number variants (CNVs) could explain a part of the missing heritability in rheumatoid arthritis (RA). Our goal is to investigate the association of RA... 
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6. Full Text Genome-wide nucleosome specificity and function of chromatin remodellers in ES cells
by De Dieuleveult, Maud and Yen, Kuangyu and Hmitou, Isabelle and Depaux, Arnaud and Boussouar, Fayçal and Dargham, Daria Bou and Jounier, Sylvie and Humbertclaude, Hélène and Ribierre, Florence and Baulard, Céline and Farrell, Nina P and Park, Bongsoo and Keime, Céline and Carrière, Lucie and Berlivet, Soizick and Gut, Marta and Gut, Ivo and Werner, Michel and Deleuze, Jean-François and Olaso, Robert and Aude, Jean-Christophe and Chantalat, Sophie and Pugh, B. Franklin and Gérard, Matthieu
Nature, ISSN 0028-0836, 02/2016, Volume 530, Issue 7588, pp. 113 - 116
ATP-dependent chromatin remodellers allow access to DNA for transcription factors and the general transcription machinery, but whether mammalian chromatin... 
PROMOTERS | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | GENES | ARCHITECTURE | TRANSCRIPTION ELONGATION | PLURIPOTENCY | ESBAF | DIFFERENTIATION | CPG ISLANDS | BINDING | Gene Expression Regulation | Genome - genetics | Chromatin Assembly and Disassembly | Nucleosomes - metabolism | Substrate Specificity | Mouse Embryonic Stem Cells - cytology | Nuclear Proteins - metabolism | Nucleosomes - genetics | RNA Polymerase II - metabolism | Promoter Regions, Genetic - genetics | Mouse Embryonic Stem Cells - metabolism | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | DNA Helicases - metabolism | Animals | Micrococcal Nuclease - metabolism | Transcription Initiation Site | Trans-Activators - metabolism | Mice | Histones - metabolism | Chromatin | Genome-wide association studies | Genetic aspects | Research | Embryonic stem cells | Genomes | RNA polymerase | Gene expression | Embryos | Deoxyribonucleic acid--DNA | Cells | Index Medicus | Life Sciences
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7. Full Text Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
by Kunkle, Brian W and Grenier-Boley, Benjamin and Sims, Rebecca and Bis, Joshua C and Damotte, Vincent and Naj, Adam C and Boland, Anne and Vronskaya, Maria and van der Lee, Sven J and Amlie-Wolf, Alexandre and Bellenguez, Céline and Frizatti, Aura and Chouraki, Vincent and Martin, Eden R and Sleegers, Kristel and Badarinarayan, Nandini and Jakobsdottir, Johanna and Hamilton-Nelson, Kara L and Moreno-Grau, Sonia and Olaso, Robert and Raybould, Rachel and Chen, Yuning and Kuzma, Amanda B and Hiltunen, Mikko and Morgan, Taniesha and Ahmad, Shahzad and Vardarajan, Badri N and Epelbaum, Jacques and Hoffmann, Per and Boada, Merce and Beecham, Gary W and Garnier, Jean-Guillaume and Harold, Denise and Fitzpatrick, Annette L and Valladares, Otto and Moutet, Marie-Laure and Gerrish, Amy and Smith, Albert V and Qu, Liming and Bacq, Delphine and Denning, Nicola and Jian, Xueqiu and Zhao, Yi and Del Zompo, Maria and Fox, Nick C and Choi, Seung-Hoan and Mateo, Ignacio and Hughes, Joseph T and Adams, Hieab H and Malamon, John and Sanchez-Garcia, Florentino and Patel, Yogen and Brody, Jennifer A and Dombroski, Beth A and Naranjo, Maria Candida Deniz and Daniilidou, Makrina and Eiriksdottir, Gudny and Mukherjee, Shubhabrata and Wallon, David and Uphill, James and Aspelund, Thor and Cantwell, Laura B and Garzia, Fabienne and Galimberti, Daniela and Hofer, Edith and Butkiewicz, Mariusz and Fin, Bertrand and Scarpini, Elio and Sarnowski, Chloe and Bush, Will S and Meslage, Stéphane and Kornhuber, Johannes and White, Charles C and Song, Yuenjoo and Barber, Robert C and Engelborghs, Sebastiaan and Sordon, Sabrina and Voijnovic, Dina and Adams, Perrie M and Vandenberghe, Rik and Mayhaus, Manuel and Cupples, L Adrienne and Albert, Marilyn S and De Deyn, Peter P and Gu, Wei and Himali, Jayanadra J and Beekly, Duane and Squassina, Alessio and Hartmann, Annette M and Orellana, Adelina and Blacker, Deborah and Rodriguez-Rodriguez, Eloy and Lovestone, Simon and Garcia, Melissa E and Doody, Rachelle S and Munoz-Fernadez, Carmen and Sussams, Rebecca and Lin, Honghuang and Fairchild, Thomas J and Benito, Yolanda A and ... and Alzheimer Disease Genetics Consortium (ADGC) and Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) and European Alzheimer’s Disease Initiative (EADI) and Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES)
Nature genetics, ISSN 1061-4036, 08/2019, Volume 51, Issue 9, pp. 1423 - 1424
An amendment to this paper has been published and can be accessed via a link at the top of the paper. 
