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1. Full Text Optimal treatment strategies for hemophilia: Achievements and limitations of current prophylactic regimens
by Oldenburg, Johannes
Blood, ISSN 0006-4971, 03/2015, Volume 125, Issue 13, pp. 2038 - 2044
Life Sciences & Biomedicine | Hematology | Science & Technology | Hemarthrosis - diagnosis | Ankle Joint - pathology | Prognosis | Age Factors | Primary Prevention - standards | Humans | Treatment Outcome | Hemophilia A - therapy | Hemophilia A - complications | Blood Coagulation Factors - therapeutic use | Primary Prevention - methods | Adult | Hemarthrosis - prevention & control | Hemophilia A - diagnosis | Child | Index Medicus | Abridged Index Medicus
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2. Full Text Structure functional insights into calcium binding during the activation of coagulation factor XIII A
by Singh, Sneha and Dodt, Johannes and Volkers, Peter and Hethershaw, Emma and Philippou, Helen and Ivaskevicius, Vytautus and Imhof, Diana and Oldenburg, Johannes and Biswas, Arijit
Scientific reports, ISSN 2045-2322, 08/2019, Volume 9, Issue 1, pp. 11324 - 18
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Coagulation factor XIII | Coagulation factors | Solvents | Fibrin | Calcium-binding protein | Coagulation | Thrombin | Fibrinolysis | Binding sites | Index Medicus
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3. Full Text Defining Severity of Hemophilia: More than Factor Levels
by Pavlova, Anna and Oldenburg, Johannes
Seminars in thrombosis and hemostasis, ISSN 0094-6176, 10/2013, Volume 39, Issue 7, pp. 702 - 710
phenotype heterogeneity | hemophilia | factor FVIII/IX levels | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Severity of Illness Index | Hemophilia B - pathology | Humans | Hemophilia B - blood | Factor VIII - genetics | Factor IX - genetics | Factor IX - metabolism | Hemophilia A - genetics | Factor VIII - metabolism | Hemophilia B - genetics | Hemophilia A - blood | Hemophilia A - pathology | Index Medicus
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4. Full Text Identification of Potential Novel Interacting Partners for Coagulation Factor XIII B (FXIII-B) Subunit, a Protein Associated with a Rare Bleeding Disorder
by Singh, Sneha and Akhter, Mohammad Suhail and Dodt, Johannes and Volkers, Peter and Reuter, Andreas and Reinhart, Christoph and Krettler, Christoph and Oldenburg, Johannes and Biswas, Arijit
International journal of molecular sciences, ISSN 1422-0067, 06/2019, Volume 20, Issue 11, p. 2682
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Coagulation factor XIII | Plasma | a2-Macroglobulin | Excipients | Protein purification | Coagulation | Mass spectroscopy | Crosslinking | Complement | Fibrinolysis | Bleeding | Proteins | Coagulation factors | Complement component C1q | Fibrin | Complement factor H | Complement component C3 | Physiology | Catalysis | Mass spectrometry | Index Medicus | mass spectrometry | FXIII deficiency | excipients | pleiotropy | Factor XIII | complement system
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5. Full Text Open discussion following presentation by Dr \Johannes Oldenburg
by Oldenburg, Johannes
Haemophilia : the official journal of the World Federation of Hemophilia, ISSN 1351-8216, 12/2006, Volume 12, pp. 22 - 22
Life Sciences & Biomedicine | Hematology | Science & Technology
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6. Full Text Disruption of Structural Disulfides of Coagulation FXIII-B Subunit; Functional Implications for a Rare Bleeding Disorder
by Singh, Sneha and Akhter, Mohammad Suhail and Dodt, Johannes and Sharma, Amit and Kaniyappan, Senthilvelrajan and Yadegari, Hamideh and Ivaskevicius, Vytautas and Oldenburg, Johannes and Biswas, Arijit
International journal of molecular sciences, ISSN 1422-0067, 04/2019, Volume 20, Issue 8, p. 1956
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Cysteine | Alanine | Peptides | Genes | Free form | Coagulation | Bleeding | Mutants | Proteins | Substitutes | Studies | Fibrin | Microscopy | Protein folding | Chemical bonds | Mutation | Disruption | disulfide bonds | FXIII-B | coagulation Factor XIII | FXIII deficiency
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7. Full Text Emicizumab Prophylaxis in Hemophilia A with Inhibitors
by Oldenburg, Johannes and Mahlangu, Johnny N and Kim, Benjamin and Schmitt, Christophe and Callaghan, Michael U and Young, Guy and Santagostino, Elena and Kruse-Jarres, Rebecca and Negrier, Claude and Kessler, Craig and Valente, Nancy and Asikanius, Elina and Levy, Gallia G and Windyga, Jerzy and Shima, Midori
The New England journal of medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 9, pp. 809 - 818
