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1. Full Text Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
by Voight, Benjamin F, PhD and Peloso, Gina M, PhD and Orho-Melander, Marju, PhD and Frikke-Schmidt, Ruth, DMSc and Barbalic, Maja, PhD and Jensen, Majken K, PhD and Hindy, George, MD and Hólm, Hilma, MD and Ding, Eric L, ScD and Johnson, Toby, PhD and Schunkert, Heribert, Prof and Samani, Nilesh J, Prof and Clarke, Robert, MD and Hopewell, Jemma C, PhD and Thompson, John F, Prof and Li, Mingyao, PhD and Thorleifsson, Gudmar, PhD and Newton-Cheh, Christopher, MD and Musunuru, Kiran, MD and Pirruccello, James P, BS and Saleheen, Danish, MBBS and Chen, Li, MSc and Stewart, Alexandre FR, PhD and Schillert, Arne, PhD and Thorsteinsdottir, Unnur, PhD and Thorgeirsson, Gudmundur, MD and Anand, Sonia, Prof and Engert, James C, PhD and Morgan, Thomas, MD and Spertus, John, Prof and Stoll, Monika, Prof and Berger, Klaus, Prof and Martinelli, Nicola, MD and Girelli, Domenico, Prof and McKeown, Pascal P, Prof and Patterson, Christopher C, PhD and Epstein, Stephen E, MD and Devaney, Joseph, PhD and Burnett, Mary-Susan, PhD and Mooser, Vincent, MD and Ripatti, Samuli, PhD and Surakka, Ida, BSci and Nieminen, Markku S, Prof and Sinisalo, Juha, MD and Lokki, Marja-Liisa, PhD and Perola, Markus, Prof and Havulinna, Aki, PhD and de Faire, Ulf, Prof and Gigante, Bruna, MD and Ingelsson, Erik, PhD and Zeller, Tanja, PhD and Wild, Philipp, MD and de Bakker, Paul I W, Prof and Klungel, Olaf H, PhD and Maitland-van der Zee, Anke-Hilse, PhD and Peters, Bas J M, PhD and de Boer, Anthonius, Prof and Grobbee, Diederick E, Prof and Kamphuisen, Pieter W, PhD and Deneer, Vera H M, PhD and Elbers, Clara C, PhD and Onland-Moret, N Charlotte, PhD and Hofker, Marten H, Prof and Wijmenga, Cisca, Prof and Verschuren, WM Monique, PhD and Boer, Jolanda MA, PhD and van der Schouw, Yvonne T, Prof and Rasheed, Asif and Frossard, Philippe and Demissie, Serkalem, PhD and Willer, Cristen, PhD and Do, Ron, PhD and Ordovas, Jose M, Prof and Abecasis, Gonçalo R, Prof and Boehnke, Michael, Prof and Mohlke, Karen L, PhD and Daly, Mark J, PhD and Guiducci, Candace, BS and Burtt, Noël P, BS and Surti, Aarti, BS and Gonzalez, Elena, BS and Purcell, Shaun, PhD and Gabriel, Stacey, PhD and Marrugat, Jaume, PhD and Peden, John, PhD and Erdmann, Jeanette, PhD and Diemert, Patrick, MD and Willenborg, Christina, MSc and König, Inke R, PhD and Fischer, Marcus, MD and Hengstenberg, Christian, MD and Ziegler, Andreas, PhD and Buysschaert, Ian, MD and Lambrechts, Diether, PhD and Van de Werf, Frans, Prof and Fox, Keith A, Prof and El Mokhtari, Nour Eddine, MD and Rubin, Diana, MD and Schrezenmeir, Jürgen, PhD and Schreiber, Stefan, Prof and ...
Lancet, The, ISSN 0140-6736, 08/2012, Volume 380, Issue 9841, pp. 572 - 580
Summary Background High plasma HDL cholesterol is associated with reduced risk of myocardial infarction, but whether this association is causal is unclear.... 