Bass | Cranes | Neurodegenerative diseases | Health risks | Risk | Lipids | Epidemiology | Immunity | Environmental risk | Consortia | Tau protein | Genetic analysis | Aging | Liming | Genetics | Error correction | Alzheimers disease | Alzheimer's disease | Index Medicus
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8. Full Text Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
by Kunkle, Brian W and Grenier-Boley, Benjamin and Sims, Rebecca and Bis, Joshua C and Damotte, Vincent and Naj, Adam C and Boland, Anne and Vronskaya, Maria and van der Lee, Sven J and Amlie-Wolf, Alexandre and Bellenguez, Céline and Frizatti, Aura and Chouraki, Vincent and Martin, Eden R and Sleegers, Kristel and Badarinarayan, Nandini and Jakobsdottir, Johanna and Hamilton-Nelson, Kara L and Moreno-Grau, Sonia and Olaso, Robert and Raybould, Rachel and Chen, Yuning and Kuzma, Amanda B and Hiltunen, Mikko and Morgan, Taniesha and Ahmad, Shahzad and Vardarajan, Badri N and Epelbaum, Jacques and Hoffmann, Per and Boada, Merce and Beecham, Gary W and Garnier, Jean-Guillaume and Harold, Denise and Fitzpatrick, Annette L and Valladares, Otto and Moutet, Marie-Laure and Gerrish, Amy and Smith, Albert V and Qu, Liming and Bacq, Delphine and Denning, Nicola and Jian, Xueqiu and Zhao, Yi and Del Zompo, Maria and Fox, Nick C and Choi, Seung-Hoan and Mateo, Ignacio and Hughes, Joseph T and Adams, Hieab H and Malamon, John and Sanchez-Garcia, Florentino and Patel, Yogen and Brody, Jennifer A and Dombroski, Beth A and Naranjo, Maria Candida Deniz and Daniilidou, Makrina and Eiriksdottir, Gudny and Mukherjee, Shubhabrata and Wallon, David and Uphill, James and Aspelund, Thor and Cantwell, Laura B and Garzia, Fabienne and Galimberti, Daniela and Hofer, Edith and Butkiewicz, Mariusz and Fin, Bertrand and Scarpini, Elio and Sarnowski, Chloe and Bush, Will S and Meslage, Stéphane and Kornhuber, Johannes and White, Charles C and Song, Yuenjoo and Barber, Robert C and Engelborghs, Sebastiaan and Sordon, Sabrina and Voijnovic, Dina and Adams, Perrie M and Vandenberghe, Rik and Mayhaus, Manuel and Cupples, L. Adrienne and Albert, Marilyn S and De Deyn, Peter P and Gu, Wei and Himali, Jayanadra J and Beekly, Duane and Squassina, Alessio and Hartmann, Annette M and Orellana, Adelina and Blacker, Deborah and Rodriguez-Rodriguez, Eloy and Lovestone, Simon and Garcia, Melissa E and Doody, Rachelle S and Munoz-Fernadez, Carmen and Sussams, Rebecca and Lin, Honghuang and Fairchild, Thomas J and Benito, Yolanda A and ... and Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE) and Alzheimer Disease Genetics Consortium (ADGC) and The European Alzheimer’s Disease Initiative (EADI) and Genetic and Environmental Risk in AD/Defining Genetic, Polygenic and Environmental Risk for Alzheimer’s Disease Consortium (GERAD/PERADES)
Nature Genetics, ISSN 1061-4036, 03/2019, Volume 51, Issue 3, pp. 414 - 430
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9. Full Text Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
by Sims, Rebecca and van der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and Medicinska fakulteten and Geriatrik and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för folkhälso- och vårdvetenskap
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 9, p. 1373
We identified rare coding variants associated with Alzheimer's disease in a three-stage case-control study of 85,133 subjects. In stage 1, we genotyped 34,174... 