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Recombinant Proteins - therapeutic use | Factor VIII - immunology | Thrombosis - chemically induced | Humans | Middle Aged | Antibodies, Bispecific - pharmacokinetics | Male | Hemorrhage - prevention & control | Factor VIIa - therapeutic use | Isoantibodies - blood | Young Adult | Antibodies, Monoclonal, Humanized - pharmacokinetics | Injections, Subcutaneous | Adult | Drug Therapy, Combination | Child | Factor VIII - therapeutic use | Antibodies, Monoclonal, Humanized - adverse effects | Antibodies, Monoclonal, Humanized - therapeutic use | Hemophilia A - immunology | Antibodies, Bispecific - therapeutic use | Antibodies, Bispecific - adverse effects | Blood Coagulation Factors - adverse effects | Adolescent | Blood Coagulation Factors - therapeutic use | Aged | Hemophilia A - drug therapy | Care and treatment | Hemorrhage | Analysis | Hemophilia | Thrombotic microangiopathy | Hematology | Prophylaxis | Antibodies | Recovery of function | Thrombosis | Bleeding | Medicine | Coagulation factors | Prothrombin | Drug dosages | Index Medicus | Abridged Index Medicus
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8. Full Text Coagulation Factor XIIIA Subunit Missense Mutations Affect Structure and Function at the Various Steps of Factor XIII Action
by Thomas, Anne and Biswas, Arijit and Dodt, Johannes and Philippou, Helen and Hethershaw, Emma and Ensikat, Hans Juergen and Ivaskevicius, Vytautas and Oldenburg, Johannes
Human mutation, ISSN 1059-7794, 10/2016, Volume 37, Issue 10, pp. 1030 - 1041
in silico structural analysis | F13A1 | F13B | expression analysis | Factor XIII(FXIII)deficiency | molecular basis of inherited coagulopathies | Molecular basis of inherited coagulopathies | Expression analysis | In silico structural analysis | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Factor XIIIa - chemistry | Humans | Cells, Cultured | Models, Molecular | Mutation, Missense | Factor XIIIa - metabolism | Protein Subunits - metabolism | Factor XIIIa - genetics | Phenotype | Computer Simulation | Fibrinogen - metabolism | Protein Binding | Molecular Docking Simulation | Thrombin - metabolism | Binding Sites | Factor XIII Deficiency - genetics | alpha-2-Antiplasmin - metabolism | Protein Subunits - genetics | Glycine | Analysis | Glutamine | Proteins | Genotype & phenotype | Mutation | Coagulation | Index Medicus
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9. Full Text Earlier discontinuation of TNF-α inhibitor therapy in female patients with inflammatory bowel disease is related to a greater risk of side effects
by Schultheiss, Johannes P D and Brand, Eelco C and Lamers, Evert and van den Berg, Willemijn C M and van Schaik, Fiona D M and Oldenburg, Bas and Fidder, Herma H
Alimentary pharmacology & therapeutics, ISSN 0269-2813, 08/2019, Volume 50, Issue 4, pp. 386 - 396
Pharmacology (medical) | Hepatology | Journal Article | Gastroenterology | Gastroenterology & Hepatology | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Science & Technology | Medication Adherence - statistics & numerical data | Humans | Antibodies, Monoclonal - therapeutic use | Male | Withholding Treatment - statistics & numerical data | Young Adult | Time Factors | Arthritis, Rheumatoid - drug therapy | Adult | Female | Retrospective Studies | Inflammatory Bowel Diseases - drug therapy | Psoriasis - drug therapy | Drug Administration Schedule | Risk Factors | Arthritis, Rheumatoid - epidemiology | Immunologic Factors - administration & dosage | Drug-Related Side Effects and Adverse Reactions - etiology | Drug-Related Side Effects and Adverse Reactions - epidemiology | Immunotherapy - adverse effects | Psoriasis - epidemiology | Adalimumab - therapeutic use | Adolescent | Immunologic Factors - adverse effects | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Cohort Studies | Therapy | Inflammatory bowel diseases | Physicians | Sex | Arthritis | Males | Confidence intervals | Regression models | Intestine | Tumor necrosis factor-TNF | Drug dosages | Statistical analysis | Psoriasis | Decision making | Regression analysis | Patients | Inflammatory bowel disease | Sex ratio | Side effects | Inhibitors | Tumor necrosis factor | Rheumatoid arthritis | Health hazards | Monoclonal antibodies | Females | Tumors | Index Medicus
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10. Full Text Prophylaxis in bleeding disorders
by Oldenburg, Johannes
Thrombosis research, ISSN 0049-3848, 2010, Volume 127, Issue 1, pp. S14 - S17
Hematology, Oncology and Palliative Medicine | von Willebrand disease | Hemorrhagic disorders | Hemophilia | Prophylaxis | Factor VIII | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Coagulants - therapeutic use | Hemorrhagic Disorders - prevention & control | von Willebrand Diseases - prevention & control | Humans | Blood Coagulation Factors - therapeutic use | Adult | Clinical Trials as Topic | Hemophilia A - prevention & control | Child | Index Medicus
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11. The Current Understanding of Molecular Pathogenesis of Quantitative von Willebrand Disease, Types 1 and 3
by Yadegari, Hamideh and Oldenburg, Johannes
Hämostaseologie, ISSN 0720-9355, 02/2020, Volume 40, Issue 1, pp. 105 - 118
Life Sciences & Biomedicine | Hematology | Science & Technology
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