Internal Medicine | ENDOTHELIAL LIPASE | MEDICINE, GENERAL & INTERNAL | METAANALYSIS | BLOOD CHOLESTEROL | ATHEROSCLEROSIS | GENETIC-VARIANTS | LOCI | CORONARY-HEART-DISEASE | HIGH-DENSITY-LIPOPROTEIN | ISCHEMIC CARDIOVASCULAR-DISEASE | ARTERY-DISEASE | Mendelian Randomization Analysis - methods | Myocardial Infarction - blood | Myocardial Infarction - genetics | Genetic Predisposition to Disease | Myocardial Infarction - epidemiology | Prospective Studies | Gene Frequency | Humans | Risk Factors | Biomarkers - blood | Case-Control Studies | Cholesterol, HDL - blood | Cholesterol, LDL - blood | Polymorphism, Single Nucleotide | Myocardial Infarction - etiology | Lipase - genetics | Genetic aspects | High density lipoproteins | Health aspects | Heart attack | Risk factors | Studies | Plasma | Heart attacks | Diet | Cardiovascular disease | Lipids | Cholesterol | Index Medicus | Abridged Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap
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2. Full Text HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
by Swerdlow, Daniel I, Dr and Preiss, David, Dr and Kuchenbaecker, Karoline B, MSc and Holmes, Michael V, PhD and Engmann, Jorgen E L, MSc and Shah, Tina, PhD and Sofat, Reecha, MD and Stender, Stefan, MD and Johnson, Paul C D, PhD and Scott, Robert A, PhD and Leusink, Maarten, MSc and Verweij, Niek, MD and Sharp, Stephen J, MSc and Guo, Yiran, PhD and Giambartolomei, Claudia, MSc and Chung, Christina, MSc and Peasey, Anne, PhD and Amuzu, Antoinette, MSc and Li, KaWah, MSc and Palmen, Jutta, MSc and Howard, Philip, MSc and Cooper, Jackie A, MSc and Drenos, Fotios, PhD and Li, Yun R, BSc and Lowe, Gordon, Prof and Gallacher, John, PhD and Stewart, Marlene C W, PhD and Tzoulaki, Ioanna, PhD and Buxbaum, Sarah G, PhD and van der A, Daphne L, PhD and Forouhi, Nita G, MRCP and Onland-Moret, N Charlotte, PhD and van der Schouw, Yvonne T, Prof and Schnabel, Renate B, MD and Hubacek, Jaroslav A, PhD and Kubinova, Ruzena, MD and Baceviciene, Migle, MD and Tamosiunas, Abdonas, Prof and Pajak, Andrzej, Prof and Topor-Madry, Romanvan, MD and Stepaniak, Urszula, PhD and Malyutina, Sofia, Prof and Baldassarre, Damiano, PhD and Sennblad, Bengt, PhD and Tremoli, Elena, Prof and de Faire, Ulf, Prof and Veglia, Fabrizio, PhD and Ford, Ian, Prof and Jukema, J Wouter, Prof and Westendorp, Rudi G J, Prof and de Borst, Gert Jan, MD and de Jong, Pim A, MD and Algra, Ale, Prof and Spiering, Wilko, MD and der Zee, Anke H Maitland-van, PhD and Klungel, Olaf H, PharmD and de Boer, Anthonius, Prof and Doevendans, Pieter A, Prof and Eaton, Charles B, Prof and Robinson, Jennifer G, Prof and Duggan, David, PhD and Kjekshus, John, Prof and Downs, John R, MD and Gotto, Antonio M, MD and Keech, Anthony C, MD and Marchioli, Roberto, MD and Tognoni, Gianni, MD and Sever, Peter S, Prof and Poulter, Neil R, Prof and Waters, David D, MD and Pedersen, Terje R, MD and Amarenco, Pierre, MD and Nakamura, Haruo, MD and McMurray, John J V, Prof and Lewsey, James D, PhD and Chasman, Daniel I, PhD and Ridker, Paul M, MD and Maggioni, Aldo P, Prof and Tavazzi, Luigi, Prof and Ray, Kausik K, Prof and Seshasai, Sreenivasa Rao Kondapally, MD and Manson, JoAnn E, Prof and Price, Jackie F, MD and Whincup, Peter H, Prof and Morris, Richard W, Prof and Lawlor, Debbie A, Prof and Smith, George Davey, Prof and Ben-Shlomo, Yoav, Prof and Schreiner, Pamela J, Prof and Fornage, Myriam, Prof and Siscovick, David S, Prof and Cushman, Mary, MD and Kumari, Meena, PhD and Wareham, Nick J, Prof and Verschuren, W M Monique, PhD and Redline, Susan, Prof and Patel, Sanjay R, MD and Whittaker, John C, Prof and Hamsten, Anders, Prof and Delaney, Joseph A, PhD and ... and MAGIC Consortium and InterAct Consortium and DIAGRAM Consortium
The Lancet, ISSN 0140-6736, 01/2015, Volume 385, Issue 9965, pp. 351 - 361
Summary Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of... 