Amino Acid Sequence | Genetic Predisposition to Disease | GERAD/PERADES, CHARGE, ADGC, EADI | ARUK Consortium | Humans | Gene Frequency | Genotype | Gene Expression Profiling | Alzheimer Disease | Immunity, Innate | Case-Control Studies | Microglia | Linkage Disequilibrium | Protein Interaction Maps | Sequence Homology, Amino Acid | Exome | Adaptor Proteins, Signal Transducing | Phospholipase C gamma | Receptors, Immunologic | Polymorphism, Single Nucleotide | Membrane Glycoproteins | Odds Ratio | Genetik | Biological Sciences | Genetics | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
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10. Full Text Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology
by Coudert, Amélie E and Del Fattore, Andrea and Baulard, Céline and Olaso, Robert and Schiltz, Corinne and Collet, Corinne and Teti, Anna and De Vernejoul, Marie-Christine
Laboratory Investigation, ISSN 0023-6837, 03/2014, Volume 94, Issue 3, pp. 275 - 285
Autosomal dominant osteopetrosis type II (ADO II) is a rare, heritable bone disorder characterized by a high bone mass and insufficient osteoclast activity.... 
ADO II | WARS | integrin β5 | SERPINE2 | osteoclasts | MEDICINE, RESEARCH & EXPERIMENTAL | PERFORIN | RECESSIVE OSTEOPETROSIS | DEFICIENT MICE | PATHOLOGY | integrin beta 5 | REQUIRES OSTM1 | BONE-RESORPTION | CLCN7 GENE | ALBERS-SCHONBERG-DISEASE | IN-VITRO | CHLORIDE CHANNEL | MUTATIONS | Pore Forming Cytotoxic Proteins - genetics | Humans | Middle Aged | Transcriptome | Male | Chloride Channels - genetics | Mutation, Missense | RNA, Messenger - metabolism | GTP-Binding Proteins - genetics | Case-Control Studies | Young Adult | Aged, 80 and over | Adult | Female | Carboxylic Ester Hydrolases - genetics | Perforin | Osteopetrosis - genetics | Pore Forming Cytotoxic Proteins - metabolism | RNA, Messenger - genetics | Mutant Proteins - genetics | Mutant Proteins - metabolism | Osteopetrosis - metabolism | Ubiquitin Thiolesterase - genetics | Osteoclasts - metabolism | Tryptophan-tRNA Ligase - genetics | Chloride Channels - metabolism | Tryptophan-tRNA Ligase - metabolism | Phenotype | Serpin E2 - genetics | Integrin beta Chains - metabolism | Aged | Integrin beta Chains - genetics | Mutation | Serpin E2 - metabolism | Index Medicus | Life Sciences | Human health and pathology | Rhumatology and musculoskeletal system | Biochemistry, Molecular Biology | Genomics
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11. Full Text Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression
by Contrepois, Kévin and Coudereau, Clément and Benayoun, Bérénice A and Schuler, Nadine and Roux, Pierre-François and Bischof, Oliver and Courbeyrette, Régis and Carvalho, Cyril and Thuret, Jean-Yves and Ma, Zhihai and Derbois, Céline and Nevers, Marie-Claire and Volland, Hervé and Redon, Christophe E and Bonner, William M and Deleuze, Jean-François and Wiel, Clotilde and Bernard, David and Snyder, Michael P and Rübe, Claudia E and Olaso, Robert and Fenaille, François and Mann, Carl
Nature Communications, ISSN 2041-1723, 2017, Volume 8, Issue 1, pp. 14995 - 14995
The senescence of mammalian cells is characterized by a proliferative arrest in response to stress and the expression of an inflammatory phenotype. Here we... 
SIDE | SECRETORY PHENOTYPE | TUMOR SUPPRESSION | MULTIDISCIPLINARY SCIENCES | MICE | GENOMIC FEATURES | CELLULAR SENESCENCE | CANCER | PROGRAM | Cell Line | Cellular Senescence - genetics | Cell Proliferation - genetics | Age Factors | Cytokines - metabolism | Skin - metabolism | Humans | Mice, Inbred C57BL | Gene Expression Profiling | Genetic Variation | Animals | Histones - genetics | Inflammation Mediators - metabolism | Fibroblasts - cytology | DNA Damage | Histones - metabolism | Cytokines - genetics | Fibroblasts - metabolism | Index Medicus | Life Sciences | Cellular Biology
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