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Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e60658
Recent studies support a role for FGF23 and its co-receptor Klotho in cardiovascular pathology, yet the underlying mechanisms remain largely elusive. Herein,... 
MORTALITY | COMMUNITY | MULTIDISCIPLINARY SCIENCES | RECEPTOR | SMOOTH-MUSCLE-CELLS | FIBROBLAST GROWTH FACTOR-23 | CHRONIC KIDNEY-DISEASE | LEFT-VENTRICULAR HYPERTROPHY | DELETION | Calcinosis - genetics | Muscle, Smooth, Vascular - metabolism | Glucuronidase - metabolism | Male | Arteries - drug effects | Fibroblast Growth Factors - pharmacology | Arteries - pathology | Muscle, Smooth, Vascular - cytology | Glucuronidase - deficiency | Arteries - metabolism | Gene Expression Regulation - drug effects | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Glucuronidase - genetics | Time Factors | Cattle | Arteries - physiopathology | Gene Deletion | Early Growth Response Protein 1 - genetics | Female | Mice | Calcinosis - metabolism | Muscle, Smooth, Vascular - drug effects | Calcification (ectopic) | Immunohistochemistry | Intravenous administration | Fibroblast growth factor 23 | Laboratories | Science | Smooth muscle | Cardiovascular disease | Biochemistry | Cardiovascular pathology | Kinases | Arteries | Proteins | Clonal deletion | Mineralization | Rodents | Deletion | Fibroblasts | Growth factors | Delivery contracts | Kidneys | EGR-1 protein | Mortality | Contractility | Muscles | Metabolism | Muscle contraction | Mineral metabolism | Medicine | Signaling | Klotho protein | Calcification | Kidney diseases | Veins & arteries
Journal Article
FASEB Journal, ISSN 0892-6638, 05/2017, Volume 31, Issue 5, pp. 2050 - 2064
Journal Article
Bone, ISSN 8756-3282, 07/2017, Volume 100, p. 19
[alpha]Klotho (Klotho), a type I transmembrane protein and a coreceptor for Fibroblast Growth Factor-23, was initially thought to be expressed only in a... 
Physiological aspects | Fibroblast growth factors
Journal Article
Journal Article
Kidney International, ISSN 0085-2538, 11/2010, Volume 78, Issue 10, pp. 1024 - 1032
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2016, Volume 126, Issue 5, pp. 1926 - 1938
Journal Article
Journal of the American Society of Nephrology : JASN, ISSN 1046-6673, 10/2014, Volume 25, Issue 10, pp. 2169 - 2175
Klotho was discovered as an antiaging gene, and a-Klotho (Klotho) is expressed in multiple tissues with a broad set of biologic functions. Membrane-bound... 
calcium | mineral metabolism | hyperphosphatemia | vascular calcification | PHOSPHATE | PROTEIN | GENE | METABOLISM | UROLOGY & NEPHROLOGY | TUBULE | FGF-RECEPTOR 1 | MICE | EXPRESSION | Fibroblast Growth Factors - metabolism | Glucuronidase - physiology | Kidney - metabolism | Animals | Kidney - pathology | Female | Male | Aging - metabolism | Mice, Knockout | Brief Communications
Journal Article
PLOS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132353
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 09/2012, Volume 23, Issue 10, pp. 1641 - 1651
Renal Klotho controls mineral metabolism by directly modulating tubular reabsorption of phosphate and calcium and by acting as a co-receptor for the... 
PHOSPHATE | MORTALITY | HOMEOSTASIS | FIBROBLAST-GROWTH-FACTOR-23 | UROLOGY & NEPHROLOGY | PARATHYROID-HORMONE | ABLATION | MICE | FIBROBLAST GROWTH FACTOR-23 | EXPRESSION | FGF RECEPTOR | Gene Targeting | Gene Expression | Signal Transduction | Calcium - metabolism | Glucuronidase - metabolism | Homeostasis | Hyperphosphatemia - metabolism | Male