Internal Medicine | LDL CHOLESTEROL | MEDICINE, GENERAL & INTERNAL | HIGH-DOSE ATORVASTATIN | METAANALYSIS | STATIN THERAPY | ASSOCIATION ANALYSES | DISEASE | PREVENTION | BODY-MASS INDEX | RISK | MENDELIAN RANDOMIZATION | Body Mass Index | Genetic Testing | Cholesterol, HDL - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Risk Factors | Male | Body Weight - genetics | Randomized Controlled Trials as Topic | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Cholesterol, LDL - metabolism | Polymorphism, Single Nucleotide - genetics | Female | Aged | Hydroxymethylglutaryl CoA Reductases - genetics | Type 2 diabetes | Genetic research | Enzymes | Thiols | Diabetes | Low density lipoprotein | Statins | Cholesterol | Risk factors | Index Medicus | Abridged Index Medicus
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3. Full Text PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study
by Schmidt, Amand F, Dr and Swerdlow, Daniel I, PhD and Holmes, Michael V, PhD and Patel, Riyaz S, MD and Fairhurst-Hunter, Zammy, MSc and Lyall, Donald M, PhD and Hartwig, Fernando Pires, MSc and Horta, Bernardo Lessa, Prof and Hyppönen, Elina, Prof and Power, Christine, Prof and Moldovan, Max, PhD and van Iperen, Erik, MSc and Hovingh, G Kees, Prof and Demuth, Ilja, PhD and Norman, Kristina, PhD and Steinhagen-Thiessen, Elisabeth, Prof and Demuth, Juri, PhD and Bertram, Lars, Prof and Liu, Tian, PhD and Coassin, Stefan, PhD and Willeit, Johann, Prof and Kiechl, Stefan, MD and Willeit, Karin, MD and Mason, Dan, PhD and Wright, John, Prof and Morris, Richard, Prof and Wanamethee, Goya, Prof and Whincup, Peter, Prof and Ben-Shlomo, Yoav, Prof and McLachlan, Stela, PhD and Price, Jackie F, Prof and Kivimaki, Mika, Prof and Welch, Catherine, PhD and Sanchez-Galvez, Adelaida, PhD and Marques-Vidal, Pedro, PhD and Nicolaides, Andrew, PhD and Panayiotou, Andrie G, PhD and Onland-Moret, N Charlotte, PhD and van der Schouw, Yvonne T, Prof and Matullo, Giuseppe, PhD and Fiorito, Giovanni, PhD and Guarrera, Simonetta, MSc and Sacerdote, Carlotta, PhD and Wareham, Nicholas J, Prof and Langenberg, Claudia, PhD and Scott, Robert, PhD and Luan, Jian'an, PhD and Bobak, Martin, Prof and Malyutina, Sofia, Prof and Pająk, Andrzej, PhD and Kubinova, Ruzena, PhD and Tamosiunas, Abdonas, Prof and Pikhart, Hynek, PhD and Husemoen, Lise Lotte Nystrup, PhD and Grarup, Niels, PhD and Pedersen, Oluf, PhD and Hansen, Torben, PhD and Linneberg, Allan, Prof and Simonsen, Kenneth Starup, PhD and Cooper, Jackie, MSc and Humphries, Steve E, Prof and Brilliant, Murray, PhD and Kitchner, Terrie, CCRP and Hakonarson, Hakon, PhD and Carrell, David S, PhD and McCarty, Catherine A, PhD and Kirchner, H Lester, PhD and Larson, Eric B, MD and Crosslin, David R, PhD and de Andrade, Mariza, Prof and Roden, Dan M, Prof and Denny, Joshua C, MD and Carty, Cara, PhD and Hancock, Stephen, MSciStud and Attia, John, PhD and Holliday, Elizabeth, PhD and O'Donnell, Martin, PhD and Yusuf, Salim, Prof and Chong, Michael, MSc and Pare, Guillaume, Prof and van der Harst, Pim, Prof and Said, M Abdullah, BSc and Eppinga, Ruben N, PhD and Verweij, Niek, PhD and Snieder, Harold, Prof and Christen, Tim, MSc and Mook-Kanamori, Dennis O, PhD and Gustafsson, Stefan, PhD and Lind, Lars, Prof and Ingelsson, Erik, Prof and Pazoki, Raha, PhD and Franco, Oscar, PhD and Hofman, Albert, Prof and Uitterlinden, Andre, PhD and Dehghan, Abbas, PhD and Teumer, Alexander, PhD and Baumeister, Sebastian, PhD and Dörr, Marcus, Prof and Lerch, Markus M, Prof and Völker, Uwe, Prof and ... and UCLEB Consortium and LifeLines Cohort Study Grp and UCLEB consortium and LifeLines Cohort study group and Medicinska fakulteten and Science for Life Laboratory, SciLifeLab and Medicinska och farmaceutiska vetenskapsområdet and Uppsala universitet and Institutionen för medicinska vetenskaper and Molekylär epidemiologi
Lancet Diabetes & Endocrinology, The, ISSN 2213-8587, 2017, Volume 5, Issue 2, pp. 97 - 105
Summary Background Statin treatment and variants in the gene encoding HMG-CoA reductase are associated with reductions in both the concentration of LDL... 
Endocrinology & Metabolism | Other | STATIN THERAPY | LDL | DISEASE | ENDOCRINOLOGY & METABOLISM | ARCHITECTURE | COMMON | HYPERCHOLESTEROLEMIA | ASSOCIATION | INSIGHTS | Mendelian Randomization Analysis - methods | Genetic Predisposition to Disease - genetics | Randomized Controlled Trials as Topic - methods | Diabetes Mellitus, Type 2 - genetics | Humans | Proprotein Convertase 9 - genetics | Case-Control Studies | Cholesterol, LDL - genetics | Diabetes Mellitus, Type 2 - diagnosis | Diabetes Mellitus, Type 2 - blood | Cholesterol, LDL - blood | Genetic Variation - genetics | Blood Glucose - metabolism | Cohort Studies | Type 2 diabetes | Genetic variation | Analysis | Body weight | Dosage and administration | Risk factors | Statins | Index Medicus | Life Sciences | Clinical Medicine | Medical and Health Sciences | Endokrinologi och diabetes | Klinisk medicin | Medicin och hälsovetenskap | Endocrinology and Diabetes
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4. Full Text Cystatin C and Cardiovascular Disease
by van der Laan, Sander W., MSc and Fall, Tove, PhD and Soumaré, Aicha, PhD and Teumer, Alexander, PhD and Sedaghat, Sanaz, MSc and Baumert, Jens, PhD and Zabaneh, Delilah, PhD and van Setten, Jessica, PhD and Isgum, Ivana, PhD and Galesloot, Tessel E., PhD and Arpegård, Johannes, MD and Amouyel, Philippe, MD, PhD and Trompet, Stella, PhD and Waldenberger, Melanie, PhD, MPH and Dörr, Marcus, MD and Magnusson, Patrik K., PhD and Giedraitis, Vilmantas, PhD and Larsson, Anders, MD, PhD and Morris, Andrew P., PhD and Felix, Janine F., PhD and Morrison, Alanna C., PhD and Franceschini, Nora, MD, MPH and Bis, Joshua C., PhD and Kavousi, Maryam, MD, PhD and O'Donnell, Christopher, MD, MPH and Drenos, Fotios, PhD and Tragante, Vinicius, PhD and Munroe, Patricia B., PhD and Malik, Rainer, PhD and Dichgans, Martin, MD, PhD and Worrall, Bradford B., MD, PhD and Erdmann, Jeanette, PhD and Nelson, Christopher P., PhD and Samani, Nilesh J., PhD and Schunkert, Heribert, MD, PhD and Marchini, Jonathan, PhD and Patel, Riyaz S., MD, PhD and Hingorani, Aroon D., MD, PhD and Lind, Lars, MD, PhD and Pedersen, Nancy L., PhD and de Graaf, Jacqueline, MD, PhD and Kiemeney, Lambertus A.L.M., PhD and Baumeister, Sebastian E., PhD and Franco, Oscar H., MD, PhD and Hofman, Albert, MD, PhD and Uitterlinden, André G., PhD and Koenig, Wolfgang, MD, PhD and Meisinger, Christa, MD, MPH and Peters, Annette, PhD, MSc and Thorand, Barbara, PhD, MPH and Jukema, J. Wouter, MD, PhD and Eriksen, Bjørn Odvar, MD, PhD and Toft, Ingrid, MD, PhD and Wilsgaard, Tom, PhD and Onland-Moret, N. Charlotte, PhD and van der Schouw, Yvonne T., PhD and Debette, Stéphanie, MD, PhD and Kumari, Meena, PhD and Svensson, Per, MD, PhD and van der Harst, Pim, MD, PhD and Kivimaki, Mika, MD, MA and Keating, Brendan J., PhD and Sattar, Naveed, MD, PhD and Dehghan, Abbas, MD, PhD and Reiner, Alex P., MD, MSc and Ingelsson, Erik, MD, PhD and den Ruijter, Hester M., PhD and de Bakker, Paul I.W., PhD and Pasterkamp, Gerard, MD, PhD and Ärnlöv, Johan, PhD and Holmes, Michael V., MD, PhD and Asselbergs, Folkert W., MD, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2016, Volume 68, Issue 9, pp. 934 - 945
Abstract Background Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD), independent of... 
Cardiovascular | Internal Medicine | heart failure | coronary heart disease | genetics | ischemic stroke | Cardiovascular diseases
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5. Full Text Alcohol drinking and endometrial cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study
by Fedirko, Veronika, PhD and Jenab, Mazda, PhD and Rinaldi, Sabina, PhD and Biessy, Carine, MSc and Allen, Naomi E., PhD and Dossus, Laure, PhD and Onland-Moret, N. Charlotte, PhD and Schütze, Madlen, PhD and Tjønneland, Anne, MD, PhD and Hansen, Louise, MSc and Overvad, Kim, PhD and Clavel-Chapelon, Françoise, PhD and Chabbert-Buffet, Nathalie, MD, PhD and Kaaks, Rudolf, PhD and Lukanova, Annekatrin, PhD and Bergmann, Manuela M., PhD and Boeing, Heiner, PhD and Trichopoulou, Antonia, MD, PhD and Oustoglou, Erifili, MD and Barbitsioti, Antonia, MD and Saieva, Calogero, MD and Tagliabue, Giovanna, MD and Galasso, Rocco, MD and Tumino, Rosario, MD and Sacerdote, Carlotta, MD, PhD and Peeters, Petra H., MD, PhD and Bueno-de-Mesquita, H. Bas, MD, PhD and Weiderpass, Elisabete, MD, PhD and Gram, Inger Torhild, MD, PhD and Sanchez, Soledad, RN and Duell, Eric J., PhD and Molina-Montes, Esther, PhD and Arriola, Larraitz, MD and Chirlaque, Maria-Dolores, MD and Ardanaz, Eva, MD, PhD and Manjer, Jonas, MD, PhD and Lundin, Eva, MD, PhD and Idahl, Annika, MD, PhD and Khaw, Kay-Tee, MBBChir and Romaguera-Bosch, Dora, PhD and Wark, Petra A., PhD and Norat, Teresa, PhD and Romieu, Isabelle, MD, PhD and Medicinska fakulteten and Institutionen för klinisk vetenskap and Patologi and Obstetrik och gynekologi and Institutionen för medicinsk biovetenskap and Umeå universitet
Annals of Epidemiology, ISSN 1047-2797, 2013, Volume 23, Issue 2, pp. 93 - 98
Abstract Purpose Alcohol intake may adversely affect the concentrations of endogenous sex hormones, and thus increase the risk of endometrial cancer. However,... 
Internal Medicine | Ethanol | Endometrial neoplasms | Cohort studies | Western Europe | PREMENOPAUSAL WOMEN | INSULIN SENSITIVITY | INFLAMMATORY MARKERS | PROSPECTIVE COHORT | CIGARETTE-SMOKING | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | SYSTEMIC MARKERS | HORMONE CONCENTRATIONS | ESTRADIOL LEVELS | POSTMENOPAUSAL WOMEN | GROWTH-FACTOR-I | Confidence Intervals | Life Style | Prospective Studies | Humans | Middle Aged | Risk Factors | Endometrial Neoplasms - etiology | Proportional Hazards Models | Europe - epidemiology | Endometrial Neoplasms - epidemiology | Alcohol Drinking - adverse effects | Alcoholic Beverages - adverse effects | Socioeconomic Factors | Incidence | Alcohol Drinking - epidemiology | Adult | Female | Surveys and Questionnaires | Aged | Odds Ratio | Medical colleges | Endometrial cancer | Oncology, Experimental | Drinking of alcoholic beverages | Research | Risk factors | Biometry | Prevention | Hormones, Sex | Health aspects | Histochemistry | Public health | Cancer | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap
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6. Full Text Secretory Phospholipase A2 -IIA and Cardiovascular Disease
by Holmes, Michael V., MSc and Simon, Tabassome, MD, PhD and Exeter, Holly J., PhD and Folkersen, Lasse, PhD and Asselbergs, Folkert W., MD, PhD and Guardiola, Montse, PhD and Cooper, Jackie A., MSc and Palmen, Jutta, MSc and Hubacek, Jaroslav A., DSc, PhD and Carruthers, Kathryn F., MPhil and Horne, Benjamin D., PhD, MPH and Brunisholz, Kimberly D., MST and Mega, Jessica L., MD, MPH and van Iperen, Erik P.A., MSc and Li, Mingyao, PhD and Leusink, Maarten, MSc and Trompet, Stella, PhD and Verschuren, Jeffrey J.W., MD, MSc and Hovingh, G. Kees, MD, PhD and Dehghan, Abbas, MD, PhD and Nelson, Christopher P., PhD and Kotti, Salma, PharmD, PhD and Danchin, Nicolas, MD, PhD and Scholz, Markus, PhD and Haase, Christiane L., PhD and Rothenbacher, Dietrich, MD and Swerdlow, Daniel I., MBBS, PhD and Kuchenbaecker, Karoline B., Dipl Psych, MSc and Staines-Urias, Eleonora, MD, MSc and Goel, Anuj, MSc and van 't Hooft, Ferdinand, MD, PhD and Gertow, Karl, PhD and de Faire, Ulf, MD, PhD and Panayiotou, Andrie G., PhD and Tremoli, Elena, PhD and Baldassarre, Damiano, PhD and Veglia, Fabrizio, PhD and Holdt, Lesca M., MD, PhD and Beutner, Frank, MD, PhD and Gansevoort, Ron T., MD, PhD and Navis, Gerjan J., MD, PhD and Mateo Leach, Irene, PhD and Breitling, Lutz P., MD and Brenner, Hermann, MD, MPH and Thiery, Joachim, MD, MBA and Dallmeier, Dhayana, MD and Franco-Cereceda, Anders, MD, PhD and Boer, Jolanda M.A., PhD and Stephens, Jeffrey W., PhD and Hofker, Marten H., PhD and Tedgui, Alain, PhD and Hofman, Albert, MD, PhD and Uitterlinden, André G., PhD and Adamkova, Vera, MD, PhD and Pitha, Jan, MD, PhD and Onland-Moret, N. Charlotte, PhD and Cramer, Maarten J., MD, PhD and Nathoe, Hendrik M., MD, PhD and Spiering, Wilko, MD, PhD and Klungel, Olaf H., PharmD, PhD and Kumari, Meena, PhD and Whincup, Peter H and Morrow, David A., MD and Braund, Peter S., MSc and Hall, Alistair S., PhD and Olsson, Anders G., MD, PhD and Doevendans, Pieter A., MD, PhD and Trip, Mieke D., MD, PhD and Tobin, Martin D., PhD and Hamsten, Anders, PhD and Watkins, Hugh, PhD and Koenig, Wolfgang, MD and Nicolaides, Andrew N., PhD and Teupser, Daniel, MD, PhD and Day, Ian N.M and Carlquist, John F., PhD and Gaunt, Tom R., PhD and Ford, Ian, PhD and Sattar, Naveed and Tsimikas, Sotirios, MD and Schwartz, Gregory G., MD PhD and Lawlor, Debbie A., PhD and Morris, Richard W., PhD and Sandhu, Manjinder S., PhD and Poledne, Rudolf, PhD and Maitland-van der Zee, Anke H., PhD and Khaw, Kay-Tee, MBBChir and Keating, Brendan J., PhD and van der Harst, Pim, MD, PhD and Price, Jackie F., MD and Mehta, Shamir R., MD, MSc and Yusuf, Salim, MBBS, DPhil and Witteman, Jaqueline C.M., PhD and Franco, Oscar H., MD, PhD and Jukema, J. Wouter, MD, PhD and de Knijff, Peter, PhD and Tybjaerg-Hansen, Anne, MD, DMSc and Rader, Daniel J., MD and Farrall, Martin, MD, PhD and Samani, Nilesh J., MD and ...
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A2 (sPLA2 )-IIA in cardiovascular disease. Background Higher circulating levels... 
Cardiovascular | Internal Medicine | drug development | epidemiology | genetics | cardiovascular diseases | Mendelian randomization | Studies | Cardiovascular disease | Heart attacks | Drug therapy | Mortality | Cholesterol
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7. Full Text Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study
by Van Der Laan, Sander W and Fall, Magnus and Soumaré, Aicha and Teumer, Alexander and Sedaghat, Sanaz and Baumert, Jens and Zabaneh, Delilah and Setten, Jessica and Isgum, Ivana and Galesloot, Tessel and Arpegård, Johannes and Amouyel, Philippe and Trompet, Stella and Waldenberger, Melanie and Dörr, Marcus and Magnusson, Patrik and Gieaitis, Vilmantas and Larsson, Anders and Morris, Anew and Felix, Janine and Morrison, Alanna C and Franceschini, Nora and Bis, Joshua and Kavousi, Maryam and O'Donnell, Christopher and nos, Fotios and Tragante, Vinicius and Munroe, Patricia and Malik, Rainer and Kubisch, Christian and Worrall, Bradford B and Erdmann, Jeanette and Nelson, Christopher P and Samani, Nilesh and Schunkert, Heribert and Marchini, Jonathan and Patel, Riyaz and Hingorani, Aroon and Kao, Wen and Pedersen, Nancy and Graaf, Jacqueline and Kiemeney, Bart and Baumeister, Sebastian and Franco, Oscar and Hofman, Albert and Uitterlinden, Ané and Koenig, Wolfgang and Meisinger, Christa and Peters, Annette and Thorand, Barbara and Jukema, Jan Wouter and Eriksen, Bjørn Odvar and Toft, Ingrid and Wilsgaard, Tom and Onland-Moret, N. Charlotte and Schouw, Yvonne and Debette, Stéphanie and Kumari, Meena and Svensson, Per and van der Harst, Pim and Kivimaki, Mika and Keating, John and Sattar, Naveed and Dehghan, Abbas and Reiner, Alexander and Ingelsson, Erik and Ruijter, Hester and Bakker, Paul and Pasterkamp, Gerard and Ärnlöv, Johan and Holmes, Michael and Asselbergs, Folkert and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Journal of the American College of Cardiology, ISSN 0735-1097, 08/2016, Volume 68, Issue 9, pp. 934 - 945
markdownabstract__Background__ Epidemiological studies show that high circulating cystatin C is associated with risk of cardiovascular disease (CVD),... 
heart failure | coronary heart disease | genetics | ischemic stroke | COMMON VARIANTS | CARDIAC & CARDIOVASCULAR SYSTEMS | METAANALYSIS | EVENTS | SUSCEPTIBILITY LOCI | RISK | INCIDENT HEART-FAILURE | KIDNEY-FUNCTION | BODY-MASS INDEX | ISCHEMIC-STROKE | GENOME-WIDE ASSOCIATION | Mendelian Randomization Analysis - methods | Prospective Studies | Global Health | Cystatin C - blood | Humans | Middle Aged | Risk Factors | Genotype | Cardiovascular Diseases - genetics | Incidence | Alleles | Cardiovascular Diseases - blood | Cardiovascular Diseases - epidemiology | Aged | Cystatin C - genetics | Polymorphism, Single Nucleotide | Heart failure | Stroke | Heart attacks | Cardiovascular disease | Genomes | Epidemiology | Studies | Consortia | Coronary vessels | Collaboration | Quality control | Health risk assessment | Causality | Index Medicus | Abridged Index Medicus | Samfunnsmedisin, sosialmedisin: 801 | Community medicine, Social medicine: 801 | VDP | Helsefag: 800 | Health sciences: 800 | Medisinske Fag: 700 | Medical disciplines: 700 | Clinical Medicine | Hälsa och välfärd | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Health and Welfare
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8. Full Text Secretory Phospholipase A(2)-IIA and Cardiovascular Disease
by Holmes, Michael V and Simon, Tabassome and Exeter, Holly J and Folkersen, Lasse and Asselbergs, Folkert W and Guardiola, Montse and Cooper, Jackie A and Palmen, Jutta and Hubacek, Jaroslav A and Carruthers, Kathryn F and Horne, Benjamin D and Brunisholz, Kimberly D and Mega, Jessica L and Van Iperen, Erik P. A and Li, Mingyao and Leusink, Maarten and Trompet, Stella and Verschuren, Jeffrey J. W and Hovingh, G. Kees and Dehghan, Abbas and Nelson, Christopher P and Kotti, Salma and Danchin, Nicolas and Scholz, Markus and Haase, Christiane L and Rothenbacher, Dietrich and Swerdlow, Daniel I and Kuchenbaecker, Karoline B and Staines-Urias, Eleonora and Goel, Anuj and van 't Hooft, Ferdinand and Gertow, Karl and de Faire, Ulf and Panayiotou, Anie G and Tremoli, Elena and Baldassarre, Damiano and Veglia, Fabrizio and Holdt, Lesca M and Beutner, Frank and Gansevoort, Ron T and Navis, Gerjan J and Mateo Leach, Irene and Breitling, Lutz P and Brenner, Hermann and Thiery, Joachim and Dallmeier, Dhayana and Franco-Cereceda, Anders and Boer, Jolanda M. A and Stephens, Jeffrey W and Hofker, Marten H and Tedgui, Alain and Hofman, Albert and Uitterlinden, Ane G and Adamkova, Vera and Pitha, Jan and Onland-Moret, N. Charlotte and Cramer, Maarten J and Nathoe, Henik M and Spiering, Wilko and Klungel, Olaf H and Kumari, Meena and Whincup, Peter H and Morrow, David A and Braund, Peter S and Hall, Alistair S and Olsson, Anders G and Doevendans, Pieter A and Trip, Mieke D and Tobin, Martin D and Hamsten, Anders and Watkins, Hugh and Koenig, Wolfgang and Nicolaides, Anew N and Teupser, Daniel and Day, Ian N. M and Carlquist, John F and Gaunt, Tom R and Ford, Ian and Sattar, Naveed and Tsimikas, Sotirios and Schwartz, Gregory G and Lawlor, Debbie A and Morris, Richard W and Sandhu, Manjinder S and Poledne, Rudolf and Maitland-van der Zee, Anke H and Khaw, Kay-Tee and Keating, Brendan J and van der Harst, Pim and Price, Jackie F and Mehta, Shamir R and Yusuf, Salim and Witteman, Jaqueline C. M and Franco, Oscar H and Jukema, J. Wouter and de Knijff, Peter and Tybjaerg-Hansen, Anne and Rader, Daniel J and Farrall, Martin and Samani, Nilesh J and ... and Avdelningen för kardiovaskulär medicin and Endokrinmedicinska kliniken and Linköpings universitet and Institutionen för medicin och hälsa and Hjärt- och Medicincentrum and Östergötlands Läns Landsting and Hälsouniversitetet
Journal of the American College of Cardiology, ISSN 0735-1097, 11/2013, Volume 62, Issue 21, pp. 1966 - 1976
Objectives This study sought to investigate the role of secretory phospholipase A(2) (sPLA(2))-IIA in cardiovascular disease. Background Higher circulating... 
CARDIAC & CARDIOVASCULAR SYSTEMS | EVENTS | METAANALYSIS | drug development | RISK | cardiovascular diseases | Mendelian randomization | ACUTE CORONARY SYNDROME | epidemiology | genetics | ENZYMES | SERUM-LEVELS | INHIBITOR | HEALTHY-MEN | ASSOCIATION | TEKNIKVETENSKAP | Engineering and Technology | Teknik och teknologier | TECHNOLOGY
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9. Full Text Interaction between genes and macronutrient intake on the risk of developing type 2 diabetes : Systematic review and findings from European Prospective Investigation into Cancer (EPIC)-InterAct
by Li, Sherly X and Imamura, Fumiaki and Ye, Zheng and Schulze, Matthias B and Zheng, Jusheng and Ardanaz, Eva and Arriola, Larraitz and Boeing, Heiner and Dow, Courtney and Fagherazzi, Guy and Franks, Paul W and Agudo, Antonio and Grioni, Sara and Kaaks, Rudolf and Katzke, Verena A and Key, Timothy J and Khaw, Kay Tee and Mancini, Francesca Romana and Navarro, Carmen and Nilsson, Peter M and Onland-Moret, N. Charlotte and Overvad, Kim and Palli, Domenico and Panico, Salvatore and Quirós, José Ramón and Rolandsson, Olov and Sacerdote, Carlotta and Sánchez, María José and Slimani, Nadia and Sluijs, Ivonne and Spijkerman, Annemieke M. W and Tjonneland, Anne and Tumino, Rosario and Sharp, Stephen J and Riboli, Elio and Langenberg, Claudia and Scott, Robert A and Forouhi, Nita G and Wareham, Nicholas J and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Allmänmedicin and Umeå universitet and Medicin
American Journal of Clinical Nutrition, ISSN 0002-9165, 07/2017, Volume 106, Issue 1, pp. 263 - 275
Background: Gene-diet interactions have been reported to contribute to the development of type 2 diabetes (T2D). However, to our knowledge, few examples have... 
Diet | Gene | Interaction | Effect modification | Replication | Systematic review | Diabetes | Macronutrient | replication | DIETARY-FAT | METAANALYSIS | NON-HISPANIC WHITES | gene | ENVIRONMENT INTERACTIONS | IMPAIRED GLUCOSE-TOLERANCE | CARBOHYDRATE | FATTY-ACIDS | PREVENTION PROGRAM | systematic review | NUTRITION & DIETETICS | effect modification | interaction | PHYSICAL-ACTIVITY | diet | macronutrient | diabetes | GENOME-WIDE ASSOCIATION | Dietary Fiber - pharmacology | Transcription Factor 7-Like 2 Protein - genetics | Diabetes Mellitus - genetics | Dietary Carbohydrates - pharmacology | Dipeptidases - genetics | Europe | Humans | Middle Aged | Risk Factors | Feeding Behavior | Male | Energy Intake | Gene-Environment Interaction | Case-Control Studies | Dietary Fats - pharmacology | Models, Biological | Receptors, Gastrointestinal Hormone - genetics | Diabetes Mellitus - etiology | Female | Caveolin 2 - genetics | Type 2 diabetes | Physiological aspects | Nutritional aspects | Development and progression | Research | Proteins in human nutrition | Medical research | Carbohydrates | Peptidase | Polyunsaturated fatty acids | Caveolin | Genes | Diabetes mellitus | Health risks | Clinical trials | Genomes | Dietary intake | Criteria | Regression analysis | Fatty acids | Epidemiology | Genetic variance | Biomarkers | Nutrients | Bioindicators | Dietary fiber | Cancer | Index Medicus | Abridged Index Medicus | 5003 | Gene-Nutrient Interactions | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Hälsovetenskaper | Näringslära | Medical Genetics | Medicinsk genetik | Medicinska och farmaceutiska grundvetenskaper | Nutrition and Dietetics | Health Sciences
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